-
1
-
-
84871586080
-
A molecular roadmap of reprogramming somatic cells into iPS cells
-
Polo, J. M. et al. A molecular roadmap of reprogramming somatic cells into iPS cells. Cell 151, 1617–1632 (2012).
-
(2012)
Cell
, vol.151
, pp. 1617-1632
-
-
Polo, J.M.1
-
2
-
-
84920720484
-
Genome-wide characterization of the routes to pluripotency
-
Hussein, S. M. et al. Genome-wide characterization of the routes to pluripotency. Nature 516, 198–206 (2014).
-
(2014)
Nature
, vol.516
, pp. 198-206
-
-
Hussein, S.M.1
-
3
-
-
84871683601
-
Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency
-
Hansson, J. et al. Highly coordinated proteome dynamics during reprogramming of somatic cells to pluripotency. Cell Rep. 2, 1579–1592 (2012).
-
(2012)
Cell Rep.
, vol.2
, pp. 1579-1592
-
-
Hansson, J.1
-
4
-
-
84906770124
-
The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming
-
Shu, X. & Pei, D. The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming. Curr. Opin. Genet. Dev. 28, 32–37 (2014).
-
(2014)
Curr. Opin. Genet. Dev.
, vol.28
, pp. 32-37
-
-
Shu, X.1
Pei, D.2
-
5
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R. et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7, 51–63 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
-
6
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani, P. et al. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7, 64–77 (2010).
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
-
7
-
-
84880330190
-
Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming
-
Liu, X. et al. Sequential introduction of reprogramming factors reveals a time-sensitive requirement for individual factors and a sequential EMT-MET mechanism for optimal reprogramming. Nat. Cell Biol. 15, 829–838 (2013).
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 829-838
-
-
Liu, X.1
-
8
-
-
70449534874
-
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells
-
Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res. 19, 1233–1242 (2009).
-
(2009)
Cell Res.
, vol.19
, pp. 1233-1242
-
-
Song, Z.1
-
9
-
-
73449100783
-
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells
-
Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells. Hepatology 51, 297–305 (2010).
-
(2010)
Hepatology
, vol.51
, pp. 297-305
-
-
Si-Tayeb, K.1
-
10
-
-
84907188829
-
Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes
-
Zhan, L. et al. Genome-wide binding and transcriptome analysis of human farnesoid X receptor in primary human hepatocytes. PLoS ONE 9, e105930 (2014).
-
(2014)
PLoS ONE
, vol.9
, pp. e105930
-
-
Zhan, L.1
-
11
-
-
84891897900
-
Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII
-
Shahani, T. et al. Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII. J. Thromb. Haemost. 12, 36–42 (2014).
-
(2014)
J. Thromb. Haemost.
, vol.12
, pp. 36-42
-
-
Shahani, T.1
-
12
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
Pan, Q., Shai, O., Lee, L. J., Frey, B. J. & Blencowe, B. J. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat. Genet. 40, 1413–1415 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
-
13
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D’Amour, K. A. et al. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23, 1534–1541 (2005).
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1534-1541
-
-
D’Amour, K.A.1
-
14
-
-
70350536767
-
A small-molecule inhibitor of Tgf-b signaling replaces Sox2 in reprogramming by inducing Nanog
-
Ichida, J. K. et al. A small-molecule inhibitor of Tgf-b signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5, 491–503 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
-
15
-
-
84887273608
-
Epithelial plasticity: A common theme in embryonic and cancer cells
-
Nieto, M. A. Epithelial plasticity: a common theme in embryonic and cancer cells. Science 342, 1234850 (2013).
-
(2013)
Science
, vol.342
, pp. 1234850
-
-
Nieto, M.A.1
-
16
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery, J. P., Acloque, H., Huang, R. Y. & Nieto, M. A. Epithelial-mesenchymal transitions in development and disease. Cell 139, 871–890 (2009).
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
17
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak, K. & Weinberg, R. A. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 9, 265–273 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
18
-
-
0038757830
-
Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis
-
Parviz, F. et al. Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis. Nat. Genet. 34, 292–296 (2003).
-
(2003)
Nat. Genet.
, vol.34
, pp. 292-296
-
-
Parviz, F.1
-
19
-
-
84856974289
-
Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4alpha transduction
-
Takayama, K. et al. Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4alpha transduction. Mol. Ther. 20, 127–137 (2012).
-
(2012)
Mol. Ther.
, vol.20
, pp. 127-137
-
-
Takayama, K.1
-
20
-
-
79960649307
-
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
-
Sekiya, S. & Suzuki, A. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature 475, 390–393 (2011).
-
(2011)
Nature
, vol.475
, pp. 390-393
-
-
Sekiya, S.1
Suzuki, A.2
-
21
-
-
84896142695
-
Direct reprogramming of human fibroblasts to functional and expandable hepatocytes
-
Huang, P. et al. Direct reprogramming of human fibroblasts to functional and expandable hepatocytes. Cell Stem Cell 14, 370–384 (2014).
-
(2014)
Cell Stem Cell
, vol.14
, pp. 370-384
-
-
Huang, P.1
-
22
-
-
0035167812
-
The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition
-
Carver, E. A., Jiang, R., Lan, Y., Oram, K. F. & Gridley, T. The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition. Mol. Cell. Biol. 21, 8184–8188 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 8184-8188
-
-
Carver, E.A.1
Jiang, R.2
Lan, Y.3
Oram, K.F.4
Gridley, T.5
-
23
-
-
84892151082
-
Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment
-
Lin, Y. et al. Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment. Nat. Commun. 5, 3070 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3070
-
-
Lin, Y.1
-
24
-
-
79955419817
-
Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs
-
Gill, J. G. et al. Snail and the microRNA-200 family act in opposition to regulate epithelial-to-mesenchymal transition and germ layer fate restriction in differentiating ESCs. Stem Cells 29, 764–776 (2011).
-
(2011)
Stem Cells
, vol.29
, pp. 764-776
-
-
Gill, J.G.1
-
25
-
-
84859210032
-
Fast gapped-read alignment with Bowtie 2
-
Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357–359 (2012).
-
(2012)
Nat. Methods
, vol.9
, pp. 357-359
-
-
Langmead, B.1
Salzberg, S.L.2
-
26
-
-
79961123152
-
RSEM: Accurate transcript quantification from RNA-Seq data with or without a reference genome
-
Li, B. & Dewey, C. N. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. BMC Bioinformatics 12, 323 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 323
-
-
Li, B.1
Dewey, C.N.2
-
27
-
-
83455238345
-
GC-content normalization for RNA-Seq data
-
Risso, D., Schwartz, K., Sherlock, G. & Dudoit, S. GC-content normalization for RNA-Seq data. BMC Bioinformatics 12, 480 (2011).
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 480
-
-
Risso, D.1
Schwartz, K.2
Sherlock, G.3
Dudoit, S.4
-
28
-
-
84988231210
-
Glbase: A framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data
-
Hutchins, A. P., Jauch, R., Dyla, M. & Miranda-Saavedra, D. glbase: a framework for combining, analyzing and displaying heterogeneous genomic and high-throughput sequencing data. Cell Regen. 3, 1 (2014).
-
(2014)
Cell Regen.
, vol.3
, pp. 1
-
-
Hutchins, A.P.1
Jauch, R.2
Dyla, M.3
Miranda-Saavedra, D.4
-
29
-
-
84866369892
-
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
-
Buganim, Y. et al. Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase. Cell 150, 1209–1222 (2012).
-
(2012)
Cell
, vol.150
, pp. 1209-1222
-
-
Buganim, Y.1
|