Disruption of the Prostaglandin Metabolome and Characterization of the Pharmaceutical Exposome in Fish Exposed to Wastewater Treatment Works Effluent As Revealed by Nanoflow-Nanospray Mass Spectrometry-Based Metabolomics

Environmental Science and Technology

Volumn 51, Issue 1, 2017, Pages 616-624

  David, Arthur ^a   Lange, Anke ^b   Abdul Sada, Alaa ^a   Tyler, Charles R ^b   Hill, Elizabeth M ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIOMOLECULES; BODY FLUIDS; DRUG PRODUCTS; EFFLUENT TREATMENT; ELECTRIC DISCHARGES; FISH; GENE EXPRESSION; LIPIDS; MASS SPECTROMETRY; METABOLISM; METABOLITES; PHYSIOLOGY; SPECTROMETRY; WASTEWATER TREATMENT;

CHEMICAL CONTAMINANTS; NANOSPRAY MASS SPECTROMETRY; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; PHYSIOLOGICAL SYSTEMS; PLASMA CONCENTRATION; SIGNALING COMPOUNDS; TRYPTOPHAN METABOLITE; WASTEWATER TREATMENT WORKS;

EFFLUENTS;

BILE ACID; CELECOXIB; DICLOFENAC; FELBINAC; IBUPROFEN; MEFENAMIC ACID; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; SEROTONIN; TRYPTOPHAN; DRUG; WASTE WATER; WATER POLLUTANT;

CONCENTRATION (COMPOSITION); CYPRINID; DISCHARGE; DRUG; EFFLUENT; ENDOCRINE DISRUPTOR; GENE EXPRESSION; MASS SPECTROMETRY; NANOTECHNOLOGY; PHYSIOLOGY; POLLUTION EXPOSURE; WASTEWATER TREATMENT;

ANIMAL EXPERIMENT; ANIMAL HEALTH; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYPRINIDAE; DRUG BLOOD LEVEL; DRUG TISSUE LEVEL; EFFLUENT; ENVIRONMENTAL EXPOSURE; EXPOSOME; FISH; GENE EXPRESSION; GENOME; LIPID METABOLISM; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; NANOFLOW NANOSPRAY MASS SPECTROMETRY; NONHUMAN; PROSTAGLANDIN SYNTHESIS; RUTILUS RUTILUS; TIME OF FLIGHT MASS SPECTROMETRY; TRYPTOPHAN METABOLISM; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WASTE WATER MANAGEMENT; ANIMAL; WASTE WATER; WATER POLLUTANT;

RUTILUS RUTILUS;

ANIMALS; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; PHARMACEUTICAL PREPARATIONS; WASTE WATER; WATER POLLUTANTS, CHEMICAL;

EID: 85021856500     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/acs.est.6b04365     Document Type: Article

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