-
1
-
-
13544253065
-
Metabolic syndrome: A clinical and molecular perspective
-
Moller DE, Kaufman KD. Metabolic syndrome: A clinical and molecular perspective. Ann Rev Med 2005;56:45-62
-
(2005)
Ann Rev Med
, vol.56
, pp. 45-62
-
-
Moller, D.E.1
Kaufman, K.D.2
-
3
-
-
84901424065
-
Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity
-
Huh JY, Park YJ, Ham M, Kim JB. Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity. Mol Cells 2014;37:365-371
-
(2014)
Mol Cells
, vol.37
, pp. 365-371
-
-
Huh, J.Y.1
Park, Y.J.2
Ham, M.3
Kim, J.B.4
-
5
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol 2011;11:738-749
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.3
-
6
-
-
79953815551
-
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
-
Wu D, Molofsky AB, Liang HE, et al. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science 2011;332:243-247
-
(2011)
Science
, vol.332
, pp. 243-247
-
-
Wu, D.1
Molofsky, A.B.2
Liang, H.E.3
-
7
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796-1808
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante, A.W.6
-
8
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009;15:914-920
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
-
9
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-184
-
(2007)
J Clin Invest
, vol.117
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
10
-
-
68349160704
-
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
-
Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009;15:940-945
-
(2009)
Nat Med
, vol.15
, pp. 940-945
-
-
Liu, J.1
Divoux, A.2
Sun, J.3
-
11
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009;15:930-939
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
-
12
-
-
53149119231
-
Neutrophils transiently infiltrate intra-Abdominal fat early in the course of high-fat feeding
-
Elgazar-Carmon V, Rudich A, Hadad N, Levy R. Neutrophils transiently infiltrate intra-Abdominal fat early in the course of high-fat feeding. J Lipid Res 2008;49:1894-1903
-
(2008)
J Lipid Res
, vol.49
, pp. 1894-1903
-
-
Elgazar-Carmon, V.1
Rudich, A.2
Hadad, N.3
Levy, R.4
-
13
-
-
84865992180
-
Natural killer T cells in adipose tissue prevent insulin resistance
-
Schipper HS, Rakhshandehroo M, van de Graaf SF, et al. Natural killer T cells in adipose tissue prevent insulin resistance. J Clin Invest 2012;122:3343-3354
-
(2012)
J Clin Invest
, vol.122
, pp. 3343-3354
-
-
Schipper, H.S.1
Rakhshandehroo, M.2
Van De Graaf, S.F.3
-
14
-
-
84866520055
-
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production
-
Lynch L, Nowak M, Varghese B, et al. Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production. Immunity 2012;37:574-587
-
(2012)
Immunity
, vol.37
, pp. 574-587
-
-
Lynch, L.1
Nowak, M.2
Varghese, B.3
-
15
-
-
84859997837
-
Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity
-
Ji Y, Sun S, Xu A, et al. Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. J Biol Chem 2012;287:13561-13571
-
(2012)
J Biol Chem
, vol.287
, pp. 13561-13571
-
-
Ji, Y.1
Sun, S.2
Xu, A.3
-
16
-
-
84863808516
-
Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4
-
Ji Y, Sun S, Xia S, Yang L, Li X, Qi L. Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4. J Biol Chem 2012;287:24378-24386
-
(2012)
J Biol Chem
, vol.287
, pp. 24378-24386
-
-
Ji, Y.1
Sun, S.2
Xia, S.3
Yang, L.4
Li, X.5
Qi, L.6
-
17
-
-
84871871453
-
A novel function of adipocytes in lipid antigen presentation to iNKT cells
-
Huh JY, Kim JI, Park YJ, et al. A novel function of adipocytes in lipid antigen presentation to iNKT cells. Mol Cell Biol 2013;33:328-339
-
(2013)
Mol Cell Biol
, vol.33
, pp. 328-339
-
-
Huh, J.Y.1
Kim, J.I.2
Park, Y.J.3
-
19
-
-
34250849637
-
Control points in NKT-cell development
-
Godfrey DI, Berzins SP. Control points in NKT-cell development. Nat Rev Immunol 2007;7:505-518
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 505-518
-
-
Godfrey, D.I.1
Berzins, S.P.2
-
20
-
-
0030696696
-
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides
-
Kawano T, Cui J, Koezuka Y, et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 1997;278:1626-1629
-
(1997)
Science
, vol.278
, pp. 1626-1629
-
-
Kawano, T.1
Cui, J.2
Koezuka, Y.3
-
21
-
-
84872943896
-
Invariant natural killer T cells: An innate activation scheme linked to diverse effector functions
-
Brennan PJ, Brigl M, Brenner MB. Invariant natural killer T cells: An innate activation scheme linked to diverse effector functions. Nat Rev Immunol 2013;13: 101-117
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 101-117
-
-
Brennan, P.J.1
Brigl, M.2
Brenner, M.B.3
-
22
-
-
84860794660
-
Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
-
Wu L, Parekh VV, Gabriel CL, et al. Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc Natl Acad Sci U S A 2012;109:E1143-E1152
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E1143-E1152
-
-
Wu, L.1
Parekh, V.V.2
Gabriel, C.L.3
-
23
-
-
84857470273
-
Type II NKT cells stimulate dietinduced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance
-
Satoh M, Andoh Y, Clingan CS, et al. Type II NKT cells stimulate dietinduced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance. PLoS One 2012;7:e30568
-
(2012)
PLoS One
, vol.7
, pp. e30568
-
-
Satoh, M.1
Andoh, Y.2
Clingan, C.S.3
-
24
-
-
84923384136
-
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue
-
Lynch L, Michelet X, Zhang S, et al. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nat Immunol 2015;16:85-95
-
(2015)
Nat Immunol
, vol.16
, pp. 85-95
-
-
Lynch, L.1
Michelet, X.2
Zhang, S.3
-
25
-
-
80053324882
-
Impact of CD1d deficiency on metabolism
-
Kotas ME, Lee HY, Gillum MP, et al. Impact of CD1d deficiency on metabolism. PLoS One 2011;6:e25478
-
(2011)
PLoS One
, vol.6
, pp. e25478
-
-
Kotas, M.E.1
Lee, H.Y.2
Gillum, M.P.3
-
26
-
-
51549107903
-
Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism
-
Cao H, Gerhold K, Mayers JR, Wiest MM, Watkins SM, Hotamisligil GS. Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell 2008;134:933-944
-
(2008)
Cell
, vol.134
, pp. 933-944
-
-
Cao, H.1
Gerhold, K.2
Mayers, J.R.3
Wiest, M.M.4
Watkins, S.M.5
Hotamisligil, G.S.6
-
27
-
-
0027239843
-
Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-Anti-cytokine antibody complexes
-
Finkelman FD, Madden KB, Morris SC, et al. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-Anti-cytokine antibody complexes. J Immunol 1993;151: 1235-1244
-
(1993)
J Immunol
, vol.151
, pp. 1235-1244
-
-
Finkelman, F.D.1
Madden, K.B.2
Morris, S.C.3
-
28
-
-
78651073627
-
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
-
Ricardo-Gonzalez RR, Red Eagle A, Odegaard JI, et al. IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity. Proc Natl Acad Sci U S A 2010;107:22617-22622
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 22617-22622
-
-
Ricardo-Gonzalez, R.R.1
Red Eagle, A.2
Odegaard, J.I.3
-
29
-
-
85060903811
-
Investigation of macrophage polarization using bone marrow derived macrophages
-
Ying W, Cheruku PS, Bazer FW, Safe SH, Zhou B. Investigation of macrophage polarization using bone marrow derived macrophages. J Vis Exp 2013;76: 23851980.
-
(2013)
J Vis Exp
, vol.76
, pp. 23851980
-
-
Ying, W.1
Cheruku, P.S.2
Bazer, F.W.3
Safe, S.H.4
Zhou, B.5
-
30
-
-
84918573907
-
Atypical MHC class II-expressing antigenpresenting cells: Can anything replace a dendritic cell
-
Kambayashi T, Laufer TM. Atypical MHC class II-expressing antigenpresenting cells: can anything replace a dendritic cell? Nat Rev Immunol 2014; 14:719-730
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 719-730
-
-
Kambayashi, T.1
Laufer, T.M.2
-
31
-
-
0037018101
-
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining
-
Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 2002;195:625-636
-
(2002)
J Exp Med
, vol.195
, pp. 625-636
-
-
Gumperz, J.E.1
Miyake, S.2
Yamamura, T.3
Brenner, M.B.4
-
32
-
-
0037265240
-
Alternative activation of macrophages
-
Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003;3: 23-35
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
33
-
-
77954249680
-
Pro-inflammatory CD11c +CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity
-
Wentworth JM, Naselli G, Brown WA, et al. Pro-inflammatory CD11c +CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes 2010;59:1648-1656
-
(2010)
Diabetes
, vol.59
, pp. 1648-1656
-
-
Wentworth, J.M.1
Naselli, G.2
Brown, W.A.3
-
34
-
-
80053406579
-
Inflammation is necessary for long-Term but not short-Term high-fat diet-induced insulin resistance
-
Lee YS, Li P, Huh JY, et al. Inflammation is necessary for long-Term but not short-Term high-fat diet-induced insulin resistance. Diabetes 2011;60:2474-2483
-
(2011)
Diabetes
, vol.60
, pp. 2474-2483
-
-
Lee, Y.S.1
Li, P.2
Huh, J.Y.3
-
35
-
-
77952526597
-
Time-resolved and tissuespecific systems analysis of the pathogenesis of insulin resistance
-
Kleemann R, van Erk M, Verschuren L, et al. Time-resolved and tissuespecific systems analysis of the pathogenesis of insulin resistance. PLoS One 2010;5:e8817
-
(2010)
PLoS One
, vol.5
, pp. e8817
-
-
Kleemann, R.1
Van Erk, M.2
Verschuren, L.3
-
36
-
-
84922569444
-
Lipid signaling in adipose tissue: Connecting inflammation & metabolism
-
Masoodi M, Kuda O, Rossmeisl M, Flachs P, Kopecky J. Lipid signaling in adipose tissue: Connecting inflammation & metabolism. Biochim Biophys Acta 2015;1851:503-518
-
(2015)
Biochim Biophys Acta
, vol.1851
, pp. 503-518
-
-
Masoodi, M.1
Kuda, O.2
Rossmeisl, M.3
Flachs, P.4
Kopecky, J.5
-
37
-
-
84874527555
-
Inflammation during obesity is not all bad: Evidence from animal and human studies
-
Ye J, McGuinness OP. Inflammation during obesity is not all bad: evidence from animal and human studies. Am J Physiol Endocrinol Metab 2013;304:E466-E477
-
(2013)
Am J Physiol Endocrinol Metab
, vol.304
, pp. E466-E477
-
-
Ye, J.1
McGuinness, O.P.2
-
38
-
-
84918843257
-
Metabolism via arginase or nitric oxide synthase: Two competing arginine pathways in macrophages
-
Rath M, Muller I, Kropf P, Closs EI, Munder M. Metabolism via arginase or nitric oxide synthase: Two competing arginine pathways in macrophages. Front Immunol 2014;5:532
-
(2014)
Front Immunol
, vol.5
, pp. 532
-
-
Rath, M.1
Muller, I.2
Kropf, P.3
Closs, E.I.4
Munder, M.5
-
39
-
-
55849130382
-
Macrophage infiltration into adipose tissue: Initiation, propagation and remodeling
-
Surmi BK, Hasty AH. Macrophage infiltration into adipose tissue: initiation, propagation and remodeling. Future Lipidol 2008;3:545-556
-
(2008)
Future Lipidol
, vol.3
, pp. 545-556
-
-
Surmi, B.K.1
Hasty, A.H.2
-
40
-
-
84975780415
-
Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice
-
Satoh M, Hoshino M, Fujita K, et al. Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice. Sci Rep 2016;6:28473
-
(2016)
Sci Rep
, vol.6
, pp. 28473
-
-
Satoh, M.1
Hoshino, M.2
Fujita, K.3
-
41
-
-
79952770879
-
A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells
-
Wun KS, Cameron G, Patel O, et al. A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells. Immunity 2011;34:327-339
-
(2011)
Immunity
, vol.34
, pp. 327-339
-
-
Wun, K.S.1
Cameron, G.2
Patel, O.3
|