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Volumn 27, Issue 4, 2015, Pages 264-276

Hypothalamic expression of oestrogen receptor α and androgen receptor is sex-, age- and region-dependent in mice

Author keywords

Aromatase knockout mice; Dihydrotestosterone; Oestradiol; Perinatal period; Sex differences

Indexed keywords

ANDROGEN RECEPTOR; ANDROSTANOLONE; AROMATASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; TESTOSTERONE;

EID: 84925010738     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12258     Document Type: Article
Times cited : (69)

References (67)
  • 1
    • 79955785219 scopus 로고    scopus 로고
    • The development of female sexual behavior requires prepubertal estradiol
    • Brock O, Baum MJ, Bakker J. The development of female sexual behavior requires prepubertal estradiol. J Neurosci 2011; 31: 5574-5578.
    • (2011) J Neurosci , vol.31 , pp. 5574-5578
    • Brock, O.1    Baum, M.J.2    Bakker, J.3
  • 2
    • 0033304886 scopus 로고    scopus 로고
    • Clinical review 108: the molecular and neuroanatomical basis for estrogen effects in the central nervous system
    • McEwen BS. Clinical review 108: the molecular and neuroanatomical basis for estrogen effects in the central nervous system. J Clin Endocrinol Metab 1999; 84: 1790-1797.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1790-1797
    • McEwen, B.S.1
  • 3
    • 0033304765 scopus 로고    scopus 로고
    • Estrogen actions in the central nervous system
    • McEwen BS, Alves SE. Estrogen actions in the central nervous system. Endocr Rev 1999; 20: 279-307.
    • (1999) Endocr Rev , vol.20 , pp. 279-307
    • McEwen, B.S.1    Alves, S.E.2
  • 5
    • 0032079533 scopus 로고    scopus 로고
    • Organization and regulation of sexually dimorphic neuroendocrine pathways
    • Simerly RB. Organization and regulation of sexually dimorphic neuroendocrine pathways. Behav Brain Res 1998; 92: 195-203.
    • (1998) Behav Brain Res , vol.92 , pp. 195-203
    • Simerly, R.B.1
  • 6
    • 9644265650 scopus 로고    scopus 로고
    • Estrogen and the brain: beyond ER-alpha and ER-beta
    • Toran-Allerand CD. Estrogen and the brain: beyond ER-alpha and ER-beta. Exp Gerontol 2004; 39: 1579-1586.
    • (2004) Exp Gerontol , vol.39 , pp. 1579-1586
    • Toran-Allerand, C.D.1
  • 10
    • 0023628759 scopus 로고
    • Structural organization and expression of the mouse estrogen receptor
    • White R, Lees JA, Needham M, Ham J, Parker M. Structural organization and expression of the mouse estrogen receptor. Mol Endocrinol 1987; 1: 735-744.
    • (1987) Mol Endocrinol , vol.1 , pp. 735-744
    • White, R.1    Lees, J.A.2    Needham, M.3    Ham, J.4    Parker, M.5
  • 12
    • 65549120393 scopus 로고    scopus 로고
    • Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses
    • Raskin K, de Gendt K, Duittoz A, Liere P, Verhoeven G, Tronche F, Mhaouty-Kodja S. Conditional inactivation of androgen receptor gene in the nervous system: effects on male behavioral and neuroendocrine responses. J Neurosci 2009; 29: 4461-4470.
    • (2009) J Neurosci , vol.29 , pp. 4461-4470
    • Raskin, K.1    de Gendt, K.2    Duittoz, A.3    Liere, P.4    Verhoeven, G.5    Tronche, F.6    Mhaouty-Kodja, S.7
  • 13
    • 21644486465 scopus 로고    scopus 로고
    • Estrogen receptor knockout mice as a model for endocrine research
    • Walker VR, Korach KS. Estrogen receptor knockout mice as a model for endocrine research. ILAR 2004; 45: 455-461.
    • (2004) ILAR , vol.45 , pp. 455-461
    • Walker, V.R.1    Korach, K.S.2
  • 15
    • 0033616449 scopus 로고    scopus 로고
    • Androgen receptor immunoreactivity in specific neural regions in normal and hypogonadal male mice: effect of androgens
    • Apostolinas S, Rajendren G, Dobrjansky A, Gibson MJ. Androgen receptor immunoreactivity in specific neural regions in normal and hypogonadal male mice: effect of androgens. Brain Res 1999; 817: 19-24.
    • (1999) Brain Res , vol.817 , pp. 19-24
    • Apostolinas, S.1    Rajendren, G.2    Dobrjansky, A.3    Gibson, M.J.4
  • 16
    • 0031550620 scopus 로고    scopus 로고
    • Quantitative estimation of estrogen and androgen receptor-immunoreactive cells in the forebrain of neonatally estrogen-deprived male rats
    • Bakker J, Pool CW, Sonnemans M, van Leeuwen FW, Slob AK. Quantitative estimation of estrogen and androgen receptor-immunoreactive cells in the forebrain of neonatally estrogen-deprived male rats. Neuroscience 1997; 77: 911-919.
    • (1997) Neuroscience , vol.77 , pp. 911-919
    • Bakker, J.1    Pool, C.W.2    Sonnemans, M.3    van Leeuwen, F.W.4    Slob, A.K.5
  • 17
    • 0142126332 scopus 로고    scopus 로고
    • Stereologic analysis of estrogen receptor alpha (ER alpha) expression in rat hypothalamus and its regulation by aging and estrogen
    • Chakraborty TR, Hof PR, Ng L, Gore AC. Stereologic analysis of estrogen receptor alpha (ER alpha) expression in rat hypothalamus and its regulation by aging and estrogen. J Comp Neurol 2003; 466: 409-421.
    • (2003) J Comp Neurol , vol.466 , pp. 409-421
    • Chakraborty, T.R.1    Hof, P.R.2    Ng, L.3    Gore, A.C.4
  • 18
    • 2342584831 scopus 로고    scopus 로고
    • Distribution of estrogen receptor alpha and beta in the mouse central nervous system: in vivo autoradiographic and immunocytochemical analyses
    • Merchenthaler I, Lane MV, Numan S, Dellovade TL. Distribution of estrogen receptor alpha and beta in the mouse central nervous system: in vivo autoradiographic and immunocytochemical analyses. J Comp Neurol 2004; 473: 270-291.
    • (2004) J Comp Neurol , vol.473 , pp. 270-291
    • Merchenthaler, I.1    Lane, M.V.2    Numan, S.3    Dellovade, T.L.4
  • 20
    • 84884692126 scopus 로고    scopus 로고
    • Differential control of sex differences in estrogen receptor α in the bed nucleus of the stria terminalis and anteroventral periventricular nucleus
    • Kelly DA, Varnum MM, Krentzel AA, Krug S, Forger NG. Differential control of sex differences in estrogen receptor α in the bed nucleus of the stria terminalis and anteroventral periventricular nucleus. Endocrinology 2013; 154: 3836-3846.
    • (2013) Endocrinology , vol.154 , pp. 3836-3846
    • Kelly, D.A.1    Varnum, M.M.2    Krentzel, A.A.3    Krug, S.4    Forger, N.G.5
  • 21
    • 0031765501 scopus 로고    scopus 로고
    • Androgen receptor in mouse brain: sex differences and similarities in autoregulation
    • Lu SF, McKenna SE, Cologer-Clifford A, Nau EA, Simon NG. Androgen receptor in mouse brain: sex differences and similarities in autoregulation. Endocrinology 1998; 139: 1594-1601.
    • (1998) Endocrinology , vol.139 , pp. 1594-1601
    • Lu, S.F.1    McKenna, S.E.2    Cologer-Clifford, A.3    Nau, E.A.4    Simon, N.G.5
  • 22
    • 0033516257 scopus 로고    scopus 로고
    • The preoptic area/anterior hypothalamus of different strains of mice: sex differences and development
    • Brown AE, Mani S, Tobet SA. The preoptic area/anterior hypothalamus of different strains of mice: sex differences and development. Brain Res Dev Brain Res 1999; 115: 171-182.
    • (1999) Brain Res Dev Brain Res , vol.115 , pp. 171-182
    • Brown, A.E.1    Mani, S.2    Tobet, S.A.3
  • 23
    • 0030712466 scopus 로고    scopus 로고
    • Postnatal development and sex difference in neurons containing estrogen receptor-alpha immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat
    • Yokosuka M, Okamura H, Hayashi S. Postnatal development and sex difference in neurons containing estrogen receptor-alpha immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat. J Comp Neurol 1997; 389: 81-93.
    • (1997) J Comp Neurol , vol.389 , pp. 81-93
    • Yokosuka, M.1    Okamura, H.2    Hayashi, S.3
  • 24
    • 0028286323 scopus 로고
    • Estrogen receptor immunoreactivity in specific brain areas of the prairie vole (Microtus ochrogaster) is altered by sexual receptivity and genetic sex
    • Hnatczuk OC, Lisciotto CA, DonCarlos LL, Carter CS, Morrell JI. Estrogen receptor immunoreactivity in specific brain areas of the prairie vole (Microtus ochrogaster) is altered by sexual receptivity and genetic sex. J Neuroendocrinol 1994; 6: 89-100.
    • (1994) J Neuroendocrinol , vol.6 , pp. 89-100
    • Hnatczuk, O.C.1    Lisciotto, C.A.2    DonCarlos, L.L.3    Carter, C.S.4    Morrell, J.I.5
  • 25
    • 0028604596 scopus 로고
    • Induction of substance P-immunoreactivity by estrogen in neurons containing estrogen receptors in the anterovental periventricular nucleus of female but not male rats
    • Okamura H, Yokosuka M, Hayashi S. Induction of substance P-immunoreactivity by estrogen in neurons containing estrogen receptors in the anterovental periventricular nucleus of female but not male rats. J Neuroendocrinol 1994; 6: 609-615.
    • (1994) J Neuroendocrinol , vol.6 , pp. 609-615
    • Okamura, H.1    Yokosuka, M.2    Hayashi, S.3
  • 26
    • 33645840142 scopus 로고    scopus 로고
    • Comparative analysis of immunoreactive cells for androgen receptors and oestrogen receptor alpha in copulating and non-copulating male rats
    • Portillo W, Diaz NF, Cabrera EA, Fernandez-Guasti A, Paredes RG. Comparative analysis of immunoreactive cells for androgen receptors and oestrogen receptor alpha in copulating and non-copulating male rats. J Neuroendocrinol 2006; 18: 168-176.
    • (2006) J Neuroendocrinol , vol.18 , pp. 168-176
    • Portillo, W.1    Diaz, N.F.2    Cabrera, E.A.3    Fernandez-Guasti, A.4    Paredes, R.G.5
  • 27
    • 79959563041 scopus 로고    scopus 로고
    • Sexually dimorphic expression of hypothalamic estrogen receptors alpha and beta and Kiss1 in neonatal male and female rats
    • Cao J, Patisaul HB. Sexually dimorphic expression of hypothalamic estrogen receptors alpha and beta and Kiss1 in neonatal male and female rats. J Comp Neurol 2011; 519: 2954-2977.
    • (2011) J Comp Neurol , vol.519 , pp. 2954-2977
    • Cao, J.1    Patisaul, H.B.2
  • 28
    • 1642374926 scopus 로고    scopus 로고
    • Distribution of estrogen receptor alpha and beta immunoreactive profiles in the postnatal rat brain
    • Perez SE, Chen EY, Mufson EJ. Distribution of estrogen receptor alpha and beta immunoreactive profiles in the postnatal rat brain. Brain Res Dev Brain Res 2003; 145: 117-139.
    • (2003) Brain Res Dev Brain Res , vol.145 , pp. 117-139
    • Perez, S.E.1    Chen, E.Y.2    Mufson, E.J.3
  • 29
    • 0036308456 scopus 로고    scopus 로고
    • Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain
    • Simerly RB. Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 2002; 25: 507-536.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 507-536
    • Simerly, R.B.1
  • 30
    • 34548574848 scopus 로고    scopus 로고
    • Effects of organisational oestradiol on adult immunoreactive oestrogen receptors (alpha and beta) in the male mouse brain
    • Kudwa AE, Harada N, Honda SI, Rissman EF. Effects of organisational oestradiol on adult immunoreactive oestrogen receptors (alpha and beta) in the male mouse brain. J Neuroendocrinol 2007; 19: 767-772.
    • (2007) J Neuroendocrinol , vol.19 , pp. 767-772
    • Kudwa, A.E.1    Harada, N.2    Honda, S.I.3    Rissman, E.F.4
  • 31
    • 2942594757 scopus 로고    scopus 로고
    • Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice
    • Bakker J, Honda S, Harada N, Balthazart J. Restoration of male sexual behavior by adult exogenous estrogens in male aromatase knockout mice. Horm Behav 2004; 46: 1-10.
    • (2004) Horm Behav , vol.46 , pp. 1-10
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 32
    • 45749105175 scopus 로고    scopus 로고
    • Roles of oestrogen receptors alpha and beta in behavioural neuroendocrinology: beyond Yin/Yang
    • Rissman EF. Roles of oestrogen receptors alpha and beta in behavioural neuroendocrinology: beyond Yin/Yang. J Neuroendocrinol 2008; 20: 873-879.
    • (2008) J Neuroendocrinol , vol.20 , pp. 873-879
    • Rissman, E.F.1
  • 33
    • 0032545031 scopus 로고    scopus 로고
    • Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene
    • Honda S, Harada N, Ito S, Takagi Y, Maeda S. Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. Biochem Biophys Res Commun 1998; 252: 445-449.
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 445-449
    • Honda, S.1    Harada, N.2    Ito, S.3    Takagi, Y.4    Maeda, S.5
  • 34
    • 0037109763 scopus 로고    scopus 로고
    • The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood
    • Bakker J, Honda S, Harada N, Balthazart J. The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood. J Neurosci 2002; 22: 9104-9112.
    • (2002) J Neurosci , vol.22 , pp. 9104-9112
    • Bakker, J.1    Honda, S.2    Harada, N.3    Balthazart, J.4
  • 35
    • 0028876068 scopus 로고
    • Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice
    • Singh J, O'Neill C, Handelsman DJ. Induction of spermatogenesis by androgens in gonadotropin-deficient (hpg) mice. Endocrinology 1995; 136: 5311-5321.
    • (1995) Endocrinology , vol.136 , pp. 5311-5321
    • Singh, J.1    O'Neill, C.2    Handelsman, D.J.3
  • 36
    • 0035206886 scopus 로고    scopus 로고
    • Coexpression of ER beta with ER alpha and progestin receptor proteins in the female rat forebrain: effects of estradiol treatment
    • Greco B, Allegretto EA, Tetel MJ, Blaustein JD. Coexpression of ER beta with ER alpha and progestin receptor proteins in the female rat forebrain: effects of estradiol treatment. Endocrinology 2001; 142: 5172-5181.
    • (2001) Endocrinology , vol.142 , pp. 5172-5181
    • Greco, B.1    Allegretto, E.A.2    Tetel, M.J.3    Blaustein, J.D.4
  • 37
    • 0037871604 scopus 로고    scopus 로고
    • Response of ERalpha-IR and ERbeta-IR cells in the forebrain of female rats to mating stimuli
    • Greco B, Blasberg ME, Kosinski EC, Blaustein JD. Response of ERalpha-IR and ERbeta-IR cells in the forebrain of female rats to mating stimuli. Horm Behav 2003; 43: 444-453.
    • (2003) Horm Behav , vol.43 , pp. 444-453
    • Greco, B.1    Blasberg, M.E.2    Kosinski, E.C.3    Blaustein, J.D.4
  • 38
    • 65249190781 scopus 로고    scopus 로고
    • Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that ecompasses most stages of folliculogenesis
    • Lenie S, Smitz J. Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that ecompasses most stages of folliculogenesis. Biol Reprod 2009; 80: 685-695.
    • (2009) Biol Reprod , vol.80 , pp. 685-695
    • Lenie, S.1    Smitz, J.2
  • 39
    • 77955401721 scopus 로고    scopus 로고
    • Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling
    • D'Antonio JM, Vander Griend DJ, Antony L, Ndikuyeze G, Dalrymple SL, Koochekpour S, Isaacs JT. Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling. PLoS ONE 2010; 5: e11475.
    • (2010) PLoS ONE , vol.5 , pp. e11475
    • D'Antonio, J.M.1    Vander, G.D.2    Antony, L.3    Ndikuyeze, G.4    Dalrymple, S.L.5    Koochekpour, S.6    Isaacs, J.T.7
  • 40
    • 0030199895 scopus 로고    scopus 로고
    • Exogenous estrogen acts differently on production of estrogen receptor in the preoptic area and the mediobasal hypothalamic nuclei in the newborn rat
    • Orikasa C, Mizuno K, Sakuma Y, Hayashi S. Exogenous estrogen acts differently on production of estrogen receptor in the preoptic area and the mediobasal hypothalamic nuclei in the newborn rat. Neurosci Res 1996; 25: 247-254.
    • (1996) Neurosci Res , vol.25 , pp. 247-254
    • Orikasa, C.1    Mizuno, K.2    Sakuma, Y.3    Hayashi, S.4
  • 41
    • 0027240584 scopus 로고
    • Identification of an isoform of the estrogen receptor messenger RNA lacking exon four and present in the brain
    • Skipper JK, Young LJ, Bergeron JM, Tetzlaff MT, Osborn CT, Crews D. Identification of an isoform of the estrogen receptor messenger RNA lacking exon four and present in the brain. Proc Natl Acad Sci USA 1993; 90: 7172-7175.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7172-7175
    • Skipper, J.K.1    Young, L.J.2    Bergeron, J.M.3    Tetzlaff, M.T.4    Osborn, C.T.5    Crews, D.6
  • 42
    • 0025826394 scopus 로고
    • Steroidogenesis during postnatal development in the mouse ovary
    • Mannan MA, O'Shaughnessy PJ. Steroidogenesis during postnatal development in the mouse ovary. J Endocrinol 1991; 130: 101-106.
    • (1991) J Endocrinol , vol.130 , pp. 101-106
    • Mannan, M.A.1    O'Shaughnessy, P.J.2
  • 43
    • 33644525281 scopus 로고    scopus 로고
    • Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through an antiestrogenic action
    • De Mees C, Laes JF, Bakker J, Smitz J, Hennuy B, Van Vooren P, Gabant P, Szpirer J, Szpirer C. Alpha-fetoprotein controls female fertility and prenatal development of the gonadotropin-releasing hormone pathway through an antiestrogenic action. Mol Cell Biol 2006; 26: 2012-2018.
    • (2006) Mol Cell Biol , vol.26 , pp. 2012-2018
    • De Mees, C.1    Laes, J.F.2    Bakker, J.3    Smitz, J.4    Hennuy, B.5    Van Vooren, P.6    Gabant, P.7    Szpirer, J.8    Szpirer, C.9
  • 44
    • 0016718925 scopus 로고
    • Role of fetoneonatal estrogen binding proteins in the associations of estrogen with neonatal brain cell nuclear receptors
    • McEwen BS, Plapinger L, Chaptal C, Gerlach J, Wallach G. Role of fetoneonatal estrogen binding proteins in the associations of estrogen with neonatal brain cell nuclear receptors. Brain Res 1975; 96: 400-406.
    • (1975) Brain Res , vol.96 , pp. 400-406
    • McEwen, B.S.1    Plapinger, L.2    Chaptal, C.3    Gerlach, J.4    Wallach, G.5
  • 45
    • 2442499103 scopus 로고    scopus 로고
    • Brain estradiol content in newborn rats: sex differences, regional heterogeneity, and possible de novo synthesis by the female telencephalon
    • Amateau SK, Alt JJ, Stamps CL, McCarthy MM. Brain estradiol content in newborn rats: sex differences, regional heterogeneity, and possible de novo synthesis by the female telencephalon. Endocrinology 2004; 145: 2906-2917.
    • (2004) Endocrinology , vol.145 , pp. 2906-2917
    • Amateau, S.K.1    Alt, J.J.2    Stamps, C.L.3    McCarthy, M.M.4
  • 46
    • 0030848135 scopus 로고    scopus 로고
    • Transient sex differences of aromatase (CYP19) mRNA expression in the developing rat brain
    • Lauber ME, Sarasin A, Lichtensteiger W. Transient sex differences of aromatase (CYP19) mRNA expression in the developing rat brain. Neuroendocrinology 1997; 66: 173-180.
    • (1997) Neuroendocrinology , vol.66 , pp. 173-180
    • Lauber, M.E.1    Sarasin, A.2    Lichtensteiger, W.3
  • 48
    • 0031686279 scopus 로고    scopus 로고
    • Developmental sex differences in estrogen receptor-beta mRNA expression in the mouse hypothalamus/preoptic region
    • Karolczak M, Beyer C. Developmental sex differences in estrogen receptor-beta mRNA expression in the mouse hypothalamus/preoptic region. Neuroendocrinology 1998; 68: 229-234.
    • (1998) Neuroendocrinology , vol.68 , pp. 229-234
    • Karolczak, M.1    Beyer, C.2
  • 49
    • 33644552762 scopus 로고    scopus 로고
    • Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior
    • Kudwa AE, Michopoulos V, Gatewood JD, Rissman EF. Roles of estrogen receptors alpha and beta in differentiation of mouse sexual behavior. Neuroscience 2006; 138: 921-928.
    • (2006) Neuroscience , vol.138 , pp. 921-928
    • Kudwa, A.E.1    Michopoulos, V.2    Gatewood, J.D.3    Rissman, E.F.4
  • 50
    • 0038434285 scopus 로고    scopus 로고
    • Anatomy, development, and function of sexually dimorphic neural circuits in the mammalian brain
    • Pfaff DWAA, Etgen AM, Fahrbach SE, Rubin RT, eds. San Diego, CA: Academic Press.
    • De VD, Simerly C. Anatomy, development, and function of sexually dimorphic neural circuits in the mammalian brain. In: Pfaff DWAA, Etgen AM, Fahrbach SE, Rubin RT, eds. Hormones, Brain and Behavior. San Diego, CA: Academic Press; 2002: 137-191.
    • (2002) Hormones, Brain and Behavior , pp. 137-191
    • De, V.D.1    Simerly, C.2
  • 51
    • 0023814895 scopus 로고
    • Axon-sparing lesions of the preoptic region and substantia innominata disrupt maternal behavior in rats
    • Numan M, Corodimas KP, Numan MJ, Factor EM, Piers WD. Axon-sparing lesions of the preoptic region and substantia innominata disrupt maternal behavior in rats. Behav Neurosci 1988; 102: 381-396.
    • (1988) Behav Neurosci , vol.102 , pp. 381-396
    • Numan, M.1    Corodimas, K.P.2    Numan, M.J.3    Factor, E.M.4    Piers, W.D.5
  • 52
    • 0141887138 scopus 로고    scopus 로고
    • Medial preoptic area/anterior hypothalamus and sexual motivation
    • Paredes RG. Medial preoptic area/anterior hypothalamus and sexual motivation. Scand J Psychol 2003; 44: 203-212.
    • (2003) Scand J Psychol , vol.44 , pp. 203-212
    • Paredes, R.G.1
  • 53
    • 0016804566 scopus 로고
    • Changes with age in levels of serum gonadotropins, prolactin and gonadal steroids in prepubertal male and female rats
    • Dohler KD, Wuttke W. Changes with age in levels of serum gonadotropins, prolactin and gonadal steroids in prepubertal male and female rats. Endocrinology 1975; 97: 898-907.
    • (1975) Endocrinology , vol.97 , pp. 898-907
    • Dohler, K.D.1    Wuttke, W.2
  • 54
    • 78650824047 scopus 로고    scopus 로고
    • Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discrete regions of male and female rat brain
    • Konkle AT, McCarthy MM. Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discrete regions of male and female rat brain. Endocrinology 2011; 152: 223-235.
    • (2011) Endocrinology , vol.152 , pp. 223-235
    • Konkle, A.T.1    McCarthy, M.M.2
  • 55
    • 0022376599 scopus 로고
    • Estrogen formation in the developing rat brain: sex differences in aromatase activity during early post-natal life
    • MacLusky NJ, Philip A, Hurlburt C, Naftolin F. Estrogen formation in the developing rat brain: sex differences in aromatase activity during early post-natal life. Psychoneuroendocrinology 1985; 10: 355-361.
    • (1985) Psychoneuroendocrinology , vol.10 , pp. 355-361
    • MacLusky, N.J.1    Philip, A.2    Hurlburt, C.3    Naftolin, F.4
  • 56
    • 0027269413 scopus 로고
    • Aromatase activity in the rat brain: hormonal regulation and sex differences
    • Roselli CE, Resko JA. Aromatase activity in the rat brain: hormonal regulation and sex differences. J Steroid Biochem Mol Biol 1993; 44: 499-508.
    • (1993) J Steroid Biochem Mol Biol , vol.44 , pp. 499-508
    • Roselli, C.E.1    Resko, J.A.2
  • 57
    • 0025794333 scopus 로고
    • Regulation of estrogen receptor messenger ribonucleic acid in rat hypothalamus by sex steroid hormones
    • Simerly RB, Young BJ. Regulation of estrogen receptor messenger ribonucleic acid in rat hypothalamus by sex steroid hormones. Mol Endocrinol 1991; 5: 424-432.
    • (1991) Mol Endocrinol , vol.5 , pp. 424-432
    • Simerly, R.B.1    Young, B.J.2
  • 58
    • 0025909693 scopus 로고
    • The effect of estrogen on the estrogen receptor-immunoreactive cells in the rat medial preoptic nucleus
    • Yuri K, Kawata M. The effect of estrogen on the estrogen receptor-immunoreactive cells in the rat medial preoptic nucleus. Brain Res 1991; 548: 50-54.
    • (1991) Brain Res , vol.548 , pp. 50-54
    • Yuri, K.1    Kawata, M.2
  • 59
    • 84889663948 scopus 로고    scopus 로고
    • Estrogen receptor beta expression in the mouse forebrain: age and sex differences
    • Zuloaga DG, Zuloaga KL, Hinds LR, Carbone DL, Handa RJ. Estrogen receptor beta expression in the mouse forebrain: age and sex differences. J Comp Neurol 2014; 522: 358-371.
    • (2014) J Comp Neurol , vol.522 , pp. 358-371
    • Zuloaga, D.G.1    Zuloaga, K.L.2    Hinds, L.R.3    Carbone, D.L.4    Handa, R.J.5
  • 60
    • 15444381068 scopus 로고    scopus 로고
    • A previously uncharacterized role for estrogen receptor beta: defeminization of male brain and behavior
    • Kudwa AE, Bodo C, Gustafsson JA, Rissman EF. A previously uncharacterized role for estrogen receptor beta: defeminization of male brain and behavior. Proc Natl Acad Sci USA 2005; 102: 4608-4612.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4608-4612
    • Kudwa, A.E.1    Bodo, C.2    Gustafsson, J.A.3    Rissman, E.F.4
  • 61
    • 53949099155 scopus 로고    scopus 로고
    • Oestrogen receptor α and β immunoreactive cells in the suprachiasmatic nucleus of mice: distribution, sex differences and regulation by gonadal hormones
    • Vida B, Hrabovszky E, Kalamatianos T, Coen CW, Liposits Z, Kallo I. Oestrogen receptor α and β immunoreactive cells in the suprachiasmatic nucleus of mice: distribution, sex differences and regulation by gonadal hormones. J Neuroendocrinol 2008; 20: 1270-1277.
    • (2008) J Neuroendocrinol , vol.20 , pp. 1270-1277
    • Vida, B.1    Hrabovszky, E.2    Kalamatianos, T.3    Coen, C.W.4    Liposits, Z.5    Kallo, I.6
  • 62
    • 0019797807 scopus 로고
    • Sexual differentiation of the central nervous system
    • MacLusky NJ, Naftolin F. Sexual differentiation of the central nervous system. Science 1981; 211: 1294-1302.
    • (1981) Science , vol.211 , pp. 1294-1302
    • MacLusky, N.J.1    Naftolin, F.2
  • 63
    • 0017611195 scopus 로고
    • Aromatization: important for sexual differentiation of the neonatal rat brain
    • McEwen BS, Lieberburg I, Chaptal C, Krey LC. Aromatization: important for sexual differentiation of the neonatal rat brain. Horm Behav 1977; 9: 249-263.
    • (1977) Horm Behav , vol.9 , pp. 249-263
    • McEwen, B.S.1    Lieberburg, I.2    Chaptal, C.3    Krey, L.C.4
  • 64
    • 0031753941 scopus 로고    scopus 로고
    • Ontogeny and autoregulation of androgen receptor mRNA expression in the nervous system
    • Young WJ, Chang C. Ontogeny and autoregulation of androgen receptor mRNA expression in the nervous system. Endocrine 1998; 9: 79-88.
    • (1998) Endocrine , vol.9 , pp. 79-88
    • Young, W.J.1    Chang, C.2
  • 65
    • 77957124567 scopus 로고    scopus 로고
    • The role of the medial preoptic area in appetitive and consummatory reproductive behaviors depends on sexual experience and odor volatility in male Syrian hamsters
    • Been LE, Petrulis A. The role of the medial preoptic area in appetitive and consummatory reproductive behaviors depends on sexual experience and odor volatility in male Syrian hamsters. Neuroscience 2010; 170: 1120-1132.
    • (2010) Neuroscience , vol.170 , pp. 1120-1132
    • Been, L.E.1    Petrulis, A.2
  • 66
    • 34248573679 scopus 로고    scopus 로고
    • Effects of castration and hormone replacement on male sexual behavior and pattern of expression in the brain of sex-steroid receptors in BALB/c AnN mice
    • Arteaga-Silva M, Rodriguez-Dorantes M, Baig S, Morales-Monto J. Effects of castration and hormone replacement on male sexual behavior and pattern of expression in the brain of sex-steroid receptors in BALB/c AnN mice. Comp Biochem Physiol A Mol Integr Physiol 2007; 147: 607-615.
    • (2007) Comp Biochem Physiol A Mol Integr Physiol , vol.147 , pp. 607-615
    • Arteaga-Silva, M.1    Rodriguez-Dorantes, M.2    Baig, S.3    Morales-Monto, J.4
  • 67
    • 84881321903 scopus 로고    scopus 로고
    • Visualising androgen receptor activity in male and female mice
    • Dart DA, Waxman J, Aboagye EO, Bevan CL. Visualising androgen receptor activity in male and female mice. PLoS ONE 2013; 8: e71694.
    • (2013) PLoS ONE , vol.8 , pp. e71694
    • Dart, D.A.1    Waxman, J.2    Aboagye, E.O.3    Bevan, C.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.