-
1
-
-
0035147506
-
Prediction of a new drug's potential to cause idiosyncratic reactions
-
Uetrecht, J. (2001) Prediction of a new drug's potential to cause idiosyncratic reactions Curr. Opin. Drug Discovery Dev. 4, 55-59
-
(2001)
Curr. Opin. Drug Discovery Dev.
, vol.4
, pp. 55-59
-
-
Uetrecht, J.1
-
2
-
-
84925361897
-
Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA-4 leads to liver injury similar to idiosyncratic liver injury in patients
-
Metushi, I. G., Hayes, M. A., and Uetrecht, J. (2015) Treatment of PD-1(-/-) mice with amodiaquine and anti-CTLA-4 leads to liver injury similar to idiosyncratic liver injury in patients Hepatology 61, 1332-1342 10.1002/hep.27549
-
(2015)
Hepatology
, vol.61
, pp. 1332-1342
-
-
Metushi, I.G.1
Hayes, M.A.2
Uetrecht, J.3
-
3
-
-
27144496045
-
CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms
-
Parry, R. V., Chemnitz, J. M., Frauwirth, K. A., Lanfranco, A. R., Braunstein, I., Kobayashi, S. V., Linsley, P. S., Thompson, C. B., and Riley, J. L. (2005) CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms Mol. Cell. Biol. 25, 9543-9553 10.1128/MCB.25.21.9543-9553.2005
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9543-9553
-
-
Parry, R.V.1
Chemnitz, J.M.2
Frauwirth, K.A.3
Lanfranco, A.R.4
Braunstein, I.5
Kobayashi, S.V.6
Linsley, P.S.7
Thompson, C.B.8
Riley, J.L.9
-
4
-
-
84924303190
-
Comparative analysis of portal hepatic infiltrating leukocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis
-
Foureau, D. M., Walling, T. L., Maddukuri, V., Anderson, W., Culbreath, K., Kleiner, D. E., Ahrens, W. A., Jacobs, C., Watkins, P. G., and Fontana, R. J. et al. 2015, Comparative analysis of portal hepatic infiltrating leukocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis Clin. Exp. Immunol. 180, 40-51 10.1111/cei.12558
-
(2015)
Clin. Exp. Immunol.
, vol.180
, pp. 40-51
-
-
Foureau, D.M.1
Walling, T.L.2
Maddukuri, V.3
Anderson, W.4
Culbreath, K.5
Kleiner, D.E.6
Ahrens, W.A.7
Jacobs, C.8
Watkins, P.G.9
Fontana, R.J.10
-
6
-
-
85004773685
-
The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis
-
Warrington, R. J., McPhilips-Feener, S., and Rutherford, W. (1982) The predictive value of the lymphocyte transformation test in isoniazid-associated hepatitis Clin. Exp. Allergy 12, 217-222 10.1111/j.1365-2222.1982.tb02521.x
-
(1982)
Clin. Exp. Allergy
, vol.12
, pp. 217-222
-
-
Warrington, R.J.1
McPhilips-Feener, S.2
Rutherford, W.3
-
7
-
-
0018150811
-
Evaluation of isoniazid-associated hepatitis by immunological tests
-
Warrington, R. J., Tse, K. S., Gorski, B. A., Schwenk, R., and Sehon, A. H. (1978) Evaluation of isoniazid-associated hepatitis by immunological tests Clin. Exp. Immunol. 32, 97-104
-
(1978)
Clin. Exp. Immunol.
, vol.32
, pp. 97-104
-
-
Warrington, R.J.1
Tse, K.S.2
Gorski, B.A.3
Schwenk, R.4
Sehon, A.H.5
-
8
-
-
84896690558
-
Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure
-
Metushi, I. G., Sanders, C., Lee, W. M., and Uetrecht, J. (2014) Detection of anti-isoniazid and anti-cytochrome P450 antibodies in patients with isoniazid-induced liver failure Hepatology 59, 1084-1093 10.1002/hep.26564
-
(2014)
Hepatology
, vol.59
, pp. 1084-1093
-
-
Metushi, I.G.1
Sanders, C.2
Lee, W.M.3
Uetrecht, J.4
-
9
-
-
0017229380
-
Isoniazid liver injury: Clinical spectrum, pathology, and probable pathogenesis
-
Mitchell, J. R., Zimmerman, H. J., Ishak, K. G., Thorgeirsson, U. P., Timbrell, J. A., Snodgrass, W. R., and Nelson, S. D. (1976) Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis Ann. Intern. Med. 84, 181-192 10.7326/0003-4819-84-2-181
-
(1976)
Ann. Intern. Med.
, vol.84
, pp. 181-192
-
-
Mitchell, J.R.1
Zimmerman, H.J.2
Ishak, K.G.3
Thorgeirsson, U.P.4
Timbrell, J.A.5
Snodgrass, W.R.6
Nelson, S.D.7
-
10
-
-
0016757995
-
Isoniazid-associated hepatitis in 114 patients
-
Black, M., Mitchell, J. R., Zimmerman, H. J., Ishak, K. G., and Epler, G. R. (1975) Isoniazid-associated hepatitis in 114 patients Gastroenterol. 69, 289-302
-
(1975)
Gastroenterol.
, vol.69
, pp. 289-302
-
-
Black, M.1
Mitchell, J.R.2
Zimmerman, H.J.3
Ishak, K.G.4
Epler, G.R.5
-
11
-
-
84911465513
-
Isoniazid-induced liver injury and immune response in mice
-
Metushi, I. G. and Uetrecht, J. (2014) Isoniazid-induced liver injury and immune response in mice J. Immunotoxicol. 11, 383-392 10.3109/1547691X.2013.860644
-
(2014)
J. Immunotoxicol.
, vol.11
, pp. 383-392
-
-
Metushi, I.G.1
Uetrecht, J.2
-
12
-
-
84901008930
-
Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice
-
Metushi, I. G., Cai, P., Vega, L., Grant, D. M., and Uetrecht, J. (2014) Paradoxical attenuation of autoimmune hepatitis by oral isoniazid in wild-type and N-acetyltransferase-deficient mice Drug Metab. Dispos. 42, 963-973 10.1124/dmd.113.056622
-
(2014)
Drug Metab. Dispos.
, vol.42
, pp. 963-973
-
-
Metushi, I.G.1
Cai, P.2
Vega, L.3
Grant, D.M.4
Uetrecht, J.5
-
13
-
-
0032419597
-
Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection
-
Pollard, R. B., Robinson, P., and Dransfield, K. (1998) Safety profile of nevirapine, a nonnucleoside reverse transcriptase inhibitor for the treatment of human immunodeficiency virus infection Clin. Ther. 20, 1071-1092 10.1016/S0149-2918(98)80105-7
-
(1998)
Clin. Ther.
, vol.20
, pp. 1071-1092
-
-
Pollard, R.B.1
Robinson, P.2
Dransfield, K.3
-
14
-
-
37349023127
-
Case-control exploration of relationships between early rash or liver toxicity and plasma concentrations of nevirapine and primary metabolites
-
Hall, D. B. and MacGregor, T. R. (2007) Case-control exploration of relationships between early rash or liver toxicity and plasma concentrations of nevirapine and primary metabolites HIV Clin. Trials 8, 391-399 10.1310/hct0806-391
-
(2007)
HIV Clin. Trials
, vol.8
, pp. 391-399
-
-
Hall, D.B.1
MacGregor, T.R.2
-
15
-
-
0141681334
-
A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients
-
Stern, J. O., Robinson, P. A., Love, J., Lanes, S., Imperiale, M. S., and Mayers, D. L. (2003) A comprehensive hepatic safety analysis of nevirapine in different populations of HIV infected patients JAIDS, J. Acquired Immune Defic. Syndr. 34, S21-33 10.1097/00126334-200309011-00005
-
(2003)
JAIDS, J. Acquired Immune Defic. Syndr.
, vol.34
, pp. S21-33
-
-
Stern, J.O.1
Robinson, P.A.2
Love, J.3
Lanes, S.4
Imperiale, M.S.5
Mayers, D.L.6
-
16
-
-
84865211587
-
Bioactivation of nevirapine to a reactive quinone methide: Implications for liver injury
-
Sharma, A. M., Li, Y., Novalen, M., Hayes, M. A., and Uetrecht, J. (2012) Bioactivation of nevirapine to a reactive quinone methide: implications for liver injury Chem. Res. Toxicol. 25, 1708-1719 10.1021/tx300172s
-
(2012)
Chem. Res. Toxicol.
, vol.25
, pp. 1708-1719
-
-
Sharma, A.M.1
Li, Y.2
Novalen, M.3
Hayes, M.A.4
Uetrecht, J.5
-
17
-
-
84869479030
-
Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: Humans are more like mice than rats
-
Metushi, I. G., Nakagawa, T., and Uetrecht, J. (2012) Direct oxidation and covalent binding of isoniazid to rodent liver and human hepatic microsomes: humans are more like mice than rats Chem. Res. Toxicol. 25, 2567-2576 10.1021/tx300341r
-
(2012)
Chem. Res. Toxicol.
, vol.25
, pp. 2567-2576
-
-
Metushi, I.G.1
Nakagawa, T.2
Uetrecht, J.3
-
18
-
-
84938892839
-
Immunization with amodiaquine-modified hepatic proteins prevents amodiaquine-induced liver injury
-
Mak, A. and Uetrecht, J. (2015) Immunization with amodiaquine-modified hepatic proteins prevents amodiaquine-induced liver injury J. Immunotoxicol. 12, 361-367 10.3109/1547691X.2014.983660
-
(2015)
J. Immunotoxicol.
, vol.12
, pp. 361-367
-
-
Mak, A.1
Uetrecht, J.2
-
19
-
-
84939237402
-
The Role of CD8 T cells in Amodiaquine-Induced Liver Injury in PD1-/- Mice Cotreated with Anti-CTLA-4
-
Mak, A. and Uetrecht, J. (2015) The Role of CD8 T cells in Amodiaquine-Induced Liver Injury in PD1-/- Mice Cotreated with Anti-CTLA-4 Chem. Res. Toxicol. 28, 1567-1573 10.1021/acs.chemrestox.5b00137
-
(2015)
Chem. Res. Toxicol.
, vol.28
, pp. 1567-1573
-
-
Mak, A.1
Uetrecht, J.2
-
20
-
-
84928604507
-
Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset
-
Metushi, I. G., Cai, P., Dervovic, D., Liu, F., Lobach, A., Nakagawa, T., and Uetrecht, J. (2015) Development of a novel mouse model of amodiaquine-induced liver injury with a delayed onset J. Immunotoxicol. 12, 247-260 10.3109/1547691X.2014.934977
-
(2015)
J. Immunotoxicol.
, vol.12
, pp. 247-260
-
-
Metushi, I.G.1
Cai, P.2
Dervovic, D.3
Liu, F.4
Lobach, A.5
Nakagawa, T.6
Uetrecht, J.7
-
21
-
-
77957932965
-
Type 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver
-
Cripps, J. G., Wang, J., Maria, A., Blumenthal, I., and Gorham, J. D. (2010) Type 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver Hepatology 52, 1350-1359 10.1002/hep.23841
-
(2010)
Hepatology
, vol.52
, pp. 1350-1359
-
-
Cripps, J.G.1
Wang, J.2
Maria, A.3
Blumenthal, I.4
Gorham, J.D.5
-
22
-
-
58849115337
-
Hepatic IL-17 responses in human and murine primary biliary cirrhosis
-
Lan, R. Y., Salunga, T. L., Tsuneyama, K., Lian, Z. X., Yang, G. X., Hsu, W., Moritoki, Y., Ansari, A. A., Kemper, C., Price, J., Atkinson, J. P., Coppel, R. L., and Gershwin, M. E. (2009) Hepatic IL-17 responses in human and murine primary biliary cirrhosis J. Autoimmun. 32, 43-51 10.1016/j.jaut.2008.11.001
-
(2009)
J. Autoimmun.
, vol.32
, pp. 43-51
-
-
Lan, R.Y.1
Salunga, T.L.2
Tsuneyama, K.3
Lian, Z.X.4
Yang, G.X.5
Hsu, W.6
Moritoki, Y.7
Ansari, A.A.8
Kemper, C.9
Price, J.10
Atkinson, J.P.11
Coppel, R.L.12
Gershwin, M.E.13
-
23
-
-
84938058043
-
Drug-induced allergic hepatitis developed in mice when myeloid-derived suppressor cells were depleted prior to halothane treatment
-
Chakraborty, M., Fullerton, A. M., Semple, K., Chea, L. S., Proctor, W. R., Bourdi, M., Kleiner, D. E., Zeng, X., Ryan, P. M., Dagur, P. K., Berkson, J. D., Reilly, T. P., and Pohl, L. R. (2015) Drug-induced allergic hepatitis developed in mice when myeloid-derived suppressor cells were depleted prior to halothane treatment Hepatology 62, 546-557 10.1002/hep.27764
-
(2015)
Hepatology
, vol.62
, pp. 546-557
-
-
Chakraborty, M.1
Fullerton, A.M.2
Semple, K.3
Chea, L.S.4
Proctor, W.R.5
Bourdi, M.6
Kleiner, D.E.7
Zeng, X.8
Ryan, P.M.9
Dagur, P.K.10
Berkson, J.D.11
Reilly, T.P.12
Pohl, L.R.13
|