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Volumn 34, Issue 4, 2017, Pages 416-429

Lipid Based nanoformulation of lycopene improves oral delivery: formulation optimization, ex vivo assessment and its efficacy against breast cancer

Author keywords

antioxidant assay; box Behnken design; Lycopene; MTT assay; NLC; precirol ATO 5; stability studies

Indexed keywords

LIPID; LYCOPENE; NANOCARRIER; CAROTENOID; DRUG CARRIER; EXCIPIENT;

EID: 85021296623     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652048.2017.1340355     Document Type: Article
Times cited : (83)

References (47)
  • 1
    • 84859047530 scopus 로고    scopus 로고
    • Isolation and quantification of lycopene from tomato cultivated in Dezfoul, Iran
    • Aghel N, Ramezani Z, Amirfakhrian S., Isolation and quantification of lycopene from tomato cultivated in Dezfoul, Iran. Jundishapur J Nat Pharm Prod, 2011;6(1):9–15.
    • (2011) Jundishapur J Nat Pharm Prod , vol.6 , Issue.1 , pp. 9-15
    • Aghel, N.1    Ramezani, Z.2    Amirfakhrian, S.3
  • 2
    • 44749087481 scopus 로고    scopus 로고
    • Design and production of nanoparticles formulated from nano-emulsion templates-a review
    • Anton N, Benoit JP, Saulnier P. Design and production of nanoparticles formulated from nano-emulsion templates-a review. J Control Release, 2008;128(3):185–99.
    • (2008) J Control Release , vol.128 , Issue.3 , pp. 185-199
    • Anton, N.1    Benoit, J.P.2    Saulnier, P.3
  • 6
    • 78650546947 scopus 로고    scopus 로고
    • Optimization and formulation design of gels of diclofenac and curcumin for transdermal drug delivery by Box–Behnken statistical design
    • Chaudhary H, Kohli K, Amin S, Rathee P, Kumar V., Optimization and formulation design of gels of diclofenac and curcumin for transdermal drug delivery by Box–Behnken statistical design. J Pharm Sci, 2010;100:580–93.
    • (2010) J Pharm Sci , vol.100 , pp. 580-593
    • Chaudhary, H.1    Kohli, K.2    Amin, S.3    Rathee, P.4    Kumar, V.5
  • 8
    • 33947180400 scopus 로고    scopus 로고
    • Release modulating hydrophilic matrix systems of losartan potassium: optimization of formulation using statistical experimental design
    • Chopra S, Patil GV, Motwani SK., Release modulating hydrophilic matrix systems of losartan potassium:optimization of formulation using statistical experimental design. Eur J Pharm Biopharm, 2007;66:73–82.
    • (2007) Eur J Pharm Biopharm , vol.66 , pp. 73-82
    • Chopra, S.1    Patil, G.V.2    Motwani, S.K.3
  • 9
    • 80052099308 scopus 로고    scopus 로고
    • Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: effects of process variables
    • Das S, Ng WK, Kanaujia P, Kim S, Tan RHB., Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug:effects of process variables. Colloids Surf B Biointerfaces, 2011;88:483–9.
    • (2011) Colloids Surf B Biointerfaces , vol.88 , pp. 483-489
    • Das, S.1    Ng, W.K.2    Kanaujia, P.3    Kim, S.4    Tan, R.H.B.5
  • 10
    • 77950844756 scopus 로고    scopus 로고
    • Kinetic modeling on drug release from controlled drug delivery systems
    • Dash S, Murthy PN, Nath L, Chowdhary P. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm, 2010;67:217–23.
    • (2010) Acta Pol Pharm , vol.67 , pp. 217-223
    • Dash, S.1    Murthy, P.N.2    Nath, L.3    Chowdhary, P.4
  • 11
    • 77950281866 scopus 로고    scopus 로고
    • Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport
    • Faisal W, O’Driscoll CM, Griffin BT., Bioavailability of lycopene in the rat:the role of intestinal lymphatic transport. J Pharm Pharmacol, 2010;62:323–31.
    • (2010) J Pharm Pharmacol , vol.62 , pp. 323-331
    • Faisal, W.1    O’Driscoll, C.M.2    Griffin, B.T.3
  • 12
    • 0345390953 scopus 로고    scopus 로고
    • Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase
    • Freitas C, Müller RH., Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase. Eur J Pharm Biopharm, 1999;47:125–32.
    • (1999) Eur J Pharm Biopharm , vol.47 , pp. 125-132
    • Freitas, C.1    Müller, R.H.2
  • 13
    • 67549088287 scopus 로고    scopus 로고
    • Optimization of hydrogels for transdermal delivery of lisinopril by Box–Behnken statistical design
    • Gannu R, Yamsani VV, Yamsani SK, Palem CR, Yamsani MR. Optimization of hydrogels for transdermal delivery of lisinopril by Box–Behnken statistical design. AAPS PharmSciTech, 2009;10:505–14.
    • (2009) AAPS PharmSciTech , vol.10 , pp. 505-514
    • Gannu, R.1    Yamsani, V.V.2    Yamsani, S.K.3    Palem, C.R.4    Yamsani, M.R.5
  • 14
    • 1842292747 scopus 로고    scopus 로고
    • Lycopene is more bioavailable from tomato paste than from fresh tomatoes
    • Gartner C, Stahl W, Sies H., Lycopene is more bioavailable from tomato paste than from fresh tomatoes. Am J Clin Nutr, 1997;66:116–22.
    • (1997) Am J Clin Nutr , vol.66 , pp. 116-122
    • Gartner, C.1    Stahl, W.2    Sies, H.3
  • 16
    • 35048877561 scopus 로고    scopus 로고
    • Scanning electron microscopy study on nanoemulsions and solid lipid nanoparticles containing high amount of ceramides
    • Hatziantoniou S, Deli G, Nikas Y, Demetios C, Papaiannou GT., Scanning electron microscopy study on nanoemulsions and solid lipid nanoparticles containing high amount of ceramides. Micron, 2007;38:819–23.
    • (2007) Micron , vol.38 , pp. 819-823
    • Hatziantoniou, S.1    Deli, G.2    Nikas, Y.3    Demetios, C.4    Papaiannou, G.T.5
  • 17
    • 79952301601 scopus 로고    scopus 로고
    • Physicochemical properties of nanostructured lipid carriers as colloidal carrier system stabilized with polysorbate 20 and polysorbate 80
    • How CW, Abdullah R, Abbasalipourkabir R., Physicochemical properties of nanostructured lipid carriers as colloidal carrier system stabilized with polysorbate 20 and polysorbate 80. Afr J Biotechnol, 2011;10(9):1684–9.
    • (2011) Afr J Biotechnol , vol.10 , Issue.9 , pp. 1684-1689
    • How, C.W.1    Abdullah, R.2    Abbasalipourkabir, R.3
  • 18
    • 74249109604 scopus 로고    scopus 로고
    • Bioavailability and delivery of nutraceutical using nanotechnology. Concise reviews and hypotheses in
    • Huang Q, Yu H, Ru Q., Bioavailability and delivery of nutraceutical using nanotechnology. Concise reviews and hypotheses in. Food Sci, 2010;75(1):50–7.
    • (2010) Food Sci , vol.75 , Issue.1 , pp. 50-57
    • Huang, Q.1    Yu, H.2    Ru, Q.3
  • 19
    • 0343618485 scopus 로고    scopus 로고
    • Characterization of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids
    • Jenning V, Thunemann AF, Gohla SH., Characterization of a novel solid lipid nanoparticle carrier system based on binary mixtures of liquid and solid lipids. Int J Pharm, 2000;199:167–77.
    • (2000) Int J Pharm , vol.199 , pp. 167-177
    • Jenning, V.1    Thunemann, A.F.2    Gohla, S.H.3
  • 20
    • 0035109447 scopus 로고    scopus 로고
    • Encapsulation of retinoids in solid lipid nanoparticles (SLN)
    • Jenning V, Gohla SH., Encapsulation of retinoids in solid lipid nanoparticles (SLN). J Microencapsul, 2001;18(2):149–58.
    • (2001) J Microencapsul , vol.18 , Issue.2 , pp. 149-158
    • Jenning, V.1    Gohla, S.H.2
  • 21
    • 84860014517 scopus 로고    scopus 로고
    • The use of hot and cold high pressure homogenization to enhance the loading capacity and encapsulation efficiency of nanostructured lipid carriers for the hydrophilic antiretroviral drug, didanosine for potential administration to paediatric patients
    • Kasongo KW, Muller RH, Walker RB., The use of hot and cold high pressure homogenization to enhance the loading capacity and encapsulation efficiency of nanostructured lipid carriers for the hydrophilic antiretroviral drug, didanosine for potential administration to paediatric patients. Pharm Dev Technol, 2012;17(3):353–62.
    • (2012) Pharm Dev Technol , vol.17 , Issue.3 , pp. 353-362
    • Kasongo, K.W.1    Muller, R.H.2    Walker, R.B.3
  • 22
    • 84877337987 scopus 로고    scopus 로고
    • Engineering of a nanostructured lipid carrier for the poorly water-soluble drug, bicalutamide: physicochemical investigations
    • Kumbhar DD, Pokharkar VB., Engineering of a nanostructured lipid carrier for the poorly water-soluble drug, bicalutamide:physicochemical investigations. Colloids Surf A Physicochem Eng Aspects, 2013;416:32–42.
    • (2013) Colloids Surf A Physicochem Eng Aspects , vol.416 , pp. 32-42
    • Kumbhar, D.D.1    Pokharkar, V.B.2
  • 23
    • 0032998057 scopus 로고    scopus 로고
    • Dynamic dialysis for the drug release evaluation from doxorubicin–gelatin nanoparticle conjugates
    • Leo E, Cameroni R, Forni F., Dynamic dialysis for the drug release evaluation from doxorubicin–gelatin nanoparticle conjugates. Int J Pharm, 1999;180:23–30.
    • (1999) Int J Pharm , vol.180 , pp. 23-30
    • Leo, E.1    Cameroni, R.2    Forni, F.3
  • 24
    • 0034601240 scopus 로고    scopus 로고
    • Improving drug solubility for oral delivery using solid dispersions
    • Leuner C, Dressman J., Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm, 2000;50:47–60.
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 47-60
    • Leuner, C.1    Dressman, J.2
  • 25
    • 36348987254 scopus 로고    scopus 로고
    • Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants
    • Li HB, Wong CC, Cheng KW, Chen F., Antioxidant properties in vitro and total phenolic contents in methanol extracts from medicinal plants. Lwt, 2008;41:385–90.
    • (2008) Lwt , vol.41 , pp. 385-390
    • Li, H.B.1    Wong, C.C.2    Cheng, K.W.3    Chen, F.4
  • 26
    • 33845314297 scopus 로고    scopus 로고
    • Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery
    • Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X., Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. Int J Pharm, 2007;328(2):191–5.
    • (2007) Int J Pharm , vol.328 , Issue.2 , pp. 191-195
    • Liu, J.1    Hu, W.2    Chen, H.3    Ni, Q.4    Xu, H.5    Yang, X.6
  • 27
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: production, characterization and applications
    • Mehnert W, Mader K., Solid lipid nanoparticles:production, characterization and applications. Adv Drug Deliv Rev, 2001;47:165–96.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 29
    • 33744973517 scopus 로고    scopus 로고
    • Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLNR) versus drug nanocrystals
    • Muller RH, Runge S, Ravelli V, Mehnert W, Thunemann AF, Souto EB., Oral bioavailability of cyclosporine:solid lipid nanoparticles (SLNR) versus drug nanocrystals. Int J Pharm, 2006;317:82–9.
    • (2006) Int J Pharm , vol.317 , pp. 82-89
    • Muller, R.H.1    Runge, S.2    Ravelli, V.3    Mehnert, W.4    Thunemann, A.F.5    Souto, E.B.6
  • 30
    • 84891586984 scopus 로고    scopus 로고
    • Development of protocol for screening the formulation components and the assessment of common quality problems of nano-structured lipid carriers
    • Negi LM, Jaggi M, Talegaonkar S., Development of protocol for screening the formulation components and the assessment of common quality problems of nano-structured lipid carriers. Int J Pharm, 2014;461:403–10.
    • (2014) Int J Pharm , vol.461 , pp. 403-410
    • Negi, L.M.1    Jaggi, M.2    Talegaonkar, S.3
  • 31
    • 84884648001 scopus 로고    scopus 로고
    • Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine: ex vivo gut permeation studies
    • Neupane YR, Sabir MD, Ahmad N, Ali M, Kohli K., Lipid drug conjugate nanoparticle as a novel lipid nanocarrier for the oral delivery of decitabine:ex vivo gut permeation studies. Nanotechnology, 2013;24:415102.
    • (2013) Nanotechnology , vol.24 , pp. 415102
    • Neupane, Y.R.1    Sabir, M.D.2    Ahmad, N.3    Ali, M.4    Kohli, K.5
  • 32
    • 37749018495 scopus 로고    scopus 로고
    • Encapsulation of lycopene using spray-drying and molecular inclusion processes
    • Nunes IL, Mercadante AZ., Encapsulation of lycopene using spray-drying and molecular inclusion processes. Brazilian Arch Biol Technol, 2007;50:893–900.
    • (2007) Brazilian Arch Biol Technol , vol.50 , pp. 893-900
    • Nunes, I.L.1    Mercadante, A.Z.2
  • 33
    • 33847394968 scopus 로고    scopus 로고
    • Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
    • Porter CJH, Trevaskis NL, Charman WN., Lipids and lipid-based formulations:optimizing the oral delivery of lipophilic drugs. Nat Rev Drug Discov, 2007;6:231–48.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 231-248
    • Porter, C.J.H.1    Trevaskis, N.L.2    Charman, W.N.3
  • 34
    • 39149097505 scopus 로고    scopus 로고
    • What determines drug solubility in lipid vehicles: is it predictable?
    • Rane SS, Anderson BD., What determines drug solubility in lipid vehicles:is it predictable? Adv Drug Deliv Rev, 2008;60:638–56.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 638-656
    • Rane, S.S.1    Anderson, B.D.2
  • 35
    • 0028997258 scopus 로고
    • Skin lycopene is destroyed preferentially over beta carotene during ultraviolet irradiation in humans
    • Ribayo-Mercado JD, Garmyn M, Gilchrest BA, Russell RM., Skin lycopene is destroyed preferentially over beta carotene during ultraviolet irradiation in humans. J Nutr, 1995;125:1854–9.
    • (1995) J Nutr , vol.125 , pp. 1854-1859
    • Ribayo-Mercado, J.D.1    Garmyn, M.2    Gilchrest, B.A.3    Russell, R.M.4
  • 36
    • 1542749829 scopus 로고    scopus 로고
    • A procedure to measure the antiradical efficiency of polyphenols
    • Sánchez-Moreno C, Larrauri JA, Saura-Calixto F., A procedure to measure the antiradical efficiency of polyphenols. J Sci Food Agr, 1998;76(2):270–6.
    • (1998) J Sci Food Agr , vol.76 , Issue.2 , pp. 270-276
    • Sánchez-Moreno, C.1    Larrauri, J.A.2    Saura-Calixto, F.3
  • 37
    • 63849177475 scopus 로고    scopus 로고
    • HPLC method for determination of lycopene in crude oleoresin extracts
    • Sathish T, Udayakiran D, Himabindu K., HPLC method for determination of lycopene in crude oleoresin extracts. Asian J Chem, 2009;21(1):139–48.
    • (2009) Asian J Chem , vol.21 , Issue.1 , pp. 139-148
    • Sathish, T.1    Udayakiran, D.2    Himabindu, K.3
  • 38
    • 0037240251 scopus 로고    scopus 로고
    • Solvent injection as a new approach for manufacturing lipid nanoparticles-evaluation of the method and process parameters
    • Schubert MA, Muller-Goymann CC., Solvent injection as a new approach for manufacturing lipid nanoparticles-evaluation of the method and process parameters. Eur J Pharm Biopharm, 2003;55:125–31.
    • (2003) Eur J Pharm Biopharm , vol.55 , pp. 125-131
    • Schubert, M.A.1    Muller-Goymann, C.C.2
  • 39
    • 0032982005 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery. II. Drug incorporation and physicochemical characterization
    • Schwarz C, Mehnert W. Solid lipid nanoparticles (SLN) for controlled drug delivery. II. Drug incorporation and physicochemical characterization. J Microencapsul, 1999;16:205–13.
    • (1999) J Microencapsul , vol.16 , pp. 205-213
    • Schwarz, C.1    Mehnert, W.2
  • 40
    • 2442712381 scopus 로고    scopus 로고
    • Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery
    • Souto EB, Wissing SA, Barbosa CM, Muller RH., Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. Int J Pharm, 2004;278:71–7.
    • (2004) Int J Pharm , vol.278 , pp. 71-77
    • Souto, E.B.1    Wissing, S.A.2    Barbosa, C.M.3    Muller, R.H.4
  • 41
    • 0030474043 scopus 로고    scopus 로고
    • Lycopene: a biologically important carotenoid for humans?
    • Stahl W, Sies H., Lycopene:a biologically important carotenoid for humans? Arch Biochem Biophys, 1996;336:1–9.
    • (1996) Arch Biochem Biophys , vol.336 , pp. 1-9
    • Stahl, W.1    Sies, H.2
  • 42
    • 0031889382 scopus 로고    scopus 로고
    • Lycopene: chemistry, biology and implications for human health and disease
    • Steven K, Clinton MD., Lycopene:chemistry, biology and implications for human health and disease. Nutr Rev, 1998;56:35–51.
    • (1998) Nutr Rev , vol.56 , pp. 35-51
    • Steven, K.1    Clinton, M.D.2
  • 43
    • 84895558622 scopus 로고    scopus 로고
    • Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines
    • Takeshima M, Ono M, Higuchi T, Chen C, Hara T, Nakano S., Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines. Cancer Sci, 2014;105:252–7.
    • (2014) Cancer Sci , vol.105 , pp. 252-257
    • Takeshima, M.1    Ono, M.2    Higuchi, T.3    Chen, C.4    Hara, T.5    Nakano, S.6
  • 44
    • 33748295638 scopus 로고    scopus 로고
    • Plasma profiles of lycopene after single oral and intravenous administrations in dogs
    • Vertzoni M, Valsami G, Reppas C., Plasma profiles of lycopene after single oral and intravenous administrations in dogs. J Pharm Pharmacol, 2006;58:1211–17.
    • (2006) J Pharm Pharmacol , vol.58 , pp. 1211-1217
    • Vertzoni, M.1    Valsami, G.2    Reppas, C.3
  • 45
    • 84862285958 scopus 로고    scopus 로고
    • Lycopene, tomato products, and prostate cancer incidence: a review and reassessment in the PSA screening era
    • Wei MY, Giovannucci EL., Lycopene, tomato products, and prostate cancer incidence:a review and reassessment in the PSA screening era. J Oncol, 2012;2012:271063.
    • (2012) J Oncol , vol.2012 , pp. 271063
    • Wei, M.Y.1    Giovannucci, E.L.2
  • 46
    • 77951747208 scopus 로고    scopus 로고
    • Preparation, optimization and characteristic of huperzine A loaded nanostructured lipid carriers
    • Yang CR, Zhao X, Hu H, Li K, Sun X., Preparation, optimization and characteristic of huperzine A loaded nanostructured lipid carriers. Chem Pharm Bull, 2010;58(5):656–61.
    • (2010) Chem Pharm Bull , vol.58 , Issue.5 , pp. 656-661
    • Yang, C.R.1    Zhao, X.2    Hu, H.3    Li, K.4    Sun, X.5
  • 47
    • 65949113152 scopus 로고    scopus 로고
    • Experimental design for the optimization of lipid nanoparticles
    • Zhang J, Fan Y, Smith E., Experimental design for the optimization of lipid nanoparticles. J Pharm Sci, 2009;98(5):1813–19.
    • (2009) J Pharm Sci , vol.98 , Issue.5 , pp. 1813-1819
    • Zhang, J.1    Fan, Y.2    Smith, E.3


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