Metabolic basis to sherpa altitude adaptation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 24, 2017, Pages 6382-6387

  Horscroft, James A ^a   Kotwica, Aleksandra O ^a   Laner, Verena ^b   West, James A ^a   Hennis, Philip J ^c   Levett, Denny Z H ^c   Howard, David J ^c   Fernandez, Bernadette O ^d   Burgess, Sarah L ^a   Ament, Zsuzsanna ^a   Gilbert Kawai, Edward T ^c   Vercueil, André ^c   Landis, Blaine D ^e   Mitchell, Kay ^c   Mythen, Monty G ^c   Branco, Cristina ^a   Johnson, Randall S ^a   Feelisch, Martin ^d,f   Montgomery, Hugh E ^c   Griffin, Julian L ^a   Grocott, Michael P W ^c,d,f,g   Gnaiger, Erich ^f,h   Martin, Daniel S ^c   Murray, Andrew J ^a   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b High Resolution Respirometry   (Austria)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^g UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^h INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Altitude; Hypoxia; Metabolism; Mitochondria; Skeletal muscle

Indexed keywords

FATTY ACID; OXYGEN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; GLUCOSE; NITRIC OXIDE;

ALTITUDE; ALTITUDE ACCLIMATIZATION; ARTICLE; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY TRANSFER; ETHNIC GROUP; EVOLUTION; FATTY ACID OXIDATION; GENETIC DIFFERENCE; GENETIC SELECTION; GENETIC VARIABILITY; HUMAN; HYPOBARISM; HYPOXIA; METABOLISM; MUSCLE BIOPSY; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SHERPA (PEOPLE); SKELETAL MUSCLE; TIBETAN (PEOPLE); ADAPTATION; ADULT; ATMOSPHERIC PRESSURE; BLOOD; ENERGY METABOLISM; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENETICS; GLYCOLYSIS; MALE; MUSCLE MITOCHONDRION; NEPAL; OXIDATIVE PHOSPHORYLATION; PATHOPHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; TIBET;

ADAPTATION, PHYSIOLOGICAL; ADULT; ALTITUDE; ATMOSPHERIC PRESSURE; CITRIC ACID CYCLE; ENERGY METABOLISM; ETHNIC GROUPS; FATTY ACIDS; FEMALE; GENE FREQUENCY; GLUCOSE; GLYCOLYSIS; HUMANS; HYPOXIA; MALE; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; NEPAL; NITRIC OXIDE; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PPAR ALPHA; TIBET;

EID: 85020710030     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1700527114     Document Type: Article

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