Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 19, 2013, Pages

  Cao, Yang ^a   Chtarbanova, Stanislava ^a   Petersen, Andrew J ^b   Ganetzky, Barry ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Neuronal cell death; Neuroprotection; Neurotoxic mechanism

Indexed keywords

DEFENSE REPRESSOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; BRAIN INFECTION; CONTROLLED STUDY; DISEASE COURSE; DROSOPHILA; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC SCREENING; IMMUNE DEFICIENCY; INNATE IMMUNITY; LIFESPAN; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; WILD TYPE;

NEURONAL CELL DEATH; NEUROPROTECTION; NEUROTOXIC MECHANISM;

AGING; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; APOPTOSIS; BACTERIAL INFECTIONS; BRAIN; CELL DEATH; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENOTYPE; IMMUNITY, INNATE; MUTATION; NEURODEGENERATIVE DISEASES; NEURONS; PHENOTYPE; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84877348381     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1306220110     Document Type: Article

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