Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1-1 isoform outside paraspeckles

RNA

Volumn 23, Issue 6, 2017, Pages 872-881

  Li, Ruohan ^a   Harvey, Alan R ^a,b   Hodgetts, Stuart I ^a,b   Fox, Archa H ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b Western Australian Biomedical Research Institute   (Australia)

Author keywords

CRISPR genome editing; DBHS proteins; Long noncoding RNAs; NEAT1; Paraspeckles

Indexed keywords

DBHS PROTEIN; LONG UNTRANSLATED RNA; NUCLEAR PARASPECKLE ASSEMBLY TRANSCRIPT 1; PROTEIN; UNCLASSIFIED DRUG; GUIDE RNA; NEAT1 LONG NON-CODING RNA, HUMAN; RNA ISOFORM; RNA SPLICING FACTOR;

ALLELE; ARTICLE; CHROMATIN; CONTROLLED STUDY; CRISPR CAS SYSTEM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DISRUPTION; GENE EDITING; GENE FUNCTION; GENE LOCATION; GENE STRUCTURE; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; POLYADENYLATION; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; TRANSCRIPTION INITIATION SITE; U2OS CELL LINE; CELL LINE; CELL NUCLEUS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENE INACTIVATION; GENETICS; METABOLISM; RNA TRANSPORT;

CELL LINE; CELL NUCLEUS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; GENE EDITING; GENE KNOCKOUT TECHNIQUES; HUMANS; RNA ISOFORMS; RNA SPLICING FACTORS; RNA TRANSPORT; RNA, GUIDE; RNA, LONG NONCODING;

EID: 85019931572     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.059477.116     Document Type: Article

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