-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
2
-
-
34248141223
-
Tumor-stroma interactions in pancreatic ductal adenocarcinoma
-
Mahadevan D, Von Hoff DD. Tumor-stroma interactions in pancreatic ductal adenocarcinoma. Mol Cancer Ther 2007;6:1186-97.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1186-1197
-
-
Mahadevan, D.1
Von Hoff, D.D.2
-
4
-
-
0034193258
-
Role of extracellular matrix assembly in interstitial transport in solid tumors
-
Netti PA, Berk DA, Swartz MA, Grodzinsky AJ, Jain RK. Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res 2000;60:2497-503.
-
(2000)
Cancer Res
, vol.60
, pp. 2497-2503
-
-
Netti, P.A.1
Berk, D.A.2
Swartz, M.A.3
Grodzinsky, A.J.4
Jain, R.K.5
-
5
-
-
58149102321
-
Molecular basis of metastasis
-
Chiang AC, Massague J. Molecular basis of metastasis. N Engl J Med 2008;359:2814-23.
-
(2008)
N Engl J Med
, vol.359
, pp. 2814-2823
-
-
Chiang, A.C.1
Massague, J.2
-
6
-
-
0018833498
-
An investigation of the cause of death from cancer
-
Houten L, Reilley AA. An investigation of the cause of death from cancer. J Surg Oncol 1980;13:111-6.
-
(1980)
J Surg Oncol
, vol.13
, pp. 111-116
-
-
Houten, L.1
Reilley, A.A.2
-
7
-
-
84880658054
-
CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer
-
Neesse A, Frese KK, Bapiro TE, Nakagawa T, Sternlicht MD, Seeley TW, et al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A 2013;110:12325-30.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 12325-12330
-
-
Neesse, A.1
Frese, K.K.2
Bapiro, T.E.3
Nakagawa, T.4
Sternlicht, M.D.5
Seeley, T.W.6
-
8
-
-
84858602107
-
Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
-
Provenzano PP, Cuevas C, Chang AE, Goel VK, Von Hoff DD, Hingorani SR. Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 2012;21:418-29.
-
(2012)
Cancer Cell
, vol.21
, pp. 418-429
-
-
Provenzano, P.P.1
Cuevas, C.2
Chang, A.E.3
Goel, V.K.4
Von Hoff, D.D.5
Hingorani, S.R.6
-
9
-
-
83355169753
-
Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: A phase I/II trial
-
Von Hoff DD, Ramanathan RK, Borad MJ, Laheru DA, Smith LS, Wood TE, et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial. J Clin Oncol 2011;29:4548-54.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4548-4554
-
-
Von Hoff, D.D.1
Ramanathan, R.K.2
Borad, M.J.3
Laheru, D.A.4
Smith, L.S.5
Wood, T.E.6
-
10
-
-
84876993950
-
Normalizing tumor microenvironment to treat cancer: Bench to bedside to biomarkers
-
Jain RK. Normalizing tumor microenvironment to treat cancer: bench to bedside to biomarkers. J Clin Oncol 2013;31:2205-18.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2205-2218
-
-
Jain, R.K.1
-
11
-
-
84886741654
-
Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine
-
Von Hoff DD, Ervin T, Arena FP, Chiorean EG, Infante J, Moore M, et al. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med 2013;369:1691-703.
-
(2013)
N Engl J Med
, vol.369
, pp. 1691-1703
-
-
Von Hoff, D.D.1
Ervin, T.2
Arena, F.P.3
Chiorean, E.G.4
Infante, J.5
Moore, M.6
-
12
-
-
0036186862
-
Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas
-
Yen TW, Aardal NP, Bronner MP, Thorning DR, Savard CE, Lee SP, et al. Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. Surgery 2002;131:129-34.
-
(2002)
Surgery
, vol.131
, pp. 129-134
-
-
Yen, T.W.1
Aardal, N.P.2
Bronner, M.P.3
Thorning, D.R.4
Savard, C.E.5
Lee, S.P.6
-
13
-
-
0345251977
-
Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: An in vivo and in vitro study
-
Faouzi S, Le Bail B, Neaud V, Boussarie L, Saric J, Bioulac-Sage P, et al. Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study. J Hepatol 1999;30:275-84.
-
(1999)
J Hepatol
, vol.30
, pp. 275-284
-
-
Faouzi, S.1
Le Bail, B.2
Neaud, V.3
Boussarie, L.4
Saric, J.5
Bioulac-Sage, P.6
-
14
-
-
84866985855
-
Targeting the TGFbeta signalling pathway in disease
-
Akhurst RJ, Hata A. Targeting the TGFbeta signalling pathway in disease. Nat Rev Drug Discov 2012;11:790-11.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 790-711
-
-
Akhurst, R.J.1
Hata, A.2
-
15
-
-
84866557942
-
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
-
Stylianopoulos T, Martin JD, Chauhan VP, Jain SR, Diop-Frimpong B, Bardeesy N, et al. Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors. Proc Natl Acad Sci U S A 2012;109:15101-8.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 15101-15108
-
-
Stylianopoulos, T.1
Martin, J.D.2
Chauhan, V.P.3
Jain, S.R.4
Diop-Frimpong, B.5
Bardeesy, N.6
-
16
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive KP, Jacobetz MA, Davidson CJ, Gopinathan A, McIntyre D, Honess D, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009;324:1457-61.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
-
17
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010;467:1114-7.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
-
19
-
-
78650739435
-
Malignant cells facilitate lung metastasis by bringing their own soil
-
Duda DG, Duyverman AM, Kohno M, Snuderl M, Steller EJ, Fukumura D, et al. Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci U S A 2010;107:21677-82.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 21677-21682
-
-
Duda, D.G.1
Duyverman, A.M.2
Kohno, M.3
Snuderl, M.4
Steller, E.J.5
Fukumura, D.6
-
20
-
-
0020083498
-
The meaning and use of the area under a receiver operating characteristic (ROC) curve
-
Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982;143:29-36.
-
(1982)
Radiology
, vol.143
, pp. 29-36
-
-
Hanley, J.A.1
McNeil, B.J.2
-
21
-
-
84859990399
-
Effective targeting of the tumor microenvironment for cancer therapy
-
Jiang P, Li X, Thompson CB, Huang Z, Araiza F, Osgood R, et al. Effective targeting of the tumor microenvironment for cancer therapy. Anticancer Res 2012;32:1203-12.
-
(2012)
Anticancer Res
, vol.32
, pp. 1203-1212
-
-
Jiang, P.1
Li, X.2
Thompson, C.B.3
Huang, Z.4
Araiza, F.5
Osgood, R.6
-
22
-
-
84871157346
-
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
-
Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, et al. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut 2013;62:112-20.
-
(2013)
Gut
, vol.62
, pp. 112-120
-
-
Jacobetz, M.A.1
Chan, D.S.2
Neesse, A.3
Bapiro, T.E.4
Cook, N.5
Frese, K.K.6
-
23
-
-
38049103003
-
Impact of total lymph node count and lymph node ratio on staging and survival after pancreatectomy for pancreatic adenocarcinoma: A large, population-based analysis
-
Slidell MB, Chang DC, Cameron JL, Wolfgang C, Herman JM, Schulick RD, et al. Impact of total lymph node count and lymph node ratio on staging and survival after pancreatectomy for pancreatic adenocarcinoma: a large, population-based analysis. Ann Surg Oncol 2008;15:165-74.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 165-174
-
-
Slidell, M.B.1
Chang, D.C.2
Cameron, J.L.3
Wolfgang, C.4
Herman, J.M.5
Schulick, R.D.6
-
24
-
-
52149094275
-
The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
-
Erkan M, Michalski CW, Rieder S, Reiser-Erkan C, Abiatari I, Kolb A, et al. The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clin Gastroenterol Hepatol 2008;6:1155-61.
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 1155-1161
-
-
Erkan, M.1
Michalski, C.W.2
Rieder, S.3
Reiser-Erkan, C.4
Abiatari, I.5
Kolb, A.6
-
25
-
-
0032954505
-
Pancreatic stellate cells are activated by proinflammatory cytokines: Implications for pancreatic fibrogenesis
-
Apte MV, Haber PS, Darby SJ, Rodgers SC, McCaughan GW, Korsten MA, et al. Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis. Gut 1999;44:534-41.
-
(1999)
Gut
, vol.44
, pp. 534-541
-
-
Apte, M.V.1
Haber, P.S.2
Darby, S.J.3
Rodgers, S.C.4
McCaughan, G.W.5
Korsten, M.A.6
-
26
-
-
0034684279
-
Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide composition
-
Theocharis AD, Tsara ME, Papageorgacopoulou N, Karavias DD, Theocharis DA. Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide composition. Biochim Biophys Acta 2000;1502:201-6.
-
(2000)
Biochim Biophys Acta
, vol.1502
, pp. 201-206
-
-
Theocharis, A.D.1
Tsara, M.E.2
Papageorgacopoulou, N.3
Karavias, D.D.4
Theocharis, D.A.5
-
27
-
-
0033970911
-
High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer
-
Anttila MA, Tammi RH, Tammi MI, Syrjanen KJ, Saarikoski SV, Kosma VM. High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer. Cancer Res 2000;60:150-5.
-
(2000)
Cancer Res
, vol.60
, pp. 150-155
-
-
Anttila, M.A.1
Tammi, R.H.2
Tammi, M.I.3
Syrjanen, K.J.4
Saarikoski, S.V.5
Kosma, V.M.6
-
28
-
-
0033889231
-
Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival
-
Auvinen P, Tammi R, Parkkinen J, Tammi M, Agren U, Johansson R, et al. Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival. Am J Pathol 2000;156:529-36.
-
(2000)
Am J Pathol
, vol.156
, pp. 529-536
-
-
Auvinen, P.1
Tammi, R.2
Parkkinen, J.3
Tammi, M.4
Agren, U.5
Johansson, R.6
-
29
-
-
0033052479
-
Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate
-
Setala LP, Tammi MI, Tammi RH, Eskelinen MJ, Lipponen PK, Agren UM, et al. Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate. Br J Cancer 1999;79:1133-8.
-
(1999)
Br J Cancer
, vol.79
, pp. 1133-1138
-
-
Setala, L.P.1
Tammi, M.I.2
Tammi, R.H.3
Eskelinen, M.J.4
Lipponen, P.K.5
Agren, U.M.6
-
30
-
-
84859983619
-
Targeting the tumor microenvironment in cancer: Why hyaluronidase deserves a second look
-
Whatcott CJ, Han H, Posner RG, Hostetter G, Von Hoff DD. Targeting the tumor microenvironment in cancer: why hyaluronidase deserves a second look. Cancer Discov 2011;1:291-6.
-
(2011)
Cancer Discov
, vol.1
, pp. 291-296
-
-
Whatcott, C.J.1
Han, H.2
Posner, R.G.3
Hostetter, G.4
Von Hoff, D.D.5
-
31
-
-
0034776908
-
Immunohistochemical expression of extracellular matrix proteins and adhesion molecules in pancreatic carcinoma
-
Linder S, Castanos-Velez E, von Rosen A, Biberfeld P. Immunohistochemical expression of extracellular matrix proteins and adhesion molecules in pancreatic carcinoma. Hepatogastroenterology 2001;48:1321-7.
-
(2001)
Hepatogastroenterology
, vol.48
, pp. 1321-1327
-
-
Linder, S.1
Castanos-Velez, E.2
Von Rosen, A.3
Biberfeld, P.4
-
32
-
-
37349018272
-
The integrin-extracellular matrix axis in pancreatic cancer
-
Grzesiak JJ, Ho JC, Moossa AR, Bouvet M. The integrin-extracellular matrix axis in pancreatic cancer. Pancreas 2007;35:293-301.
-
(2007)
Pancreas
, vol.35
, pp. 293-301
-
-
Grzesiak, J.J.1
Ho, J.C.2
Moossa, A.R.3
Bouvet, M.4
-
33
-
-
5044238876
-
Integrin signalling during tumour progression
-
Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev Mol Cell Biol 2004;5:816-26.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 816-826
-
-
Guo, W.1
Giancotti, F.G.2
-
34
-
-
38049156416
-
Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin
-
Magzoub M, Jin S, Verkman AS. Enhanced macromolecule diffusion deep in tumors after enzymatic digestion of extracellular matrix collagen and its associated proteoglycan decorin. FASEB J 2008;22:276-84.
-
(2008)
FASEB J
, vol.22
, pp. 276-284
-
-
Magzoub, M.1
Jin, S.2
Verkman, A.S.3
-
35
-
-
84871434093
-
Clinicopathological features of 30 autopsy cases of pancreatic carcinoma
-
Matsuda Y, Hagio M, Naito Z, Ishiwata T. Clinicopathological features of 30 autopsy cases of pancreatic carcinoma. J Nippon Med Sch 2012;79:459-67.
-
(2012)
J Nippon Med Sch
, vol.79
, pp. 459-467
-
-
Matsuda, Y.1
Hagio, M.2
Naito, Z.3
Ishiwata, T.4
|