-
1
-
-
84908460595
-
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin
-
Hoadley, K. A., et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell 158, 929-944 (2014
-
(2014)
Cell
, vol.158
, pp. 929-944
-
-
Hoadley, K.A.1
-
2
-
-
84973617999
-
Proteogenomics connects somatic mutations to signalling in breast cancer
-
Mertins, P., et al. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 (2016
-
(2016)
Nature
, vol.534
, pp. 55-62
-
-
Mertins, P.1
-
3
-
-
84958749958
-
An integrated metabolic atlas of clear cell renal cell carcinoma
-
Hakimi, A. A., et al. An integrated metabolic atlas of clear cell renal cell carcinoma. Cancer Cell 29, 104-116 (2016
-
(2016)
Cancer Cell
, vol.29
, pp. 104-116
-
-
Hakimi, A.A.1
-
4
-
-
84977611330
-
Integrated proteogenomic characterization of human high-grade serous ovarian cancer
-
Zhang, H., et al. Integrated proteogenomic characterization of human high-grade serous ovarian cancer. Cell 166, 755-765 (2016
-
(2016)
Cell
, vol.166
, pp. 755-765
-
-
Zhang, H.1
-
5
-
-
84958987044
-
Leveraging big data to transform target selection and drug discovery
-
Chen, B., & Butte, A. J. Leveraging big data to transform target selection and drug discovery. Clin. Pharmacol. Ther. 99, 285-297 (2015
-
(2015)
Clin. Pharmacol. Ther
, vol.99
, pp. 285-297
-
-
Chen, B.1
Butte, A.J.2
-
6
-
-
84872649832
-
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress
-
Wilmes, A., et al. Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress. J. Proteomics 79, 180-194 (2013
-
(2013)
J. Proteomics
, vol.79
, pp. 180-194
-
-
Wilmes, A.1
-
7
-
-
84964727338
-
Reduced-representation phosphosignatures measured by quantitative targeted MS capture cellular states and enable large-scale comparison of drug-induced phenotypes
-
Abelin, J. G., et al. Reduced-representation phosphosignatures measured by quantitative targeted MS capture cellular states and enable large-scale comparison of drug-induced phenotypes. Mol. Cell. Proteomics 15, 1622-1641 (2016
-
(2016)
Mol. Cell. Proteomics
, vol.15
, pp. 1622-1641
-
-
Abelin, J.G.1
-
8
-
-
33749335282
-
The connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb, J., et al. The connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313, 1929-1935 (2006
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
-
9
-
-
84946583432
-
-
LINCS. Available at
-
LINCS. NIH LINCS Program. Available at http://www.lincsproject.org
-
NIH LINCS Program
-
-
-
10
-
-
84890027846
-
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors
-
Jahchan, N. S., et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. Cancer Discov. 3, 1364-1377 (2013
-
(2013)
Cancer Discov
, vol.3
, pp. 1364-1377
-
-
Jahchan, N.S.1
-
11
-
-
84908108434
-
Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling
-
van Noort, V., et al. Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling. Cancer Res. 74, 5690-5699 (2014
-
(2014)
Cancer Res
, vol.74
, pp. 5690-5699
-
-
Van Noort, V.1
-
12
-
-
84867338003
-
Discovery and preclinical validation of drug indications using compendia of public gene expression data
-
96ra77
-
Sirota, M., et al. Discovery and preclinical validation of drug indications using compendia of public gene expression data. Sci. Transl. Med. 3, 96ra77 (2011
-
(2011)
Sci. Transl. Med
, vol.3
-
-
Sirota, M.1
-
13
-
-
85012024851
-
Silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma
-
Pessetto, Z. Y., et al. In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. Oncotarget 8, 4079-4095 (2016
-
(2016)
Oncotarget
, vol.8
, pp. 4079-4095
-
-
Pessetto, Z.Y.1
-
14
-
-
84904196560
-
Computational repositioning and preclinical validation of pentamidine for renal cell cancer
-
Zerbini, L. F., et al. Computational repositioning and preclinical validation of pentamidine for renal cell cancer. Molecular cancer therapeutics 13, 1929-1941 (2014
-
(2014)
Molecular Cancer Therapeutics
, vol.13
, pp. 1929-1941
-
-
Zerbini, L.F.1
-
15
-
-
80051831092
-
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease
-
96ra76
-
Dudley, J. T., et al. Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease. Sci. Transl. Med. 3, 96ra76 (2011
-
(2011)
Sci. Transl. Med
, vol.3
-
-
Dudley, J.T.1
-
16
-
-
84944145290
-
Connectivity map-based discovery of parbendazole reveals targetable human osteogenic pathway
-
Brum, A. M., et al. Connectivity map-based discovery of parbendazole reveals targetable human osteogenic pathway. Proc. Natl Acad. Sci. USA 112, 12711-12716 (2015
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 12711-12716
-
-
Brum, A.M.1
-
17
-
-
84927724806
-
Systematic evaluation of connectivity map for disease indications
-
Cheng, J., Yang, L., Kumar, V., & Agarwal, P. Systematic evaluation of connectivity map for disease indications. Genome Med. 6, 540 (2014
-
(2014)
Genome Med
, vol.6
, pp. 540
-
-
Cheng, J.1
Yang, L.2
Kumar, V.3
Agarwal, P.4
-
18
-
-
84925817517
-
Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia
-
Wagner, A., et al. Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia. Mol. Syst. Biol. 11, 791 (2015
-
(2015)
Mol. Syst. Biol
, vol.11
, pp. 791
-
-
Wagner, A.1
-
19
-
-
84862192766
-
ChEMBL: A large-scale bioactivity database for drug discovery
-
Gaulton, A., et al. ChEMBL: a large-scale bioactivity database for drug discovery. Nucleic Acids Res. 40, D1100-D1107 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D1100-D1107
-
-
Gaulton, A.1
-
20
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina, J., et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483, 603-607 (2012
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
-
21
-
-
84864819611
-
-
TCGA Available at
-
TCGA. The Cancer Genome Atlas. Available at https://tcga-data.nci.nih.gov
-
The Cancer Genome Atlas
-
-
-
22
-
-
84890553061
-
Inconsistency in large pharmacogenomic studies
-
Haibe-Kains, B., et al. Inconsistency in large pharmacogenomic studies. Nature 504, 389-393 (2013
-
(2013)
Nature
, vol.504
, pp. 389-393
-
-
Haibe-Kains, B.1
-
23
-
-
84886509950
-
Metrics other than potency reveal systematic variation in responses to cancer drugs
-
Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W., & Sorger, P. K. Metrics other than potency reveal systematic variation in responses to cancer drugs. Nat. Chem.l Biol. 9, 708-714 (2013
-
(2013)
Nat. Chem.l Biol
, vol.9
, pp. 708-714
-
-
Fallahi-Sichani, M.1
Honarnejad, S.2
Heiser, L.M.3
Gray, J.W.4
Sorger, P.K.5
-
24
-
-
84946230833
-
Harnessing connectivity in a large-scale smallmolecule sensitivity dataset
-
Seashore-Ludlow, B., et al. Harnessing connectivity in a large-scale smallmolecule sensitivity dataset. Cancer Discov. 5, 1210-1223 (2015
-
(2015)
Cancer Discov
, vol.5
, pp. 1210-1223
-
-
Seashore-Ludlow, B.1
-
25
-
-
84965071035
-
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs
-
Hafner, M., Niepel, M., Chung, M., & Sorger, P. K. Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs. Nat. Methods 13, 521-527 (2016
-
(2016)
Nat. Methods
, vol.13
, pp. 521-527
-
-
Hafner, M.1
Niepel, M.2
Chung, M.3
Sorger, P.K.4
-
26
-
-
0029130419
-
Effect of blocking the Na+/K+ ATPase on Ca2+ extrusion and light adaptation in mammalian retinal rods
-
Demontis, G. C., Ratto, G. M., Bisti, S., & Cervetto, L. Effect of blocking the Na+/K+ ATPase on Ca2+ extrusion and light adaptation in mammalian retinal rods. Biophys. J. 69, 439-450 (1995
-
(1995)
Biophys. J
, vol.69
, pp. 439-450
-
-
Demontis, G.C.1
Ratto, G.M.2
Bisti, S.3
Cervetto, L.4
-
27
-
-
0036158055
-
FCCP depolarizes plasma membrane potential by activating proton and Na+ currents in bovine aortic endothelial cells
-
Park, K. S., et al. FCCP depolarizes plasma membrane potential by activating proton and Na+ currents in bovine aortic endothelial cells. Pflugers Arch.y 443, 344-352 (2002
-
(2002)
Pflugers Arch.Y
, vol.443
, pp. 344-352
-
-
Park, K.S.1
-
28
-
-
70749094311
-
The atm and atr inhibitors cgk733 and caffeine suppress cyclin d1 levels and inhibit cell proliferation
-
Alao, J. P., & Sunnerhagen, P. The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation. Radiat. Oncol. 4, 51 (2009
-
(2009)
Radiat. Oncol
, vol.4
, pp. 51
-
-
Alao, J.P.1
Sunnerhagen, P.2
-
29
-
-
77958171338
-
Small-molecule inhibition of Wnt signaling through activation of casein kinase 1alpha
-
Thorne, C. A., et al. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1alpha. Nat. Chem. Biol. 6, 829-836 (2010
-
(2010)
Nat. Chem. Biol
, vol.6
, pp. 829-836
-
-
Thorne, C.A.1
-
30
-
-
84883193004
-
The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer
-
Xu, W., et al. The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer. PLoS ONE 8, e71508 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e71508
-
-
Xu, W.1
-
31
-
-
84886878398
-
Wnt signaling and hepatocarcinogenesis: Molecular targets for the development of innovative anticancer drugs
-
Pez, F., et al. Wnt signaling and hepatocarcinogenesis: molecular targets for the development of innovative anticancer drugs. J. Hepatol. 59, 1107-1117 (2013
-
(2013)
J. Hepatol
, vol.59
, pp. 1107-1117
-
-
Pez, F.1
-
32
-
-
79951483059
-
BMP signaling promotes the growth of primary human colon carcinomas in vivo
-
Lorente-Trigos, A., Varnat, F., Melotti, A., & Ruiz i Altaba, A. BMP signaling promotes the growth of primary human colon carcinomas in vivo. J. Mol. Cell Biol. 2, 318-332 (2010
-
(2010)
J. Mol. Cell Biol
, vol.2
, pp. 318-332
-
-
Lorente-Trigos, A.1
Varnat, F.2
Melotti, A.3
Ruiz, I.4
Altaba, A.5
-
33
-
-
84958646836
-
G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice
-
Li, Y., et al. G protein-coupled estrogen receptor is involved in modulating colonic motor function via nitric oxide release in C57BL/6 female mice. Neurogastroenterol. Motil. 28, 432-442 (2016
-
(2016)
Neurogastroenterol. Motil
, vol.28
, pp. 432-442
-
-
Li, Y.1
-
34
-
-
84916620650
-
RGS2 suppresses breast cancer cell growth via a MCPIP1-dependent pathway
-
Lyu, J. H., et al. RGS2 suppresses breast cancer cell growth via a MCPIP1-dependent pathway. J. Cell. Biochem. 116, 260-267 (2015
-
(2015)
J. Cell. Biochem
, vol.116
, pp. 260-267
-
-
Lyu, J.H.1
-
35
-
-
0036232664
-
Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines
-
Hao, M. W., et al. Transcription factor EGR-1 inhibits growth of hepatocellular carcinoma and esophageal carcinoma cell lines. World J. Gastroenterol. 8, 203-207 (2002
-
(2002)
World J. Gastroenterol
, vol.8
, pp. 203-207
-
-
Hao, M.W.1
-
36
-
-
0037155243
-
Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes
-
Tice, D. A., Soloviev, I., & Polakis, P. Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes. J. Biol. Chem. 277, 6118-6123 (2002
-
(2002)
J. Biol. Chem
, vol.277
, pp. 6118-6123
-
-
Tice, D.A.1
Soloviev, I.2
Polakis, P.3
-
37
-
-
84923762812
-
A new initiative on precision medicine
-
Collins, F. S., & Varmus, H. A new initiative on precision medicine. N. Engl. J. Med. 372, 793-795 (2015
-
(2015)
N. Engl. J. Med
, vol.372
, pp. 793-795
-
-
Collins, F.S.1
Varmus, H.2
-
38
-
-
84891625661
-
Molecularly targeted cancer therapy: Some lessons from the past decade
-
Huang, M., Shen, A., Ding, J., & Geng, M. Molecularly targeted cancer therapy: some lessons from the past decade. Trends Pharmacol. Sci. 35, 41-50 (2014
-
(2014)
Trends Pharmacol. Sci
, vol.35
, pp. 41-50
-
-
Huang, M.1
Shen, A.2
Ding, J.3
Geng, M.4
-
39
-
-
84908511923
-
Decade in review-Targeted therapy: Successes, toxicities and challenges in solid tumours
-
Neal, J. W., & Sledge, G. W. Decade in review-Targeted therapy: successes, toxicities and challenges in solid tumours. Nat. Rev. 11, 627-628 (2014
-
(2014)
Nat. Rev
, vol.11
, pp. 627-628
-
-
Neal, J.W.1
Sledge, G.W.2
-
40
-
-
84860455486
-
Discovery of small molecule cancer drugs: Successes, challenges and opportunities
-
Hoelder, S., Clarke, P. A., & Workman, P. Discovery of small molecule cancer drugs: successes, challenges and opportunities. Mol. Oncol. 6, 155-176 (2012
-
(2012)
Mol. Oncol
, vol.6
, pp. 155-176
-
-
Hoelder, S.1
Clarke, P.A.2
Workman, P.3
-
41
-
-
84954026435
-
Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): A multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
-
Le Tourneau, C., et al. Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial. Lancet. Oncol. 16, 1324-1334 (2015
-
(2015)
Lancet. Oncol
, vol.16
, pp. 1324-1334
-
-
Le Tourneau, C.1
-
42
-
-
84953775211
-
Mapping the effects of drugs on the immune system
-
Kidd, B. A., et al. Mapping the effects of drugs on the immune system. Nat. Biotechnol. 34, 47-54 (2016
-
(2016)
Nat. Biotechnol
, vol.34
, pp. 47-54
-
-
Kidd, B.A.1
-
43
-
-
77957044703
-
Discovery of drug mode of action and drug repositioning from transcriptional responses
-
Iorio, F., et al. Discovery of drug mode of action and drug repositioning from transcriptional responses. Proc. Natl Acad. Sci. USA 107, 14621-14626 (2010
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 14621-14626
-
-
Iorio, F.1
-
44
-
-
84979649916
-
A landscape of pharmacogenomic interactions in cancer
-
Iorio, F., et al. A landscape of pharmacogenomic interactions in cancer. Cell 166, 740-754 (2016
-
(2016)
Cell
, vol.166
, pp. 740-754
-
-
Iorio, F.1
-
45
-
-
84859187259
-
Systematic identification of genomic markers of drug sensitivity in cancer cells
-
Garnett, M. J., et al. Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 483, 570-575 (2012
-
(2012)
Nature
, vol.483
, pp. 570-575
-
-
Garnett, M.J.1
-
46
-
-
58049213923
-
Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-Tumor activity is enhanced by combination therapy
-
Yu, D. H., et al. Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-Tumor activity is enhanced by combination therapy. PLoS ONE 3, e3951 (2008
-
(2008)
PLoS ONE
, vol.3
, pp. e3951
-
-
Yu, D.H.1
-
47
-
-
84954108890
-
Pyrvinium targets cd133 in human glioblastoma brain tumor-initiating cells
-
Venugopal, C., et al. Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor-Initiating Cells. Clin. Cancer Res. 21, 5324-5337 (2015
-
(2015)
Clin. Cancer Res
, vol.21
, pp. 5324-5337
-
-
Venugopal, C.1
-
48
-
-
84879363527
-
Pyrvinium targets autophagy addiction to promote cancer cell death
-
Deng, L., et al. Pyrvinium targets autophagy addiction to promote cancer cell death. Cell Death Dis. 4, e614 (2013
-
(2013)
Cell Death Dis
, vol.4
, pp. e614
-
-
Deng, L.1
-
49
-
-
34247898998
-
Molecular profiling of docetaxel cytotoxicity in breast cancer cells: Uncoupling of aberrant mitosis and apoptosis
-
Hernandez-Vargas, H., Palacios, J., & Moreno-Bueno, G. Molecular profiling of docetaxel cytotoxicity in breast cancer cells: uncoupling of aberrant mitosis and apoptosis. Oncogene 26, 2902-2913 (2007
-
(2007)
Oncogene
, vol.26
, pp. 2902-2913
-
-
Hernandez-Vargas, H.1
Palacios, J.2
Moreno-Bueno, G.3
-
50
-
-
84885722700
-
Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines
-
ra84
-
Niepel, M., et al. Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines. Sci. Signal. 6, ra84 (2013
-
(2013)
Sci. Signal
, vol.6
-
-
Niepel, M.1
-
51
-
-
84878107076
-
Metabolomics approach for predicting response to neoadjuvant chemotherapy for breast cancer
-
Wei, S., et al. Metabolomics approach for predicting response to neoadjuvant chemotherapy for breast cancer. Mol. Oncol. 7, 297-307 (2013
-
(2013)
Mol. Oncol
, vol.7
, pp. 297-307
-
-
Wei, S.1
-
52
-
-
84962473749
-
Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research
-
Chen, B., Sirota, M., Fan-Minogue, H., Hadley, D., & Butte, A. J. Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research. BMC Med. Genomics 8(Suppl 2): S5 (2015
-
(2015)
BMC Med. Genomics
, vol.8 S5
-
-
Chen, B.1
Sirota, M.2
Fan-Minogue, H.3
Hadley, D.4
Butte, A.J.5
-
53
-
-
84880291315
-
Evaluating cell lines as tumour models by comparison of genomic profiles
-
Domcke, S., Sinha, R., Levine, D. A., Sander, C., & Schultz, N. Evaluating cell lines as tumour models by comparison of genomic profiles. Nat. Commun. 4, 2126 (2013
-
(2013)
Nat. Commun
, vol.4
, pp. 2126
-
-
Domcke, S.1
Sinha, R.2
Levine, D.A.3
Sander, C.4
Schultz, N.5
-
54
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders, S., & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010
-
(2010)
Genome Biol
, vol.11
, pp. R106
-
-
Anders, S.1
Huber, W.2
-
55
-
-
84945272320
-
Relating chemical structure to cellular response: An integrative analysis of gene expression, bioactivity, and structural data across 11, 000 compounds
-
Chen, B., et al. Relating chemical structure to cellular response: an integrative analysis of gene expression, bioactivity, and structural data across 11, 000 compounds. CPT Pharmacometrics Syst. Pharmacol. 4, 576-584 (2015
-
(2015)
CPT Pharmacometrics Syst. Pharmacol
, vol.4
, pp. 576-584
-
-
Chen, B.1
-
56
-
-
84860992007
-
Choosing the right cell line for breast cancer research
-
Holliday, D. L., & Speirs, V. Choosing the right cell line for breast cancer research. Breast Cancer Res. 13, 215 (2011
-
(2011)
Breast Cancer Res
, vol.13
, pp. 215
-
-
Holliday, D.L.1
Speirs, V.2
-
57
-
-
1342326910
-
Relevance of breast cancer cell lines as models for breast tumours: An update
-
Lacroix, M., & Leclercq, G. Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Res. Treat. 83, 249-289 (2004
-
(2004)
Breast Cancer Res. Treat
, vol.83
, pp. 249-289
-
-
Lacroix, M.1
Leclercq, G.2
-
58
-
-
84976420628
-
Gene expression inference with deep learning
-
Chen, Y., Li, Y., Narayan, R., Subramanian, A., & Xie, X. Gene expression inference with deep learning. Bioinformatics 32, 1832-1839 2016
-
(2016)
Bioinformatics
, vol.32
, pp. 1832-1839
-
-
Chen, Y.1
Li, Y.2
Narayan, R.3
Subramanian, A.4
Xie, X.5
-
59
-
-
84917736530
-
Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends characterizing systems-level drug action
-
Vidovic, D., Koleti, A., & Schurer, S. C. Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends characterizing systems-level drug action. Front. Genet. 5, 342 (2014
-
(2014)
Front. Genet
, vol.5
, pp. 342
-
-
Vidovic, D.1
Koleti, A.2
Schurer, S.C.3
-
60
-
-
84875475890
-
Evaluation of analytical methods for connectivity map data
-
Cheng, J., et al. Evaluation of analytical methods for connectivity map data. Pac. Symp. Biocomput. 2013, 5-16, (2013
-
(2013)
Pac. Symp. Biocomput
, vol.2013
, pp. 5-16
-
-
Cheng, J.1
-
61
-
-
85020403526
-
L1000cds2: Lincs l1000 characteristic direction signatures search engine
-
Duan, Q., et al. L1000CDS2: LINCS L1000 characteristic direction signatures search engine. NPJ Syst. Biol. Appl. 2, 16015 (2016
-
(2016)
NPJ Syst. Biol. Appl
, vol.2
, pp. 16015
-
-
Duan, Q.1
-
62
-
-
84901364194
-
Chemical target, and bioactive properties of allosteric modulation
-
van Westen, G. J., Gaulton, A., & Overington, J. P. Chemical, target, and bioactive properties of allosteric modulation. PLoS Comput. Biol. 10, e1003559 (2014
-
(2014)
PLoS Comput. Biol
, vol.10
, pp. e1003559
-
-
Van Westen, G.J.1
Gaulton, A.2
Overington, J.P.3
-
63
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao, J., et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci. Signal. 6, pl1 (2013
-
(2013)
Sci. Signal
, vol.6
, pp. pl1
-
-
Gao, J.1
|