Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits

Genome Medicine

Volumn 8, Issue 1, 2016, Pages

  Pavlides, Jennifer M Whitehead ^a   Zhu, Zhihong ^a   Gratten, Jacob ^a   McRae, Allan F ^a   Wray, Naomi R ^a   Yang, Jian ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Complex traits; Expression quantitative trait loci (eQTL); Genome wide association studies (GWAS); Summary data based Mendelian randomization (SMR)

Indexed keywords

ANALYTIC METHOD; ARTICLE; CROHN DISEASE; EFFECT SIZE; EXPRESSION QUANTITATIVE TRAIT LOCUS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE TARGETING; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC RISK; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMAN; INTEGRATIVE ANALYSIS; LIPID ANALYSIS; ONLINE SYSTEM; PLEIOTROPY; PREDICTIVE VALUE; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE TRAIT LOCUS; RANDOMIZATION; SINGLE NUCLEOTIDE POLYMORPHISM; SUMMARY DATA BASED MENDELIAN RANDOMIZATION; ULCERATIVE COLITIS; ALZHEIMER DISEASE; AUTISM SPECTRUM DISORDER; CORONARY ARTERY DISEASE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN GENOME; INFLAMMATORY BOWEL DISEASES; PATHOLOGY; PHENOTYPE; QUANTITATIVE TRAIT; STATISTICAL MODEL;

ALZHEIMER DISEASE; AUTISM SPECTRUM DISORDER; CORONARY ARTERY DISEASE; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PLEIOTROPY; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INFLAMMATORY BOWEL DISEASES; MODELS, STATISTICAL; PHENOTYPE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE;

EID: 84988434151     PISSN: None     EISSN: 1756994X     Source Type: Journal    
DOI: 10.1186/s13073-016-0338-4     Document Type: Article

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