Chronic lithium treatment elicits its antimanic effects via BDNF-TRKB dependent synaptic downscaling

eLife

Volumn 6, Issue , 2017, Pages

  Gideons, Erinn S ^a,b   Lin, Pei Yi ^a   Mahgoub, Melissa ^a   Kavalali, Ege T ^a   Monteggia, Lisa M ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; LITHIUM; TROPOMYOSIN; TROPOMYOSIN RECEPTOR KINASE B; UNCLASSIFIED DRUG; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLUTAMATE RECEPTOR; TRANQUILIZER;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR CHANGE; BIPOLAR DISORDER; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; ENDOCYTOSIS; FORCED SWIM TEST; GENE EXPRESSION; HOMEOSTASIS; IN VIVO STUDY; LOCOMOTION; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; TRANSCRIPTION REGULATION; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; DRUG EFFECTS; HIPPOCAMPUS; METABOLISM; NERVE CELL; PATCH CLAMP TECHNIQUE; PHYSIOLOGY;

ANIMALS; ANTIMANIC AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; HIPPOCAMPUS; LITHIUM; MICE, INBRED C57BL; NEURONS; PATCH-CLAMP TECHNIQUES; RECEPTOR, TRKB; RECEPTORS, GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 85023636158     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.25480     Document Type: Article

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