-
1
-
-
75149194057
-
Update on gout: new therapeutic strategies and options
-
Terkeltaub RA Update on gout: new therapeutic strategies and options. Nat Rev Rheumatol 2010, 6:30-38.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 30-38
-
-
Terkeltaub, R.A.1
-
2
-
-
79952797990
-
Multiple genetic loci influence serum urate and their relationship with gout and cardiovascular disease risk factors
-
Yang Q, Köttgen A, Dehghan A, et al. Multiple genetic loci influence serum urate and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet 2010, 3:523-530.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, pp. 523-530
-
-
Yang, Q.1
Köttgen, A.2
Dehghan, A.3
-
3
-
-
6544243683
-
The cardiovascular and renal relations and manifestations of gout
-
Davis N The cardiovascular and renal relations and manifestations of gout. JAMA 1897, 29:261-262.
-
(1897)
JAMA
, vol.29
, pp. 261-262
-
-
Davis, N.1
-
4
-
-
18244367869
-
Serum uric acid and coronary heart disease in 9,458 incident cases and 155,084 controls: prospective study and meta-Analysis
-
Wheeler JG, Juzwishin DM, Eriksdottir G, Gudnason V, Danesh J Serum uric acid and coronary heart disease in 9,458 incident cases and 155,084 controls: prospective study and meta-Analysis. PLoS Med 2005, 2:236-243.
-
(2005)
PLoS Med
, vol.2
, pp. 236-243
-
-
Wheeler, J.G.1
Juzwishin, D.M.2
Eriksdottir, G.3
Gudnason, V.4
Danesh, J.5
-
5
-
-
33845533406
-
Uric acid restores endothelial function in patients with type 1 diabetes and regular smokers
-
Waring WS, McKnight JA, Webb DJ, Maxwell SRJ Uric acid restores endothelial function in patients with type 1 diabetes and regular smokers. Diabetes 2006, 55:3127-3132.
-
(2006)
Diabetes
, vol.55
, pp. 3127-3132
-
-
Waring, W.S.1
McKnight, J.A.2
Webb, D.J.3
Maxwell, S.R.J.4
-
6
-
-
38148998838
-
Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system
-
Cory DB, Eslami P, Yamamoto K, Nyby MD, Makino H, Tuck ML Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system. J Hypertens 2008, 26:269-275.
-
(2008)
J Hypertens
, vol.26
, pp. 269-275
-
-
Cory, D.B.1
Eslami, P.2
Yamamoto, K.3
Nyby, M.D.4
Makino, H.5
Tuck, M.L.6
-
7
-
-
80051616824
-
Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris
-
Rajendra NS, Ireland S, George J, Belch JJF, Lang CC, Struthers AD Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris. J Am Coll Cardiol 2011, 58:821-828.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 821-828
-
-
Rajendra, N.S.1
Ireland, S.2
George, J.3
Belch, J.J.F.4
Lang, C.C.5
Struthers, A.D.6
-
8
-
-
0037047080
-
Allopurinol and endothelial function in heart failure: future or fantasy?
-
Landmesser U, Drexler H Allopurinol and endothelial function in heart failure: future or fantasy?. Circulation 2002, 106:173-175.
-
(2002)
Circulation
, vol.106
, pp. 173-175
-
-
Landmesser, U.1
Drexler, H.2
-
9
-
-
84867915529
-
Allopurinol: novel indications in cardiovascular disease
-
Struthers A, Shearer F Allopurinol: novel indications in cardiovascular disease. Heart 2012, 98:1543-1545.
-
(2012)
Heart
, vol.98
, pp. 1543-1545
-
-
Struthers, A.1
Shearer, F.2
-
10
-
-
80051657256
-
Allopurinol: a new anti-ischemic role for an old drug
-
Stone PH Allopurinol: a new anti-ischemic role for an old drug. JACC 2001, 58:829-830.
-
(2001)
JACC
, vol.58
, pp. 829-830
-
-
Stone, P.H.1
-
11
-
-
40849083720
-
Mendelian randomisation: using genes as instruments for making causal inferences in epidemiology
-
Lawlor DA, Harbrod RM, Sterne JAC, Timpson N, Davey Smith G Mendelian randomisation: using genes as instruments for making causal inferences in epidemiology. Stat Med 2008, 27:1133-1163.
-
(2008)
Stat Med
, vol.27
, pp. 1133-1163
-
-
Lawlor, D.A.1
Harbrod, R.M.2
Sterne, J.A.C.3
Timpson, N.4
Davey Smith, G.5
-
12
-
-
84927955106
-
Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects
-
Burgess S, Dudbridge F, Thompson SG Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects. Am J Epidemiol 2015, 81:290-291.
-
(2015)
Am J Epidemiol
, vol.81
, pp. 290-291
-
-
Burgess, S.1
Dudbridge, F.2
Thompson, S.G.3
-
13
-
-
84936755918
-
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
-
Bowden J, Davey Smith G, Burgess S Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol 2015, 44:512-525.
-
(2015)
Int J Epidemiol
, vol.44
, pp. 512-525
-
-
Bowden, J.1
Davey Smith, G.2
Burgess, S.3
-
14
-
-
84861827079
-
Using multiple genetic variants as instrumental variables for modifiable risk factors
-
Palmer TM, Lawlor DA, Harbord RM, et al. Using multiple genetic variants as instrumental variables for modifiable risk factors. Stat Met Med Res 2011, 21:223-242.
-
(2011)
Stat Met Med Res
, vol.21
, pp. 223-242
-
-
Palmer, T.M.1
Lawlor, D.A.2
Harbord, R.M.3
-
15
-
-
84882672302
-
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium
-
Shah T, Engmann J, Dale C, et al. Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One 2013, 8:e71345.
-
(2013)
PLoS One
, vol.8
, pp. e71345
-
-
Shah, T.1
Engmann, J.2
Dale, C.3
-
16
-
-
84922391835
-
Association of uric acid genetic risk score with blood pressure: the Rotterdam study
-
Sedaghat S, Pazoki R, Uitterlinden AG, et al. Association of uric acid genetic risk score with blood pressure: the Rotterdam study. Hypertension 2014, 64:1061-1066.
-
(2014)
Hypertension
, vol.64
, pp. 1061-1066
-
-
Sedaghat, S.1
Pazoki, R.2
Uitterlinden, A.G.3
-
18
-
-
84922371409
-
The Ensembl REST API: Ensembl data for any language
-
Yates A, Beal K, Keenan S, et al. The Ensembl REST API: Ensembl data for any language. Bioinformatics 2015, 31:143-145.
-
(2015)
Bioinformatics
, vol.31
, pp. 143-145
-
-
Yates, A.1
Beal, K.2
Keenan, S.3
-
19
-
-
66449084442
-
Infrastructure for the life sciences: design and implementation of the UniProt website
-
Jain E, Bairoch A, Duvaud S, et al. Infrastructure for the life sciences: design and implementation of the UniProt website. BMC Bioinformatics 2009, 10:136.
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 136
-
-
Jain, E.1
Bairoch, A.2
Duvaud, S.3
-
20
-
-
84886426512
-
Calculating statistical power in Mendelian randomization studies
-
Brion MJ, Shakhbazov K, Visscher PM Calculating statistical power in Mendelian randomization studies. Int J Epidemiol 2013, 42:1497-1501.
-
(2013)
Int J Epidemiol
, vol.42
, pp. 1497-1501
-
-
Brion, M.J.1
Shakhbazov, K.2
Visscher, P.M.3
-
21
-
-
84893026568
-
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. discovery of a novel tool compound for in vivo proof-of-concept
-
Ashton KS, Andrews KL, Bryan MC, et al. Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. discovery of a novel tool compound for in vivo proof-of-concept. J Med Chem 2014, 57:309-324.
-
(2014)
J Med Chem
, vol.57
, pp. 309-324
-
-
Ashton, K.S.1
Andrews, K.L.2
Bryan, M.C.3
-
22
-
-
84881442965
-
Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
-
Palmer TM, Nordestgaard BG, Benn M, et al. Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts. BMJ 2013, 347:f4262.
-
(2013)
BMJ
, vol.347
, pp. f4262
-
-
Palmer, T.M.1
Nordestgaard, B.G.2
Benn, M.3
-
23
-
-
84941971658
-
Uric acid and cardiovascular events: a Mendelian randomisation study
-
Kleber ME, Delgado G, Grammer TB, et al. Uric acid and cardiovascular events: a Mendelian randomisation study. J Am Soc Nephrol 2015, 26:2831-2838.
-
(2015)
J Am Soc Nephrol
, vol.26
, pp. 2831-2838
-
-
Kleber, M.E.1
Delgado, G.2
Grammer, T.B.3
-
24
-
-
84857114575
-
Genotype-based changes in serum uric acid affect blood pressure
-
Parsa A, Brown E, Weir MR, Fink JC, Shuldiner AR, Mitchell BD, McArdle PF Genotype-based changes in serum uric acid affect blood pressure. Kidney Int 2012, 81:502-507.
-
(2012)
Kidney Int
, vol.81
, pp. 502-507
-
-
Parsa, A.1
Brown, E.2
Weir, M.R.3
Fink, J.C.4
Shuldiner, A.R.5
Mitchell, B.D.6
McArdle, P.F.7
-
25
-
-
0033567222
-
Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies
-
Clarke R, Shipley M, Lewington S, Youngman L, Collins R, Marmot M, Peto R Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Am J Epidemiol 1999, 150:341-353.
-
(1999)
Am J Epidemiol
, vol.150
, pp. 341-353
-
-
Clarke, R.1
Shipley, M.2
Lewington, S.3
Youngman, L.4
Collins, R.5
Marmot, M.6
Peto, R.7
-
26
-
-
84859215358
-
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
-
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012, 379:1214-1224. Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium.
-
(2012)
Lancet
, vol.379
, pp. 1214-1224
-
-
-
27
-
-
84888256840
-
2-IIA and cardiovascular disease: a Mendelian randomization study
-
2-IIA and cardiovascular disease: a Mendelian randomization study. J Am Coll Cardiol 2013, 62:1966-1976.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. 1966-1976
-
-
Holmes, M.V.1
Simon, T.2
Exeter, H.J.3
-
28
-
-
84891762026
-
The ChEMBL bioactivity database: an update
-
Bento AP, Gaulton A, Hersey A, et al. The ChEMBL bioactivity database: an update. Nucleic Acids Res 2014, 42:1083-1090.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 1083-1090
-
-
Bento, A.P.1
Gaulton, A.2
Hersey, A.3
|