-
1
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A. 2009;106(23):9362-7.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.23
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
2
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
-
Welter D, MacArthur J, Morales J, Burdett T, Hall P, Junkins H, Klemm A, Flicek P, Manolio T, Hindorff L et al. The NHGRI GWAS Catalog, a curated resource of SNP-trait associations. Nucleic Acids Res. 2014;42(Database issue):D1001-1006.
-
(2014)
Nucleic Acids Res.
, vol.42
, Issue.DATABASE ISSUE
, pp. D1001-D1006
-
-
Welter, D.1
MacArthur, J.2
Morales, J.3
Burdett, T.4
Hall, P.5
Junkins, H.6
Klemm, A.7
Flicek, P.8
Manolio, T.9
Hindorff, L.10
-
3
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher Peter M, Brown Matthew A, McCarthy Mark I, Yang J. Five years of GWAS discovery. Am J Hum Genet. 2012;90(1):7-24.
-
(2012)
Am J Hum Genet
, vol.90
, Issue.1
, pp. 7-24
-
-
Visscher Peter, M.1
Brown Matthew, A.2
McCarthy Mark, I.3
Yang, J.4
-
4
-
-
84907972474
-
From genome to function by studying eQTLs
-
Westra HJ, Franke L. From genome to function by studying eQTLs. Biochim Biophys Acta. 2014;1842(10):1896-902.
-
(2014)
Biochim Biophys Acta
, vol.1842
, Issue.10
, pp. 1896-1902
-
-
Westra, H.J.1
Franke, L.2
-
5
-
-
84885018609
-
Systematic identification of trans eQTLs as putative drivers of known disease associations
-
Westra H-J, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet. 2013;45(10):1238-43.
-
(2013)
Nat Genet
, vol.45
, Issue.10
, pp. 1238-1243
-
-
Westra, H-J.1
Peters, M.J.2
Esko, T.3
Yaghootkar, H.4
Schurmann, C.5
Kettunen, J.6
Christiansen, M.W.7
Fairfax, B.P.8
Schramm, K.9
Powell, J.E.10
-
6
-
-
84925089678
-
The role of regulatory variation in complex traits and disease
-
Albert FW, Kruglyak L. The role of regulatory variation in complex traits and disease. Nat Rev Genet. 2015;16(4):197-212.
-
(2015)
Nat Rev Genet
, vol.16
, Issue.4
, pp. 197-212
-
-
Albert, F.W.1
Kruglyak, L.2
-
7
-
-
84901631426
-
Bayesian test for colocalisation between pairs of genetic association studies using summary statistics
-
Giambartolomei C, Vukcevic D, Schadt EE, Franke L, Hingorani AD, Wallace C, Plagnol V. Bayesian test for colocalisation between pairs of genetic association studies using summary statistics. PLoS Genet. 2014;10(5):e1004383.
-
(2014)
PLoS Genet
, vol.10
, Issue.5
, pp. e1004383
-
-
Giambartolomei, C.1
Vukcevic, D.2
Schadt, E.E.3
Franke, L.4
Hingorani, A.D.5
Wallace, C.6
Plagnol, V.7
-
8
-
-
84959547986
-
Integrative approaches for large-scale transcriptome-wide association studies
-
Gusev A, Ko A, Shi H, Bhatia G, Chung W, Penninx BWJH, Jansen R, de Geus EJC, Boomsma DI, Wright FA et al. Integrative approaches for large-scale transcriptome-wide association studies. Nat Genet. 2016;48(3):245-52.
-
(2016)
Nat Genet
, vol.48
, Issue.3
, pp. 245-252
-
-
Gusev, A.1
Ko, A.2
Shi, H.3
Bhatia, G.4
Chung, W.5
Penninx, B.W.J.H.6
Jansen, R.7
de Geus, E.J.C.8
Boomsma, D.I.9
Wright, F.A.10
-
9
-
-
84940780615
-
A gene-based association method for mapping traits using reference transcriptome data
-
Gamazon ER, Wheeler HE, Shah KP, Mozaffari SV, Aquino-Michaels K, Carroll RJ, Eyler AE, Denny JC, Consortium GT, Nicolae DL et al. A gene-based association method for mapping traits using reference transcriptome data. Nat Genet. 2015;47(9):1091-8.
-
(2015)
Nat Genet
, vol.47
, Issue.9
, pp. 1091-1098
-
-
Gamazon, E.R.1
Wheeler, H.E.2
Shah, K.P.3
Mozaffari, S.V.4
Aquino-Michaels, K.5
Carroll, R.J.6
Eyler, A.E.7
Denny, J.C.8
Consortium, G.T.9
Nicolae, D.L.10
-
10
-
-
84877256755
-
Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS
-
He X, Fuller CK, Song Y, Meng Q, Zhang B, Yang X, Li H. Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS. Am J Hum Genet. 2013;92(5):667-80.
-
(2013)
Am J Hum Genet
, vol.92
, Issue.5
, pp. 667-680
-
-
He, X.1
Fuller, C.K.2
Song, Y.3
Meng, Q.4
Zhang, B.5
Yang, X.6
Li, H.7
-
11
-
-
84961927084
-
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
-
Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, Montgomery GW, Goddard ME, Wray NR, Visscher PM et al. Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nat Genet. 2016;48:481-7.
-
(2016)
Nat Genet.
, vol.48
, pp. 481-487
-
-
Zhu, Z.1
Zhang, F.2
Hu, H.3
Bakshi, A.4
Robinson, M.R.5
Powell, J.E.6
Montgomery, G.W.7
Goddard, M.E.8
Wray, N.R.9
Visscher, P.M.10
-
12
-
-
84988358800
-
-
Accessed 22 July
-
SMR software tool. http://www.cnsgenomics.com/software/smr/. Accessed 22 July 2016.
-
(2016)
-
-
-
13
-
-
84988317085
-
-
Accessed 22 July
-
SMR Results Database. http://www.cnsgenomics.com/shiny/SMRdb/. Accessed 22 July 2016.
-
(2016)
-
-
-
14
-
-
84898050170
-
Methodological challenges in mendelian randomization
-
VanderWeele TJ, Tchetgen Tchetgen EJ, Cornelis M, Kraft P. Methodological challenges in mendelian randomization. Epidemiology. 2014;25(3):427-35.
-
(2014)
Epidemiology
, vol.25
, Issue.3
, pp. 427-435
-
-
VanderWeele, T.J.1
Tchetgen Tchetgen, E.J.2
Cornelis, M.3
Kraft, P.4
-
15
-
-
84936745507
-
Mendelian randomization studies: a review of the approaches used and the quality of reporting
-
Boef AG, Dekkers OM, le Cessie S. Mendelian randomization studies: a review of the approaches used and the quality of reporting. Int J Epidemiol. 2015;44(2):496-511.
-
(2015)
Int J Epidemiol
, vol.44
, Issue.2
, pp. 496-511
-
-
Boef, A.G.1
Dekkers, O.M.2
Cessie, S.3
-
16
-
-
40849083720
-
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
-
Lawlor DA, Harbord RM, Sterne JA, Timpson N, Davey SG. Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med. 2008;27(8):1133-63.
-
(2008)
Stat Med
, vol.27
, Issue.8
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbord, R.M.2
Sterne, J.A.3
Timpson, N.4
Davey, S.G.5
-
17
-
-
84884973036
-
Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators
-
Pierce BL, Burgess S. Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators. Am J Epidemiol. 2013;178(7):1177-84.
-
(2013)
Am J Epidemiol
, vol.178
, Issue.7
, pp. 1177-1184
-
-
Pierce, B.L.1
Burgess, S.2
-
18
-
-
77955148591
-
Two-sample instrumental variables estimators
-
Inoue A, Solon G. Two-sample instrumental variables estimators. Rev Econ Stat. 2010;92:557-61.
-
(2010)
Rev Econ Stat.
, vol.92
, pp. 557-561
-
-
Inoue, A.1
Solon, G.2
-
19
-
-
84940771118
-
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
-
Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T et al. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat Genet. 2015;47(9):979-86.
-
(2015)
Nat Genet
, vol.47
, Issue.9
, pp. 979-986
-
-
Liu, J.Z.1
van Sommeren, S.2
Huang, H.3
Ng, S.C.4
Alberts, R.5
Takahashi, A.6
Ripke, S.7
Lee, J.C.8
Jostins, L.9
Shah, T.10
-
20
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42(12):1118-25.
-
(2010)
Nat Genet
, vol.42
, Issue.12
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
Lees, C.W.7
Balschun, T.8
Lee, J.9
Roberts, R.10
-
21
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011;43(3):246-52.
-
(2011)
Nat Genet
, vol.43
, Issue.3
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
Franke, A.4
D'Amato, M.5
Taylor, K.D.6
Lee, J.C.7
Goyette, P.8
Imielinski, M.9
Latiano, A.10
-
22
-
-
84876296688
-
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
-
Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381(9875):1371-9.
-
(2013)
Lancet.
, vol.381
, Issue.9875
, pp. 1371-1379
-
-
-
23
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert J-C, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, DeStefano AL, Bis JC, Beecham GW et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013;45(12):1452-8.
-
(2013)
Nat Genet
, vol.45
, Issue.12
, pp. 1452-1458
-
-
Lambert, J-C.1
Ibrahim-Verbaas, C.A.2
Harold, D.3
Naj, A.C.4
Sims, R.5
Bellenguez, C.6
Jun, G.7
DeStefano, A.L.8
Bis, J.C.9
Beecham, G.W.10
-
24
-
-
84961392741
-
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
-
Robinson EB, St Pourcain B, Anttila V, Kosmicki JA, Bulik-Sullivan B, Grove J, Maller J, Samocha KE, Sanders SJ, Ripke S et al. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nat Genet. 2016;48:552-5.
-
(2016)
Nat Genet.
, vol.48
, pp. 552-555
-
-
Robinson, E.B.1
St Pourcain, B.2
Anttila, V.3
Kosmicki, J.A.4
Bulik-Sullivan, B.5
Grove, J.6
Maller, J.7
Samocha, K.E.8
Sanders, S.J.9
Ripke, S.10
-
25
-
-
80053385384
-
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
-
Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI, Rietschel M, Blackwood D et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011;43(10):977-83.
-
(2011)
Nat Genet
, vol.43
, Issue.10
, pp. 977-983
-
-
Sklar, P.1
Ripke, S.2
Scott, L.J.3
Andreassen, O.A.4
Cichon, S.5
Craddock, N.6
Edenberg, H.J.7
Nurnberger, J.I.8
Rietschel, M.9
Blackwood, D.10
-
26
-
-
84879892380
-
A mega-analysis of genome-wide association studies for major depressive disorder
-
Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S et al. A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry. 2013;18(4):497-511.
-
(2013)
Mol Psychiatry
, vol.18
, Issue.4
, pp. 497-511
-
-
Ripke, S.1
Wray, N.R.2
Lewis, C.M.3
Hamilton, S.P.4
Weissman, M.M.5
Breen, G.6
Byrne, E.M.7
Blackwood, D.H.8
Boomsma, D.I.9
Cichon, S.10
-
27
-
-
84942987885
-
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease
-
Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Nelson CP, Hopewell JC et al. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet. 2015;47(10):1121-30.
-
(2015)
Nat Genet
, vol.47
, Issue.10
, pp. 1121-1130
-
-
Nikpay, M.1
Goel, A.2
Won, H.H.3
Hall, L.M.4
Willenborg, C.5
Kanoni, S.6
Saleheen, D.7
Kyriakou, T.8
Nelson, C.P.9
Hopewell, J.C.10
-
28
-
-
80053907554
-
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
-
The International Consortium for Blood Pressure Genome-Wide Association Studies. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011;478(7367):103-9.
-
(2011)
Nature.
, vol.478
, Issue.7367
, pp. 103-109
-
-
-
29
-
-
84887099827
-
Discovery and refinement of loci associated with lipid levels
-
Global Lipids Genetics Consortium. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013;45(11):1274-83.
-
(2013)
Nat Genet.
, vol.45
, Issue.11
, pp. 1274-1283
-
-
-
30
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
Morris AP, Voight BF, Teslovich TM, Ferreira T, Segre AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981-90.
-
(2012)
Nat Genet
, vol.44
, Issue.9
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
Ferreira, T.4
Segre, A.V.5
Steinthorsdottir, V.6
Strawbridge, R.J.7
Khan, H.8
Grallert, H.9
Mahajan, A.10
-
31
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105-16.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
Saxena, R.4
Soranzo, N.5
Jackson, A.U.6
Wheeler, E.7
Glazer, N.L.8
Bouatia-Naji, N.9
Gloyn, A.L.10
-
32
-
-
77951711343
-
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
-
The Tobacco Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet. 2010;42(5):441-7.
-
(2010)
Nat Genet.
, vol.42
, Issue.5
, pp. 441-447
-
-
-
33
-
-
84879271608
-
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
-
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A et al. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013;340(6139):1467-71.
-
(2013)
Science
, vol.340
, Issue.6139
, pp. 1467-1471
-
-
Rietveld, C.A.1
Medland, S.E.2
Derringer, J.3
Yang, J.4
Esko, T.5
Martin, N.W.6
Westra, H.J.7
Shakhbazov, K.8
Abdellaoui, A.9
Agrawal, A.10
-
34
-
-
84893654179
-
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L
-
Benyamin B, Pourcain B, Davis OS, Davies G, Hansell NK, Brion MJ, Kirkpatrick RM, Cents RA, Franic S, Miller MB et al. Childhood intelligence is heritable, highly polygenic and associated with FNBP1L. Mol Psychiatry. 2014;19(2):253-8.
-
(2014)
Mol Psychiatry
, vol.19
, Issue.2
, pp. 253-258
-
-
Benyamin, B.1
Pourcain, B.2
Davis, O.S.3
Davies, G.4
Hansell, N.K.5
Brion, M.J.6
Kirkpatrick, R.M.7
Cents, R.A.8
Franic, S.9
Miller, M.B.10
-
35
-
-
84857356586
-
Meta-analysis of genome-wide association studies for personality
-
de Moor MH, Costa PT, Terracciano A, Krueger RF, de Geus EJ, Toshiko T, Penninx BW, Esko T, Madden PA, Derringer J et al. Meta-analysis of genome-wide association studies for personality. Mol Psychiatry. 2012;17(3):337-49.
-
(2012)
Mol Psychiatry
, vol.17
, Issue.3
, pp. 337-349
-
-
de Moor, M.H.1
Costa, P.T.2
Terracciano, A.3
Krueger, R.F.4
de Geus, E.J.5
Toshiko, T.6
Penninx, B.W.7
Esko, T.8
Madden, P.A.9
Derringer, J.10
-
36
-
-
84937399367
-
Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder
-
de Moor MH, van den Berg SM, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N et al. Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder. JAMA Psychiatry. 2015;72(7):642-50.
-
(2015)
JAMA Psychiatry
, vol.72
, Issue.7
, pp. 642-650
-
-
de Moor, M.H.1
van den Berg, S.M.2
Verweij, K.J.3
Krueger, R.F.4
Luciano, M.5
Arias Vasquez, A.6
Matteson, L.K.7
Derringer, J.8
Esko, T.9
Amin, N.10
-
37
-
-
84903820211
-
Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory
-
van den Berg SM, de Moor MH, McGue M, Pettersson E, Terracciano A, Verweij KJ, Amin N, Derringer J, Esko T, van Grootheest G et al. Harmonization of neuroticism and extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory. Behav Genet. 2014;44(4):295-313.
-
(2014)
Behav Genet
, vol.44
, Issue.4
, pp. 295-313
-
-
van den Berg, S.M.1
de Moor, M.H.2
McGue, M.3
Pettersson, E.4
Terracciano, A.5
Verweij, K.J.6
Amin, N.7
Derringer, J.8
Esko, T.9
van Grootheest, G.10
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