Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiological stress

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 312, Issue 6, 2017, Pages G559-G571

  Karl, J Philip ^a   Margolis, Lee M ^a   Madslien, Elisabeth H ^b   Murphy, Nancy E ^a   Castellani, John W ^a   Gundersen, Yngvar ^b   Hoke, Allison V ^c,d   Levangie, Michael W ^c,d   Kumar, Raina ^e   Chakraborty, Nabarun ^c,d   Gautam, Aarti ^c   Hammamieh, Rasha ^c   Martini, Svein ^b   Montain, Scott J ^a   Pasiakos, Stefan M ^a  

^a U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

^b NORWEGIAN DEFENCE RESEARCH ESTABLISHMENT FFI   (Norway)

^c U S ARMY   (United States)

^d Geneva Foundation   (United States)

^e FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

Author keywords

Energy metabolism; Exercise; Gut barrier; Metabolomics; Microbiology

Indexed keywords

BRANCHED CHAIN AMINO ACID; C REACTIVE PROTEIN; CREATINE KINASE; CYSTEINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; AUTACOID; CARBOHYDRATE DIET; PROTEIN INTAKE;

ADULT; ARTICLE; BACTERIAL METABOLISM; BACTERIAL MICROBIOME; BACTEROIDES; BLOOD BIOCHEMISTRY; BODY MASS; BODY WEIGHT; CALORIC INTAKE; CARBOHYDRATE INTAKE; CHEMICAL COMPOSITION; DNA EXTRACTION; DNA ISOLATION; DYNAMICS; ELECTROSPRAY; ENERGY EXPENDITURE; ENERGY METABOLISM; FATTY ACID OXIDATION; FECES ANALYSIS; FEMALE; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; INFLAMMATION; INTESTINAL MICROBIOTA COMPOSITION; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; METABOLITE; METABOLOME; METABOLOMICS; PERMEABILITY; PH; PHYSIOLOGICAL STRESS; PRIORITY JOURNAL; PROTEIN INTAKE; STEROID METABOLISM; SYSTEMS BIOLOGY; TRAINING; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINE SAMPLING; YOUNG ADULT; ADMINISTRATION AND DOSAGE; ADOLESCENT; AGE; BACTERIUM; BLOOD; CARBOHYDRATE DIET; COMPARATIVE STUDY; CONTROLLED STUDY; ENDURANCE; FECES; HOST PATHOGEN INTERACTION; INTESTINE; INTESTINE ABSORPTION; METABOLISM; MICROBIOLOGY; MILITARY MEDICINE; NORWAY; NUTRITIONAL STATUS; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; TIME FACTOR;

ADOLESCENT; AGE FACTORS; BACTERIA; DIETARY CARBOHYDRATES; DIETARY PROTEINS; ENERGY METABOLISM; FECES; FEMALE; GASTROINTESTINAL MICROBIOME; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION MEDIATORS; INTESTINAL ABSORPTION; INTESTINES; MALE; METABOLOMICS; MILITARY MEDICINE; NORWAY; NUTRITIONAL STATUS; PERMEABILITY; PHYSICAL ENDURANCE; STRESS, PHYSIOLOGICAL; SYSTEMS BIOLOGY; TIME FACTORS; YOUNG ADULT;

EID: 85020167503     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00066.2017     Document Type: Article

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