Intestinal microbial dysbiosis aggravates the progression of Alzheimer's disease in Drosophila

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Wu, Shih Cheng ^a   Cao, Zih Syuan ^a   Chang, Kuo Ming ^b   Juang, Jyh Lyh ^a,c  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b MACKAY MEMORIAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; FOCAL ADHESION KINASE; JNK PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ANTIMICROBIAL CATIONIC PEPTIDE; DROSOPHILA PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PEPTIDE FRAGMENT;

BACTERIAL DISEASE; BRAIN; FLY; IMMUNE SYSTEM; MICROBIAL ACTIVITY; OXIDATIVE STRESS; PATHOGENICITY; RISK FACTOR;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD CELL; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; DROSOPHILA; DYSBIOSIS; ENZYME ACTIVITY; FEMALE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTESTINE INFECTION; LIFESPAN; LOCOMOTION; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; QUANTITATIVE ANALYSIS; TUNEL ASSAY; ANIMAL; BRAIN; CELL MOTION; COMPLICATION; DISEASE MODEL; DROSOPHILA MELANOGASTER; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTION; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; LEUKAPHERESIS; MICROBIOLOGY; MICROFLORA; PATHOLOGY; SIGNAL TRANSDUCTION;

ENTEROBACTERIACEAE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; BRAIN; CELL MOVEMENT; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; DYSBIOSIS; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; GASTROINTESTINAL TRACT; GENE EXPRESSION REGULATION; HEMOCYTES; HUMANS; LEUKOCYTE REDUCTION PROCEDURES; MAP KINASE KINASE 4; MICROBIOTA; PEPTIDE FRAGMENTS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85021173110     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00040-6     Document Type: Article

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