NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla

Circulation Research

Volumn 97, Issue 8, 2005, Pages 772-780

  Chan, Samuel H H ^a   Hsu, Kuei Sen ^b   Huang, Chiung Chun ^b   Wang, Ling Lin ^c   Ou, Chen Chun ^c   Chan, Julie Y H ^c  

^a NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Angiotensin II; Blood pressure; Mitogen activated protein kinases; NADPH oxidase; Rostral ventrolateral medulla; Superoxide anion

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTISENSE OLIGONUCLEOTIDE; DIPHENYLIODONIUM SALT; GLUTAMIC ACID; ISOENZYME; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGEN; PROTEIN P22PHOX; PROTEIN P47PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; SUPEROXIDE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME PHOSPHORYLATION; MALE; MEDULLA OBLONGATA; MICROINJECTION; NONHUMAN; PREMOTOR CORTEX; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; ROSTRAL VENTROLATERAL MEDULLA; SIGNAL TRANSDUCTION; SYMPATHETIC NERVE;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; IMIDAZOLES; LOSARTAN; MALE; MEDULLA OBLONGATA; NADPH OXIDASE; OLIGONUCLEOTIDES, ANTISENSE; ONIUM COMPOUNDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; SIGNAL TRANSDUCTION; SUPEROXIDES; SYMPATHETIC NERVOUS SYSTEM;

EID: 26844522807     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000185804.79157.C0     Document Type: Article

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