Supernatant from Hepatocyte Cultures with Drugs That Cause Idiosyncratic Liver Injury Activates Macrophage Inflammasomes

Chemical Research in Toxicology

Volumn 30, Issue 6, 2017, Pages 1327-1332

  Kato, Ryuji ^a,b   Uetrecht, Jack ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; CYTOCHROME P450; HIGH MOBILITY GROUP B1 PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOPEROXIDASE; NEVIRAPINE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER CELL CULTURE; MACROPHAGE ACTIVATION; PROTEIN ACETYLATION; PROTEIN METHYLATION; TOXIC HEPATITIS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; MACROPHAGE; METABOLISM; SECRETION (PROCESS); STRUCTURE ACTIVITY RELATION;

AMODIAQUINE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; HUMANS; INFLAMMASOMES; MACROPHAGES; NEVIRAPINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85020943124     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/acs.chemrestox.7b00065     Document Type: Article

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