Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in Mice

Hypertension

Volumn 69, Issue 6, 2017, Pages 1198-1206

  Gao, Lie ^a   Zimmerman, Matthew C ^a   Biswal, Shyam ^b   Zucker, Irving H ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

arterial baroreflex; blood pressure; brain stem; oxidative stress; sympathetic regulation

Indexed keywords

CATALASE; CRE RECOMBINASE; GREEN FLUORESCENT PROTEIN; HEME OXYGENASE 1; LENTIVIRUS VECTOR; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; NORADRENALIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; NFE2L2 PROTEIN, MOUSE;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BRAIN STEM; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; HOMEOSTASIS; HYPERTENSION; IMMUNOFLUORESCENCE; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NERVE CONDUCTION; NONHUMAN; NORADRENALIN URINE LEVEL; NRF2 GENE; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL SYMPATHETIC NERVE ACTIVITY; ROSTRAL VENTROLATERAL MEDULLA; SYMPATHETIC TONE; ADRENERGIC SYSTEM; ANIMAL; DISEASE MODEL; GENETICS; HEART RATE; MEDULLA OBLONGATA; METABOLISM; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; RANDOMIZATION; REAL TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT;

ANIMALS; ANTIOXIDANTS; BAROREFLEX; BLOOD PRESSURE DETERMINATION; DISEASE MODELS, ANIMAL; FEMALE; GENE DELETION; HEART RATE; HOMEOSTASIS; HYPERTENSION; MALE; MEDULLA OBLONGATA; MICE; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; RANDOM ALLOCATION; REAL-TIME POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RNA, MESSENGER; SYMPATHETIC NERVOUS SYSTEM;

EID: 85019884852     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.117.09123     Document Type: Article

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