-
3
-
-
84963670568
-
Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator
-
Bowden, J., Davey Smith, G., Haycock, P. C., & Burgess, S. (2016). Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator. Genetic Epidemiology, 40, 304–314.
-
(2016)
Genetic Epidemiology
, vol.40
, pp. 304-314
-
-
Bowden, J.1
Davey Smith, G.2
Haycock, P.C.3
Burgess, S.4
-
4
-
-
84936776179
-
Network Mendelian randomization: Using genetic variants as instrumental variables to investigate mediation in causal pathways
-
Burgess, S., Daniel, R. M., Butterworth, A. S., Thompson, S. G., & EPIC-InterAct Consortium. (2015). Network Mendelian randomization: Using genetic variants as instrumental variables to investigate mediation in causal pathways. International Journal of Epidemiology, 44, 484–495.
-
(2015)
International Journal of Epidemiology
, vol.44
, pp. 484-495
-
-
Burgess, S.1
Daniel, R.M.2
Butterworth, A.S.3
Thompson, S.G.4
-
5
-
-
84942244702
-
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
-
Cordell, H. J., Han, Y., Mells, G. F., Li, Y., Hirschfield, G. M., Greene, C. S., … Siminovitch, K. A. (2015). International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. Nature Communications, 6, 8019.
-
(2015)
Nature Communications
, vol.6
, pp. 8019
-
-
Cordell, H.J.1
Han, Y.2
Mells, G.F.3
Li, Y.4
Hirschfield, G.M.5
Greene, C.S.6
Siminovitch, K.A.7
-
7
-
-
84893162063
-
Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer
-
Koestler, D. C., Chalise, P., Cicek, M. S., Cunningham, J. M., Armasu, S., Larson, M. C., … Goode, E. L. (2014). Integrative genomic analysis identifies epigenetic marks that mediate genetic risk for epithelial ovarian cancer. BMC Medical Genomics, 7, 8.
-
(2014)
BMC Medical Genomics
, vol.7
, pp. 8
-
-
Koestler, D.C.1
Chalise, P.2
Cicek, M.S.3
Cunningham, J.M.4
Armasu, S.5
Larson, M.C.6
Goode, E.L.7
-
8
-
-
84873576566
-
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis
-
Liu, Y., Aryee, M. J., Padyukov, L., Fallin, M. D., Hesselberg, E., Runarsson, A., … Feinberg, A. P. (2013). Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nature Biotechnology, 31, 142–147.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 142-147
-
-
Liu, Y.1
Aryee, M.J.2
Padyukov, L.3
Fallin, M.D.4
Hesselberg, E.5
Runarsson, A.6
Feinberg, A.P.7
-
10
-
-
67650258730
-
Disentangling molecular relationships with a causal inference test
-
Millstein, J., Zhang, B., Zhu, J., & Schadt, E. E. (2009). Disentangling molecular relationships with a causal inference test. BMC Genetics, 10, 23.
-
(2009)
BMC Genetics
, vol.10
, pp. 23
-
-
Millstein, J.1
Zhang, B.2
Zhu, J.3
Schadt, E.E.4
-
11
-
-
84988434151
-
Predicting gene targets from integrative analyses of summary data from gwas and eQTL studies for 28 human complex traits
-
Pavlides, J. M., Zhu, Z., Gratten, J., McRae, A. F., Wray, N. R., & Yang, J. (2016). Predicting gene targets from integrative analyses of summary data from gwas and eQTL studies for 28 human complex traits. Genome Medicine, 8, 84.
-
(2016)
Genome Medicine
, vol.8
, pp. 84
-
-
Pavlides, J.M.1
Zhu, Z.2
Gratten, J.3
McRae, A.F.4
Wray, N.R.5
Yang, J.6
-
12
-
-
84994115572
-
Challenges and novel approaches for investigating molecular mediation
-
Richmond, R., Hemani, G., Tilling, K., Smith, G. D., & Relton, C. (2016). Challenges and novel approaches for investigating molecular mediation. Human Molecular Genetics, 25, R149–R156.
-
(2016)
Human Molecular Genetics
, vol.25
, pp. R149-R156
-
-
Richmond, R.1
Hemani, G.2
Tilling, K.3
Smith, G.D.4
Relton, C.5
-
13
-
-
0000120766
-
Estimating the dimension of a model
-
Schwarz, G. (1978). Estimating the dimension of a model. Annals of Statistics, 6, 461–464.
-
(1978)
Annals of Statistics
, vol.6
, pp. 461-464
-
-
Schwarz, G.1
-
14
-
-
77955124773
-
Learning Bayesian networks with the bnlearn R package
-
Scutari, M. (2010). Learning Bayesian networks with the bnlearn R package. Journal of Statistical Software, 35, 1–22.
-
(2010)
Journal of Statistical Software
, vol.35
, pp. 1-22
-
-
Scutari, M.1
-
15
-
-
84902006099
-
Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids
-
Shin, S.-Y., Petersen, A.-K., Wahl, S., Zhai, G., Römisch-Margl, W., Small, K. S., … Soranzo, N. (2014). Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids. Genome Medicine, 6, 25.
-
(2014)
Genome Medicine
, vol.6
, pp. 25
-
-
Shin, S.-Y.1
Petersen, A.-K.2
Wahl, S.3
Zhai, G.4
Römisch-Margl, W.5
Small, K.S.6
Soranzo, N.7
-
17
-
-
0037322022
-
Mendelian randomization: Can genetic epidemiology contribute to understanding environmental determinants of disease?
-
Smith, G. D., & Ebrahim, S. (2003). Mendelian randomization: Can genetic epidemiology contribute to understanding environmental determinants of disease? International Journal of Epidemiology, 32, 1–22.
-
(2003)
International Journal of Epidemiology
, vol.32
, pp. 1-22
-
-
Smith, G.D.1
Ebrahim, S.2
-
18
-
-
84906838227
-
Mendelian randomization: Genetic anchors for causal inference in epidemiological studies
-
Smith, G. D., & Hemani, G. (2014). Mendelian randomization: Genetic anchors for causal inference in epidemiological studies. Human Molecular Genetics, 23, R89–R98.
-
(2014)
Human Molecular Genetics
, vol.23
, pp. R89-R98
-
-
Smith, G.D.1
Hemani, G.2
-
19
-
-
84879818733
-
A unified framework for association analysis with multiple related phenotypes
-
Stephens, M. (2013). A unified framework for association analysis with multiple related phenotypes. PloS One, 8, e65245.
-
(2013)
PloS One
, vol.8
-
-
Stephens, M.1
-
20
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher, P. M., Brown, M. A., McCarthy, M. I., & Yang, J. (2012). Five years of GWAS discovery. American Journal of Human Genetics, 90, 7–24.
-
(2012)
American Journal of Human Genetics
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
Brown, M.A.2
McCarthy, M.I.3
Yang, J.4
-
21
-
-
85011684926
-
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
-
Wain, L. V., Shrine, N., Artigas, M. S., Erzurumluoglu, A. M., Noyvert, B., Bossini-Castillo, L., … Tobin, M. D. (2017). Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49, 416–425.
-
(2017)
Nature Genetics
, vol.49
, pp. 416-425
-
-
Wain, L.V.1
Shrine, N.2
Artigas, M.S.3
Erzurumluoglu, A.M.4
Noyvert, B.5
Bossini-Castillo, L.6
Tobin, M.D.7
-
22
-
-
85010952930
-
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
-
Warren, H. R., Evangelou, E., Cabrera, C. P., Gao, H., Ren, M., Mifsud, B., … UK Biobank CardioMetabolic Consortium BP working group. (2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nature Genetics, 49, 403–415.
-
(2017)
Nature Genetics
, vol.49
, pp. 403-415
-
-
Warren, H.R.1
Evangelou, E.2
Cabrera, C.P.3
Gao, H.4
Ren, M.5
Mifsud, B.6
-
23
-
-
84981485021
-
A causal network analysis of the fatty acid metabolome in African-Americans reveals a critical role for palmitoleate and margarate
-
Yazdani, A., Yazdani, A., & Boerwinkle, E. (2016a). A causal network analysis of the fatty acid metabolome in African-Americans reveals a critical role for palmitoleate and margarate. OMICS: A Journal of Integrative Biology, 20, 480–484.
-
(2016)
OMICS: A Journal of Integrative Biology
, vol.20
, pp. 480-484
-
-
Yazdani, A.1
Yazdani, A.2
Boerwinkle, E.3
-
24
-
-
84962866775
-
Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data
-
Yazdani, A., Yazdani, A., Samiei, A., & Boerwinkle, E. (2016b). Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data. Journal of Biomedical Informatics, 60, 114–119.
-
(2016)
Journal of Biomedical Informatics
, vol.60
, pp. 114-119
-
-
Yazdani, A.1
Yazdani, A.2
Samiei, A.3
Boerwinkle, E.4
-
25
-
-
84987904669
-
Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study
-
Yazdani, A., Yazdani, A., Samiei, A., & Boerwinkle, E. (2016c). Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study. Journal of Biomedical Informatics, 63, 337–343.
-
(2016)
Journal of Biomedical Informatics
, vol.63
, pp. 337-343
-
-
Yazdani, A.1
Yazdani, A.2
Samiei, A.3
Boerwinkle, E.4
-
26
-
-
84971333790
-
A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels
-
Yazdani, A., Yazdani, A., Saniei, A., & Boerwinkle, E. (2016d). A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels. Metabolomics, 12, 1–7.
-
(2016)
Metabolomics
, vol.12
, pp. 1-7
-
-
Yazdani, A.1
Yazdani, A.2
Saniei, A.3
Boerwinkle, E.4
-
27
-
-
3242806720
-
An integrative genomics approach to the reconstruction of gene networks in segregating populations
-
Zhu, J., Lum, P. Y., Lamb, J., GuhaThakurta, D., Edwards, S. W., Thieringer, R., … Schadt, E. E. (2004). An integrative genomics approach to the reconstruction of gene networks in segregating populations. Cytogenetic and Genome Research, 105, 363–374.
-
(2004)
Cytogenetic and Genome Research
, vol.105
, pp. 363-374
-
-
Zhu, J.1
Lum, P.Y.2
Lamb, J.3
GuhaThakurta, D.4
Edwards, S.W.5
Thieringer, R.6
Schadt, E.E.7
-
28
-
-
84937865632
-
Mendelian randomization versus path models: Making causal inferences in genetic epidemiology
-
Ziegler, A., Mwambi, H., & König, I. R. (2015). Mendelian randomization versus path models: Making causal inferences in genetic epidemiology. Human Heredity, 79, 194–204.
-
(2015)
Human Heredity
, vol.79
, pp. 194-204
-
-
Ziegler, A.1
Mwambi, H.2
König, I.R.3
-
29
-
-
84859959092
-
Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation
-
Zhu, J., Sova, P., Xu, Q., Dombek, K. M., Xu, E. Y., Vu, H., … Schadt, E. E. (2012). Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation. PLoS Biology, 10, e1001301.
-
(2012)
PLoS Biology
, vol.10
-
-
Zhu, J.1
Sova, P.2
Xu, Q.3
Dombek, K.M.4
Xu, E.Y.5
Vu, H.6
Schadt, E.E.7
-
30
-
-
84961927084
-
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
-
Zhu, Z., Zhang, F., Hu, H., Bakshi, A., Robinson, M. R., Powell, J. E., … Yang, J. (2016). Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nature Genetics, 48, 481–487.
-
(2016)
Nature Genetics
, vol.48
, pp. 481-487
-
-
Zhu, Z.1
Zhang, F.2
Hu, H.3
Bakshi, A.4
Robinson, M.R.5
Powell, J.E.6
Yang, J.7
|