Subtoxic Concentrations of Hepatotoxic Drugs Lead to Kupffer Cell Activation in a Human in Vitro Liver Model: An Approach to Study Dili

Mediators of Inflammation

Volumn 2015, Issue , 2015, Pages

  Kegel, Victoria ^a   Pfeiffer, Elisa ^a   Burkhardt, Britta ^b   Liu, Jia L ^a   Zeilinger, Katrin ^a   Nüssler, Andreas K ^b   Seehofer, Daniel ^a   Damm, Georg ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ASCORBIC ACID; CD68 ANTIGEN; DICLOFENAC; INTERLEUKIN 10; INTERLEUKIN 6; PARACETAMOL; PROSTAGLANDIN E2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ARTICLE; CELL ACTIVITY; CELL VIABILITY; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KUPFFER CELL; LIVER CELL; MACROPHAGE ACTIVATION; MALE; MIDDLE AGED; OXIDATIVE STRESS; PATHOGENESIS; PHAGOCYTOSIS; SUPERNATANT; TOXIC HEPATITIS; VERY ELDERLY; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE MICROSCOPY; IMMUNE SYSTEM; INJURIES; LIVER; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ACETAMINOPHEN; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL SURVIVAL; CYTOKINES; DICLOFENAC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEPATOCYTES; HUMANS; IMMUNE SYSTEM; KUPFFER CELLS; LIVER; MALE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84944224095     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/640631     Document Type: Article

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