Release modulating hydrophilic matrix systems of losartan potassium: Optimization of formulation using statistical experimental design

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 66, Issue 1, 2007, Pages 73-82

  Chopra, Shruti ^a   Patil, Gayathri V ^b   Motwani, Sanjay K ^a  

^a HAMDARD UNIVERSITY   (India)

^b Global College of Pharmacy   (India)

Author keywords

Box Behnken statistical design; Hydrophilic matrix tablets; Response surface methodology; Sustained release

Indexed keywords

CARBOXYMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE; LOSARTAN POTASSIUM;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG STABILITY; HYDROPHILICITY; INFRARED SPECTROSCOPY; PROCESS OPTIMIZATION; STATISTICAL MODEL; SURFACE PROPERTY; SUSTAINED RELEASE FORMULATION; SWELLING; TABLET; VALIDATION PROCESS;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; CARBOXYMETHYLCELLULOSE; COMPRESSIVE STRENGTH; COMPUTER-AIDED DESIGN; DATA INTERPRETATION, STATISTICAL; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; EXCIPIENTS; LOSARTAN; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; TABLETS; TEMPERATURE; WETTABILITY;

EID: 33947180400     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.09.001     Document Type: Article

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