Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway

Free Radical Biology and Medicine

Volumn 110, Issue , 2017, Pages 432-443

  Shan, Meihua ^a,b   Qin, Junfang ^a   Jin, Fengjiao ^a   Han, Xiao ^a   Guan, Haitao ^a   Li, Xiaoge ^a   Zhang, Jiahui ^a   Zhang, Hongyao ^a   Wang, Yue ^a  

^a NANKAI UNIVERSITY   (China)

^b HEBEI NORMAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

Autophagy; Breast cancer; Isoprenaline; M2 macrophage; ROS

Indexed keywords

BECLIN 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; ISOPRENALINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; 3-METHYLADENINE; ADENINE; ANTINEOPLASTIC ANTIBIOTIC; HIF1A PROTEIN, MOUSE; MAP1LC3 PROTEIN, MOUSE; MICROTUBULE ASSOCIATED PROTEIN; MTOR PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER GROWTH; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; IN VIVO STUDY; INCUBATION TIME; LUNG METASTASIS; MACROPHAGE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; RAW 264.7 CELL LINE; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DRUG EFFECTS; EPITHELIUM CELL; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG TUMOR; MAPK SIGNALING; METABOLISM; PATHOLOGY; SECONDARY; TUMOR CELL LINE;

ADENINE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; AUTOPHAGY; CELL LINE, TUMOR; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOPROTERENOL; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICROTUBULE-ASSOCIATED PROTEINS; RAW 264.7 CELLS; REACTIVE OXYGEN SPECIES; SIROLIMUS; STAT3 TRANSCRIPTION FACTOR; TOR SERINE-THREONINE KINASES; TUMOR MICROENVIRONMENT;

EID: 85023600995     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2017.05.021     Document Type: Article

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