Induction of murine macrophage m2 polarization by cigarette smoke extract via the JAK2/STAT3 pathway

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Yuan, Fengjiao ^a   Fu, Xiao ^a,b   Shi, Hengfei ^a   Chen, Guopu ^a   Dong, Ping ^a   Zhang, Weiyun ^a  

^a NANJING UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD163 ANTIGEN; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 6; JANUS KINASE 2; MESSENGER RNA; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; JAK2 PROTEIN, MOUSE; PLANT EXTRACT; STAT3 PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; HOST RESISTANCE; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTE; PHENOTYPE; POLARIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SMOKING; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FLOW CYTOMETRY; GENETICS; MALE; METABOLISM; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TOBACCO; WESTERN BLOTTING;

MURINAE;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; FLOW CYTOMETRY; JANUS KINASE 2; MACROPHAGES, ALVEOLAR; MALE; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TOBACCO;

EID: 84910610298     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107063     Document Type: Article

References (41)

1. Barnes PJ (2008) Immunology of asthma and chronic obstructive pulmonary disease. Nat Rev Immunol 8:1: 83-192.
2. Boonsarngsuk V, Suwatanapongched T, Rochanawutanon M (2009) Bronchial anthracostenosis with mediastinal fibrosis associated with long-term wood-smoke exposure. Respirology 14: 1060-1063.
3. Jyrkkiö S, Boström P, Minn H (2012) Smoking and cancer - what are the benefits of cessation? Duodecim 128: 1081-1087.
4. Salaspuro M (2012) Interactions of alcohol and tobacco in gastrointestinal cancer. J Gastroenterol Hepatol 27 Suppl 2: 135-139.
5. Satarug S (2012) Long-term exposure to cadmium in food and cigarette smoke, liver effects and hepatocellular carcinoma. Curr Drug Metab 13: 257-271.
6. Wittel UA, Momi N, Seifert G, Wiech T, Hopt UT, et al. (2012) The pathobiological impact of cigarette smoke on pancreatic cancer development (review). Int J Oncol 41: 5-14.
7. Mann CJ, Perdiguero E, Kharraz Y, Aguilar S, Pessina P, et al. (2011) Aberrant repair and fibrosis development in skeletal muscle. Skelet Muscle 1: 21.
8. Gordon S, Taylor PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5: 953-964.
9. Hao NB, Lü MH, Fan YH, Cao YL, Zhang ZR, et al. (2012) Macrophages in tumor microenvironments and the progression of tumors. Clin Dev Immuno 2012: 948098.
10. Mantovani A, Schioppa T, Biswas SK, Marchesi F, Allavena P, et al. (2003) Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations. Tumori 89: 459-468.
11. Sica A, Mantovani A (2012) Macrophage plasticity and polarization: in vivo veritas. J Clin Invest 122: 787-795.
12. Ruhrberg C, De Palma M (2010) A double agent in cancer: deciphering macrophage roles in human tumors. Nat Med 16: 861-862.
13. Ohri CM, Shikotra A, Green RH, Waller DA, Bradding P (2009) Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival. Eur Respir J 33: 118-126.
14. Yuan F, Dong P, Wang X, Fu X, Dai M, et al. (2013) Toxicological effects of cigarette smoke on Ana-1 macrophages in vitro. Exp Toxicol Pathol 65: 1011-8.
15. Sierra-Filardi E, Vega MA, Sanchez-Mateos P, Corbi AL, Puig-Kroger A (2010) Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release. Immunobiology 215: 788-795.
16. Chen W, Zhang W, Shen W, Wang K (2010) Effects of the acid polysaccharide fraction isolated from a cultivated Cordyceps sinensis on macrophages in vitro. Cell Immunol 262: 69-74.
17. Shapiro SD (1999) The macrophage in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 160(5 Pt 2): S29-32.
18. Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, et al.(2009) Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci 29: 13435-13444.
19. Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555.
20. MacMicking J, Xie QW, Nathan C (1997) Nitric oxide and macrophage function. Annu Rev Immunol 15: 323-350.
21. Covarrubias A, Byles V, Horng T (2013) ROS sets the stage for macrophage differentiation. Cell Res 23: 984-5.
22. Fabriek BO, Dijkstra CD, van den Berg TK (2005) The macrophage scavenger receptor CD163. Immunobiology 210: 153-160.
23. Hodge S, Matthews G, Mukaro V, Ahern J, Shivam A, et al. (2011) Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine. Am J Respir Cell Mol Biol 44: 673-681.
24. Kunz LI, Lapperre TS, Snoeck-Stroband JB, Budulac SE, Timens W, et al. (2011) Smoking status and anti-inflammatory macrophages in bronchoalveolar lavage and induced sputum in COPD. Respir Res 12: 34.
25. Looyenga BD, Hutchings D, Cherni I, Kingsley C, Weiss GJ, et al. (2012) STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma. PLoS One 7: e30820.
26. Lin HY, Chiang CH, Hung WC (2013) STAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cells. Br J Cancer 109: 731-8.
27. Zhao X, Sun X, Li XL (2012) Expression and clinical significance of STAT3, PSTAT3, and VEGF-C in small cell lung cancer. Asian Pac J Cancer Prev 13: 2873-2877.
28. Takeda K, Clausen BE, Kaisho T, Tsujimura T, Terada N, et al. (1999) Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10: 39-49.
29. Matsukawa A, Takeda K, Kudo S, Maeda T, Kagayama M, et al. (2003) Aberrant inflammation and lethality to septic peritonitis in mice lacking STAT3 in macrophages and neutrophils. J Immunol 171: 6198-6205.
30. Yu Z, Zhang W, Kone BC (2002) Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem J 367: 97-105.
31. Luo YP, Zhou H, Krueger J, Kaplan C, Liao D, et al. (2010) The role of protooncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression. Oncogene 29: 662-673.
32. Colomiere M, Ward AC, Riley C, Trenerry MK, Cameron-Smith D, et al. (2009) Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial-mesenchymal transition in ovarian carcinomas. Br J Cancer 100: 134-144.
33. Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, et al. (2009) IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15: 103-113.
34. Isomoto H (2009) Epigenetic alterations in cholangiocarcinoma-sustained IL-6/ STAT3 signaling in cholangio-carcinoma due to SOCS3 epigenetic silencing. Digestion 79 Suppl 1: 2-8.
35. Wang HC, Yeh HH, Huang WL, Lin CC, Su WP, et al. (2009) Activation of the signal transducer and activator of transcription 3 pathway up-regulates estrogen receptor-beta expression in lung adenocarcinoma cells. Mol Endocrinol 25: 1145-1158.
36. Fielding CA, McLoughlin RM, McLeod L, Colmont CS, Najdovska M, et al. (2008) IL-6 regulates neutrophil trafficking during acute inflammation via STAT3. J Immuno 181(3):2189-2195.
37. Matsukawa A, Kudo S, Maeda T, Numata K, Watanabe H, et al. (2005) Stat3 in resident macrophages as a repressor protein of inflammatory response. J Immunol 175: 3354-3359.
38. de Jonge WJ, van der Zanden EP, The FO, Bijlsma MF, van Westerloo DJ, et al. (2005) Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol 6: 844-851.
39. Wang K, Wu YG, Su J, Zhang JJ, Zhang P, et al. (2012) Total glucosides of paeony regulates JAK2/STAT3 activation and macrophage proliferation in diabetic rat kidneys. Am J Chin Med 40: 521-536.
40. Hasita H, Komohara Y, Okabe H, Masuda T, Ohnishi K, et al. (2010) Significance of alternatively activated macrophages in patients with intrahepatic cholangiocarcinoma. Cancer Sci 101: 1913-1919.
41. Fujiwara Y, Komohara Y, Kudo R, Tsurushima K, Ohnishi K, et al. (2011) Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. Oncol Rep 26: 1533-1537.