FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation

Journal of Neuroimmune Pharmacology

Volumn 12, Issue 4, 2017, Pages 670-681

  McManus, Róisín M ^a   Finucane, Orla M ^a   Wilk, Mieszko M ^a   Mills, Kingston H G ^a   Lynch, Marina A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Alzheimer s disease; Amyloid ; Astrocytes; Blood brain barrier permeability; FTY720; Phagocytosis

Indexed keywords

AMYLOID BETA PROTEIN; FINGOLIMOD; AMYLOID PRECURSOR PROTEIN; IMMUNOSUPPRESSIVE AGENT; PRESENILIN 1;

ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; BORDETELLA PERTUSSIS; CELL COUNT; CELL VIABILITY ASSAY; COGNITIVE DEFECT; COLONY FORMING UNIT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENTATE GYRUS; DISEASE PREDISPOSITION; FLOW CYTOMETRY; GENOTYPING TECHNIQUE; GLIAL CELL CULTURE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; INFLAMMATION; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOLOGY; PHAGOCYTOSIS; PHYSIOLOGICAL PROCESS; POST HOC ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TEMPERATURE; AMYLOID PLAQUE; ANIMAL; ASTROCYTE; BORDETELLOSIS; COMPLICATION; DRUG EFFECT; GENETICS; METABOLISM; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ASTROCYTES; BORDETELLA INFECTIONS; BORDETELLA PERTUSSIS; FINGOLIMOD HYDROCHLORIDE; IMMUNOSUPPRESSIVE AGENTS; MICE; MICE, TRANSGENIC; PLAQUE, AMYLOID; PRESENILIN-1;

EID: 85020540681     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-017-9753-6     Document Type: Article

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