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1
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33751198051
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Abdominal aortic aneurysm: Pathogenesis and implications for management
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DOI 10.1161/01.ATV.0000245819.32762.cb, PII 0004360520061200000006
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Golledge J, Muller J, Daugherty A, Norman P. Abdominal aortic aneurysm: pathogenesis and implications for management. Arterioscler Thromb Vasc Biol 2006; 26:2605-2613. (Pubitemid 44777272)
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Arteriosclerosis, Thrombosis, and Vascular Biology
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Golledge, J.1
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Population Health Division. Sydney: NSW Department of Health. Available at. Accessed 14/12/07
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Population Health Division. The health of the people of New South Wales - Report of the Chief Health Officer. Sydney: NSW Department of Health. Available at: http://www.health.nsw.gov.au/public-health/chorep/cvd/cvd-aa.htm. Accessed 14/12/07.
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The Health of the People of New South Wales - Report of the Chief Health Officer
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3
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National vital statistics reports. Hyattsville, MD: National Center for Health Statistics. Viewed at on 15/9/07
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Miniño A, Heron M, Smith B, Kochanek K. Deaths: final data for1999. National vital statistics reports. Hyattsville, MD: National Center for Health Statistics. Viewed at http://www.cdc.gov/nchs/data/statab/lcwk9.pdf on 15/9/07.
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Deaths: Final Data for1999
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Miniño, A.1
Heron, M.2
Smith, B.3
Kochanek, K.4
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4
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34250726580
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Endovascular aortic aneurysm repair in patients with the highest risk and in-hospital mortality in the United States
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Timaran CH, Veith FJ, Rosero EB, et al. Endovascular aortic aneurysm repair in patients with the highest risk and in-hospital mortality in the United States. Arch Surg 2007; 142:520-524.
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Arch Surg
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Timaran, C.H.1
Veith, F.J.2
Rosero, E.B.3
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5
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33846539200
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The outcome of endovascular repair of small abdominal aortic aneurysms
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Golledge J, Parr A, Boult M, et al. The outcome of endovascular repair of small abdominal aortic aneurysms. Ann Surg 2007; 245:326-333.
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Ann Surg
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Golledge, J.1
Parr, A.2
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6
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84993746135
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Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): Randomised controlled trial
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EVAR trial participants
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EVAR trial participants. Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial. Lancet 2005; 365:2179-2186.
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Lancet
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7
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34548426860
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Lost to follow-up: A potential underappreciated limitation of endovascular aneurysm repair
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Jones WB, Taylor SM, Kalbaugh CA, et al. Lost to follow-up: a potential underappreciated limitation of endovascular aneurysm repair. J Vasc Surg 2007; 46:434-440.
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J Vasc Surg
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Jones, W.B.1
Taylor, S.M.2
Kalbaugh, C.A.3
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8
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38349185886
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Modelling the long-term costeffectiveness of endovascular or open repair for abdominal aortic aneurysm
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Based on data from the EVAR 1 trial endovascular AAA repair was estimated to cost £3800 more per case than open repair
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Epstein DM, Sculpher MJ, Manca A, et al. Modelling the long-term costeffectiveness of endovascular or open repair for abdominal aortic aneurysm. Br J Surg 2008; 95:183-190. Based on data from the EVAR 1 trial endovascular AAA repair was estimated to cost £3800 more per case than open repair.
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(2008)
Br J Surg
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, pp. 183-190
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Epstein, D.M.1
Sculpher, M.J.2
Manca, A.3
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9
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13244286632
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Screening for abdominal aortic aneurysm: A best-evidence systematic review for the US preventive services task force
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Fleming C, Whitlock EP, Bell TL, Lederle FA. Screening for abdominal aortic aneurysm: a best-evidence systematic review for the US Preventive Services Task Force. Ann Int Med 2005; 142:203-211.
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Ann Int Med
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Fleming, C.1
Whitlock, E.P.2
Bell, T.L.3
Lederle, F.A.4
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10
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58149265250
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Circulating markers of abdominal aortic aneurysm presence and progression
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This recent review summarizes currently identified circulating markers associated with AAA presence
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Golledge J, Tsao PS, Dalman RL, Norman PE. Circulating markers of abdominal aortic aneurysm presence and progression. Circulation 2008; 118:2382-2392. This recent review summarizes currently identified circulating markers associated with AAA presence.
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(2008)
Circulation
, vol.118
, pp. 2382-2392
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Golledge, J.1
Tsao, P.S.2
Dalman, R.L.3
Norman, P.E.4
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11
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48049115070
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Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions
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This study suggests a potential mechanism underlying the relative protection from AAA presence and progression in diabetics
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Golledge J, Karan M, Moran CS, et al. Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions. Eur Heart J 2008; 29:665-672. This study suggests a potential mechanism underlying the relative protection from AAA presence and progression in diabetics.
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(2008)
Eur Heart J
, vol.29
, pp. 665-672
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Golledge, J.1
Karan, M.2
Moran, C.S.3
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12
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34548419640
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Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms
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Lenk GM, Tromp G, Weinsheimer S, et al. Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms. BMC Genomics 2007; 8:237.
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(2007)
BMC Genomics
, vol.8
, pp. 237
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Lenk, G.M.1
Tromp, G.2
Weinsheimer, S.3
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13
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59649094037
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Proteomic identification of differentially expressed proteins in aortic wall of patients with ruptured and nonruptured abdominal aortic aneurysms
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This study carries out a proteomic assessment of proteins extracted from biopsies of ruptured and intact AAA. They identified relative up-regulation of peroxiredoxin-2 and down-regulation of vitronectin
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Urbonavicius S, Lindholt JS, Vorum H, et al. Proteomic identification of differentially expressed proteins in aortic wall of patients with ruptured and nonruptured abdominal aortic aneurysms. J Vasc Surg 2009; 49:455-463. This study carries out a proteomic assessment of proteins extracted from biopsies of ruptured and intact AAA. They identified relative up-regulation of peroxiredoxin-2 and down-regulation of vitronectin.
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(2009)
J Vasc Surg
, vol.49
, pp. 455-463
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Urbonavicius, S.1
Lindholt, J.S.2
Vorum, H.3
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14
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38649091662
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The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm
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This is the largest study of a genetic site associated with AAA with replication in multiple cohorts suggesting the association of a site on chromosome 9 with AAA
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Helgadottir A, Thorleifsson G, Magnusson KP, et al. The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nat Genet 2008; 40:217-224. This is the largest study of a genetic site associated with AAA with replication in multiple cohorts suggesting the association of a site on chromosome 9 with AAA.
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(2008)
Nat Genet
, vol.40
, pp. 217-224
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Helgadottir, A.1
Thorleifsson, G.2
Magnusson, K.P.3
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15
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60749104192
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Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have a impact on aneurysmal expansion
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Thompson AR, Golledge J, Cooper AJ, et al. Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have a impact on aneurysmal expansion. Eur J Hum Gen 2009; 17:391-394.
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(2009)
Eur J Hum Gen
, vol.17
, pp. 391-394
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Thompson, A.R.1
Golledge, J.2
Cooper, A.J.3
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16
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38049186595
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Aortic aneurysms: An immune disease with a strong genetic component
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Kuivaniemi H, Platsoucas CD, Tilson MD 3rd. Aortic aneurysms: an immune disease with a strong genetic component. Circulation 2008; 117:242-252.
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(2008)
Circulation
, vol.117
, pp. 242-252
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Kuivaniemi, H.1
Platsoucas, C.D.2
Tilson Iii, M.D.3
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17
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36849084039
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Candidate gene association studies in abdominal aortic aneurysm disease: A review and metaanalysis
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This summary analysis reports an association of genetic polymorphisms in a number of genes including angiotensin-converting enzyme and methyl tetrahydrofolate reductase with AAA
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Thompson AR, Drenos F, Hafez H, Humphries SE. Candidate gene association studies in abdominal aortic aneurysm disease: a review and metaanalysis. Eur J Vasc Endovasc Surg 2008; 35:19-30. This summary analysis reports an association of genetic polymorphisms in a number of genes including angiotensin-converting enzyme and methyl tetrahydrofolate reductase with AAA.
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(2008)
Eur J Vasc Endovasc Surg
, vol.35
, pp. 19-30
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Thompson, A.R.1
Drenos, F.2
Hafez, H.3
Humphries, S.E.4
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18
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51549108089
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Genome wide association studies: Identifying the genes that determine the risk of abdominal aortic aneurysm
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Aneurysm Consortium., This editorial outlines a current Welcome Trust funded genome wide association study for AAA
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Aneurysm Consortium. Genome wide association studies: identifying the genes that determine the risk of abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 2008; 36:395-396. This editorial outlines a current Welcome Trust funded genome wide association study for AAA.
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(2008)
Eur J Vasc Endovasc Surg
, vol.36
, pp. 395-396
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19
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0036582392
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Positron emission tomography (PET) evaluation of abdominal aortic aneurysm (AAA)
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Sakalihasan N, Van Damme H, Gomez P, et al. Positron emission tomography (PET) evaluation of abdominal aortic aneurysm (AAA). Eur J Vasc Endovasc Surg 2002; 23:431-436.
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(2002)
Eur J Vasc Endovasc Surg
, vol.23
, pp. 431-436
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Sakalihasan, N.1
Van Damme, H.2
Gomez, P.3
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20
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3042739940
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Contribution of PET scanning to the evaluation of abdominal aortic aneurysm
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Sakalihasan N, Hustinx R, Limet R. Contribution of PET scanning to the evaluation of abdominal aortic aneurysm. Semin Vasc Surg 2004; 17:144-153.
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(2004)
Semin Vasc Surg
, vol.17
, pp. 144-153
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Sakalihasan, N.1
Hustinx, R.2
Limet, R.3
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21
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47249164675
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Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms
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This study reports the first correlation between FDG uptake and histological changes within human AAA
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Reeps C, Essler M, Pelisek J, et al. Increased 18F-fluorodeoxyglucose uptake in abdominal aortic aneurysms in positron emission/computed tomography is associated with inflammation, aortic wall instability, and acute symptoms. J Vasc Surg 2008; 48:417-423. This study reports the first correlation between FDG uptake and histological changes within human AAA.
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(2008)
J Vasc Surg
, vol.48
, pp. 417-423
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Reeps, C.1
Essler, M.2
Pelisek, J.3
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22
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49449114513
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In vivo imaging of abdominal aortic aneurysms: Increased FDG uptake suggests inflammation in the aneurysm wall
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Truijers M, Kurvers HA, Bredie SJ, et al. In vivo imaging of abdominal aortic aneurysms: increased FDG uptake suggests inflammation in the aneurysm wall. J Endovasc Ther 2008; 15:462-467.
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(2008)
J Endovasc Ther
, vol.15
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Truijers, M.1
Kurvers, H.A.2
Bredie, S.J.3
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23
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33747393705
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99mTc-annexin-V functional imaging of luminal thrombus activity in abdominal aortic aneurysms
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Sarda-Mantel L, Coutard M, Rouzet F, et al. 99mTc-annexin-V functional imaging of luminal thrombus activity in abdominal aortic aneurysms. Arterioscler Thromb Vasc Biol 2006; 26:2153-2159.
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(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 2153-2159
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Sarda-Mantel, L.1
Coutard, M.2
Rouzet, F.3
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24
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0041384102
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Smokers' relative risk for aortic aneurysm compared with other smoking-related diseases: A systematic review
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Lederle FA, Nelson DB, Joseph AM. Smokers' relative risk for aortic aneurysm compared with other smoking-related diseases: a systematic review. J Vasc Surg 2003; 38:329-334.
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(2003)
J Vasc Surg
, vol.38
, pp. 329-334
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Lederle, F.A.1
Nelson, D.B.2
Joseph, A.M.3
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25
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41949095013
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Medical management of small abdominal aortic aneurysms
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Baxter BT, Terrin MC, Dalman RL. Medical management of small abdominal aortic aneurysms. Circulation 2008; 117:1883-1889.
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(2008)
Circulation
, vol.117
, pp. 1883-1889
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Baxter, B.T.1
Terrin, M.C.2
Dalman, R.L.3
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26
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0035488854
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Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: A randomized, double-blind, placebo-controlled pilot study
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Mosorin M, Juvonen J, Biancari F, et al. Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study. J Vasc Surg 2001; 34:606-610.
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(2001)
J Vasc Surg
, vol.34
, pp. 606-610
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Mosorin, M.1
Juvonen, J.2
Biancari, F.3
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27
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0034827044
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Randomized double-blind controlled trial of roxithromycin for prevention of abdominal aortic aneurysm expansion
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Vammen S, Lindholt JS, Ostergaard L, et al. Randomized double-blind controlled trial of roxithromycin for prevention of abdominal aortic aneurysm expansion. Br J Surg 2001; 88:1066-1072.
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(2001)
Br J Surg
, vol.88
, pp. 1066-1072
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Vammen, S.1
Lindholt, J.S.2
Ostergaard, L.3
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28
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49749138519
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A randomized, placebocontrolled trial of doxycycline after endoluminal aneurysm repair
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This is the first medication trial in combination with endovascular AAA repair
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Hackmann AE, Rubin BG, Sanchez LA, et al. A randomized, placebocontrolled trial of doxycycline after endoluminal aneurysm repair. J Vasc Surg 2008; 48:519-526. This is the first medication trial in combination with endovascular AAA repair.
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(2008)
J Vasc Surg
, vol.48
, pp. 519-526
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Hackmann, A.E.1
Rubin, B.G.2
Sanchez, L.A.3
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29
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40749153991
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Effect of statins on proteolytic activity in the wall of abdominal aortic aneurysms
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This study reports reduced MMP-9, cathepsin H and cathepsin L in aortic biopsies from patients receiving statins
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Abisi S, Burnand KG, Humphries J, et al. Effect of statins on proteolytic activity in the wall of abdominal aortic aneurysms. Br J Surg 2008; 95:333-337. This study reports reduced MMP-9, cathepsin H and cathepsin L in aortic biopsies from patients receiving statins.
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(2008)
Br J Surg
, vol.95
, pp. 333-337
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Abisi, S.1
Burnand, K.G.2
Humphries, J.3
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30
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11144276528
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Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice
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Steinmetz EF, Buckley C, Shames ML, et al. Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice. Ann Surg 2005; 241:92-101.
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(2005)
Ann Surg
, vol.241
, pp. 92-101
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Steinmetz, E.F.1
Buckley, C.2
Shames, M.L.3
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31
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30544440956
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Simvastatin suppresses experimental aortic aneurysm expansion
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Kalyanasundaram A, Elmore JR, Manazer JR, et al. Simvastatin suppresses experimental aortic aneurysm expansion. J Vasc Surg 2006; 43:117-124.
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(2006)
J Vasc Surg
, vol.43
, pp. 117-124
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Kalyanasundaram, A.1
Elmore, J.R.2
Manazer, J.R.3
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32
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57649200495
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Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration
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This is the latest of a series of publications suggesting statins reduce AAA formation in rodent models
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Shiraya S, Miyake T, Aoki M, et al. Inhibition of development of experimental aortic abdominal aneurysm in rat model by atorvastatin through inhibition of macrophage migration. Atherosclerosis 2009; 202:34-40. This is the latest of a series of publications suggesting statins reduce AAA formation in rodent models.
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(2009)
Atherosclerosis
, vol.202
, pp. 34-40
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Shiraya, S.1
Miyake, T.2
Aoki, M.3
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33
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31344433148
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Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins
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Sukhija R, Aronow WS, Sandhu R, et al. Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins. Am J Cardiol 2006; 97:279-280.
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(2006)
Am J Cardiol
, vol.97
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Sukhija, R.1
Aronow, W.S.2
Sandhu, R.3
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34
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33744902627
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Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth
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Schouten O, van Laanen JH, Boersma E, et al. Statins are associated with a reduced infrarenal abdominal aortic aneurysm growth. Eur J Vasc Endovasc Surg 2006; 32:21-26.
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(2006)
Eur J Vasc Endovasc Surg
, vol.32
, pp. 21-26
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Schouten, O.1
Van Laanen, J.H.2
Boersma, E.3
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35
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44349115500
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SMART study group. Growth predictors and prognosis of small abdominal aortic aneurysms
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This study is one of three cohort investigations reporting an association between statin prescription and reduced small AAA progression
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Schlösser FJ, TangelderMJ, Verhagen HJ, et al., SMART study group. Growth predictors and prognosis of small abdominal aortic aneurysms. J Vasc Surg 2008; 47:1127-1133. This study is one of three cohort investigations reporting an association between statin prescription and reduced small AAA progression.
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(2008)
J Vasc Surg
, vol.47
, pp. 1127-1133
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Schlösser, F.J.1
Tangelder, M.J.2
Verhagen, H.J.3
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36
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52049104502
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The role of the renin-angiotensin system in aortic aneurysmal diseases
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Lu H, Rateri DL, Cassis LA, Daugherty A. The role of the renin-angiotensin system in aortic aneurysmal diseases. Curr Hypertens Rep 2008; 10:99-106.
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(2008)
Curr Hypertens Rep
, vol.10
, pp. 99-106
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Lu, H.1
Rateri, D.L.2
Cassis, L.A.3
Daugherty, A.4
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37
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0034129997
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Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
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Daugherty A, Manning MW, Cassis LA. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J Clin Invest 2000; 105:1605-1612.
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J Clin Invest
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Daugherty, A.1
Manning, M.W.2
Cassis, L.A.3
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38
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19044382607
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Increased local angiotensin II formation in aneurysmal aorta
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Nishimoto M, Takai S, Fukumoto H, et al. Increased local angiotensin II formation in aneurysmal aorta. Life Sci 2002; 71:2195-2205.
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(2002)
Life Sci
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Nishimoto, M.1
Takai, S.2
Fukumoto, H.3
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39
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0036867198
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Possible roles of angiotensin II-forming enzymes, angiotensin converting enzyme and chymase-like enzyme, in the human aneurysmal aorta
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Tsunemi K, Takai S, Nishimoto M, et al. Possible roles of angiotensin II-forming enzymes, angiotensin converting enzyme and chymase-like enzyme, in the human aneurysmal aorta. Hypertens Res 2002; 25:817-822.
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Hypertens Res
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Tsunemi, K.1
Takai, S.2
Nishimoto, M.3
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40
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42249103284
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Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts
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This study is the first to show association between a genetic polymorphism in angiotensin II type 1 receptor and AAA in three distinct populations
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Jones GT, Thompson AR, van Bockxmeer FM, et al. Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts. Arterioscler Thromb Vasc Biol 2008; 28:764-770. This study is the first to show association between a genetic polymorphism in angiotensin II type 1 receptor and AAA in three distinct populations.
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(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 764-770
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Jones, G.T.1
Thompson, A.R.2
Van Bockxmeer, F.M.3
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41
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0036781239
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An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats
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Nagashima H, Uto K, Sakomura Y, et al. An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. J Vasc Surg 2002; 36:818-823.
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(2002)
J Vasc Surg
, vol.36
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Nagashima, H.1
Uto, K.2
Sakomura, Y.3
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42
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0035348484
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Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors
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Liao S, Miralles M, Kelley BJ, et al. Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors. J Vasc Surg 2001; 33:1057-1064.
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(2001)
J Vasc Surg
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Liao, S.1
Miralles, M.2
Kelley, B.J.3
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43
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59849112584
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Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation
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This study demonstrated that telmisartan inhibits elastase-induced AAA formation in rats
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Kaschina E, Schrader F, Sommerfeld M, et al. Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation. J Hypertens 2008; 26:2361-2373. This study demonstrated that telmisartan inhibits elastase-induced AAA formation in rats.
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(2008)
J Hypertens
, vol.26
, pp. 2361-2373
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Kaschina, E.1
Schrader, F.2
Sommerfeld, M.3
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44
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33747108061
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Angiotensin-converting enzyme inhibitors and aortic rupture: A population-based case-control study
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Hackam DG, Thiruchelvam D, Redelmeier DA. Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study. Lancet 2006; 368:659-665.
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Lancet
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Hackam, D.G.1
Thiruchelvam, D.2
Redelmeier, D.A.3
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45
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34948849376
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Effect of perindopril on large artery stiffness and aortic root diameter in patients with Marfan syndrome: A randomized controlled trial
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Ahimastos AA, Aggarwal A, D'Orsa KM, et al. Effect of perindopril on large artery stiffness and aortic root diameter in patients with Marfan syndrome: a randomized controlled trial. J Am Med Assoc 2007; 298:1539-1547.
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J Am Med Assoc
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Ahimastos, A.A.1
Aggarwal, A.2
D'Orsa, K.M.3
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46
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45949092534
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Angiotensin II blockade and aorticroot dilation in Marfan's syndrome
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Brooke BS, Habashi JP, Judge DP, et al. Angiotensin II blockade and aorticroot dilation in Marfan's syndrome. N Engl J Med 2008; 358:2787-2795.
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N Engl J Med
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