메뉴 건너뛰기




Volumn 158, Issue 6, 2017, Pages 1838-1848

Neonatal inhibition of DNA methylation alters cell phenotype in sexually dimorphic regions of the mouse brain

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN 1; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; ESTROGEN RECEPTOR ALPHA; ZEBULARINE; CYTIDINE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; PYRIMIDIN-2-ONE BETA-RIBOFURANOSIDE;

EID: 85020211756     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2017-00205     Document Type: Article
Times cited : (28)

References (51)
  • 1
    • 65549149975 scopus 로고    scopus 로고
    • The organizational hypothesis and final common pathways: Sexual differentiation of the spinal cord and peripheral nervous system
    • Forger NG. The organizational hypothesis and final common pathways: sexual differentiation of the spinal cord and peripheral nervous system. Horm Behav. 2009;55(5):605-610.
    • (2009) Horm Behav. , vol.55 , Issue.5 , pp. 605-610
    • Forger, N.G.1
  • 2
    • 33644537379 scopus 로고    scopus 로고
    • Cell death and sexual differentiation of the nervous system
    • Forger NG. Cell death and sexual differentiation of the nervous system. Neuroscience. 2006;138(3):929-938.
    • (2006) Neuroscience. , vol.138 , Issue.3 , pp. 929-938
    • Forger, N.G.1
  • 3
    • 0022397928 scopus 로고
    • Androgens prevent normally occurring cell death in a sexually dimorphic spinal nucleus
    • Nordeen EJ, Nordeen KW, Sengelaub DR, Arnold AP. Androgens prevent normally occurring cell death in a sexually dimorphic spinal nucleus. Science. 1985;229(4714):671-673.
    • (1985) Science. , vol.229 , Issue.4714 , pp. 671-673
    • Nordeen, E.J.1    Nordeen, K.W.2    Sengelaub, D.R.3    Arnold, A.P.4
  • 4
    • 0030599138 scopus 로고    scopus 로고
    • The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area
    • Davis EC, Popper P, Gorski RA. The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area. Brain Res. 1996;734(1-2):10-18.
    • (1996) Brain Res. , vol.734 , Issue.1-2 , pp. 10-18
    • Davis, E.C.1    Popper, P.2    Gorski, R.A.3
  • 6
    • 20444402211 scopus 로고    scopus 로고
    • Effects of Bax gene deletion on muscle and motoneuron degeneration in a sexually dimorphic neuromuscular system
    • Jacob DA, Bengston CL, Forger NG. Effects of Bax gene deletion on muscle and motoneuron degeneration in a sexually dimorphic neuromuscular system. J Neurosci. 2005;25(23):5638-5644.
    • (2005) J Neurosci. , vol.25 , Issue.23 , pp. 5638-5644
    • Jacob, D.A.1    Bengston, C.L.2    Forger, N.G.3
  • 8
    • 50449089708 scopus 로고    scopus 로고
    • Sexual differentiation of vasopressin innervation of the brain: Cell death versus phenotypic differentiation
    • de Vries GJ, Jardon M, Reza M, Rosen GJ, Immerman E, Forger NG. Sexual differentiation of vasopressin innervation of the brain: cell death versus phenotypic differentiation. Endocrinology. 2008; 149(9):4632-4637.
    • (2008) Endocrinology. , vol.149 , Issue.9 , pp. 4632-4637
    • De Vries, G.J.1    Jardon, M.2    Reza, M.3    Rosen, G.J.4    Immerman, E.5    Forger, N.G.6
  • 10
    • 84873841575 scopus 로고    scopus 로고
    • Effects ofblockingdevelopmental cell death on sexually dimorphic calbindin cell groups in the preoptic area and bed nucleus of the stria terminalis
    • GilmoreRF, VarnumMM,ForgerNG. Effects ofblockingdevelopmental cell death on sexually dimorphic calbindin cell groups in the preoptic area and bed nucleus of the stria terminalis. Biol Sex Differ. 2012;3:5.
    • (2012) Biol Sex Differ. , vol.3 , pp. 5
    • Gilmore, R.F.1    Varnum, M.M.2    Forger, N.G.3
  • 11
    • 34547773622 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area
    • Edelmann M, Wolfe C, Scordalakes EM, Rissman EF, Tobet S. Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area. Dev Neurobiol. 2007;67(10):1371-1381.
    • (2007) Dev Neurobiol. , vol.67 , Issue.10 , pp. 1371-1381
    • Edelmann, M.1    Wolfe, C.2    Scordalakes, E.M.3    Rissman, E.F.4    Tobet, S.5
  • 12
    • 44849087208 scopus 로고    scopus 로고
    • Sex differences in brain developing in the presence or absence of gonads
    • Büdefeld T, Grgurevic N, Tobet SA, Majdic G. Sex differences in brain developing in the presence or absence of gonads. Dev Neurobiol. 2008;68(7):981-995.
    • (2008) Dev Neurobiol. , vol.68 , Issue.7 , pp. 981-995
    • Büdefeld, T.1    Grgurevic, N.2    Tobet, S.A.3    Majdic, G.4
  • 13
    • 77954592056 scopus 로고    scopus 로고
    • Estrogen configures sexual dimorphism in the preoptic area of C57BL/6J and ddN strains of mice
    • Orikasa C, Sakuma Y. Estrogen configures sexual dimorphism in the preoptic area of C57BL/6J and ddN strains of mice. J Comp Neurol. 2010;518(17):3618-3629.
    • (2010) J Comp Neurol. , vol.518 , Issue.17 , pp. 3618-3629
    • Orikasa, C.1    Sakuma, Y.2
  • 14
    • 0028589538 scopus 로고
    • Sex differences in the development of estrogen receptors in the rat brain
    • Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ. Sex differences in the development of estrogen receptors in the rat brain. Horm Behav. 1994;28(4):483-491.
    • (1994) Horm Behav. , vol.28 , Issue.4 , pp. 483-491
    • Kühnemann, S.1    Brown, T.J.2    Hochberg, R.B.3    MacLusky, N.J.4
  • 15
    • 0030712466 scopus 로고    scopus 로고
    • Postnatal development and sex difference in neurons containing estrogen receptor-A immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat
    • Yokosuka M, Okamura H, Hayashi S. Postnatal development and sex difference in neurons containing estrogen receptor-A immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat. J Comp Neurol. 1997;389(1):81-93.
    • (1997) J Comp Neurol. , vol.389 , Issue.1 , pp. 81-93
    • Yokosuka, M.1    Okamura, H.2    Hayashi, S.3
  • 16
    • 79959563041 scopus 로고    scopus 로고
    • Sexually dimorphic expression of hypothalamic estrogen receptors a and b and Kiss1 in neonatal male and female rats
    • Cao J, Patisaul HB. Sexually dimorphic expression of hypothalamic estrogen receptors a and b and Kiss1 in neonatal male and female rats. J Comp Neurol. 2011;519(15):2954-2977.
    • (2011) J Comp Neurol. , vol.519 , Issue.15 , pp. 2954-2977
    • Cao, J.1    Patisaul, H.B.2
  • 17
    • 0029129883 scopus 로고
    • Sexual differentiation of estrogen receptor concentrations in the rat brain: Effects of neonatal testosterone exposure
    • Kühnemann S, Brown TJ, Hochberg RB, MacLusky NJ. Sexual differentiation of estrogen receptor concentrations in the rat brain: effects of neonatal testosterone exposure. BrainRes. 1995;691(1-2):229-234.
    • (1995) BrainRes. , vol.691 , Issue.1-2 , pp. 229-234
    • Kühnemann, S.1    Brown, T.J.2    Hochberg, R.B.3    MacLusky, N.J.4
  • 18
    • 0028364111 scopus 로고
    • Developmental profile of estrogen receptormRNAin the preoptic area of male and female neonatal rats
    • DonCarlos LL, Handa RJ. Developmental profile of estrogen receptormRNAin the preoptic area of male and female neonatal rats. Brain Res Dev Brain Res. 1994;79(2):283-289.
    • (1994) Brain Res Dev Brain Res. , vol.79 , Issue.2 , pp. 283-289
    • DonCarlos, L.L.1    Handa, R.J.2
  • 19
    • 0028866147 scopus 로고
    • Region-specific effects of ovarian hormones on estrogen receptor immunoreactivity
    • DonCarlos LL, Malik K, Morrell JI. Region-specific effects of ovarian hormones on estrogen receptor immunoreactivity. Neuroreport. 1995;6(15):2054-2058.
    • (1995) Neuroreport. , vol.6 , Issue.15 , pp. 2054-2058
    • DonCarlos, L.L.1    Malik, K.2    Morrell, J.I.3
  • 20
    • 0025720468 scopus 로고
    • Estrogen receptor messenger RNA expression in rat hypothalamus as a function of genetic sex and estrogen dose
    • Lauber AH, Mobbs CV, MuramatsuM, Pfaff DW. Estrogen receptor messenger RNA expression in rat hypothalamus as a function of genetic sex and estrogen dose. Endocrinology. 1991;129(6):3180-3186.
    • (1991) Endocrinology. , vol.129 , Issue.6 , pp. 3180-3186
    • Lauber, A.H.1    Mobbs, C.V.2    Muramatsu, M.3    Pfaff, D.W.4
  • 21
    • 0026683590 scopus 로고
    • Estrogen receptor messenger ribonucleic acid in female rat brain during the estrous cycle: A comparison with ovariectomized females and intact males
    • Shughrue PJ, Bushnell CD, Dorsa DM. Estrogen receptor messenger ribonucleic acid in female rat brain during the estrous cycle: A comparison with ovariectomized females and intact males. Endocrinology. 1992;131(1):381-388.
    • (1992) Endocrinology. , vol.131 , Issue.1 , pp. 381-388
    • Shughrue, P.J.1    Bushnell, C.D.2    Dorsa, D.M.3
  • 22
    • 84884692126 scopus 로고    scopus 로고
    • Differential control of sex differences in estrogen receptor a in the bed nucleus of the stria terminalis and anteroventral periventricular nucleus
    • Kelly DA, Varnum MM, Krentzel AA, Krug S, Forger NG. Differential control of sex differences in estrogen receptor a in the bed nucleus of the stria terminalis and anteroventral periventricular nucleus. Endocrinology. 2013;154(10):3836-3846.
    • (2013) Endocrinology. , vol.154 , Issue.10 , pp. 3836-3846
    • Kelly, D.A.1    Varnum, M.M.2    Krentzel, A.A.3    Krug, S.4    Forger, N.G.5
  • 23
    • 84925010738 scopus 로고    scopus 로고
    • Hypothalamic expression of oestrogen receptor a and androgen receptor is sex-, age-and regiondependent in mice
    • Brock O, De Mees C, Bakker J. Hypothalamic expression of oestrogen receptor a and androgen receptor is sex-, age-and regiondependent in mice. J Neuroendocrinol. 2015;27(4):264-276.
    • (2015) J Neuroendocrinol. , vol.27 , Issue.4 , pp. 264-276
    • Brock, O.1    De Mees, C.2    Bakker, J.3
  • 24
    • 5444244267 scopus 로고    scopus 로고
    • Epigenetic control of neural stem cell fate
    • Hsieh J, Gage FH. Epigenetic control of neural stem cell fate. Curr Opin Genet Dev. 2004;14(5):461-469.
    • (2004) Curr Opin Genet Dev. , vol.14 , Issue.5 , pp. 461-469
    • Hsieh, J.1    Gage, F.H.2
  • 25
    • 34248370597 scopus 로고    scopus 로고
    • Active tissuespecific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons
    • Zhang F, Pomerantz JH, SenG, PalermoAT,BlauHM. Active tissuespecific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. Proc Natl Acad Sci USA. 2007;104(11):4395-4400.
    • (2007) Proc Natl Acad Sci USA. , vol.104 , Issue.11 , pp. 4395-4400
    • Zhang, F.1    Pomerantz, J.H.2    Sen, G.3    Palermo, A.T.4    Blau, H.M.5
  • 27
    • 77953168537 scopus 로고    scopus 로고
    • Sex differences in epigenetic regulation of the estrogen receptor-A promoter within the developing preoptic area
    • Kurian JR, Olesen KM, Auger AP. Sex differences in epigenetic regulation of the estrogen receptor-A promoter within the developing preoptic area. Endocrinology. 2010;151(5):2297-2305.
    • (2010) Endocrinology. , vol.151 , Issue.5 , pp. 2297-2305
    • Kurian, J.R.1    Olesen, K.M.2    Auger, A.P.3
  • 28
    • 77957277418 scopus 로고    scopus 로고
    • Developmental and hormone-induced epigenetic changes to estrogen and progesterone receptor genes in brain are dynamic across the life span
    • Schwarz JM, Nugent BM, McCarthy MM. Developmental and hormone-induced epigenetic changes to estrogen and progesterone receptor genes in brain are dynamic across the life span. Endocrinology. 2010;151(10):4871-4881.
    • (2010) Endocrinology. , vol.151 , Issue.10 , pp. 4871-4881
    • Schwarz, J.M.1    Nugent, B.M.2    McCarthy, M.M.3
  • 31
    • 0034101697 scopus 로고    scopus 로고
    • Calbindin-D28k immunoreactivity is a marker for a subdivision of the sexually dimorphic nucleus of the preoptic area of the rat: Developmental profile and gonadal steroid modulation
    • Sickel MJ,McCarthy MM. Calbindin-D28k immunoreactivity is a marker for a subdivision of the sexually dimorphic nucleus of the preoptic area of the rat: developmental profile and gonadal steroid modulation. J Neuroendocrinol. 2000;12(5):397-402.
    • (2000) J Neuroendocrinol. , vol.12 , Issue.5 , pp. 397-402
    • Sickel, M.J.1    McCarthy, M.M.2
  • 33
    • 0027375278 scopus 로고
    • The 50-flanking region of the rat synapsin i gene directs neuron-specific and developmentally regulated reporter gene expression in transgenic mice
    • Hoesche C, Sauerwald A, Veh RW, Krippl B, Kilimann MW. The 50-flanking region of the rat synapsin I gene directs neuron-specific and developmentally regulated reporter gene expression in transgenic mice. J Biol Chem. 1993;268(35):26494-26502.
    • (1993) J Biol Chem. , vol.268 , Issue.35 , pp. 26494-26502
    • Hoesche, C.1    Sauerwald, A.2    Veh, R.W.3    Krippl, B.4    Kilimann, M.W.5
  • 34
    • 0035312367 scopus 로고    scopus 로고
    • Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
    • Zhu Y, Romero MI, Ghosh P, Ye Z, Charnay P, Rushing EJ, Marth JD, Parada LF. Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes Dev. 2001;15(7):859-876.
    • (2001) Genes Dev. , vol.15 , Issue.7 , pp. 859-876
    • Zhu, Y.1    Romero, M.I.2    Ghosh, P.3    Ye, Z.4    Charnay, P.5    Rushing, E.J.6    Marth, J.D.7    Parada, L.F.8
  • 35
    • 74949100523 scopus 로고    scopus 로고
    • Epigenetic regulation of estrogen receptor alpha gene expression in themouse cortex during early postnatal development
    • Westberry JM, Trout AL, Wilson ME. Epigenetic regulation of estrogen receptor alpha gene expression in themouse cortex during early postnatal development. Endocrinology. 2010;151(2):731-740.
    • (2010) Endocrinology. , vol.151 , Issue.2 , pp. 731-740
    • Westberry, J.M.1    Trout, A.L.2    Wilson, M.E.3
  • 36
    • 82055194388 scopus 로고    scopus 로고
    • Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging
    • Gore AC, Walker DM, Zama AM, Armenti AE, Uzumcu M. Early life exposure to endocrine-disrupting chemicals causes lifelong molecular reprogramming of the hypothalamus and premature reproductive aging. Mol Endocrinol. 2011;25(12):2157-2168.
    • (2011) Mol Endocrinol. , vol.25 , Issue.12 , pp. 2157-2168
    • Gore, A.C.1    Walker, D.M.2    Zama, A.M.3    Armenti, A.E.4    Uzumcu, M.5
  • 37
    • 0042905956 scopus 로고    scopus 로고
    • Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: Defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines
    • Glaser KB, Staver MJ, Waring JF, Stender J, Ulrich RG, Davidsen SK. Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. Mol Cancer Ther. 2003;2(2):151-163.
    • (2003) Mol Cancer Ther. , vol.2 , Issue.2 , pp. 151-163
    • Glaser, K.B.1    Staver, M.J.2    Waring, J.F.3    Stender, J.4    Ulrich, R.G.5    Davidsen, S.K.6
  • 39
    • 84858242057 scopus 로고    scopus 로고
    • Neonatal MeCP2 is important for the organization of sex differences in vasopressin expression
    • Forbes-Lorman RM, Rautio JJ, Kurian JR, Auger AP, Auger CJ. Neonatal MeCP2 is important for the organization of sex differences in vasopressin expression. Epigenetics. 2012;7(3):230-238.
    • (2012) Epigenetics. , vol.7 , Issue.3 , pp. 230-238
    • Forbes-Lorman, R.M.1    Rautio, J.J.2    Kurian, J.R.3    Auger, A.P.4    Auger, C.J.5
  • 41
    • 84956687644 scopus 로고    scopus 로고
    • Multifaceted origins of sex differences in the brain
    • McCarthyMM.Multifaceted origins of sex differences in the brain. Philos Trans R Soc Lond B Biol Sci. 2016;371(1688):20150106.
    • (2016) Philos Trans R Soc Lond B Biol Sci. , vol.371 , Issue.1688 , pp. 20150106
    • McCarthy, M.M.1
  • 42
    • 84956677652 scopus 로고    scopus 로고
    • Epigenetic mechanisms in sexual differentiation of the brain and behaviour
    • Forger NG. Epigenetic mechanisms in sexual differentiation of the brain and behaviour. Philos Trans R Soc Lond B Biol Sci. 2016; 371(1688):20150114.
    • (2016) Philos Trans R Soc Lond B Biol Sci. , vol.371 , Issue.1688 , pp. 20150114
    • Forger, N.G.1
  • 43
    • 77950187447 scopus 로고    scopus 로고
    • Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
    • Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G. Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. NatNeurosci. 2010;13(4):423-430.
    • (2010) NatNeurosci. , vol.13 , Issue.4 , pp. 423-430
    • Feng, J.1    Zhou, Y.2    Campbell, S.L.3    Le, T.4    Li, E.5    Sweatt, J.D.6    Silva, A.J.7    Fan, G.8
  • 44
    • 84961262437 scopus 로고    scopus 로고
    • The "de novo" DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium
    • Elliott EN, Sheaffer KL, Kaestner KH. The "de novo" DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium. eLife. 2016;5:5.
    • (2016) ELife. , vol.5 , pp. 5
    • Elliott, E.N.1    Sheaffer, K.L.2    Kaestner, K.H.3
  • 46
    • 0023801293 scopus 로고
    • Regional sex differences in cell nuclear estrogen-binding capacity in the rat hypothalamus and preoptic area
    • Brown TJ, Hochberg RB, Zielinski JE, MacLusky NJ. Regional sex differences in cell nuclear estrogen-binding capacity in the rat hypothalamus and preoptic area. Endocrinology. 1988;123(4):1761-1770.
    • (1988) Endocrinology. , vol.123 , Issue.4 , pp. 1761-1770
    • Brown, T.J.1    Hochberg, R.B.2    Zielinski, J.E.3    MacLusky, N.J.4
  • 47
    • 0032497623 scopus 로고    scopus 로고
    • Neuronal diversity: Too many cell types for comfort?
    • Stevens CF. Neuronal diversity: too many cell types for comfort? Curr Biol. 1998;8(20):R708-R710.
    • (1998) Curr Biol. , vol.8 , Issue.20 , pp. R708-R710
    • Stevens, C.F.1
  • 48
    • 33749063646 scopus 로고    scopus 로고
    • Probing the transcriptome of neuronal cell types
    • Nelson SB, Hempel C, Sugino K. Probing the transcriptome of neuronal cell types. Curr Opin Neurobiol. 2006;16(5):571-576.
    • (2006) Curr Opin Neurobiol. , vol.16 , Issue.5 , pp. 571-576
    • Nelson, S.B.1    Hempel, C.2    Sugino, K.3
  • 49
    • 0033593304 scopus 로고    scopus 로고
    • Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system
    • Edlund T, Jessell TM. Progression from extrinsic to intrinsic signaling in cell fate specification: A view from the nervous system. Cell. 1999;96(2):211-224.
    • (1999) Cell. , vol.96 , Issue.2 , pp. 211-224
    • Edlund, T.1    Jessell, T.M.2
  • 50
    • 84862070237 scopus 로고    scopus 로고
    • Maintaining differentiated cellular identity
    • Holmberg J, Perlmann T. Maintaining differentiated cellular identity. Nat Rev Genet. 2012;13(6):429-439.
    • (2012) Nat Rev Genet. , vol.13 , Issue.6 , pp. 429-439
    • Holmberg, J.1    Perlmann, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.