Histone deacetylase 10 structure and molecular function as a polyamine deacetylase

Nature Communications

Volumn 8, Issue , 2017, Pages

  Hai, Yang ^a,b   Shinsky, Stephen A ^a   Porter, Nicholas J ^a   Christianson, David W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b University of California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; HISTONE DEACETYLASE 10; HYDROGEN; RECOMBINANT ENZYME; SPERMIDINE; HDAC10 PROTEIN, HUMAN; HISTONE DEACETYLASE; ISOENZYME; PROTEIN BINDING; RECOMBINANT PROTEIN; SPERMINE; ZEBRAFISH PROTEIN;

CANCER; CRYSTAL STRUCTURE; CYPRINID; ENZYME; HYDROLYSIS; INHIBITOR; METABOLISM; MOLECULAR ANALYSIS;

AMINO ACID SEQUENCE; ARTICLE; AUTOPHAGY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CATALYTIC EFFICIENCY; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HUMAN; HYDROGEN BOND; HYDROLYSIS; KINETIC PARAMETERS; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NONHUMAN; POINT MUTATION; PROTEIN DEGRADATION; REGIOSELECTIVITY; STATIC ELECTRICITY; ALPHA HELIX; ANIMAL; BETA SHEET; CHEMISTRY; ENZYME ACTIVE SITE; GENE EXPRESSION; GENETICS; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR MODEL; PROTEIN DOMAIN; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY; ZEBRA FISH;

DANIO RERIO; HOMO SAPIENS; PYRONIA TITHONUS;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION; HISTONE DEACETYLASES; HUMANS; ISOENZYMES; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPERMIDINE; SPERMINE; SUBSTRATE SPECIFICITY; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 85019608402     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15368     Document Type: Article

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