메뉴 건너뛰기




Volumn 18, Issue 4, 2017, Pages 905-915

Enterolactone suppresses proliferation, migration and metastasis of MDA-MB-231 breast cancer cells through inhibition of uPA induced plasmin activation and MMPs-Mediated ECM remodeling

Author keywords

Breast cancer; Enterolactone; Matrix metalloproteinases; Urokinase type plasminogen activator

Indexed keywords


EID: 85019614557     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.22034/APJCP.2017.18.4.905     Document Type: Article
Times cited : (45)

References (55)
  • 1
    • 85015097431 scopus 로고    scopus 로고
    • A review on the anti-carcinogenic and anti-metastatic effects of flax seed lignan secolariciresinol diglucoside (SDG)
    • Alphonse P, Aluko R (2015). A review on the anti-carcinogenic and anti-metastatic effects of flax seed lignan secolariciresinol diglucoside (SDG). Discov Phytomedicine, 2, 12-7.
    • (2015) Discov Phytomedicine , vol.2 , pp. 12-17
    • Alphonse, P.1    Aluko, R.2
  • 2
    • 0033981473 scopus 로고    scopus 로고
    • The plasminogen activation system in tumor growth, invasion, and metastasis
    • Andreasen PA, Egelund R, Petersen HH (2000). The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci, 57, 25-40.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 25-40
    • Andreasen, P.A.1    Egelund, R.2    Petersen, H.H.3
  • 4
  • 5
    • 80051691520 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator and the generation of inhibitors of urokinase activity and signaling
    • Carriero MV, Stoppelli MP (2011). The urokinase-type plasminogen activator and the generation of inhibitors of urokinase activity and signaling. Curr Pharm De, 17, 1944-61.
    • (2011) Curr Pharm De , vol.17 , pp. 1944-1961
    • Carriero, M.V.1    Stoppelli, M.P.2
  • 6
    • 84983249246 scopus 로고    scopus 로고
    • Pleiotropic roles of metalloproteinases in hematological malignancies: an update
    • Chaudhary AK, Chaudhary S, Ghosh K, et al (2016). Pleiotropic roles of metalloproteinases in hematological malignancies: an update. Asian Pacific J Cancer Prev, 17, 3043-51.
    • (2016) Asian Pacific J Cancer Prev , vol.17 , pp. 3043-3051
    • Chaudhary, A.K.1    Chaudhary, S.2    Ghosh, K.3
  • 7
    • 34548443813 scopus 로고    scopus 로고
    • Flaxseed alone or in combination with tamoxifen inhibits MCF-7 breast tumor growth in ovariectomized athymic mice with high circulating levels of estrogen
    • Chen J, Power KA, Mann J, et al (2007). Flaxseed alone or in combination with tamoxifen inhibits MCF-7 breast tumor growth in ovariectomized athymic mice with high circulating levels of estrogen. Exp Biol Med, 232, 1071-80.
    • (2007) Exp Biol Med , vol.232 , pp. 1071-1080
    • Chen, J.1    Power, K.A.2    Mann, J.3
  • 8
    • 0036966926 scopus 로고    scopus 로고
    • Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor
    • Chen J, Stavro PM, Thompson LU (2002). Dietary flaxseed inhibits human breast cancer growth and metastasis and downregulates expression of insulin-like growth factor and epidermal growth factor receptor. Nutr Cancer, 43, 187-92.
    • (2002) Nutr Cancer , vol.43 , pp. 187-192
    • Chen, J.1    Stavro, P.M.2    Thompson, L.U.3
  • 9
    • 0038336609 scopus 로고    scopus 로고
    • Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro
    • Chen J, Thompson LU (2003). Lignans and tamoxifen, alone or in combination, reduce human breast cancer cell adhesion, invasion and migration in vitro. Breast Cancer Res Treat, 80, 163-70.
    • (2003) Breast Cancer Res Treat , vol.80 , pp. 163-170
    • Chen, J.1    Thompson, L.U.2
  • 10
    • 33645009635 scopus 로고    scopus 로고
    • Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice
    • Chen J, Wang L, Thompson LU (2006). Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice. Cancer Lett, 234, 168-75.
    • (2006) Cancer Lett , vol.234 , pp. 168-175
    • Chen, J.1    Wang, L.2    Thompson, L.U.3
  • 11
    • 79952340427 scopus 로고    scopus 로고
    • Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
    • Cox TR, Erler JT (2011). Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Dis Model Mech, 4, 165-78.
    • (2011) Dis Model Mech , vol.4 , pp. 165-178
    • Cox, T.R.1    Erler, J.T.2
  • 12
    • 0037044563 scopus 로고    scopus 로고
    • Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts
    • Dabrosin C, Chen J, Wang L, et al (2002). Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts. Cancer Lett, 185, 31-37.
    • (2002) Cancer Lett , vol.185 , pp. 31-37
    • Dabrosin, C.1    Chen, J.2    Wang, L.3
  • 13
    • 40549131272 scopus 로고    scopus 로고
    • Extracellular matrix dynamics in development and regenerative medicine
    • Daley WP, Peters SB, Larsen M (2008). Extracellular matrix dynamics in development and regenerative medicine. J Cell Sci, 121, 255-64.
    • (2008) J Cell Sci , vol.121 , pp. 255-264
    • Daley, W.P.1    Peters, S.B.2    Larsen, M.3
  • 14
    • 85019623074 scopus 로고    scopus 로고
    • Cell surface remodeling by plasmin: A new function for an old enzyme
    • Deryugina EI, Quigley JP (2012). Cell surface remodeling by plasmin: A new function for an old enzyme. J Biomed Biotechnol, 56, 4259-80.
    • (2012) J Biomed Biotechnol , vol.56 , pp. 4259-4280
    • Deryugina, E.I.1    Quigley, J.P.2
  • 15
    • 33646576169 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tumor metastasis
    • Deryugina EI, Quigley JP (2006). Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev, 25, 9-34.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 9-34
    • Deryugina, E.I.1    Quigley, J.P.2
  • 16
    • 84929020541 scopus 로고    scopus 로고
    • From plasminogen to plasmin: role of plasminogen receptors in human cancer
    • Didiasova M, Wujak L, Wygrecka M, et al (2014). From plasminogen to plasmin: role of plasminogen receptors in human cancer. Int J Mol Sci, 15, 21229-52.
    • (2014) Int J Mol Sci , vol.15 , pp. 21229-21252
    • Didiasova, M.1    Wujak, L.2    Wygrecka, M.3
  • 17
    • 0347917028 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system: role in malignancy
    • Duffy MJ (2004). The urokinase plasminogen activator system: role in malignancy. Curr Pharm Des, 10, 39-49.
    • (2004) Curr Pharm Des , vol.10 , pp. 39-49
    • Duffy, M.J.1
  • 18
    • 84910070390 scopus 로고    scopus 로고
    • uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies
    • Duffy MJ, McGowan PM, Harbeck N, et al (2014). uPA and PAI-1 as biomarkers in breast cancer: validated for clinical use in level-of-evidence-1 studies. Breast Cancer Res, 16, 428.
    • (2014) Breast Cancer Res , vol.16 , pp. 428
    • Duffy, M.J.1    McGowan, P.M.2    Harbeck, N.3
  • 19
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z (2002). New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer, 2, 161-74.
    • (2002) Nat Rev Cancer , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 20
    • 55749115443 scopus 로고    scopus 로고
    • Growth inhibition of human MDA-MB-231 breast cancer cells by?. tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product
    • Elangovan S, Hsieh TC, Wu JM (2008). Growth inhibition of human MDA-MB-231 breast cancer cells by?-tocotrienol is associated with loss of cyclin D1/CDK4 expression and accompanying changes in the state of phosphorylation of the retinoblastoma tumor suppressor gene product. Anticancer Res, 28, 2641-47.
    • (2008) Anticancer Res , vol.28 , pp. 2641-2647
    • Elangovan, S.1    Hsieh, T.C.2    Wu, J.M.3
  • 21
    • 84900801175 scopus 로고    scopus 로고
    • Flax and breast cancer: A systematic review
    • Flower G, Fritz H, Balneaves LG, et al (2014). Flax and breast cancer: A systematic review. Integr Cancer Ther, 13, 181-92.
    • (2014) Integr Cancer Ther , vol.13 , pp. 181-192
    • Flower, G.1    Fritz, H.2    Balneaves, L.G.3
  • 22
    • 84855959252 scopus 로고    scopus 로고
    • Use of gel zymography to examine matrix metalloproteinase (Gelatinase) expression in brain tissue or in primary Glial cultures
    • Frankowski H, Gu YH, Heo JH (2012). Use of gel zymography to examine matrix metalloproteinase (Gelatinase) expression in brain tissue or in primary Glial cultures. Methods Mol Biol, 814, 221-33.
    • (2012) Methods Mol Biol , vol.814 , pp. 221-233
    • Frankowski, H.1    Gu, Y.H.2    Heo, J.H.3
  • 23
    • 84901847884 scopus 로고    scopus 로고
    • Bioaccessibility of lignans from flaxseed (Linum usitatissimum L. ) determined by single-batch in vitro simulation of the digestive process
    • Fuentealba C, Figuerola F, Estévez AM, et al (2014). Bioaccessibility of lignans from flaxseed (Linum usitatissimum L. ) determined by single-batch in vitro simulation of the digestive process. J Sci Food Agric, 94, 1729-38.
    • (2014) J Sci Food Agric , vol.94 , pp. 1729-1738
    • Fuentealba, C.1    Figuerola, F.2    Estévez, A.M.3
  • 24
    • 67650504966 scopus 로고    scopus 로고
    • TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays
    • Gebäck T, Schulz MMP, Koumoutsakos P (2009). TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques, 46, 265-74.
    • (2009) Biotechniques , vol.46 , pp. 265-274
    • Gebäck, T.1    Schulz, M.M.P.2    Koumoutsakos, P.3
  • 25
    • 26244464309 scopus 로고    scopus 로고
    • ECM degrading proteases and tissue remodelling in the mammary gland
    • Green KA, Lund LR (2005). ECM degrading proteases and tissue remodelling in the mammary gland. Bioessays, 27, 894-03.
    • (2005) Bioessays , vol.27 , pp. 803-894
    • Green, K.A.1    Lund, L.R.2
  • 26
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: not just pretty fibrils
    • Hynes RO (2009). The extracellular matrix: not just pretty fibrils. Science, 326, 1216-9.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 27
    • 33847392879 scopus 로고    scopus 로고
    • Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
    • Jungeström MB, Thompson LU, Dabrosin C (2007). Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo. Clin Cancer Res, 13, 1061-67.
    • (2007) Clin Cancer Res , vol.13 , pp. 1061-1067
    • Jungeström, M.B.1    Thompson, L.U.2    Dabrosin, C.3
  • 29
    • 34548403115 scopus 로고    scopus 로고
    • Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis
    • Kass L, Erler JT, Dembo M (2007). Mammary epithelial cell: Influence of extracellular matrix composition and organization during development and tumorigenesis. Int J Biochem Cell Biol, 39, 1987-94.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1987-1994
    • Kass, L.1    Erler, J.T.2    Dembo, M.3
  • 30
    • 77950931419 scopus 로고    scopus 로고
    • Matrix metalloproteinases: regulators of the tumor microenvironment
    • Kessenbrock K, Plaks V, Werb Z (2010). Matrix metalloproteinases: regulators of the tumor microenvironment. Cell, 141, 52-67.
    • (2010) Cell , vol.141 , pp. 52-67
    • Kessenbrock, K.1    Plaks, V.2    Werb, Z.3
  • 31
    • 14944361909 scopus 로고    scopus 로고
    • Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential
    • Kousidou OC, Roussidis AE, Theocharis AD (2004). Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential. Anticancer Res, 24, 4025-30.
    • (2004) Anticancer Res , vol.24 , pp. 4025-4030
    • Kousidou, O.C.1    Roussidis, A.E.2    Theocharis, A.D.3
  • 32
    • 70450222098 scopus 로고    scopus 로고
    • Matrix crosslinking forces tumor progression by enhancing integrin signaling
    • Levental KR, Yu H, Kass L, et al (2009). Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell, 139, 891-06.
    • (2009) Cell , vol.139 , pp. 891-906
    • Levental, K.R.1    Yu, H.2    Kass, L.3
  • 33
    • 84555179609 scopus 로고    scopus 로고
    • Extracellular matrix degradation and remodeling in development and disease
    • Lu P, Takai K, Weaver VM, Werb Z (2011). Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harb Perspect Biol, 3, 1-24.
    • (2011) Cold Spring Harb Perspect Biol , vol.3 , pp. 1-24
    • Lu, P.1    Takai, K.2    Weaver, V.M.3    Werb, Z.4
  • 34
    • 84859949610 scopus 로고    scopus 로고
    • The extracellular matrix: A dynamic niche in cancer progression
    • Lu P, Weaver VM, Werb Z (2012). The extracellular matrix: A dynamic niche in cancer progression. J Cell Biol, 196, 395-06.
    • (2012) J Cell Biol , vol.196 , pp. 395-406
    • Lu, P.1    Weaver, V.M.2    Werb, Z.3
  • 35
    • 16544382310 scopus 로고    scopus 로고
    • Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro
    • Magee PJ, McGlynn H, Rowland IR (2004). Differential effects of isoflavones and lignans on invasiveness of MDA-MB-231 breast cancer cells in vitro. Cancer Lett, 208, 35-41.
    • (2004) Cancer Lett , vol.208 , pp. 35-41
    • Magee, P.J.1    McGlynn, H.2    Rowland, I.R.3
  • 36
    • 84865247185 scopus 로고    scopus 로고
    • In vitro anti-metastatic activity of enterolactone, a mammalian lignan derived from flax lignan, and down-regulation of matrix metalloproteinases in MCF-7 and MDA MB 231 cell lines
    • Mali AV, Wagh UV, Hegde MV (2012). In vitro anti-metastatic activity of enterolactone, a mammalian lignan derived from flax lignan, and down-regulation of matrix metalloproteinases in MCF-7 and MDA MB 231 cell lines. Indian J Cancer, 49, 181-7.
    • (2012) Indian J Cancer , vol.49 , pp. 181-187
    • Mali, A.V.1    Wagh, U.V.2    Hegde, M.V.3
  • 37
    • 84911134369 scopus 로고    scopus 로고
    • Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer
    • Mellatyar H, Akbarzadeh A, Rahmati M, et al (2014). Comparison of inhibitory effect of 17-DMAG nanoparticles and free 17-DMAG in HSP90 gene expression in lung cancer. Asian Pacific J Cancer Prev, 15, 8693-98.
    • (2014) Asian Pacific J Cancer Prev , vol.15 , pp. 8693-8698
    • Mellatyar, H.1    Akbarzadeh, A.2    Rahmati, M.3
  • 38
    • 56749133149 scopus 로고    scopus 로고
    • The ADAMs: signalling scissors in the tumour microenvironment
    • Murphy G (2008). The ADAMs: signalling scissors in the tumour microenvironment. Nat Rev Cancer, 8, 929-41.
    • (2008) Nat Rev Cancer , vol.8 , pp. 929-941
    • Murphy, G.1
  • 39
    • 0035990901 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion: Role for cell migration
    • Nabeshima K, Inoue T, Shimao Y, et al (2002). Matrix metalloproteinases in tumor invasion: Role for cell migration. Pathol Int, 52, 255-64.
    • (2002) Pathol Int , vol.52 , pp. 255-264
    • Nabeshima, K.1    Inoue, T.2    Shimao, Y.3
  • 40
    • 0042895837 scopus 로고    scopus 로고
    • Plasminogen binding and cancer: promises and pitfalls
    • Ranson M (2003). Plasminogen binding and cancer: promises and pitfalls. Front Biosci, 8, 294-04.
    • (2003) Front Biosci , vol.8 , pp. 294-304
    • Ranson, M.1
  • 41
    • 33745911131 scopus 로고    scopus 로고
    • Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts
    • Saarinen NM, Power K, Chen J, et al (2006). Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF-7 human breast cancer xenografts. Int J Cancer, 119, 925-31.
    • (2006) Int J Cancer , vol.119 , pp. 925-931
    • Saarinen, N.M.1    Power, K.2    Chen, J.3
  • 42
    • 79960209125 scopus 로고    scopus 로고
    • Cancer therapy trials employing level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1
    • Schmitt M, Harbeck N, Brünner N, et al (2011). Cancer therapy trials employing level-of-evidence-1 disease forecast cancer biomarkers uPA and its inhibitor PAI-1. Expert Rev Mol Diagn, 11, 617-34.
    • (2011) Expert Rev Mol Diagn , vol.11 , pp. 617-634
    • Schmitt, M.1    Harbeck, N.2    Brünner, N.3
  • 43
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative CT method
    • Schmittgen TD, Livak KJ (2008). Analyzing real-time PCR data by the comparative CT method. Nat Protoc, 3, 1101-08.
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 44
    • 78651388566 scopus 로고    scopus 로고
    • Plasminogen activator uPA is a direct transcriptional target of the JAG1-notch receptor signaling pathway in breast cancer
    • Shimizu M, Cohen B, Goldvasser P, et al (2011). Plasminogen activator uPA is a direct transcriptional target of the JAG1-notch receptor signaling pathway in breast cancer. Cancer Res, 71, 277-86.
    • (2011) Cancer Res , vol.71 , pp. 277-286
    • Shimizu, M.1    Cohen, B.2    Goldvasser, P.3
  • 45
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht MD, Werb Z (2001). How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol, 17, 463-16.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 46
    • 51149102710 scopus 로고    scopus 로고
    • Trypan blue exclusion test of cell viability
    • Strober W (2001). Trypan blue exclusion test of cell viability. Curr Protoc Immunol. A3-B. (vol)(pages?).
    • (2001) Curr Protoc Immunol , vol.A3-B
    • Strober, W.1
  • 47
    • 84865511829 scopus 로고    scopus 로고
    • Plasmin as a proinflammatory cell activator
    • Syrovets T, Lunov O, Simmet T (2012). Plasmin as a proinflammatory cell activator. J Leukoc Biol, 92, 509-19.
    • (2012) J Leukoc Biol , vol.92 , pp. 509-519
    • Syrovets, T.1    Lunov, O.2    Simmet, T.3
  • 48
    • 84875373539 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system in breast cancer invasion and metastasis
    • Tang L, Han X (2013). The urokinase plasminogen activator system in breast cancer invasion and metastasis. Biomed Pharmacother, 67, 179-82.
    • (2013) Biomed Pharmacother , vol.67 , pp. 179-182
    • Tang, L.1    Han, X.2
  • 49
    • 35548933803 scopus 로고    scopus 로고
    • Extracellular matrix: from atomic resolution to ultrastructure
    • Vakonakis I, Campbell ID (2007). Extracellular matrix: from atomic resolution to ultrastructure. Curr Opin Cell Biol, 19, 578-83.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 578-583
    • Vakonakis, I.1    Campbell, I.D.2
  • 50
    • 23244462764 scopus 로고    scopus 로고
    • The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components
    • Wang L, Chen J, Thompson LU (2005). The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Int J Cancer, 116, 793-8.
    • (2005) Int J Cancer , vol.116 , pp. 793-798
    • Wang, L.1    Chen, J.2    Thompson, L.U.3
  • 51
    • 0037174158 scopus 로고    scopus 로고
    • Mammalian phytoestrogens: Enterodiol and enterolactone
    • Wang LQ (2002). Mammalian phytoestrogens: Enterodiol and enterolactone. J Chromatogr B, 777, 289-09.
    • (2002) J Chromatogr B , vol.777 , pp. 289-309
    • Wang, L.Q.1
  • 52
    • 0023551893 scopus 로고
    • Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol
    • Welshons WV, Murphy CS, Koch R, et al (1987). Stimulation of breast cancer cells in vitro by the environmental estrogen enterolactone and the phytoestrogen equol. Breast Cancer Res Treat, 10, 169-75.
    • (1987) Breast Cancer Res Treat , vol.10 , pp. 169-175
    • Welshons, W.V.1    Murphy, C.S.2    Koch, R.3
  • 53
    • 84948715919 scopus 로고    scopus 로고
    • Inhibitory effects of enterolactone on growth and metastasis in human breast cancer
    • Xiong XY, Hu XJ, Li Y, et al (2015). Inhibitory effects of enterolactone on growth and metastasis in human breast cancer. Nutr Cancer, 67, 1326-34.
    • (2015) Nutr Cancer , vol.67 , pp. 1326-1334
    • Xiong, X.Y.1    Hu, X.J.2    Li, Y.3
  • 54
    • 0032570762 scopus 로고    scopus 로고
    • Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice
    • Yan L, Yee JA, Li D, et al (1998). Dietary flaxseed supplementation and experimental metastasis of melanoma cells in mice. Cancer Lett, 124, 181-6.
    • (1998) Cancer Lett , vol.124 , pp. 181-186
    • Yan, L.1    Yee, J.A.2    Li, D.3
  • 55
    • 78650552589 scopus 로고    scopus 로고
    • Forcing form and function: Biomechanical regulation of tumor evolution
    • Yu H, Mouw JK, Weaver VM (2011). Forcing form and function: Biomechanical regulation of tumor evolution. Trends Cell Biol, 21, 47-56.
    • (2011) Trends Cell Biol , vol.21 , pp. 47-56
    • Yu, H.1    Mouw, J.K.2    Weaver, V.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.