Building a better dynasore: The dyngo compounds potently inhibit dynamin and endocytosis

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Volumn 14, Issue 12, 2013, Pages 1272-1289

  Mccluskey, Adam ^a   Daniel, James A ^b   Hadzic, Gordana ^a   Chau, Ngoc ^b   Clayton, Emma L ^c   Mariana, Anna ^b   Whiting, Ainslie ^b   Gorgani, Nick N ^b   Lloyd, Jonathan ^b   Quan, Annie ^b   Moshkanbaryans, Lia ^b   Krishnan, Sai ^b   Perera, Swetha ^b   Chircop, Megan ^b   von Kleist, Lisa ^d   Mcgeachie, Andrew B ^e   Howes, Mark T ^f   Parton, Robert G ^f   Campbell, Michael ^g   Sakoff, Jennette A ^h   Wang, Xuefeng ⁱ   Sun, Jian Yuan ⁱ   Robertson, Mark J ^a   Deane, Fiona M ^a   Nguyen, Tam H ^f   Meunier, Frederic A ^f   Cousin, Michael A ^c   Robinson, Phillip J ^b   more..

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

^f UNIVERSITY OF QUEENSLAND   (Australia)

^g MONASH UNIVERSITY   (Australia)

^h CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

ⁱ INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Bulk endocytosis; Drug discovery; Dynamin; High throughput screening; Small molecule inhibitors; Synaptic vesicle endocytosis

Indexed keywords

AMPHIPHYSIN; ANTINEOPLASTIC AGENT; CHOLERA TOXIN; CLATHRIN; CLATHRIN HEAVY CHAIN; DETERGENT; DYNAMIN; DYNAMIN I; DYNAMIN II; DYNASORE DERIVATIVE; DYNGO; DYNGO COMPOUND; HYDROLASE INHIBITOR; TRANSFERRIN; UNCLASSIFIED DRUG;

ARTICLE; CELL TYPE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; ENDOCYTOSIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; SYNAPTOSOME;

BULK ENDOCYTOSIS; DRUG DISCOVERY; DYNAMIN; HIGH-THROUGHPUT SCREENING; SMALL-MOLECULE INHIBITORS; SYNAPTIC VESICLE ENDOCYTOSIS;

ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CHOLERA TOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; DYNAMINS; ENDOCYTOSIS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; HYDRAZONES; NAPHTHOLS; NEURONS; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; SHEEP; SYNAPTIC VESICLES; TRANSFERRINS;

EID: 84887610283     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/tra.12119     Document Type: Article

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