Identification of a DNA damage–induced alternative splicing pathway that regulates p53 and cellular senescence markers

Cancer Discovery

Volumn 7, Issue 7, 2017, Pages 766-781

  Chen, Jing ^a,b   Crutchley, John ^a,b   Zhang, Dadong ^b   Owzar, Kouros ^a,b   Kastan, Michael B ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; PROTEIN P53; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BINDING; RIBOSOME PROTEIN; RNA BINDING PROTEIN; RNA PRECURSOR; RPL26 PROTEIN, HUMAN; SMG1 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN;

AGING; ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; GENE PRODUCT; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPRECIPITATION; IONIZING RADIATION; MICROARRAY ANALYSIS; PROTEIN EXPRESSION; PROTEIN FOLDING; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENESCENCE; SIGNAL TRANSDUCTION; CELL AGING; CRISPR CAS SYSTEM; GENETICS; METABOLISM; RADIATION RESPONSE; TUMOR CELL LINE;

ALTERNATIVE SPLICING; CELL LINE, TUMOR; CELLULAR SENESCENCE; CRISPR-CAS SYSTEMS; DNA DAMAGE; HUMANS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; RADIATION, IONIZING; RIBOSOMAL PROTEINS; RNA PRECURSORS; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85022093326     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-16-0908     Document Type: Article

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