High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice

Clinical Science

Volumn 131, Issue 12, 2017, Pages 1261-1281

  Krishna, Smriti Murali ^a   Seto, Sai Wang ^a,b   Jose, Roby ^a   Li, Jiaze ^a   Moxon, Joseph ^a   Clancy, Paula ^a   Crossman, David J ^c   Norman, Paul ^d   Emeto, Theophilus I ^a   Golledge, Jonathan ^a,e  

^a JAMES COOK UNIVERSITY   (Australia)

^b WESTERN SYDNEY UNIVERSITY   (Australia)

^c THE UNIVERSITY OF AUCKLAND   (New Zealand)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e TOWNSVILLE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN; C REACTIVE PROTEIN; CHLORDANE; COLLAGEN TYPE 3; COLLAGEN TYPE 3A1; CREATININE; DNA NUCLEOTIDYLEXOTRANSFERASE; ELASTIN; GAMMA INTERFERON; GELATINASE B; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HIGH DENSITY LIPOPROTEIN; HOMOCYSTEINE; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; APOLIPOPROTEIN E; BIOLOGICAL MARKER; COL3A1 PROTEIN, HUMAN; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP1 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE; THROMBOSPONDIN-1, HUMAN; THROMBOSPONDIN-1, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ABDOMINAL AORTIC ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; ATHEROSCLEROSIS; AUTOPSY; BLOOD PRESSURE MEASUREMENT; BLOOD SAMPLING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEGRADATION; DISEASE COURSE; ECHOGRAPHY; ENZYMATIC ASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FLOW CYTOMETRY; FOLLOW UP; FROZEN SECTION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; MORPHOMETRY; MOUSE; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; THROMBOCYTE POOR PLASMA; TUNEL ASSAY; VASCULAR SMOOTH MUSCLE CELL; WESTERN BLOTTING; ZYMOGRAPHY; ABDOMINAL AORTA; ANIMAL; AORTIC ANEURYSM, ABDOMINAL; BLOOD; CELL CULTURE; CHEMICALLY INDUCED; DEFICIENCY; DIAGNOSTIC IMAGING; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; METABOLISM; ODDS RATIO; PATHOLOGY; PHENOTYPE; TIME FACTOR; VASCULAR REMODELING;

ANGIOTENSIN II; ANIMALS; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; BIOMARKERS; CELLS, CULTURED; COLLAGEN TYPE III; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELASTIN; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; MICE, KNOCKOUT; ODDS RATIO; PHENOTYPE; PROTEOLYSIS; RECEPTORS, LDL; RISK FACTORS; THROMBOSPONDIN 1; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS; ULTRASONOGRAPHY; VASCULAR REMODELING;

EID: 85020300173     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20160970     Document Type: Article

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