SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity

European Heart Journal

Volumn 38, Issue 18, 2017, Pages 1389-1398

  Luo, Yu Xuan ^a   Tang, Xiaoqiang ^a   An, Xi Zhou ^a   Xie, Xue Min ^a   Chen, Xiao Feng ^a   Zhao, Xiang ^a   Hao, De Long ^a   Chen, Hou Zao ^a   Liu, De Pei ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Cardiac hypertrophy; MnSOD; Oxidative stress; Sirt4

Indexed keywords

ANGIOTENSIN II; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SIRTUIN 3; SIRTUIN 4; MITOCHONDRIAL PROTEIN; SIRT4 PROTEIN, MOUSE; SIRTUIN; SUPEROXIDE DISMUTASE; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; ENZYME INHIBITION; GENE OVEREXPRESSION; HEART DISEASE; HEART FUNCTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ACETYLATION; TRANSGENIC MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CARDIOMEGALY; ENZYMOLOGY; GENE KNOCKDOWN; HEART MITOCHONDRION; PHYSIOLOGY; VASCULAR REMODELING;

ANGIOTENSIN II; ANIMALS; CARDIOMEGALY; GENE KNOCKDOWN TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; MYOCYTES, CARDIAC; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIRTUINS; SUPEROXIDE DISMUTASE; VASCULAR REMODELING; VASOCONSTRICTOR AGENTS;

EID: 85019716725     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehw138     Document Type: Article

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