-
1
-
-
84874585944
-
-
Available at Accessed January 2011
-
IDF Diabetes Atlas. Available at http://www.diabetesatlas.org/. Accessed January 2011.
-
IDF Diabetes Atlas
-
-
-
2
-
-
58249110568
-
Role of bile acids and bile acid receptors in metabolic regulation
-
Lefebvre P, Cariou B, Lien F, et al. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev. 2009;89:147-91.
-
(2009)
Physiol Rev
, vol.89
, pp. 147-191
-
-
Lefebvre, P.1
Cariou, B.2
Lien, F.3
-
4
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
DOI 10.1146/annurev.biochem.72.121801.161712
-
Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72:137-74. (Pubitemid 36930444)
-
(2003)
Annual Review of Biochemistry
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
5
-
-
0017643827
-
Effects of diabetes mellitus on cholesterol metabolism in man
-
Bennion LJ, Grundy SM. Effects of diabetes mellitus on cholesterol metabolism in man. N Engl J Med. 1977;296:1365-71. (Pubitemid 8127337)
-
(1977)
New England Journal of Medicine
, vol.296
, Issue.24
, pp. 1365-1371
-
-
Bennion, L.J.1
Grundy, S.M.2
-
6
-
-
0019935179
-
Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus
-
Abrams JJ, Ginsberg H, Grundy SM. Metabolism of cholesterol and plasma triglycerides in nonketotic diabetes mellitus. Diabetes. 1982;31:903-10. (Pubitemid 12013795)
-
(1982)
Diabetes
, vol.31
, Issue.10
, pp. 903-910
-
-
Abrams, J.J.1
Ginsberg, H.2
Grundy, S.M.3
-
7
-
-
77957960122
-
Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism
-
Brufau G, Stellaard F, Prado K, et al. Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism. Hepatology. 2010;52:1455-64.
-
(2010)
Hepatology
, vol.52
, pp. 1455-1464
-
-
Brufau, G.1
Stellaard, F.2
Prado, K.3
-
8
-
-
77956455354
-
Plasma bile acids are not associated with energy metabolism in humans
-
Brufau G, Bahr MJ, Staels B, et al. Plasma bile acids are not associated with energy metabolism in humans. Nutr Metab. 2010;7:73.
-
(2010)
Nutr Metab
, vol.7
, pp. 73
-
-
Brufau, G.1
Bahr, M.J.2
Staels, B.3
-
9
-
-
78649735772
-
Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
-
Suhre K, Meisinger C, Döring A, et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS ONE. 2010;5:e13953.
-
(2010)
PLoS ONE
, vol.5
-
-
Suhre, K.1
Meisinger, C.2
Döring, A.3
-
10
-
-
0037072876
-
Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts
-
Hyogo H, Roy S, Paigen B, et al. Leptin promotes biliary cholesterol elimination during weight loss in ob/ob mice by regulating the enterohepatic circulation of bile salts. J Biol Chem. 2002;277:34117-24.
-
(2002)
J Biol Chem
, vol.277
, pp. 34117-34124
-
-
Hyogo, H.1
Roy, S.2
Paigen, B.3
-
11
-
-
77950602541
-
Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor-and liver X receptor alpha-controlled metabolic pathways in mice
-
This study is the first to give detailed insight into bile acid kinetics after sequestration in diabetic animal models
-
Herrema H, Meissner M, van Dijk TH et al. Bile salt sequestration induces hepatic de novo lipogenesis through farnesoid X receptor-and liver X receptor alpha-controlled metabolic pathways in mice. Hepatology. 2010; 51:806-816. This study is the first to give detailed insight into bile acid kinetics after sequestration in diabetic animal models.
-
(2010)
Hepatology
, vol.51
, pp. 806-816
-
-
Herrema, H.1
Meissner, M.2
Van Dijk, T.H.3
-
12
-
-
77957002345
-
Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities
-
This paper elegantly shows that short-circuiting of bile acid cycling might contribute to the metabolic improvements observed after bariatric surgery
-
Kohli R, Kirby M, Setchell KDR et al. Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol. 2010; 299:G652-60. This paper elegantly shows that short-circuiting of bile acid cycling might contribute to the metabolic improvements observed after bariatric surgery.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.299
-
-
Kohli, R.1
Kirby, M.2
Setchell, K.D.R.3
-
13
-
-
69749127975
-
Serum bile acids are higher in humans with prior gastric bypass: Potential contribution to improved glucose and lipid metabolism
-
Patti M, Houten SM, Bianco AC, et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity. 2009;17:1671-7.
-
(2009)
Obesity
, vol.17
, pp. 1671-1677
-
-
Patti, M.1
Houten, S.M.2
Bianco, A.C.3
-
14
-
-
77955667250
-
Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice
-
Li T, Owsley E, Matozel M, et al. Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice. Hepatology. 2010;52:678-90.
-
(2010)
Hepatology
, vol.52
, pp. 678-690
-
-
Li, T.1
Owsley, E.2
Matozel, M.3
-
15
-
-
78650213711
-
Bile acid sequestrants: Glucose-lowering mechanisms
-
Prawitt J, Staels B. Bile acid sequestrants: glucose-lowering mechanisms. Metab Syndr Relat Disord. 2010;8 Suppl 1:S3-8.
-
(2010)
Metab Syndr Relat Disord
, vol.8
, Issue.SUPPL. 1
-
-
Prawitt, J.1
Staels, B.2
-
16
-
-
77950620903
-
The effect of colesevelam hydrochloride on insulin sensitivity and secretion in patients with type 2 diabetes: A pilot study
-
Schwartz SL, Lai Y, Xu J, et al. The effect of colesevelam hydrochloride on insulin sensitivity and secretion in patients with type 2 diabetes: a pilot study. Metab Syndr Relat Disord. 2010;8:179-88.
-
(2010)
Metab Syndr Relat Disord
, vol.8
, pp. 179-188
-
-
Schwartz, S.L.1
Lai, Y.2
Xu, J.3
-
17
-
-
33847057732
-
Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin
-
Kobayashi M, Ikegami H, Fujisawa T, et al. Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin. Diabetes. 2007;56:239-47.
-
(2007)
Diabetes
, vol.56
, pp. 239-247
-
-
Kobayashi, M.1
Ikegami, H.2
Fujisawa, T.3
-
18
-
-
77249142314
-
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
-
Shang Q, Saumoy M, Holst JJ, et al. Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1. Am J Physiol Gastrointest Liver Physiol. 2010;298:G419-24.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.298
-
-
Shang, Q.1
Saumoy, M.2
Holst, J.J.3
-
19
-
-
77953766726
-
Cholestyramine reverses hyperglycemia and enhances GLP-1 release in Zucker Diabetic Fatty rats
-
Chen L, McNulty J, Anderson D, et al. Cholestyramine reverses hyperglycemia and enhances GLP-1 release in Zucker Diabetic Fatty rats. J Pharmacol Exp Ther. 2010;334:164-70.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 164-170
-
-
Chen, L.1
McNulty, J.2
Anderson, D.3
-
21
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki T, Choi M, Moschetta A, et al. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab. 2005;2:217-25.
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
-
22
-
-
0003269455
-
A G protein-coupled receptor responsive to bile acids
-
DOI 10.1074/jbc.M209706200
-
Kawamata Y, Fujii R, HosoyaM, et al. A G protein-coupled receptor responsive to bile acids. J Biol Chem. 2003;278:9435-40. (Pubitemid 36800434)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 9435-9440
-
-
Kawamata, Y.1
Fujii, R.2
Hosoya, M.3
Harada, M.4
Yoshida, H.5
Miwa, M.6
Fukusumi, S.7
Habata, Y.8
Itoh, T.9
Shintani, Y.10
Hinuma, S.11
Fujisawa, Y.12
Fujino, M.13
-
23
-
-
0036432845
-
Identification of membrane-type receptor for bile acids (M-BAR)
-
DOI 10.1016/S0006-291X(02)02550-0, PII S0006291X02025500
-
Maruyama T, Miyamoto Y, Nakamura T, et al. Identification of membrane-type receptor for bile acids (M-BAR). Biochem Biophys Res Commun. 2002;298:714-9. (Pubitemid 35356798)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.298
, Issue.5
, pp. 714-719
-
-
Maruyama, T.1
Miyamoto, Y.2
Nakamura, T.3
Tamai, Y.4
Okada, H.5
Sugiyama, E.6
Nakamura, T.7
Itadani, H.8
Tanaka, K.9
-
24
-
-
55049094158
-
Bile acids and signal transduction: Role in glucose homeostasis
-
Nguyen A, Bouscarel B. Bile acids and signal transduction: role in glucose homeostasis. Cell Signal. 2008;20:2180-97.
-
(2008)
Cell Signal
, vol.20
, pp. 2180-2197
-
-
Nguyen, A.1
Bouscarel, B.2
-
25
-
-
1842527650
-
Glucose Regulates the Expression of the Farnesoid X Receptor in Liver
-
DOI 10.2337/diabetes.53.4.890
-
Duran-Sandoval D, Mautino G, Martin G, et al. Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes. 2004;53:890-8. (Pubitemid 38436600)
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 890-898
-
-
Duran-Sandoval, D.1
Mautino, G.2
Martin, G.3
Percevault, F.4
Barbier, O.5
Fruchart, J.-C.6
Kuipers, F.7
Staels, B.8
-
26
-
-
22544452537
-
The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition
-
DOI 10.1074/jbc.M501931200
-
Duran-Sandoval D, Cariou B, Percevault F, et al. The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition. J Biol Chem. 2005;280:29971-9. (Pubitemid 41177076)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.33
, pp. 29971-29979
-
-
Duran-Sandoval, D.1
Cariou, B.2
Percevault, F.3
Hennuyer, N.4
Grefhorst, A.5
Van Dijk, T.H.6
Gonzalez, F.J.7
Fruchart, J.-C.8
Kuipers, F.9
Staels, B.10
-
27
-
-
2542435874
-
Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1
-
DOI 10.1074/jbc.M314322200
-
Yamagata K, Daitoku H, Shimamoto Y, et al. Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1. J Biol Chem. 2004;279:23158-65. (Pubitemid 38685621)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.22
, pp. 23158-23165
-
-
Yamagata, K.1
Daitoku, H.2
Shimamoto, Y.3
Matsuzaki, H.4
Hirota, K.5
Ishida, J.6
Fukamizu, A.7
-
28
-
-
33645509321
-
Farnesoid X receptor is essential for normal glucose homeostasis
-
Ma K, Saha PK, Chan L, et al. Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest. 2006;116:1102-9.
-
(2006)
J Clin Invest
, vol.116
, pp. 1102-1109
-
-
Ma, K.1
Saha, P.K.2
Chan, L.3
-
29
-
-
14244264780
-
Regulation of carbohydrate metabolism by the farnesoid X receptor
-
DOI 10.1210/en.2004-0965
-
Stayrook KR, Bramlett KS, Savkur RS, et al. Regulation of carbohydrate metabolism by the farnesoid X receptor. Endocrinology. 2005;146:984-91. (Pubitemid 40289284)
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 984-991
-
-
Stayrook, K.R.1
Bramlett, K.S.2
Savkur, R.S.3
Ficorilli, J.4
Cook, T.5
Christe, M.E.6
Michael, L.F.7
Burris, T.P.8
-
30
-
-
32244447570
-
Activation of the nuclear FXR improves hyperglycemia and hyperlipidemia in diabetic mice
-
DOI 10.1073/pnas.0506982103
-
Zhang Y, Lee FY, Barrera G, et al. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. Proc Natl Acad Sci USA. 2006;103:1006-11. (Pubitemid 43212212)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.4
, pp. 1006-1011
-
-
Zhang, Y.1
Lee, F.Y.2
Barrera, G.3
Lee, H.4
Vales, C.5
Gonzalez, F.J.6
Willson, T.M.7
Edwards, P.A.8
-
31
-
-
33645531297
-
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice
-
DOI 10.1074/jbc.M510258200
-
Cariou B, van Harmelen K, Duran-Sandoval D, et al. The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice. J Biol Chem. 2006;281:11039-49. (Pubitemid 43855527)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.16
, pp. 11039-11049
-
-
Cariou, B.1
Van Harmelen, K.2
Duran-Sandoval, D.3
Van Dijk, T.H.4
Grefhorst, A.5
Abdelkarim, M.6
Caron, S.7
Torpier, G.8
Fruchart, J.-C.9
Gonzalez, F.J.10
Kuipers, F.11
Staels, B.12
-
32
-
-
77950613528
-
FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats
-
Cipriani S, Mencarelli A, Palladino G, et al. FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats. J Lipid Res. 2010;51:771-84.
-
(2010)
J Lipid Res
, vol.51
, pp. 771-784
-
-
Cipriani, S.1
Mencarelli, A.2
Palladino, G.3
-
33
-
-
77953708142
-
The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity
-
Popescu IR, Helleboid-Chapman A, Lucas A, et al. The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity. FEBS Lett. 2010;584:2845-51.
-
(2010)
FEBS Lett
, vol.584
, pp. 2845-2851
-
-
Popescu, I.R.1
Helleboid-Chapman, A.2
Lucas, A.3
-
34
-
-
74849097076
-
The bile acid sensor FXR regulates insulin transcription and secretion
-
Renga B, Mencarelli A, Vavassori P, et al. The bile acid sensor FXR regulates insulin transcription and secretion. Biochim Biophys Acta. 2010;1802:363-72.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 363-372
-
-
Renga, B.1
Mencarelli, A.2
Vavassori, P.3
-
35
-
-
13844299425
-
Bile acids promote glucagon-like peptide-1 secretion through tgr5 in a murine enteroendocrine cell line stc-1
-
Katsuma SEA. Bile acids promote glucagon-like peptide-1 secretion through tgr5 in a murine enteroendocrine cell line stc-1. Biochem Biophys Res Commun. 2005;329:386-90.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 386-390
-
-
Katsuma, S.E.A.1
-
36
-
-
34548611093
-
Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea
-
DOI 10.1016/j.bbrc.2007.06.130, PII S0006291X07013538
-
Sato H, Genet C, Strehle A, et al. Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochem Biophys Res Commun. 2007;362:793-8. (Pubitemid 47398870)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.362
, Issue.4
, pp. 793-798
-
-
Sato, H.1
Genet, C.2
Strehle, A.3
Thomas, C.4
Lobstein, A.5
Wagner, A.6
Mioskowski, C.7
Auwerx, J.8
Saladin, R.9
-
37
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
This elaborate study is the first to propose a mechanism by which bile acids might improve glucose homeostasis via TGR5
-
Thomas C, Gioiello A, Noriega L et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009; 10:167-177. This elaborate study is the first to propose a mechanism by which bile acids might improve glucose homeostasis via TGR5.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
-
38
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
DOI 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006;313:1137-40. (Pubitemid 44300242)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
39
-
-
77955411159
-
Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
-
This is one of the rare investigations of receptor-independent effects of bile acids on insulin sensitivity in human patients
-
Kars M, Yang L, Gregor MF et al. Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes. 2010; 59:1899-1905. This is one of the rare investigations of receptor-independent effects of bile acids on insulin sensitivity in human patients.
-
(2010)
Diabetes
, vol.59
, pp. 1899-1905
-
-
Kars, M.1
Yang, L.2
Gregor, M.F.3
-
40
-
-
33748940093
-
The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo
-
DOI 10.1124/mol.106.023820
-
Rizzo G, Disante M, Mencarelli A, et al. The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo. Mol Pharmacol. 2006;70:1164-73. (Pubitemid 44435967)
-
(2006)
Molecular Pharmacology
, vol.70
, Issue.4
, pp. 1164-1173
-
-
Rizzo, G.1
Disante, M.2
Mencarelli, A.3
Renga, B.4
Gioiello, A.5
Pellicciari, R.6
Fiorucci, S.7
-
41
-
-
78449258535
-
The Farnesoid X Receptor Regulates Adipocyte Differentiation and Function by Promoting Peroxisome Proliferator-activated Receptor-{gamma} and Interfering with the Wnt/{beta}-Catenin Pathways
-
Abdelkarim M, Caron S, Duhem C, et al. The Farnesoid X Receptor Regulates Adipocyte Differentiation and Function by Promoting Peroxisome Proliferator-activated Receptor-{gamma} and Interfering with the Wnt/{beta}-Catenin Pathways. J Biol Chem. 2010;285:36759-67.
-
(2010)
J Biol Chem
, vol.285
, pp. 36759-36767
-
-
Abdelkarim, M.1
Caron, S.2
Duhem, C.3
-
42
-
-
2542505481
-
Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
-
DOI 10.1210/en.2003-1671
-
Fu L, John LM, Adams SH, et al. Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes. Endocrinology. 2004;145:2594-603. (Pubitemid 38686202)
-
(2004)
Endocrinology
, vol.145
, Issue.6
, pp. 2594-2603
-
-
Fu, L.1
John, L.M.2
Adams, S.H.3
Yu, X.X.4
Tomlinson, E.5
Renz, M.6
Williams, P.M.7
Soriano, R.8
Corpuz, R.9
Moffat, B.10
Vandlen, R.11
Simmons, L.12
Foster, J.13
Stephan, J.-P.14
Tsai, S.P.15
Stewart, T.A.16
-
43
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
DOI 10.1038/nature04330, PII NATURE04330
-
Watanabe M, Houten SM, Mataki C, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006;439:484-9. (Pubitemid 43152840)
-
(2006)
Nature
, vol.439
, Issue.7075
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Bianco, A.C.12
Auwerx, J.13
-
44
-
-
33751066787
-
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
-
DOI 10.1677/joe.1.06546
-
Maruyama T, Tanaka K, Suzuki J, et al. Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice. J Endocrinol. 2006;191:197-205. (Pubitemid 44756522)
-
(2006)
Journal of Endocrinology
, vol.191
, Issue.1
, pp. 197-205
-
-
Maruyama, T.1
Tanaka, K.2
Suzuki, J.3
Miyoshi, H.4
Harada, N.5
Nakamura, T.6
Miyamoto, Y.7
Kanatani, A.8
Tamai, Y.9
-
45
-
-
77956431307
-
Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance
-
López M, Varela L, Vázquez MJ, et al. Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med. 2010;16:1001-8.
-
(2010)
Nat Med
, vol.16
, pp. 1001-1008
-
-
López, M.1
Varela, L.2
Vázquez, M.J.3
-
46
-
-
0037462815
-
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis
-
DOI 10.1074/jbc.M209525200
-
Lambert G, Amar MJA, Guo G, et al. The farnesoid X-receptor is an essential regulator of cholesterol homeostasis. J Biol Chem. 2003;278:2563-70. (Pubitemid 36801334)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.4
, pp. 2563-2570
-
-
Lambert, G.1
Amar, M.J.A.2
Guo, G.3
Brewer Jr., H.B.4
Gonzalez, F.J.5
Sinal, C.J.6
-
47
-
-
0017836529
-
Chenodeoxycholic acid therapy for hypertriglyceridaemia in men
-
Bateson MC, Maclean D, Evans JR, et al. Chenodeoxycholic acid therapy for hypertriglyceridaemia in men. Br J Clin Pharmacol. 1978;5:249-54. (Pubitemid 8279921)
-
(1978)
British Journal of Clinical Pharmacology
, vol.5
, Issue.3
, pp. 249-254
-
-
Bateson, M.C.1
Maclean, D.2
Evans, J.R.3
Bouchier, I.A.D.4
-
48
-
-
85047694456
-
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c
-
DOI 10.1172/JCI200421025
-
Watanabe M, Houten SM, Wang L, et al. Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c. J Clin Invest. 2004;113:1408-18. (Pubitemid 39071696)
-
(2004)
Journal of Clinical Investigation
, vol.113
, Issue.10
, pp. 1408-1418
-
-
Watanabe, M.1
Houten, S.M.2
Wang, L.3
Moschetta, A.4
Mangelsdorf, D.J.5
Heyman, R.A.6
Moore, D.D.7
Auwerx, J.8
-
50
-
-
78650069937
-
Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice
-
Volynets V, Spruss A, Kanuri G, et al. Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice. J Lipid Res. 2010;51:3414-24.
-
(2010)
J Lipid Res
, vol.51
, pp. 3414-3424
-
-
Volynets, V.1
Spruss, A.2
Kanuri, G.3
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