메뉴 건너뛰기




Volumn 8, Issue 6, 2017, Pages 401-409

The roles of bile acids and applications of microencapsulation technology in treating Type 1 diabetes mellitus

Author keywords

bile acids; diabetes mellitus; inflammation; microencapsulation; cells

Indexed keywords

BILE ACID; GLUCOSE;

EID: 85019921810     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde-2017-0010     Document Type: Review
Times cited : (17)

References (86)
  • 1
    • 84964284549 scopus 로고    scopus 로고
    • An advanced microencapsulated system: A platform for optimized oral delivery of antidiabetic drug-bile acid formulations
    • Mooranian A, Negrulj R, Mathavan S et al. An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations. Pharm. Dev. Technol. 20(6), 702-709 (2015).
    • (2015) Pharm. Dev. Technol. , vol.20 , Issue.6 , pp. 702-709
    • Mooranian, A.1    Negrulj, R.2    Mathavan, S.3
  • 2
    • 77449160891 scopus 로고    scopus 로고
    • Historical keyword: Diabetes
    • Barnett R. Historical keyword: diabetes. Lancet 375(9710), 191 (2010).
    • (2010) Lancet , vol.375 , Issue.9710 , pp. 191
    • Barnett, R.1
  • 3
    • 0037219411 scopus 로고    scopus 로고
    • Beta-cell deficit and increased beta-cell apoptosis in humans with Type 2 diabetes
    • Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with Type 2 diabetes. Diabetes 52(1), 102-110 (2003).
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 102-110
    • Butler, A.E.1    Janson, J.2    Bonner-Weir, S.3    Ritzel, R.4    Rizza, R.A.5    Butler, P.C.6
  • 4
    • 84905247136 scopus 로고    scopus 로고
    • Potentials and limitations of bile acids in type 2 diabetes mellitus: Applications of microencapsulation as a novel oral delivery system
    • Negrulj R, Mooranian A, Al-Salami H. Potentials and limitations of bile acids in type 2 diabetes mellitus: applications of microencapsulation as a novel oral delivery system. J. Endocrinol. Diabetes Mellit. 1(2), 49-59 (2013).
    • (2013) J. Endocrinol. Diabetes Mellit. , vol.1 , Issue.2 , pp. 49-59
    • Negrulj, R.1    Mooranian, A.2    Al-Salami, H.3
  • 5
    • 33847611626 scopus 로고    scopus 로고
    • Insulin resistance, the metabolic syndrome, and complication risk in Type 1 diabetes: 'Double diabetes' in the diabetes control and complications trial
    • Kilpatrick ES, Rigby AS, Atkin SL. Insulin resistance, the metabolic syndrome, and complication risk in Type 1 diabetes: 'Double diabetes' in the diabetes control and complications trial. Diabetes Care 30(3), 707-712 (2007).
    • (2007) Diabetes Care , vol.30 , Issue.3 , pp. 707-712
    • Kilpatrick, E.S.1    Rigby, A.S.2    Atkin, S.L.3
  • 7
    • 84874651768 scopus 로고    scopus 로고
    • Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases
    • Duboc H, Rajca S, Rainteau D et al. Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases. Gut 62(4), 531-539 (2013).
    • (2013) Gut , vol.62 , Issue.4 , pp. 531-539
    • Duboc, H.1    Rajca, S.2    Rainteau, D.3
  • 8
    • 18844434370 scopus 로고    scopus 로고
    • Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease
    • Chong ZZ, Li F, Maiese K. Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Prog. Neurobiol. 75(3), 207-246 (2005).
    • (2005) Prog. Neurobiol. , vol.75 , Issue.3 , pp. 207-246
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 9
    • 84921456608 scopus 로고    scopus 로고
    • HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death
    • Peng S, Zhao S, Yan F et al. HDAC2 selectively regulates FOXO3a-mediated gene transcription during oxidative stress-induced neuronal cell death. J. Neurosci. 35(3), 1250-1259 (2015).
    • (2015) J. Neurosci. , vol.35 , Issue.3 , pp. 1250-1259
    • Peng, S.1    Zhao, S.2    Yan, F.3
  • 10
    • 79958157501 scopus 로고    scopus 로고
    • Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells
    • Booth DM, Murphy JA, Mukherjee R et al. Reactive oxygen species induced by bile acid induce apoptosis and protect against necrosis in pancreatic acinar cells. Gastroenterology 140(7), 2116-2125 (2011).
    • (2011) Gastroenterology , vol.140 , Issue.7 , pp. 2116-2125
    • Booth, D.M.1    Murphy, J.A.2    Mukherjee, R.3
  • 11
    • 33645738747 scopus 로고    scopus 로고
    • Endocrine functions of bile acids
    • Houten S, Watanabe M, Auwerx J. Endocrine functions of bile acids. EMBO J. 25(7), 1419-1425 (2006).
    • (2006) EMBO J. , vol.25 , Issue.7 , pp. 1419-1425
    • Houten, S.1    Watanabe, M.2    Auwerx, J.3
  • 12
    • 0033470181 scopus 로고    scopus 로고
    • Bile acids: The good, the bad, and the ugly
    • Hofmann AF. Bile acids: the good, the bad, and the ugly. News Physiol. Sci. 14(1), 24-29 (1999).
    • (1999) News Physiol. Sci. , vol.14 , Issue.1 , pp. 24-29
    • Hofmann, A.F.1
  • 14
    • 77953913586 scopus 로고    scopus 로고
    • Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
    • Wu HJ, Ivanov II, Darce J et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 32(6), 815-827 (2010).
    • (2010) Immunity , vol.32 , Issue.6 , pp. 815-827
    • Wu, H.J.1    Ivanov, I.I.2    Darce, J.3
  • 15
    • 0018126331 scopus 로고
    • Bile lipid composition and bile acid pool size in diabetes
    • De Leon M, Ferenderes R, Carulli N. Bile lipid composition and bile acid pool size in diabetes. Am. J. Dig. Dis. 23(8), 710-716 (1978).
    • (1978) Am. J. Dig. Dis. , vol.23 , Issue.8 , pp. 710-716
    • De Leon, M.1    Ferenderes, R.2    Carulli, N.3
  • 16
    • 0019202486 scopus 로고
    • Effect of diabetes during pregnancy on maternal and neonatal bile acid metabolism in the rat
    • Hassan AS, Subbiah MT. Effect of diabetes during pregnancy on maternal and neonatal bile acid metabolism in the rat. Proc. Soc. Exp. Biol. Med. 165(3), 490-495 (1980).
    • (1980) Proc. Soc. Exp. Biol. Med. , vol.165 , Issue.3 , pp. 490-495
    • Hassan, A.S.1    Subbiah, M.T.2
  • 17
    • 0019186993 scopus 로고
    • Unidirectional flux rate of cholesterol and fatty acids into the intestine of rats with drug-induced diabetes mellitus: Effect of variations in the effective resistance of the unstirred water layer and the bile acid micelle
    • Thomson AB. Unidirectional flux rate of cholesterol and fatty acids into the intestine of rats with drug-induced diabetes mellitus: effect of variations in the effective resistance of the unstirred water layer and the bile acid micelle. J. Lipid Res. 21(6), 687-698 (1980).
    • (1980) J. Lipid Res. , vol.21 , Issue.6 , pp. 687-698
    • Thomson, A.B.1
  • 18
    • 77956342528 scopus 로고    scopus 로고
    • Bile acid toxicity structure-activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A)
    • Sharma R, Majer F, Peta VK et al. Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A). Bioorg. Med. Chem. 18(18), 6886-6895 (2010).
    • (2010) Bioorg. Med. Chem. , vol.18 , Issue.18 , pp. 6886-6895
    • Sharma, R.1    Majer, F.2    Peta, V.K.3
  • 19
    • 27544431934 scopus 로고    scopus 로고
    • Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes
    • Dent P, Han SI, Mitchell C et al. Inhibition of insulin/IGF-1 receptor signaling enhances bile acid toxicity in primary hepatocytes. Biochem. Pharmacol. 70(11), 1685-1696 (2005).
    • (2005) Biochem. Pharmacol. , vol.70 , Issue.11 , pp. 1685-1696
    • Dent, P.1    Han, S.I.2    Mitchell, C.3
  • 20
    • 84880907693 scopus 로고    scopus 로고
    • The bile acid membrane receptor TGR5: A novel pharmacological target in metabolic, inflammatory and neoplastic disorders
    • Stepanov V, Stankov K, Mikov M. The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders. J. Recept. Signal. Transduct. Res. 33(4), 213-223 (2013).
    • (2013) J. Recept. Signal. Transduct. Res. , vol.33 , Issue.4 , pp. 213-223
    • Stepanov, V.1    Stankov, K.2    Mikov, M.3
  • 21
    • 82255163544 scopus 로고    scopus 로고
    • Microencapsulation using vibrating technology
    • Whelehan M, Marison IW. Microencapsulation using vibrating technology. J. Microencapsul. 28(8), 669-688 (2011).
    • (2011) J. Microencapsul. , vol.28 , Issue.8 , pp. 669-688
    • Whelehan, M.1    Marison, I.W.2
  • 22
    • 84925494096 scopus 로고    scopus 로고
    • Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes
    • Ehses JA, Donath MY. Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes. Diabetologia 58(3), 425-428 (2015).
    • (2015) Diabetologia , vol.58 , Issue.3 , pp. 425-428
    • Ehses, J.A.1    Donath, M.Y.2
  • 23
    • 0037341759 scopus 로고    scopus 로고
    • Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels
    • Hansen TK, Thiel S, Wouters PJ, Christiansen JS, Van den Berghe G. Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J. Clin. Endocrinol. Metab. 88(3), 1082-1088 (2003).
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , Issue.3 , pp. 1082-1088
    • Hansen, T.K.1    Thiel, S.2    Wouters, P.J.3    Christiansen, J.S.4    Van Den Berghe, G.5
  • 24
    • 67649364114 scopus 로고    scopus 로고
    • The role of inflammation in insulitis and beta-cell loss in Type 1 diabetes
    • Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and beta-cell loss in Type 1 diabetes. Nat. Rev. Endocrinol. 5(4), 219-226 (2009).
    • (2009) Nat. Rev. Endocrinol. , vol.5 , Issue.4 , pp. 219-226
    • Eizirik, D.L.1    Colli, M.L.2    Ortis, F.3
  • 25
    • 33644756809 scopus 로고    scopus 로고
    • Increased monocytic activity and biomarkers of inflammation in patients with Type 1 diabetes
    • Devaraj S, Glaser N, Griffen S, Wang-Polagruto J, Miguelino E, Jialal I. Increased monocytic activity and biomarkers of inflammation in patients with Type 1 diabetes. Diabetes 55(3), 774-779 (2006).
    • (2006) Diabetes , vol.55 , Issue.3 , pp. 774-779
    • Devaraj, S.1    Glaser, N.2    Griffen, S.3    Wang-Polagruto, J.4    Miguelino, E.5    Jialal, I.6
  • 26
    • 0037365579 scopus 로고    scopus 로고
    • Altered glycosylation of alpha1-acid glycoprotein in patients with inflammation and diabetes mellitus
    • Higai K, Azuma Y, Aoki Y, Matsumoto K. Altered glycosylation of alpha1-acid glycoprotein in patients with inflammation and diabetes mellitus. Clin. Chim. Acta 329(1-2), 117-125 (2003).
    • (2003) Clin. Chim. Acta , vol.329 , Issue.1-2 , pp. 117-125
    • Higai, K.1    Azuma, Y.2    Aoki, Y.3    Matsumoto, K.4
  • 27
    • 0030891456 scopus 로고    scopus 로고
    • Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats
    • Kullmann F, Gross V, Ruschoff J et al. Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats. Z. Gastroenterol. 35(3), 171-178 (1997).
    • (1997) Z. Gastroenterol. , vol.35 , Issue.3 , pp. 171-178
    • Kullmann, F.1    Gross, V.2    Ruschoff, J.3
  • 28
    • 84873019964 scopus 로고    scopus 로고
    • Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis
    • Martinez-Moya P, Romero-Calvo I, Requena P et al. Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis. Int. Immunopharmacol. 15(2), 372-380 (2013).
    • (2013) Int. Immunopharmacol. , vol.15 , Issue.2 , pp. 372-380
    • Martinez-Moya, P.1    Romero-Calvo, I.2    Requena, P.3
  • 29
    • 84940555342 scopus 로고    scopus 로고
    • The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: Potential applications in diabetes: A characterization study
    • Mooranian A, Negrulj R, Arfuso F, Al-Salami H. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv. Transl. Res. 5(5), 511-522 (2015).
    • (2015) Drug Deliv. Transl. Res. , vol.5 , Issue.5 , pp. 511-522
    • Mooranian, A.1    Negrulj, R.2    Arfuso, F.3    Al-Salami, H.4
  • 30
    • 85008945735 scopus 로고    scopus 로고
    • Effects of acute dietary weight loss on postprandial plasma bile acid responses in obese insulin resistant subjects
    • Epub ahead of print
    • Van Nierop FS, Kulik W, Endert E et al. Effects of acute dietary weight loss on postprandial plasma bile acid responses in obese insulin resistant subjects. Clin. Nutr. doi:10.1016/j. clnu.2016.10.006 (2016) (Epub ahead of print).
    • (2016) Clin. Nutr
    • Van Nierop, F.S.1    Kulik, W.2    Endert, E.3
  • 31
    • 33751518777 scopus 로고    scopus 로고
    • Chemistry, biosynthesis, analysis, chemical & metabolic transformations and pharmacology
    • Mikov M, Fawcett JP. Chemistry, biosynthesis, analysis, chemical & metabolic transformations and pharmacology. Eur. J. Drug. Metab. Pharmacokinet. 31(3), 133-134 (2006).
    • (2006) Eur. J. Drug. Metab. Pharmacokinet. , vol.31 , Issue.3 , pp. 133-134
    • Mikov, M.1    Fawcett, J.P.2
  • 32
    • 33751518532 scopus 로고    scopus 로고
    • Pharmacology of bile acids and their derivatives: Absorption promoters and therapeutic agents
    • Mikov M, Fawcett JP, Kuhajda K, Kevresan S. Pharmacology of bile acids and their derivatives: absorption promoters and therapeutic agents. Eur. J. Drug. Metab. Pharmacokinet. 31(3), 237-251 (2006).
    • (2006) Eur. J. Drug. Metab. Pharmacokinet. , vol.31 , Issue.3 , pp. 237-251
    • Mikov, M.1    Fawcett, J.P.2    Kuhajda, K.3    Kevresan, S.4
  • 34
    • 0019469729 scopus 로고
    • Biliary lipid and bile acid composition in insulin-dependent diabetes mellitus. Arguments for increased intestinal bacterial bile acid degradation
    • Meinders AE, Van Berge Henegouwen GP, Willekens FL, Schwerzel AL, Ruben A, Huybregts AW. Biliary lipid and bile acid composition in insulin-dependent diabetes mellitus. Arguments for increased intestinal bacterial bile acid degradation. Dig. Dis. Sci. 26(5), 402-408 (1981).
    • (1981) Dig. Dis. Sci. , vol.26 , Issue.5 , pp. 402-408
    • Meinders, A.E.1    Van Berge Henegouwen, G.P.2    Willekens, F.L.3    Schwerzel, A.L.4    Ruben, A.5    Huybregts, A.W.6
  • 35
    • 84905730484 scopus 로고    scopus 로고
    • Pharmacokinetics and hypoglycaemic effect of 3 alpha, 7 alpha-dihydroxy-12-oxo-5beta-cholanate (MKC) in diabetic rat
    • Mikov M, Boni NS, Al-Salami H, Kuhajda K, Kevresan S, Fawcett JP. Pharmacokinetics and hypoglycaemic effect of 3 alpha, 7 alpha-dihydroxy-12-oxo-5beta-cholanate (MKC) in diabetic rat. FEBS J. 273, 210 (2006).
    • (2006) FEBS J. , vol.273 , pp. 210
    • Mikov, M.1    Boni, N.S.2    Al-Salami, H.3    Kuhajda, K.4    Kevresan, S.5    Fawcett, J.P.6
  • 36
    • 44349117768 scopus 로고    scopus 로고
    • Bile acids: A bitter sweet remedy for diabetes
    • Al-Salami H, Kansara H, King J et al. Bile acids: a bitter sweet remedy for diabetes. New Zealand Pharm. J. 27(10), 17-20 (2007).
    • (2007) New Zealand Pharm. J. , vol.27 , Issue.10 , pp. 17-20
    • Al-Salami, H.1    Kansara, H.2    King, J.3
  • 37
    • 34247475593 scopus 로고    scopus 로고
    • Bioavailability and hypoglycemic activity of the semisynthetic bile acid salt, sodium 3alpha, 7alpha-dihydroxy-12-oxo-5beta-cholanate, in healthy and diabetic rats
    • Mikov M, Boni NS, Al-Salami H et al. Bioavailability and hypoglycemic activity of the semisynthetic bile acid salt, sodium 3alpha, 7alpha-dihydroxy-12-oxo-5beta-cholanate, in healthy and diabetic rats. Eur. J. Drug Metab. Pharmacokinet. 32(1), 7-12 (2007).
    • (2007) Eur. J. Drug Metab. Pharmacokinet. , vol.32 , Issue.1 , pp. 7-12
    • Mikov, M.1    Boni, N.S.2    Al-Salami, H.3
  • 38
    • 44349086349 scopus 로고    scopus 로고
    • Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics
    • Al-Salami H, Butt G, Tucker I, Mikov M. Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics. Methods Find. Exp. Clin. Pharmacol. 30(2), 107-113 (2008).
    • (2008) Methods Find. Exp. Clin. Pharmacol. , vol.30 , Issue.2 , pp. 107-113
    • Al-Salami, H.1    Butt, G.2    Tucker, I.3    Mikov, M.4
  • 39
    • 84964378826 scopus 로고    scopus 로고
    • Bile acids and probiotics could help treating diabetes
    • Calasan J, Al-Salami H, Mikov M. Bile acids and probiotics could help treating diabetes. FEBS J. 279, 267-268 (2012).
    • (2012) FEBS J. , vol.279 , pp. 267-268
    • Calasan, J.1    Al-Salami, H.2    Mikov, M.3
  • 40
    • 79955731167 scopus 로고    scopus 로고
    • EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3beta, and beta-catenin to foster vascular integrity during experimental diabetes
    • Chong ZZ, Hou J, Shang YC, Wang S, Maiese K. EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3beta, and beta-catenin to foster vascular integrity during experimental diabetes. Curr. Neurovasc. Res. 8(2), 103-120 (2011).
    • (2011) Curr. Neurovasc. Res. , vol.8 , Issue.2 , pp. 103-120
    • Chong, Z.Z.1    Hou, J.2    Shang, Y.C.3    Wang, S.4    Maiese, K.5
  • 41
    • 84867507033 scopus 로고    scopus 로고
    • Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy
    • Fu D, Wu M, Zhang J et al. Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy. Diabetologia 55(11), 3128-3140 (2012).
    • (2012) Diabetologia , vol.55 , Issue.11 , pp. 3128-3140
    • Fu, D.1    Wu, M.2    Zhang, J.3
  • 42
    • 84857775690 scopus 로고    scopus 로고
    • Bile acid signaling in liver metabolism and diseases
    • Epub ahead of print
    • Li T, Chiang JY. Bile acid signaling in liver metabolism and diseases. J. Lipids 754067 doi:10.1155/2012/754067 ( (2012) () (Epub ahead of print).).
    • (2012) J. Lipids , pp. 754067
    • Li, T.1    Chiang, J.Y.2
  • 43
    • 79955890870 scopus 로고    scopus 로고
    • Bile acid metabolism and the pathogenesis of Type 2 diabetes
    • Prawitt J, Caron S, Staels B. Bile acid metabolism and the pathogenesis of Type 2 diabetes. Curr. Diab. Rep. 11(3), 160-166 (2011).
    • (2011) Curr. Diab. Rep. , vol.11 , Issue.3 , pp. 160-166
    • Prawitt, J.1    Caron, S.2    Staels, B.3
  • 44
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol. Rev. 89(1), 147-191 (2009).
    • (2009) Physiol. Rev. , vol.89 , Issue.1 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 46
    • 84860225393 scopus 로고    scopus 로고
    • Cytochrome P450s in the synthesis of cholesterol and bile acids - From mouse models to human diseases
    • Lorbek G, Lewinska M, Rozman D. Cytochrome P450s in the synthesis of cholesterol and bile acids - from mouse models to human diseases. FEBS J. 279(9), 1516-1533 (2012).
    • (2012) FEBS J. , vol.279 , Issue.9 , pp. 1516-1533
    • Lorbek, G.1    Lewinska, M.2    Rozman, D.3
  • 47
    • 79959525960 scopus 로고    scopus 로고
    • The bile acid membrane receptor TGR5: A valuable metabolic target
    • Pols TW, Noriega LG, Nomura M, Auwerx J, Schoonjans K. The bile acid membrane receptor TGR5: a valuable metabolic target. Dig. Dis. 29(1), 37-44 (2011).
    • (2011) Dig. Dis. , vol.29 , Issue.1 , pp. 37-44
    • Pols, T.W.1    Noriega, L.G.2    Nomura, M.3    Auwerx, J.4    Schoonjans, K.5
  • 48
    • 0016765162 scopus 로고
    • Dissolution of cholesterol gallstones by long-term administration of ursodeoxycholic acid
    • Makino I, Shinozaki K, Yoshino K, Nakagawa S. Dissolution of cholesterol gallstones by long-term administration of ursodeoxycholic acid. Nihon Shokakibyo Gakkai Zasshi 72(6), 690-702 (1975).
    • (1975) Nihon Shokakibyo Gakkai Zasshi , vol.72 , Issue.6 , pp. 690-702
    • Makino, I.1    Shinozaki, K.2    Yoshino, K.3    Nakagawa, S.4
  • 49
    • 0017643827 scopus 로고
    • Effects of diabetes mellitus on cholesterol metabolism in man
    • Bennion LJ, Grundy SM. Effects of diabetes mellitus on cholesterol metabolism in man. N. Engl. J. Med. 296(24), 1365-1371 (1977).
    • (1977) N. Engl. J. Med. , vol.296 , Issue.24 , pp. 1365-1371
    • Bennion, L.J.1    Grundy, S.M.2
  • 50
    • 0019935179 scopus 로고
    • Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus
    • Abrams JJ, Ginsberg H, Grundy SM. Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus. Diabetes 31(10), 903-910 (1982).
    • (1982) Diabetes , vol.31 , Issue.10 , pp. 903-910
    • Abrams, J.J.1    Ginsberg, H.2    Grundy, S.M.3
  • 53
    • 56149126257 scopus 로고    scopus 로고
    • Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: New insights into hepatic inflammation
    • Wagner M, Zollner G, Trauner M. Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation. Hepatology 48(5), 1383-1386 (2008).
    • (2008) Hepatology , vol.48 , Issue.5 , pp. 1383-1386
    • Wagner, M.1    Zollner, G.2    Trauner, M.3
  • 54
    • 0020079894 scopus 로고
    • Differing effects of ursodeoxycholic or chenodeoxycholic acid on biliary cholesterol saturation and bile acid metabolism in man. A dose-response study
    • Thistle JL, Larusso NF, Hofmann AF, Turcotte J, Carlson GL, Ott BJ. Differing effects of ursodeoxycholic or chenodeoxycholic acid on biliary cholesterol saturation and bile acid metabolism in man. A dose-response study. Dig. Dis. Sci. 27(2), 161-168 (1982).
    • (1982) Dig. Dis. Sci. , vol.27 , Issue.2 , pp. 161-168
    • Thistle, J.L.1    Larusso, N.F.2    Hofmann, A.F.3    Turcotte, J.4    Carlson, G.L.5    Ott, B.J.6
  • 55
    • 0019181347 scopus 로고
    • Specific changes of bile acid metabolism in spontaneously diabetic Wistar rats
    • Hassan AS, Subbiah MT, Thiebert P. Specific changes of bile acid metabolism in spontaneously diabetic Wistar rats. Proc. Soc. Exp. Biol. Med. 164(4), 449-452 (1980).
    • (1980) Proc. Soc. Exp. Biol. Med. , vol.164 , Issue.4 , pp. 449-452
    • Hassan, A.S.1    Subbiah, M.T.2    Thiebert, P.3
  • 56
    • 0019496764 scopus 로고
    • Effect of maternal diabetes on fetal bile acid metabolism in the rat
    • Hassan AS, Hedeen K, Subbiah MT. Effect of maternal diabetes on fetal bile acid metabolism in the rat. Biochem. Med. 25(2), 168-173 (1981).
    • (1981) Biochem. Med. , vol.25 , Issue.2 , pp. 168-173
    • Hassan, A.S.1    Hedeen, K.2    Subbiah, M.T.3
  • 57
    • 0016195836 scopus 로고
    • Studies on cholesterol metabolism in the diabetic rat
    • Nervi FO, Gonzalez A, Valdivieso VD. Studies on cholesterol metabolism in the diabetic rat. Metabolism 23(6), 495-503 (1974).
    • (1974) Metabolism , vol.23 , Issue.6 , pp. 495-503
    • Nervi, F.O.1    Gonzalez, A.2    Valdivieso, V.D.3
  • 58
    • 0021240675 scopus 로고
    • Effect of streptozotocin-induced diabetes in neonatal rat on bile acid pool changes in adult life: Selective sensitivity in females
    • Wey HE, Yunker RL, Harris P, Subbiah MT. Effect of streptozotocin-induced diabetes in neonatal rat on bile acid pool changes in adult life: selective sensitivity in females. Biochem. Med. 31(2), 167-173 (1984).
    • (1984) Biochem. Med. , vol.31 , Issue.2 , pp. 167-173
    • Wey, H.E.1    Yunker, R.L.2    Harris, P.3    Subbiah, M.T.4
  • 59
    • 0036086885 scopus 로고    scopus 로고
    • Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats
    • van Waarde WM, Verkade HJ, Wolters H et al. Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats. Gastroenterology 122(7), 1842-1852 (2002).
    • (2002) Gastroenterology , vol.122 , Issue.7 , pp. 1842-1852
    • Van Waarde, W.M.1    Verkade, H.J.2    Wolters, H.3
  • 60
    • 33847057732 scopus 로고    scopus 로고
    • Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin
    • Kobayashi M, Ikegami H, Fujisawa T et al. Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin. Diabetes 56(1), 239-247 (2007).
    • (2007) Diabetes , vol.56 , Issue.1 , pp. 239-247
    • Kobayashi, M.1    Ikegami, H.2    Fujisawa, T.3
  • 61
    • 34347401852 scopus 로고    scopus 로고
    • Bile acid sequestrants and the treatment of Type 2 diabetes mellitus
    • Staels B, Kuipers F. Bile acid sequestrants and the treatment of Type 2 diabetes mellitus. Drugs 67(10), 1383-1392 (2007).
    • (2007) Drugs , vol.67 , Issue.10 , pp. 1383-1392
    • Staels, B.1    Kuipers, F.2
  • 62
    • 33645738747 scopus 로고    scopus 로고
    • Endocrine functions of bile acids
    • Houten SM, Watanabe M, Auwerx J. Endocrine functions of bile acids. EMBO J. 25(7), 1419-1425 (2006).
    • (2006) EMBO J. , vol.25 , Issue.7 , pp. 1419-1425
    • Houten, S.M.1    Watanabe, M.2    Auwerx, J.3
  • 63
    • 67349112373 scopus 로고    scopus 로고
    • Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model
    • Roesch LF, Lorca GL, Casella G et al. Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model. ISME J. 3(5), 536-548 (2009).
    • (2009) ISME J. , vol.3 , Issue.5 , pp. 536-548
    • Roesch, L.F.1    Lorca, G.L.2    Casella, G.3
  • 64
    • 84855174371 scopus 로고    scopus 로고
    • Gut bacteria may override genetic protections against diabetes
    • Meadows R. Gut bacteria may override genetic protections against diabetes. PLoS Biol. 9(12), e1001215 (2011).
    • (2011) PLoS Biol. , vol.9 , Issue.12 , pp. e1001215
    • Meadows, R.1
  • 65
    • 0025944991 scopus 로고
    • Diabetes-induced bile acid composition changes in rat bile determined by high performance liquid chromatography
    • Siow Y, Schurr A, Vitale GC. Diabetes-induced bile acid composition changes in rat bile determined by high performance liquid chromatography. Life Sci. 49(18), 1301-1308 (1991).
    • (1991) Life Sci. , vol.49 , Issue.18 , pp. 1301-1308
    • Siow, Y.1    Schurr, A.2    Vitale, G.C.3
  • 66
    • 0018139252 scopus 로고
    • Bile acid pool changes and regulation of cholate synthesis in experimental diabetes
    • Nervi FO, Severin CH, Valdivieso VD. Bile acid pool changes and regulation of cholate synthesis in experimental diabetes. Biochim. Biophys. Acta 529(2), 212-223 (1978).
    • (1978) Biochim. Biophys. Acta , vol.529 , Issue.2 , pp. 212-223
    • Nervi, F.O.1    Severin, C.H.2    Valdivieso, V.D.3
  • 67
    • 83455243025 scopus 로고    scopus 로고
    • Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes
    • Chen L, Yao X, Young A et al. Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes. Am. J. Physiol. Endocrinol. Metab. 302(1), E68-E76 (2012).
    • (2012) Am. J. Physiol. Endocrinol. Metab. , vol.302 , Issue.1 , pp. E68-E76
    • Chen, L.1    Yao, X.2    Young, A.3
  • 68
    • 33846958795 scopus 로고    scopus 로고
    • Effect of rat pretreatment with aqueous solutions of stevioside and bile acids on the action of certain cardioactive drugs
    • Vasovic V, Vukmirovic S, Posa M, Mikov M, Raskovic A, Jakovljevic V. Effect of rat pretreatment with aqueous solutions of stevioside and bile acids on the action of certain cardioactive drugs. Eur. J. Drug Metab. Pharmacokinet. 31(4), 311-314 (2006).
    • (2006) Eur. J. Drug Metab. Pharmacokinet. , vol.31 , Issue.4 , pp. 311-314
    • Vasovic, V.1    Vukmirovic, S.2    Posa, M.3    Mikov, M.4    Raskovic, A.5    Jakovljevic, V.6
  • 69
    • 0020573365 scopus 로고
    • Uptake of bile acids into rat intestine
    • Thomson AB. Uptake of bile acids into rat intestine. Effect of diabetes mellitus. Diabetes 32(10), 900-907 (1983).
    • (1983) Effect of Diabetes Mellitus. Diabetes , vol.32 , Issue.10 , pp. 900-907
    • Thomson, A.B.1
  • 70
    • 34249691888 scopus 로고    scopus 로고
    • Protective effect of ursodeoxycholic acid on liver mitochondrial function in rats with alloxan-induced diabetes: Link with oxidative stress
    • Lukivskaya O, Patsenker E, Buko VU. Protective effect of ursodeoxycholic acid on liver mitochondrial function in rats with alloxan-induced diabetes: link with oxidative stress. Life Sci. 80(26), 2397-2402 (2007).
    • (2007) Life Sci. , vol.80 , Issue.26 , pp. 2397-2402
    • Lukivskaya, O.1    Patsenker, E.2    Buko, V.U.3
  • 71
    • 84876248677 scopus 로고    scopus 로고
    • Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans
    • Wu T, Bound MJ, Standfield SD, Jones KL, Horowitz M, Rayner CK. Effects of taurocholic acid on glycemic, glucagon-like peptide-1, and insulin responses to small intestinal glucose infusion in healthy humans. J. Clin. Endocrinol. Metab. 98(4), E718-E722 (2013).
    • (2013) J. Clin. Endocrinol. Metab. , vol.98 , Issue.4 , pp. E718-E722
    • Wu, T.1    Bound, M.J.2    Standfield, S.D.3    Jones, K.L.4    Horowitz, M.5    Rayner, C.K.6
  • 72
    • 77955411159 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
    • Kars M, Yang L, Gregor MF et al. Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes 59(8), 1899-1905 (2010).
    • (2010) Diabetes , vol.59 , Issue.8 , pp. 1899-1905
    • Kars, M.1    Yang, L.2    Gregor, M.F.3
  • 73
    • 18844405709 scopus 로고    scopus 로고
    • Effect of intensive glycemic control on levels of markers of inflammation in Type 1 diabetes mellitus in the diabetes control and complications trial
    • Schaumberg DA, Glynn RJ, Jenkins AJ et al. Effect of intensive glycemic control on levels of markers of inflammation in Type 1 diabetes mellitus in the diabetes control and complications trial. Circulation 111(19), 2446-2453 (2005).
    • (2005) Circulation , vol.111 , Issue.19 , pp. 2446-2453
    • Schaumberg, D.A.1    Glynn, R.J.2    Jenkins, A.J.3
  • 74
    • 0142197612 scopus 로고    scopus 로고
    • Regulation of IL4 gene expression by T cells and therapeutic perspectives
    • Li-Weber M, Krammer PH. Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat. Rev. Immunol. 3(7), 534-543 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , Issue.7 , pp. 534-543
    • Li-Weber, M.1    Krammer, P.H.2
  • 76
  • 78
  • 80
    • 9144263544 scopus 로고    scopus 로고
    • History, challenges and perspectives of cell microencapsulation
    • Orive G, Hernandez RM, Rodriguez Gascon A et al. History, challenges and perspectives of cell microencapsulation. Trends Biotechnol. 22(2), 87-92 (2004).
    • (2004) Trends Biotechnol. , vol.22 , Issue.2 , pp. 87-92
    • Orive, G.1    Hernandez, R.M.2    Rodriguez Gascon, A.3
  • 81
    • 84908071946 scopus 로고    scopus 로고
    • Microencapsulation as a novel delivery method for the potential antidiabetic drug, probucol
    • Mooranian A, Negrulj R, Chen-Tan N et al. Microencapsulation as a novel delivery method for the potential antidiabetic drug, probucol. Drug Des. Devel. Ther. 8, 1221-1230 (2014).
    • (2014) Drug Des. Devel. Ther. , vol.8 , pp. 1221-1230
    • Mooranian, A.1    Negrulj, R.2    Chen-Tan, N.3
  • 82
    • 0036252498 scopus 로고    scopus 로고
    • Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment
    • Chung TW, Yang J, Akaike T et al. Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment. Biomaterials 23(14), 2827-2834 (2002).
    • (2002) Biomaterials , vol.23 , Issue.14 , pp. 2827-2834
    • Chung, T.W.1    Yang, J.2    Akaike, T.3
  • 83
    • 0042061223 scopus 로고    scopus 로고
    • Hydrogels for tissue engineering: Scaffold design variables and applications
    • Drury JL, Mooney DJ. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 24(24), 4337-4351 (2003).
    • (2003) Biomaterials , vol.24 , Issue.24 , pp. 4337-4351
    • Drury, J.L.1    Mooney, D.J.2
  • 84
    • 33746474818 scopus 로고    scopus 로고
    • Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan - A review
    • George M, Abraham TE. Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan - a review. J. Control. Release 114(1), 1-14 (2006).
    • (2006) J. Control. Release , vol.114 , Issue.1 , pp. 1-14
    • George, M.1    Abraham, T.E.2
  • 85
    • 84908066377 scopus 로고    scopus 로고
    • An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer
    • Mooranian A, Negrulj R, Chen-Tan N, Watts GF, Arfuso F, Al-Salami H. An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer. Drug Des. Devel. Ther. 8, 1673-1683 (2014).
    • (2014) Drug Des. Devel. Ther. , vol.8 , pp. 1673-1683
    • Mooranian, A.1    Negrulj, R.2    Chen-Tan, N.3    Watts, G.F.4    Arfuso, F.5    Al-Salami, H.6
  • 86
    • 84905244183 scopus 로고    scopus 로고
    • Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: A characterization study
    • Mooranian A, Negrulj R, Chen-Tan N et al. Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: a characterization study. Drug Des. Devel. Ther. 8, 1003-1012 (2014).
    • (2014) Drug Des. Devel. Ther. , vol.8 , pp. 1003-1012
    • Mooranian, A.1    Negrulj, R.2    Chen-Tan, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.