Thrombospondin-1 and CD47 regulate blood pressure and cardiac responses to vasoactive stress

Matrix Biology

Volumn 28, Issue 2, 2009, Pages 110-119

  Isenberg, Jeff S ^a   Qin, Yan ^b   Maxhimer, Justin B ^a   Sipes, John M ^a   Despres, Daryl ^c   Schnermann, Jurgen ^b   Frazier, William A ^d   Roberts, David D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood pressure; Cardiac output; CD47; Nitric oxide; Thrombospondin 1

Indexed keywords

ADRENALIN; CD47 ANTIGEN; ISOFLURANE; NITRIC OXIDE; THROMBOSPONDIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; HEART EJECTION FRACTION; HEART OUTPUT; HEART RATE; HEART STRESS; HYPERTENSION; HYPOTENSION; MOUSE; NERVE BLOCK; NONHUMAN; PRIORITY JOURNAL; PULSE PRESSURE;

ANIMALS; ANTIGENS, CD47; BLOOD PRESSURE; CYCLIC AMP; CYCLIC GMP; ECHOCARDIOGRAPHY; HEART; HEART RATE; IMMUNOASSAY; MICE; MICE, KNOCKOUT; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; SKIN; STRESS, PHYSIOLOGICAL; THROMBOSPONDIN 1;

MUS;

EID: 60749126714     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2009.01.002     Document Type: Article

References (47)

1. Arnal J.F., Dinh-Xuan A.T., Pueyo M., Darblade B., and Rami J. Endothelium-derived nitric oxide and vascular physiology and pathology. Cell. Mol. Life Sci. 55 (1999) 1078-1087
2. Becker D.E., and Haas D.A. Management of complications during moderate and deep sedation: respiratory and cardiovascular considerations. Anesth. Prog. 54 (2007) 59-68 quiz 69
3. Bergseth G., Lappegard K.T., Videm V., and Mollnes T.E. A novel enzyme immunoassay for plasma thrombospondin. Comparison with beta-thromboglobulin as platelet activation marker in vitro and in vivo. Thromb. Res. 99 (2000) 41-50
4. Chen D., Asahara T., Krasinski K., Witzenbichler B., Yang J., Magner M., Kearney M., Frazier W.A., Isner J.M., and Andres V. Antibody blockade of thrombospondin accelerates reendothelialization and reduces neointima formation in balloon-injured rat carotid artery. Circulation 100 (1999) 849-854
5. Hermann M., Flammer A., and Luscher T.F. Nitric oxide in hypertension. J. Clin. Hypertens. (Greenwich) 8 (2006) 17-29
6. Ignarro L.J. Nitric oxide as a unique signaling molecule in the vascular system: a historical overview. J. Physiol. Pharmacol. 53 (2002) 503-514
7. Inglessis I., Shin J.T., Lepore J.J., Palacios I.F., Zapol W.M., Bloch K.D., and Semigran M.J. Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. J. Am. Coll. Cardiol. 44 (2004) 793-798
8. Isenberg J.S., Calzada M.J., Zhou L., Guo N., Lawler J., Wang X.Q., Frazier W.A., and Roberts D.D. Endogenous thrombospondin-1 is not necessary for proliferation but is permissive for vascular smooth muscle cell responses to platelet-derived growth factor. Matrix Biol. 24 (2005) 110-123
9. Isenberg J.S., Ridnour L.A., Perruccio E.M., Espey M.G., Wink D.A., and Roberts D.D. Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 13141-13146
10. Isenberg J.S., Ridnour L.A., Dimitry J., Frazier W.A., Wink D.A., and Roberts D.D. CD47 is necessary for inhibition of nitric oxide-stimulated vascular cell responses by thrombospondin-1. J. Biol. Chem. 281 (2006) 26069-26080
11. Isenberg J.S., Wink D.A., and Roberts D.D. Thrombospondin-1 antagonizes nitric oxide-stimulated vascular smooth muscle cell responses. Cardiovasc. Res. 71 (2006) 785-793
12. Isenberg J.S., Hyodo F., Matsumoto K., Romeo M.J., Abu-Asab M., Tsokos M., Kuppusamy P., Wink D.A., Krishna M.C., and Roberts D.D. Thrombospondin-1 limits ischemic tissue survival by inhibiting nitric oxide-mediated vascular smooth muscle relaxation. Blood 109 (2007) 1945-1952
13. Isenberg J.S., Hyodo F., Pappan L.K., Abu-Asab M., Tsokos M., Krishna M.C., Frazier W.A., and Roberts D.D. Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue responses to ischemia. Arterioscler. Thromb. Vasc. Biol. 27 (2007) 2582-2588
14. Isenberg J.S., Romeo M.J., Abu-Asab M., Tsokos M., Oldenborg A., Pappan L., Wink D.A., Frazier W.A., and Roberts D.D. Increasing survival of ischemic tissue by targeting CD47. Circ. Res. 100 (2007) 712-720
15. Isenberg J.S., Romeo M.J., Yu C., Yu C.K., Nghiem K., Monsale J., Rick M.E., Wink D.A., Frazier W.A., and Roberts D.D. Thrombospondin-1 stimulates platelet aggregation by blocking the antithrombotic activity of nitric oxide/cGMP signaling. Blood 111 (2008) 613-623
16. Isenberg J.S., Annis D.S., Pendrak M.L., Ptaszynska M., Frazier W.A., Mosher D.F., and Roberts D.D. Differential interactions of thrombospondins-1, -2 and -4 with CD47 and effects on cGMP signaling and Ischemic injury responses. J Biol Chem. 284 (2009) 1116-1125
17. Kelleher C.M., McLean S.E., and Mecham R.P. Vascular extracellular matrix and aortic development. Curr. Top. Dev. Biol. 62 (2004) 153-188
18. Kojda G., and Kottenberg K. Regulation of basal myocardial function by NO. Cardiovasc. Res. 41 (1999) 514-523
19. Lamy L., Foussat A., Brown E.J., Bornstein P., Ticchioni M., and Bernard A. Interactions between CD47 and thrombospondin reduce inflammation. J. Immunol. 178 (2007) 5930-5939
20. Lee C.R., Watkins M.L., Patterson J.H., Gattis W., O'Connor C., Gheorghiade M., and Adams Jr. K.F. Vasopressin: a new target for the treatment of heart failure. Am. Heart J. 146 (2003) 9-18
21. Lee W.Y., Weber D.A., Laur O., Severson E.A., McCall I., Jen R.P., Chin A.C., Wu T., Gernert K.M., and Parkos C.A. Novel structural determinants on SIRP alpha that mediate binding to CD47. J. Immunol. 179 (2007) 7741-7750
22. Lopes N., Gregg D., Vasudevan S., Hassanain H., Goldschmidt-Clermont P., and Kovacic H. Thrombospondin 2 regulates cell proliferation induced by Rac1 redox-dependent signaling. Mol. Cell. Biol. 23 (2003) 5401-5408
23. Manna P.P., and Frazier W.A. The mechanism of CD47-dependent killing of T cells: heterotrimeric Gi-dependent inhibition of protein kinase A. J. Immunol. 170 (2003) 3544-3553
24. Medley T.L., Cole T.J., Gatzka C.D., Wang W.Y., Dart A.M., and Kingwell B.A. Fibrillin-1 genotype is associated with aortic stiffness and disease severity in patients with coronary artery disease. Circulation 105 (2002) 810-815
25. Mohan P., Brutsaert D.L., Paulus W.J., and Sys S.U. Myocardial contractile response to nitric oxide and cGMP. Circulation 93 (1996) 1223-1229
26. Mullershausen F., Friebe A., Feil R., Thompson W.J., Hofmann F., and Koesling D. Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling. J. Cell Biol. 160 (2003) 719-727
27. Ortiz P.A., and Garvin J.L. Cardiovascular and renal control in NOS-deficient mouse models. Am. J. Physiol., Regul. Integr. Comp. Physiol. 284 (2003) R628-R638
28. Prendergast B.D., Sagach V.F., and Shah A.M. Basal release of nitric oxide augments the Frank-Starling response in the isolated heart. Circulation 96 (1997) 1320-1329
29. Reich D.L., Hossain S., Krol M., Baez B., Patel P., Bernstein A., and Bodian C.A. Predictors of hypotension after induction of general anesthesia. Anesth. Analg. 101 (2005) 622-628 table of contents
30. Riessen R., Kearney M., Lawler J., and Isner J.M. Immunolocalization of thrombospondin-1 in human atherosclerotic and restenotic arteries. Am. Heart J. 135 (1998) 357-364
31. Roth J.J., Gahtan V., Brown J.L., Gerhard C., Swami V.K., Rothman V.L., Tulenko T.N., and Tuszynski G.P. Thrombospondin-1 is elevated with both intimal hyperplasia and hypercholesterolemia. J. Surg. Res. 74 (1998) 11-16
32. Rybalkin S.D., Yan C., Bornfeldt K.E., and Beavo J.A. Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ. Res. 93 (2003) 280-291
33. Scrogin K.E., Hatton D.C., Chi Y., and Luft F.C. Chronic nitric oxide inhibition with L-NAME: effects on autonomic control of the cardiovascular system. Am. J. Physiol. 274 (1998) R367-R374
34. Shah A.M., and MacCarthy P.A. Paracrine and autocrine effects of nitric oxide on myocardial function. Pharmacol. Ther. 86 (2000) 49-86
35. Shibao C., Raj S.R., Gamboa A., Diedrich A., Choi L., Black B.K., Robertson D., and Biaggioni I. Norepinephrine transporter blockade with atomoxetine induces hypertension in patients with impaired autonomic function. Hypertension 50 (2007) 47-53
36. Shifren A., Durmowicz A.G., Knutsen R.H., Faury G., and Mecham R.P. Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure. J. Appl. Physiol. 105 (2008) 1610-1619
37. Stenina O.I., Desai S.Y., Krukovets I., Kight K., Janigro D., Topol E.J., and Plow E.F. Thrombospondin-4 and its variants: expression and differential effects on endothelial cells. Circulation 108 (2003) 1514-1519
38. Stenina O.I., Krukovets I., Wang K., Zhou Z., Forudi F., Penn M.S., Topol E.J., and Plow E.F. Increased expression of thrombospondin-1 in vessel wall of diabetic Zucker rat. Circulation 107 (2003) 3209-3215
39. Thomas D.D., Miranda K.M., Espey M.G., Citrin D., Jourd'heuil D., Paolocci N., Hewett S.J., Colton C.A., Grisham M.B., Feelisch M., and Wink D.A. Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems. Methods Enzymol. 359 (2002) 84-105
40. Topol E.J., McCarthy J., Gabriel S., Moliterno D.J., Rogers W.J., Newby L.K., Freedman M., Metivier J., Cannata R., O'Donnell C.J., Kottke-Marchant K., Murugesan G., Plow E.F., Stenina O., and Daley G.Q. Single nucleotide polymorphisms in multiple novel thrombospondin genes may be associated with familial premature myocardial infarction. Circulation 104 (2001) 2641-2644
41. Torri G., Casati A., and On behalf of the Italian Research Group on sevoflurane. Cardiovascular homeostasis during inhalational general anesthesia: a clinical comparison between sevoflurane and isoflurane. J. Clin. Anesth. 12 (2000) 117-122
42. Wagenseil J.E., Nerurkar N.L., Knutsen R.H., Okamoto R.J., Li D.Y., and Mecham R.P. Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries. Am. J. Physiol., Heart Circ. Physiol. 289 (2005) H1209-H1217
43. Wagenseil J.E., Knutsen R.H., Li D.Y., and Mecham R.P. Elastin-insufficient mice show normal cardiovascular remodeling in 2K1C hypertension despite higher baseline pressure and unique cardiovascular architecture. Am. J. Physiol., Heart Circ. Physiol. 293 (2007) H574-H582
44. Wang X.Q., Lindberg F.P., and Frazier W.A. Integrin-associated protein stimulates alpha2beta1-dependent chemotaxis via Gi-mediated inhibition of adenylate cyclase and extracellular-regulated kinases. J. Cell Biol. 147 (1999) 389-400
45. Yamashita Y., Kurohiji T., Tuszynski G.P., Sakai T., and Shirakusa T. Plasma thrombospondin levels in patients with colorectal carcinoma. Cancer 82 (1998) 632-638
46. Zaccolo M., and Movsesian M.A. cAMP and cGMP signaling cross-talk: role of phosphodiesterases and implications for cardiac pathophysiology. Circ. Res. 100 (2007) 1569-1578
47. Zwicker J.I., Peyvandi F., Palla R., Lombardi R., Canciani M.T., Cairo A., Ardissino D., Bernardinelli L., Bauer K.A., Lawler J., and Mannucci P. The thrombospondin-1 N700S polymorphism is associated with early myocardial infarction without altering von Willebrand factor multimer size. Blood 108 (2006) 1280-1283