-
1
-
-
33747596652
-
Oxygen sensing by mitochondria at complex III: The paradox of increased reactive oxygen species during hypoxia
-
PMID: 16857720
-
Guzy RD, SchumackerPT (2006) Oxygen sensing by mitochondria at complex III: the paradox of increased reactive oxygen species during hypoxia. Exp Physiol 91: 807-819. PMID: 16857720
-
(2006)
Exp Physiol
, vol.91
, pp. 807-819
-
-
Guzy, R.D.1
Schumacker, P.T.2
-
2
-
-
33746866371
-
Mitochondrial oxidative stress and heart failure
-
PMID: 16880705
-
Tsutsui H (2006) Mitochondrial oxidative stress and heart failure. Intern Med 45: 809-813. PMID: 16880705
-
(2006)
Intern Med
, vol.45
, pp. 809-813
-
-
Tsutsui, H.1
-
4
-
-
79957440998
-
The hypoxia-associated factor switches cells from HIF-1alpha-to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion
-
PMID: 21512133
-
Koh MY, Lemos R Jr, Liu X, Powis G (2011) The hypoxia-associated factor switches cells from HIF-1alpha-to HIF-2alpha-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion. Cancer Res 71: 4015-4027. doi: 10.1158/0008-5472.CAN-10-4142 PMID: 21512133
-
(2011)
Cancer Res
, vol.71
, pp. 4015-4027
-
-
Koh, M.Y.1
Lemos, Jr.R.2
Liu, X.3
Powis, G.4
-
5
-
-
36049028935
-
HIF-1alpha in endurance training: Suppression of oxidative metabolism
-
PMID: 17855495
-
Mason SD, Rundqvist H, Papandreou I, Duh R, McNulty WJ, et al. (2007) HIF-1alpha in endurance training: suppression of oxidative metabolism. Am J Physiol Regul Integr Comp Physiol 293: R2059-2069. PMID: 17855495
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
, pp. R2059-2069
-
-
Mason, S.D.1
Rundqvist, H.2
Papandreou, I.3
Duh, R.4
McNulty, W.J.5
-
6
-
-
60549087508
-
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells
-
PMID: 19179292
-
O'Hagan KA, Cocchiglia S, Zhdanov AV, Tambuwala MM, Cummins EP, et al. (2009) PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells. Proc Natl Acad Sci USA 106: 2188-2193. doi: 10.1073/pnas.0808801106 PMID: 19179292
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2188-2193
-
-
O'Hagan, K.A.1
Cocchiglia, S.2
Zhdanov, A.V.3
Tambuwala, M.M.4
Cummins, E.P.5
-
7
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
PMID:18281291
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, et al. (2008) Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem 283:10892-10903. doi: 10. 1074/jbc.M800102200 PMID: 18281291
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
-
8
-
-
0035877163
-
Hypoxia-inducible factor 1-mediated inhibition of peroxisome prolifera-tor-activated receptor alpha expression during hypoxia
-
PMID: 11390509
-
Narravula S, Colgan SP (2001) Hypoxia-inducible factor 1-mediated inhibition of peroxisome prolifera-tor-activated receptor alpha expression during hypoxia. J Immunol 166: 7543-7548. PMID: 11390509
-
(2001)
J Immunol
, vol.166
, pp. 7543-7548
-
-
Narravula, S.1
Colgan, S.P.2
-
9
-
-
35649023152
-
Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor alpha/retinoid X receptor
-
PMID: 17963722
-
Belanger AJ, Luo Z, Vincent KA, Akita GY, Cheng SH, et al. (2007) Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor alpha/retinoid X receptor. Biochem Biophys Res Commun 364: 567-572. PMID: 17963722
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 567-572
-
-
Belanger, A.J.1
Luo, Z.2
Vincent, K.A.3
Akita, G.Y.4
Cheng, S.H.5
-
10
-
-
80052685838
-
Normobaric hypoxia impairs human cardiac energetics
-
PMID: 21646398
-
Holloway C, Cochlin L, Codreanu I, Bloch E, Fatemian M, et al. (2011) Normobaric hypoxia impairs human cardiac energetics. FASEBJ 25: 3130-3135. doi: 10.1096/fj.11-183426 PMID: 21646398
-
(2011)
FASEBJ
, vol.25
, pp. 3130-3135
-
-
Holloway, C.1
Cochlin, L.2
Codreanu, I.3
Bloch, E.4
Fatemian, M.5
-
11
-
-
79551649357
-
Cardiac response to hypobaric hypoxia: Persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt
-
PMID: 20978235
-
Holloway CJ, Montgomery HE, Murray AJ, Cochlin LE, Codreanu I, et al. (2011)Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp. FASEB J 25: 792-796. doi: 10.1096/fj.10-172999 PMID: 20978235
-
(2011)
Everest Base Camp. FASEB J
, vol.25
, pp. 792-796
-
-
Holloway, C.J.1
Montgomery, H.E.2
Murray, A.J.3
Cochlin, L.E.4
Codreanu, I.5
-
12
-
-
84860115461
-
Metabolic adaptation to chronic hypoxia in cardiac mitochondria
-
PMID: 22538979
-
Heather LC, Cole MA, Tan JJ, Ambrose LJ, Pope S, et al. (2012) Metabolic adaptation to chronic hypoxia in cardiac mitochondria. Basic Res Cardiol 107: 268. doi: 10.1007/s00395-012-0268-2 PMID: 22538979
-
(2012)
Basic Res Cardiol
, vol.107
, pp. 268
-
-
Heather, L.C.1
Cole, M.A.2
Tan, J.J.3
Ambrose, L.J.4
Pope, S.5
-
13
-
-
84921732687
-
Dietary nitrate increases arginine availability and protects mitochondrial complex i and energetics in the hypoxic rat heart
-
PMID: 25172947
-
Ashmore T, Fernandez BO, Branco-Price C, West JA, Cowburn AS, et al. (2014) Dietary nitrate increases arginine availability and protects mitochondrial complex I and energetics in the hypoxic rat heart. J Physiol 592: 4715-4731. doi: 10.1113/jphysiol.2014.275263 PMID: 25172947
-
(2014)
J Physiol
, vol.592
, pp. 4715-4731
-
-
Ashmore, T.1
Fernandez, B.O.2
Branco-Price, C.3
West, J.A.4
Cowburn, A.S.5
-
14
-
-
0347635416
-
Hypoxia-induceddecrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling
-
PMID: 14733944
-
Essop MF, Razeghi P, McLeod C, Young ME, Taegtmeyer H, et al. (2004) Hypoxia-induceddecrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling. Biochem Biophys Res Commun 314:561-564. PMID: 14733944
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 561-564
-
-
Essop, M.F.1
Razeghi, P.2
McLeod, C.3
Young, M.E.4
Taegtmeyer, H.5
-
15
-
-
26444480274
-
Acclimatization to chronic hypo-baric hypoxia is associated with a differential transcriptional profile between the right and left ventricle
-
PMID: 16180091
-
Adrogue JV, Sharma S, Ngumbela K, Essop MF, Taegtmeyer H (2005) Acclimatization to chronic hypo-baric hypoxia is associated with a differential transcriptional profile between the right and left ventricle. Mol Cell Biochem 278: 71-78. PMID: 16180091
-
(2005)
Mol Cell Biochem
, vol.278
, pp. 71-78
-
-
Adrogue, J.V.1
Sharma, S.2
Ngumbela, K.3
Essop, M.F.4
Taegtmeyer, H.5
-
16
-
-
35648950424
-
Cardiac metabolic adaptations in response to chronic hypoxia
-
PMID: 17761770
-
Essop MF (2007) Cardiac metabolic adaptations in response to chronic hypoxia. J Physiol 584:715-726. PMID: 17761770
-
(2007)
J Physiol
, vol.584
, pp. 715-726
-
-
Essop, M.F.1
-
17
-
-
84883374521
-
Tissue-specific changes in fatty acid oxidation in hypoxic heart and skeletal muscle
-
PMID: 23785078
-
Morash AJ, Kotwica AO, Murray AJ (2013) Tissue-specific changes in fatty acid oxidation in hypoxic heart and skeletal muscle. Am J Physiol Regul Integr Comp Physiol 305: R534-541. doi: 10.1152/ajpregu.00510.2012 PMID: 23785078
-
(2013)
Am J Physiol Regul Integr Comp Physiol
, vol.305
, pp. R534-541
-
-
Morash, A.J.1
Kotwica, A.O.2
Murray, A.J.3
-
18
-
-
84937515801
-
Skeletal muscle energy metabolism in environmental hypoxia: Climbing towards consensus
-
PMID: 25473486
-
Horscroft JA, Murray AJ (2014) Skeletal muscle energy metabolism in environmental hypoxia: climbing towards consensus. Extrem Physiol Med 3:19. doi: 10.1186/2046-7648-3-19 PMID: 25473486
-
(2014)
Extrem Physiol Med
, vol.3
, pp. 19
-
-
Horscroft, J.A.1
Murray, A.J.2
-
19
-
-
84872171601
-
Mitochondrial function in human skeletal muscle following high-altitude exposure
-
PMID: 22636256
-
Jacobs RA, Boushel R, Wright-Paradis C, Calbet JA, Robach P, et al. (2013) Mitochondrial function in human skeletal muscle following high-altitude exposure. Exp Physiol 98: 245-255. doi: 10.1113/expphysiol.2012.066092 PMID: 22636256
-
(2013)
Exp Physiol
, vol.98
, pp. 245-255
-
-
Jacobs, R.A.1
Boushel, R.2
Wright-Paradis, C.3
Calbet, J.A.4
Robach, P.5
-
20
-
-
84870314327
-
Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria
-
PMID: 22968913
-
Jacobs RA, Siebenmann C, Hug M, Toigo M, Meinild AK, et al. (2012) Twenty-eight days at 3454-m altitude diminishes respiratory capacity but enhances efficiency in human skeletal muscle mitochondria. FASEBJ 26: 5192-5200. doi: 10.1096/fj.12-218206 PMID: 22968913
-
(2012)
FASEBJ
, vol.26
, pp. 5192-5200
-
-
Jacobs, R.A.1
Siebenmann, C.2
Hug, M.3
Toigo, M.4
Meinild, A.K.5
-
21
-
-
84860895504
-
Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest
-
PMID: 22186874
-
Levett DZ, Radford EJ, Menassa DA, Graber EF, Morash AJ, et al. (2012) Acclimatization of skeletal muscle mitochondria to high-altitude hypoxia during an ascent of Everest. FASEBJ 26:1431-1441. doi: 10.1096/fj.11-197772 PMID: 22186874
-
(2012)
FASEBJ
, vol.26
, pp. 1431-1441
-
-
Levett, D.Z.1
Radford, E.J.2
Menassa, D.A.3
Graber, E.F.4
Morash, A.J.5
-
22
-
-
0025303926
-
Morphological adaptations of human skeletal muscle to chronic hypoxia
-
PMID: 2323861
-
Hoppeler H, Kleinert E, Schlegel C, Claassen H, Howald H, et al. (1990) Morphological adaptations of human skeletal muscle to chronic hypoxia. Int J Sports Med 11 Suppl 1: S3-9. PMID: 2323861
-
(1990)
Int J Sports Med
, vol.11
, pp. S3-9
-
-
Hoppeler, H.1
Kleinert, E.2
Schlegel, C.3
Claassen, H.4
Howald, H.5
-
23
-
-
0029848113
-
Acclimatization to 4, 300-m altitude decreases reliance on fat as a substrate
-
Roberts AC, Butterfield GE, Cymerman A, Reeves JT, Wolfel EE, et al. (1996) Acclimatization to 4, 300-m altitude decreases reliance on fat as a substrate. J Appl Physiol (1985) 81:1762-1771.
-
(1996)
J Appl Physiol (1985)
, vol.81
, pp. 1762-1771
-
-
Roberts, A.C.1
Butterfield, G.E.2
Cymerman, A.3
Reeves, J.T.4
Wolfel, E.E.5
-
24
-
-
0030032577
-
Altitude and beta-blockade augment glucose utilization during submaximal exercise
-
Roberts AC, Reeves JT, Butterfield GE, Mazzeo RS, Sutton JR, et al. (1996) Altitude and beta-blockade augment glucose utilization during submaximal exercise. J Appl Physiol (1985) 80: 605-615.
-
(1996)
J Appl Physiol (1985)
, vol.80
, pp. 605-615
-
-
Roberts, A.C.1
Reeves, J.T.2
Butterfield, G.E.3
Mazzeo, R.S.4
Sutton, J.R.5
-
25
-
-
44949185670
-
Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells
-
PMID: 18536644
-
Kuznetsov AV, Veksler V, Gellerich FN, Saks V, Margreiter R, et al. (2008) Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells. Nat Protoc 3: 965-976. doi: 10.1038/nprot.2008.61 PMID: 18536644
-
(2008)
Nat Protoc
, vol.3
, pp. 965-976
-
-
Kuznetsov, A.V.1
Veksler, V.2
Gellerich, F.N.3
Saks, V.4
Margreiter, R.5
-
26
-
-
80053643181
-
Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans
-
PMID: 21775647
-
Pesta D, Hoppel F, Macek C, Messner H, Faulhaber M, et al. (2011) Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol 301: R1078-1087. doi: 10.1152/ajpregu.00285.2011 PMID: 21775647
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.301
, pp. R1078-1087
-
-
Pesta, D.1
Hoppel, F.2
Macek, C.3
Messner, H.4
Faulhaber, M.5
-
27
-
-
0033778944
-
Effects of voluntary activity and genetic selection on muscle metabolic capacities in house mice Mus domesticus
-
Houle-Leroy P, Garland T Jr, Swallow JG, Guderley H (2000) Effects of voluntary activity and genetic selection on muscle metabolic capacities in house mice Mus domesticus. J Appl Physiol (1985) 89: 1608-1616.
-
(2000)
J Appl Physiol (1985)
, vol.89
, pp. 1608-1616
-
-
Houle-Leroy, P.1
Garland, Jr.T.2
Swallow, J.G.3
Guderley, H.4
-
28
-
-
14644441769
-
Muscle remodeling in relation to blood supply: Implications for seasonal changes in mitochondrial enzymes
-
PMID: 15671340
-
McClelland GB, Dalziel AC, Fragoso NM, Moyes CD (2005) Muscle remodeling in relation to blood supply: implications for seasonal changes in mitochondrial enzymes. J Exp Biol 208: 515-522. PMID: 15671340
-
(2005)
J Exp Biol
, vol.208
, pp. 515-522
-
-
McClelland, G.B.1
Dalziel, A.C.2
Fragoso, N.M.3
Moyes, C.D.4
-
29
-
-
84864151903
-
Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects
-
PMID: 22586215
-
Larsen S, Nielsen J, Hansen CN, Nielsen LB, Wibrand F, et al. (2012) Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects. J Physiol 590: 3349-3360. doi: 10.1113/jphysiol.2012.230185 PMID: 22586215
-
(2012)
J Physiol
, vol.590
, pp. 3349-3360
-
-
Larsen, S.1
Nielsen, J.2
Hansen, C.N.3
Nielsen, L.B.4
Wibrand, F.5
-
30
-
-
0036095530
-
Changes in MCT1, MCT 4, and LDH expression are tissue specific in rats after long-term hypobaric hypoxia
-
McClelland GB, Brooks GA (2002) Changes in MCT1, MCT 4, and LDH expression are tissue specific in rats after long-term hypobaric hypoxia. J Appl Physiol (1985) 92:1573-1584.
-
(2002)
J Appl Physiol (1985)
, vol.92
, pp. 1573-1584
-
-
McClelland, G.B.1
Brooks, G.A.2
-
31
-
-
0029879790
-
Aerobic capacity and skeletal muscle properties of normoxic and hypoxic rats in response to training
-
PMID: 8596716
-
Abdelmalki A, Fimbel S, Mayet-Sornay MH, Sempore B, FavierR (1996) Aerobic capacity and skeletal muscle properties of normoxic and hypoxic rats in response to training. Pflugers Arch 431: 671-679. PMID: 8596716
-
(1996)
Pflugers Arch
, vol.431
, pp. 671-679
-
-
Abdelmalki, A.1
Fimbel, S.2
Mayet-Sornay, M.H.3
Sempore, B.4
Favier, R.5
-
32
-
-
0025876396
-
Mechanistic stoichiometry of mitochondrial oxidative phosphorylation
-
PMID: 2012815
-
Hinkle PC, Kumar MA, Resetar A, Harris DL (1991) Mechanistic stoichiometry of mitochondrial oxidative phosphorylation. Biochemistry 30: 3576-3582. PMID: 2012815
-
(1991)
Biochemistry
, vol.30
, pp. 3576-3582
-
-
Hinkle, P.C.1
Kumar, M.A.2
Resetar, A.3
Harris, D.L.4
-
33
-
-
58149136865
-
Roles of p53, MYC and HIF-1 in regulating glycolysis-the seventh hallmark of cancer
-
PMID: 18766298
-
Yeung SJ, Pan J, Lee MH (2008) Roles of p53, MYC and HIF-1 in regulating glycolysis-the seventh hallmark of cancer. Cell Mol Life Sci 65: 3981-3999. doi: 10.1007/s00018-008-8224-x PMID: 18766298
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 3981-3999
-
-
Yeung, S.J.1
Pan, J.2
Lee, M.H.3
-
34
-
-
29544450082
-
Acute and severe hypo-baric hypoxia increases oxidative stress and impairs mitochondrial function in mouse skeletal muscle
-
Magalhaes J, Ascensao A, Soares JM, Ferreira R, Neuparth MJ, et al. (2005) Acute and severe hypo-baric hypoxia increases oxidative stress and impairs mitochondrial function in mouse skeletal muscle. J Appl Physiol (1985) 99:1247-1253.
-
(2005)
J Appl Physiol (1985)
, vol.99
, pp. 1247-1253
-
-
Magalhaes, J.1
Ascensao, A.2
Soares, J.M.3
Ferreira, R.4
Neuparth, M.J.5
-
35
-
-
36849067904
-
Vitamin E prevents hypo-baric hypoxia-induced mitochondrial dysfunction in skeletal muscle
-
Magalhaes J, Ferreira R, Neuparth MJ, Oliveira PJ, Marques F, et al. (2007) Vitamin E prevents hypo-baric hypoxia-induced mitochondrial dysfunction in skeletal muscle. Clin Sci (Lond) 113: 459-466.
-
(2007)
Clin Sci (Lond)
, vol.113
, pp. 459-466
-
-
Magalhaes, J.1
Ferreira, R.2
Neuparth, M.J.3
Oliveira, P.J.4
Marques, F.5
-
36
-
-
38149059911
-
Mitochondria and cellular oxygen sensing in the HIF pathway
-
PMID: 18062771
-
Taylor CT (2008) Mitochondria and cellular oxygen sensing in the HIF pathway. Biochem J 409:19-26. PMID: 18062771
-
(2008)
Biochem J
, vol.409
, pp. 19-26
-
-
Taylor, C.T.1
-
37
-
-
84878003949
-
The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress
-
PMID:23597505
-
Anedda A, Lopez-Bernardo E, Acosta-Iborra B, Saadeh Suleiman M, Landazuri MO, et al. (2013) The transcription factor Nrf2 promotes survival by enhancing the expression of uncoupling protein 3 under conditions of oxidative stress. Free Radic Biol Med 61: 395-407. doi: 10.1016/j.freeradbiomed.2013. 04.007 PMID: 23597505
-
(2013)
Free Radic Biol Med
, vol.61
, pp. 395-407
-
-
Anedda, A.1
Lopez-Bernardo, E.2
Acosta-Iborra, B.3
Saadeh Suleiman, M.4
Landazuri, M.O.5
-
38
-
-
84946544768
-
Mitochondrial responses to extreme environments: Insights from metabolomics
-
PMID: 25949809
-
O'Brien KA, Griffin JL, Murray AJ, Edwards LM (2015) Mitochondrial responses to extreme environments: insights from metabolomics. Extrem Physiol Med 4: 7. doi: 10.1186/s 13728-015-0026-9 PMID: 25949809
-
(2015)
Extrem Physiol Med
, vol.4
, pp. 7
-
-
O'Brien, K.A.1
Griffin, J.L.2
Murray, A.J.3
Edwards, L.M.4
|