-
1
-
-
33947596679
-
The GLUT4 glucose transporter
-
Huang S, Czech MP. The GLUT4 glucose transporter. Cell Metab 2007;5: 237-252
-
(2007)
Cell Metab
, vol.5
, pp. 237-252
-
-
Huang, S.1
Czech, M.P.2
-
2
-
-
0008385878
-
Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site
-
Suzuki K, Kono T. Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site. Proc Natl Acad Sci U S A 1980;77:2542-2545
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 2542-2545
-
-
Suzuki, K.1
Kono, T.2
-
3
-
-
0035825643
-
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
-
Abel ED, Peroni O, Kim JK, et al. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 2001;409:729-733
-
(2001)
Nature
, vol.409
, pp. 729-733
-
-
Abel, E.D.1
Peroni, O.2
Kim, J.K.3
-
4
-
-
0033834248
-
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
-
Zisman A, Peroni OD, Abel ED, et al. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. Nat Med 2000;6:924-928
-
(2000)
Nat Med
, vol.6
, pp. 924-928
-
-
Zisman, A.1
Peroni, O.D.2
Abel, E.D.3
-
5
-
-
1842734654
-
Glucose transporter expression in the central nervous system: Relationship to synaptic function
-
McEwen BS, Reagan LP. Glucose transporter expression in the central nervous system: relationship to synaptic function. Eur J Pharmacol 2004;490: 13-24
-
(2004)
Eur J Pharmacol
, vol.490
, pp. 13-24
-
-
McEwen, B.S.1
Reagan, L.P.2
-
6
-
-
0028040935
-
Glucose transporters (GLUTs 1-4) and their mRNAs in regions of the rat brain: Insulin-sensitive transporter expression in the cerebellum
-
Rayner DV, Thomas ME, Trayhurn P. Glucose transporters (GLUTs 1-4) and their mRNAs in regions of the rat brain: insulin-sensitive transporter expression in the cerebellum. Can J Physiol Pharmacol 1994;72:476-479
-
(1994)
Can J Physiol Pharmacol
, vol.72
, pp. 476-479
-
-
Rayner, D.V.1
Thomas, M.E.2
Trayhurn, P.3
-
7
-
-
0030012543
-
Discrete brain areas express the insulin-responsive glucose transporter GLUT4
-
Leloup C, Arluison M, Kassis N, et al. Discrete brain areas express the insulin-responsive glucose transporter GLUT4. Brain Res Mol Brain Res 1996;38: 45-53
-
(1996)
Brain Res Mol Brain Res
, vol.38
, pp. 45-53
-
-
Leloup, C.1
Arluison, M.2
Kassis, N.3
-
8
-
-
33645883249
-
Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase-dependent mechanism
-
Benomar Y, Naour N, Aubourg A, et al. Insulin and leptin induce Glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3-kinase-dependent mechanism. Endocrinology 2006;147:2550-2556
-
(2006)
Endocrinology
, vol.147
, pp. 2550-2556
-
-
Benomar, Y.1
Naour, N.2
Aubourg, A.3
-
9
-
-
77956367937
-
Brain insulin action regulates hypothalamic glucose sensing and the counterregulatory response to hypoglycemia
-
Diggs-Andrews KA, Zhang X, Song Z, Daphna-Iken D, Routh VH, Fisher SJ. Brain insulin action regulates hypothalamic glucose sensing and the counterregulatory response to hypoglycemia. Diabetes 2010;59:2271-2280
-
(2010)
Diabetes
, vol.59
, pp. 2271-2280
-
-
Diggs-Andrews, K.A.1
Zhang, X.2
Song, Z.3
Daphna-Iken, D.4
Routh, V.H.5
Fisher, S.J.6
-
10
-
-
0032557956
-
GLUT4 glucose transporter expression in rodent brain: Effect of diabetes
-
Vannucci SJ, Koehler-Stec EM, Li K, Reynolds TH, Clark R, Simpson IA. GLUT4 glucose transporter expression in rodent brain: effect of diabetes. Brain Res 1998;797:1-11
-
(1998)
Brain Res
, vol.797
, pp. 1-11
-
-
Vannucci, S.J.1
Koehler-Stec, E.M.2
Li, K.3
Reynolds, T.H.4
Clark, R.5
Simpson, I.A.6
-
11
-
-
1442276966
-
Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons
-
Kang L, Routh VH, Kuzhikandathil EV, Gaspers LD, Levin BE. Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons. Diabetes 2004;53:549-559
-
(2004)
Diabetes
, vol.53
, pp. 549-559
-
-
Kang, L.1
Routh, V.H.2
Kuzhikandathil, E.V.3
Gaspers, L.D.4
Levin, B.E.5
-
12
-
-
0033393822
-
Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart
-
Abel ED, Kaulbach HC, Tian R, et al. Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart. J Clin Invest 1999;104:1703-1714
-
(1999)
J Clin Invest
, vol.104
, pp. 1703-1714
-
-
Abel, E.D.1
Kaulbach, H.C.2
Tian, R.3
-
13
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Bröning JC, Gautam D, Burks DJ, et al. Role of brain insulin receptor in control of body weight and reproduction. Science 2000;289:2122-2125
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bröning, J.C.1
Gautam, D.2
Burks, D.J.3
-
14
-
-
17844391064
-
Insulin signaling in the central nervous system is critical for the normal sympathoadrenal response to hypoglycemia
-
Fisher SJ, Bröning JC, Lannon S, Kahn CR. Insulin signaling in the central nervous system is critical for the normal sympathoadrenal response to hypoglycemia. Diabetes 2005;54:1447-1451
-
(2005)
Diabetes
, vol.54
, pp. 1447-1451
-
-
Fisher, S.J.1
Bröning, J.C.2
Lannon, S.3
Kahn, C.R.4
-
15
-
-
0032842478
-
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
-
Tronche F, Kellendonk C, Kretz O, et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat Genet 1999; 23:99-103
-
(1999)
Nat Genet
, vol.23
, pp. 99-103
-
-
Tronche, F.1
Kellendonk, C.2
Kretz, O.3
-
16
-
-
0037324750
-
Insulin signaling is required for insulins direct and indirect action on hepatic glucose production
-
Fisher SJ, Kahn CR. Insulin signaling is required for insulins direct and indirect action on hepatic glucose production. J Clin Invest 2003;111:463-468
-
(2003)
J Clin Invest
, vol.111
, pp. 463-468
-
-
Fisher, S.J.1
Kahn, C.R.2
-
17
-
-
85047693638
-
Muscle-specific PPARgamma-deficeint mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
-
Norris AW, Chen L, Fisher SJ, et al. Muscle-specific PPARgamma-deficeint mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J Clin Invest 2003;112:608-618
-
(2003)
J Clin Invest
, vol.112
, pp. 608-618
-
-
Norris, A.W.1
Chen, L.2
Fisher, S.J.3
-
18
-
-
0017368491
-
The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat
-
Sokoloff L, Reivich M, Kennedy C, et al. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977; 28:897-916
-
(1977)
J Neurochem
, vol.28
, pp. 897-916
-
-
Sokoloff, L.1
Reivich, M.2
Kennedy, C.3
-
19
-
-
4544383535
-
Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography
-
Toyama H, Ichise M, Liow JS, et al. Absolute quantification of regional cerebral glucose utilization in mice by 18F-FDG small animal PET scanning and 2-14C-DG autoradiography. J Nucl Med 2004;45:1398-1405.
-
(2004)
J Nucl Med
, vol.45
, pp. 1398-1405
-
-
Toyama, H.1
Ichise, M.2
Liow, J.S.3
-
20
-
-
65549109299
-
Brain insulin infusion does not augment the counterregulatory response to hypoglycemia or glucoprivation
-
Ishihara KK, Haywood SC, Daphna-Iken D, Puente EC, Fisher SJ. Brain insulin infusion does not augment the counterregulatory response to hypoglycemia or glucoprivation. Metabolism 2009;58:812-820
-
(2009)
Metabolism
, vol.58
, pp. 812-820
-
-
Ishihara, K.K.1
Haywood, S.C.2
Daphna-Iken, D.3
Puente, E.C.4
Fisher, S.J.5
-
21
-
-
47849111875
-
The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus-potential role in modulation of glucose uptake in neurones?
-
Fernando RN, Albiston AL, Chai SY. The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus-potential role in modulation of glucose uptake in neurones? Eur J Neurosci 2008;28:588-598
-
(2008)
Eur J Neurosci
, vol.28
, pp. 588-598
-
-
Fernando, R.N.1
Albiston, A.L.2
Chai, S.Y.3
-
22
-
-
11244320362
-
A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity
-
Hertel J, Struthers H, Horj CB, Hruz PW. A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity. J Biol Chem 2004; 279:55147-55152
-
(2004)
J Biol Chem
, vol.279
, pp. 55147-55152
-
-
Hertel, J.1
Struthers, H.2
Horj, C.B.3
Hruz, P.W.4
-
23
-
-
0037066357
-
Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations
-
Murata H, Hruz PW, Mueckler M. Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations. AIDS 2002;16:859-863
-
(2002)
AIDS
, vol.16
, pp. 859-863
-
-
Murata, H.1
Hruz, P.W.2
Mueckler, M.3
-
24
-
-
12144275681
-
Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus
-
Song Z, Routh VH. Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 2005;54: 15-22
-
(2005)
Diabetes
, vol.54
, pp. 15-22
-
-
Song, Z.1
Routh, V.H.2
-
25
-
-
33751192694
-
Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus
-
Song Z, Routh VH. Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus. Am J Physiol Regul Integr Comp Physiol 2006;291:R1283-R1287
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
, pp. R1283-R1287
-
-
Song, Z.1
Routh, V.H.2
-
26
-
-
0022189557
-
External and internal standards in the singleisotope derivative (radioenzymatic) measurement of plasma norepinephrine and epinephrine
-
Shah SD, Clutter WE, Cryer PE. External and internal standards in the singleisotope derivative (radioenzymatic) measurement of plasma norepinephrine and epinephrine. J Lab Clin Med 1985;106:624-629
-
(1985)
J Lab Clin Med
, vol.106
, pp. 624-629
-
-
Shah, S.D.1
Clutter, W.E.2
Cryer, P.E.3
-
27
-
-
78650071301
-
Combined neural inactivation of suppressor of cytokine signaling-3 and protein-Tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance
-
Briancon N, McNay DE, Maratos-Flier E, Flier JS. Combined neural inactivation of suppressor of cytokine signaling-3 and protein-Tyrosine phosphatase-1B reveals additive, synergistic, and factor-specific roles in the regulation of body energy balance. Diabetes 2010;59:3074-3084
-
(2010)
Diabetes
, vol.59
, pp. 3074-3084
-
-
Briancon, N.1
McNay, D.E.2
Maratos-Flier, E.3
Flier, J.S.4
-
28
-
-
33746810001
-
Neuronal PTP1B regulates body weight, adiposity and leptin action
-
Bence KK, Delibegovic M, Xue B, et al. Neuronal PTP1B regulates body weight, adiposity and leptin action. Nat Med 2006;12:917-924
-
(2006)
Nat Med
, vol.12
, pp. 917-924
-
-
Bence, K.K.1
Delibegovic, M.2
Xue, B.3
-
29
-
-
77955405459
-
Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland
-
Galichet C, Lovell-Badge R, Rizzoti K. Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland. PLoS One 2010;5:e11443
-
(2010)
PLoS One
, vol.5
, pp. e11443
-
-
Galichet, C.1
Lovell-Badge, R.2
Rizzoti, K.3
-
30
-
-
84921918075
-
Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons
-
Ren H, Lu TY, McGraw TE, Accili D. Anorexia and impaired glucose metabolism in mice with hypothalamic ablation of Glut4 neurons. Diabetes 2015;64:405-417
-
(2015)
Diabetes
, vol.64
, pp. 405-417
-
-
Ren, H.1
Lu, T.Y.2
McGraw, T.E.3
Accili, D.4
-
32
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
Obici S, Zhang BB, Karkanias G, Rossetti L. Hypothalamic insulin signaling is required for inhibition of glucose production. Nat Med 2002;8:1376-1382
-
(2002)
Nat Med
, vol.8
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
34
-
-
77953183468
-
Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo
-
Paranjape SA, Chan O, Zhu W, et al. Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo. Diabetes 2010;59:1521-1527
-
(2010)
Diabetes
, vol.59
, pp. 1521-1527
-
-
Paranjape, S.A.1
Chan, O.2
Zhu, W.3
-
35
-
-
79952428530
-
Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues
-
Lin HV, Ren H, Samuel VT, et al. Diabetes in mice with selective impairment of insulin action in Glut4-expressing tissues. Diabetes 2011;60:700-709
-
(2011)
Diabetes
, vol.60
, pp. 700-709
-
-
Lin, H.V.1
Ren, H.2
Samuel, V.T.3
-
37
-
-
33646536045
-
I.C.V. Administration of the nonsteroidal glucocorticoid receptor antagonist, CP-472555, prevents exacerbated hypoglycemia during repeated insulin administration
-
Kale AY, Paranjape SA, Briski KP. I.c.v. administration of the nonsteroidal glucocorticoid receptor antagonist, CP-472555, prevents exacerbated hypoglycemia during repeated insulin administration. Neuroscience 2006;140:555-565
-
(2006)
Neuroscience
, vol.140
, pp. 555-565
-
-
Kale, A.Y.1
Paranjape, S.A.2
Briski, K.P.3
-
38
-
-
0028865816
-
Induction of Fos protein in the rat hypothalamus elicited by insulin-induced hypoglycemia
-
Niimi M, Sato M, Tamaki M, Wada Y, Takahara J, Kawanishi K. Induction of Fos protein in the rat hypothalamus elicited by insulin-induced hypoglycemia. Neurosci Res 1995;23:361-364
-
(1995)
Neurosci Res
, vol.23
, pp. 361-364
-
-
Niimi, M.1
Sato, M.2
Tamaki, M.3
Wada, Y.4
Takahara, J.5
Kawanishi, K.6
-
39
-
-
34248204584
-
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: Integration in neuropeptide y and pro-opio melanocortin networks?
-
Fioramonti X, Contié S, Song Z, Routh VH, Lorsignol A, Pénicaud L. Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks? Diabetes 2007; 56:1219-1227
-
(2007)
Diabetes
, vol.56
, pp. 1219-1227
-
-
Fioramonti, X.1
Contié, S.2
Song, Z.3
Routh, V.H.4
Lorsignol, A.5
Pénicaud, L.6
-
40
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y, Alquier T, Furukawa N, et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004;428:569-574
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, N.3
-
41
-
-
70349244719
-
AMP-Activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons
-
Murphy BA, Fakira KA, Song Z, Beuve A, Routh VH. AMP-Activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons. Am J Physiol Cell Physiol 2009;297:C750-C758
-
(2009)
Am J Physiol Cell Physiol
, vol.297
, pp. C750-C758
-
-
Murphy, B.A.1
Fakira, K.A.2
Song, Z.3
Beuve, A.4
Routh, V.H.5
-
42
-
-
0033944152
-
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats
-
Spanswick D, Smith MA, Mirshamsi S, Routh VH, Ashford ML. Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats. Nat Neurosci 2000;3:757-758
-
(2000)
Nat Neurosci
, vol.3
, pp. 757-758
-
-
Spanswick, D.1
Smith, M.A.2
Mirshamsi, S.3
Routh, V.H.4
Ashford, M.L.5
-
43
-
-
66149083518
-
Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose
-
Cotero VE, Routh VH. Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose. Am J Physiol Endocrinol Metab 2009;296:E1101-E1109
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, pp. E1101-E1109
-
-
Cotero, V.E.1
Routh, V.H.2
|