Interferon-γ limits diabetogenic CD8+ T-cell effector responses in type 1 diabetes

Diabetes

Volumn 66, Issue 3, 2017, Pages 710-721

  Driver, John P ^a   Racine, Jeremy J ^b   Ye, Cheng ^a   Lamont, Deanna J ^b   Newby, Brittney N ^c   Leeth, Caroline M ^b   Chapman, Harold D ^b   Brusko, Todd M ^c   Chen, Yi Guang ^d   Mathews, Clayton E ^c   Serreze, David V ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b JACKSON LABORATORY   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^d MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; HLA A2 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 2 RECEPTOR ALPHA; MELAN A; MESSENGER RNA; RAG1 PROTEIN; STAT1 PROTEIN; STAT4 PROTEIN; TRANSCRIPTION FACTOR FOXP3; LYMPHOCYTE ANTIGEN RECEPTOR; STAT1 PROTEIN, MOUSE; STAT4 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DIABETOGENESIS; EFFECTOR CELL; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; UPREGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; NONOBESE DIABETIC MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN; STAT1 TRANSCRIPTION FACTOR; STAT4 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 85019616155     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db16-0846     Document Type: Article

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