Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Circulation

Volumn 135, Issue 24, 2017, Pages 2373-2388

  Dale, Caroline E ^a   Fatemifar, Ghazaleh ^b   Palmer, Tom M ^a   White, Jon ^a   Prieto Merino, David ^a   Zabaneh, Delilah ^c   Engmann, Jorgen E L ^d   Shah, Tina ^a   Wong, Andrew ^a   Warren, Helen R ^c   McLachlan, Stela ^a   Trompet, Stella ^e,f   Moldovan, Max ^e   Morris, Richard W ^a   Sofat, Reecha ^g   Kumari, Meena ^h   Hyppönen, Elina ^k   Jefferis, Barbara J ⁱ   Gaunt, Tom R ^g   Ben Shlomo, Yoav ^g,j   Zhou, Ang ^a   Gentry Maharaj, Aleksandra ^k   Ryan, Andy ^l   Mutsert, Renée De ^a   Noordam, Raymond ^m   Caulfield, Mark J ^b   Jukema, J Wouter ^b   Worrall, Bradford B ^r   Munroe, Patricia B ^j   Menon, Usha ^a,u   Power, Chris ^g   Kuh, Diana ^g   Lawlor, Debbie A ⁿ   Humphries, Steve E ^a   Mook Kanamori, Dennis O ^a,s   Sattar, Naveed ^e,t   Kivimaki, Mika ^o   Price, Jacqueline F ^g   Davey Smith, George ^p   Dudbridge, Frank ^b   Hingorani, Aroon D ^a   Holmes, Michael V ^q   Casas, Juan P ^a,r   more..

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LANCASTER UNIVERSITY   (United Kingdom)

^c CATHOLIC UNIVERSITY OF MURCIA   (Spain)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^f UNIVERSITY OF EDINBURGH   (United Kingdom)

^g LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^h SOUTH AUSTRALIAN HEALTH AND MEDICAL RESEARCH INSTITUTE   (Australia)

ⁱ EMBL Australia   (Australia)

^j UNIVERSITY OF BRISTOL   (United Kingdom)

^k UNIVERSITY OF ESSEX   (United Kingdom)

^l UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^m UNIVERSITY COLLEGE LONDON   (United Kingdom)

ⁿ INTERUNIVERSITY CARDIOLOGY INSTITUTE OF THE NETHERLANDS   (Netherlands)

^o UNIVERSITY OF VIRGINIA   (United States)

^p UNIVERSITY OF GLASGOW   (United Kingdom)

^q LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^r UNIVERSITY OF LEICESTER   (United Kingdom)

^s UNIVERSITY OF OXFORD   (United Kingdom)

^t UNIVERSITY OF OXFORD   (United Kingdom)

^u NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

more..

Author keywords

adiposity; body fat distribution; body mass index; coronary artery disease; Mendelian randomization analysis; stroke; waist hip ratio

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ARTERIAL WALL THICKNESS; ARTICLE; BODY FAT; BODY MASS; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; DISEASE ASSOCIATION; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENOTYPE; HEART LEFT VENTRICLE HYPERTROPHY; HUMAN; ISCHEMIC HEART DISEASE; MENDELIAN RANDOMIZATION ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PLEIOTROPY; PR INTERVAL; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WAIST HIP RATIO; BODY FAT DISTRIBUTION; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; GENETICS; LONGITUDINAL STUDY; OBSERVATIONAL STUDY; PROCEDURES; PROSPECTIVE STUDY; STROKE;

ADIPOSITY; BODY FAT DISTRIBUTION; CORONARY DISEASE; DIABETES MELLITUS, TYPE 2; HUMANS; LONGITUDINAL STUDIES; MENDELIAN RANDOMIZATION ANALYSIS; OBSERVATIONAL STUDIES AS TOPIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; STROKE;

EID: 85020720920     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.026560     Document Type: Article

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