Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions

Nature Communications

Volumn 8, Issue , 2017, Pages

  Olivares, Orianne ^a,b,c,d,e   Mayers, Jared R ^f   Gouirand, Victoire ^a,b,c,d   Torrence, Margaret E ^f   Gicquel, Tristan ^a,b,c,d   Borge, Laurence ^a,b,c,d   Lac, Sophie ^a,b,c,d   Roques, Julie ^a,b,c,d   Lavaut, Marie Noëlle ^a,b,c,d   Berthezène, Patrice ^a,b,c,d   Rubis, Marion ^a,b,c,d   Secq, Veronique ^a,b,c,d   Garcia, Stéphane ^a,b,c,d   Moutardier, Vincent ^a,b,c,d   Lombardo, Dominique ^g   Iovanna, Juan Lucio ^a,b,c,d   Tomasini, Richard ^a,b,c,d   Guillaumond, Fabienne ^a,b,c,d   Vander Heiden, Matthew G ^f,h   Vasseur, Sophie ^a,b,c,d  

^a INSERM   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c CNRS   (France)

^d AIX MARSEILLE UNIVERSITY   (France)

^e UNIVERSITY OF GLASGOW   (United Kingdom)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g University of the Mediterranean Aix Marseille II   (France)

^h DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; PROLINE; PROLINE DEHYDROGENASE; COLLAGENASE 3; GELATINASE B; MMP13 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; P4HA3 PROTEIN, HUMAN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PRODH PROTEIN, HUMAN;

AMINO ACID; CANCER; CELLS AND CELL COMPONENTS; COLLAGEN; METABOLISM; NUTRIENT LIMITATION; OXYGEN; PHENOTYPE; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PANCREAS ADENOCARCINOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ANIMAL; CANCER TRANSPLANTATION; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANIMALS; BIOLOGICAL TRANSPORT; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLLAGEN; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 9; MICE; MICE, TRANSGENIC; NEOPLASM TRANSPLANTATION; PANCREATIC NEOPLASMS; PROCOLLAGEN-PROLINE DIOXYGENASE; PROLINE; PROLINE OXIDASE; SIGNAL TRANSDUCTION;

EID: 85022209242     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms16031     Document Type: Article

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