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Volumn 66, Issue 4, 2017, Pages 815-822

Role of adipose tissue insulin resistance in the natural history of type 2 diabetes: Results from the san antonio metabolism study

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; FATTY ACID; GLUCOSE BLOOD LEVEL;

EID: 85019562792     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db16-1167     Document Type: Article
Times cited : (243)

References (41)
  • 2
    • 33747356154 scopus 로고    scopus 로고
    • Adipose tissue: From lipid storage compartment to endocrine organ
    • Scherer PE. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 2006;55:1537-1545
    • (2006) Diabetes , vol.55 , pp. 1537-1545
    • Scherer, P.E.1
  • 3
    • 33644746318 scopus 로고    scopus 로고
    • Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle
    • Brehm A, Krssak M, Schmid AI, Nowotny P, Waldhäusl W, Roden M. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes 2006;55:136-140
    • (2006) Diabetes , vol.55 , pp. 136-140
    • Brehm, A.1    Krssak, M.2    Schmid, A.I.3    Nowotny, P.4    Waldhäusl, W.5    Roden, M.6
  • 4
    • 84969812000 scopus 로고    scopus 로고
    • The multifaceted roles of adipose tissue-Therapeutic targets for diabetes and beyond: The 2015
    • Scherer PE. The multifaceted roles of adipose tissue-Therapeutic targets for diabetes and beyond: The 2015 Banting Lecture. Diabetes 2016;65:1452-1461
    • (2016) Banting Lecture Diabetes , Issue.65 , pp. 1452-1461
    • Scherer, P.E.1
  • 5
    • 84907977576 scopus 로고    scopus 로고
    • A missing link in body weight homeostasis: The catabolic signal of the overfed state
    • Ravussin Y, Leibel RL, Ferrante AW Jr. A missing link in body weight homeostasis: The catabolic signal of the overfed state. Cell Metab 2014;20:565-572
    • (2014) Cell Metab , vol.20 , pp. 565-572
    • Ravussin, Y.1    Leibel, R.L.2    Ferrante, A.W.3
  • 6
    • 84947268804 scopus 로고    scopus 로고
    • The subtle balance between lipolysis and lipogenesis: A critical point in metabolic homeostasis
    • Saponaro C, Gaggini M, Carli F, Gastaldelli A. The subtle balance between lipolysis and lipogenesis: A critical point in metabolic homeostasis. Nutrients 2015;7:9453-9474
    • (2015) Nutrients , vol.7 , pp. 9453-9474
    • Saponaro, C.1    Gaggini, M.2    Carli, F.3    Gastaldelli, A.4
  • 8
    • 84921914861 scopus 로고    scopus 로고
    • Vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans
    • Allister CA, Liu LF, Lamendola CA, et al. In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans. J Lipid Res 2015;56:435-439
    • (2015) J Lipid Res , vol.56 , pp. 435-439
    • Allister, C.A.1    Liu, L.F.2    Lamendola, C.A.3
  • 9
    • 0029948212 scopus 로고    scopus 로고
    • Mechanism of free fatty acid-induced insulin resistance in humans
    • Roden M, Price TB, Perseghin G, et al. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996;97:2859-2865
    • (1996) J Clin Invest , vol.97 , pp. 2859-2865
    • Roden, M.1    Price, T.B.2    Perseghin, G.3
  • 10
    • 20044390768 scopus 로고    scopus 로고
    • Dose-response effect of elevated plasma free fatty acid on insulin signaling
    • Belfort R, Mandarino L, Kashyap S, et al. Dose-response effect of elevated plasma free fatty acid on insulin signaling. Diabetes 2005;54:1640-1648
    • (2005) Diabetes , vol.54 , pp. 1640-1648
    • Belfort, R.1    Mandarino, L.2    Kashyap, S.3
  • 11
    • 0141755328 scopus 로고    scopus 로고
    • A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes
    • Kashyap S, Belfort R, Gastaldelli A, et al. A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes. Diabetes 2003;52:2461-2474
    • (2003) Diabetes , vol.52 , pp. 2461-2474
    • Kashyap, S.1    Belfort, R.2    Gastaldelli, A.3
  • 13
    • 0034072554 scopus 로고    scopus 로고
    • Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans
    • Roden M, Stingl H, Chandramouli V, et al. Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans. Diabetes 2000;49:701-707
    • (2000) Diabetes , vol.49 , pp. 701-707
    • Roden, M.1    Stingl, H.2    Chandramouli, V.3
  • 15
    • 84945570919 scopus 로고    scopus 로고
    • Saturation of subcutaneous adipose tissue expansion and accumulation of ectopic fat associated with metabolic dysfunction during late and post-pubertal growth
    • Gyllenhammer LE, Alderete TL, Toledo-Corral CM, Weigensberg M, Goran MI. Saturation of subcutaneous adipose tissue expansion and accumulation of ectopic fat associated with metabolic dysfunction during late and post-pubertal growth. Int J Obes 2016;40:601-606
    • (2016) Int J Obes , vol.40 , pp. 601-606
    • Gyllenhammer, L.E.1    Alderete, T.L.2    Toledo-Corral, C.M.3    Weigensberg, M.4    Goran, M.I.5
  • 16
    • 84916608249 scopus 로고    scopus 로고
    • Effects of increased free fatty acid availability on adipose tissue fatty acid storage in men
    • Mundi MS, Koutsari C, Jensen MD. Effects of increased free fatty acid availability on adipose tissue fatty acid storage in men. J Clin Endocrinol Metab 2014;99:E2635-E2642
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E2635-E2642
    • Mundi, M.S.1    Koutsari, C.2    Jensen, M.D.3
  • 17
    • 84855678225 scopus 로고    scopus 로고
    • Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects
    • Fabbrini E, Magkos F, Conte C, et al. Validation of a novel index to assess insulin resistance of adipose tissue lipolytic activity in obese subjects. J Lipid Res 2012;53:321-324
    • (2012) J Lipid Res , vol.53 , pp. 321-324
    • Fabbrini, E.1    Magkos, F.2    Conte, C.3
  • 18
    • 0024392514 scopus 로고
    • Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance
    • Groop LC, Bonadonna RC, DelPrato S, et al. Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance. J Clin Invest 1989;84:205-213
    • (1989) J Clin Invest , vol.84 , pp. 205-213
    • Groop, L.C.1    Bonadonna, R.C.2    Delprato, S.3
  • 19
    • 0031958586 scopus 로고    scopus 로고
    • Effect of insulin on glycerol production in obese adolescents
    • Robinson C, Tamborlane WV, Maggs DG, et al. Effect of insulin on glycerol production in obese adolescents. Am J Physiol 1998;274:E737-E743
    • (1998) Am J Physiol , vol.274 , pp. E737-E743
    • Robinson, C.1    Tamborlane, W.V.2    Maggs, D.G.3
  • 20
    • 67650093467 scopus 로고    scopus 로고
    • Decreased whole body lipolysis as a mechanism of the lipid-lowering effect of pioglitazone in type 2 diabetic patients
    • Gastaldelli A, Casolaro A, Ciociaro D, et al. Decreased whole body lipolysis as a mechanism of the lipid-lowering effect of pioglitazone in type 2 diabetic patients. Am J Physiol Endocrinol Metab 2009;297:E225-E230
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , pp. E225-E230
    • Gastaldelli, A.1    Casolaro, A.2    Ciociaro, D.3
  • 21
    • 84980037565 scopus 로고    scopus 로고
    • Quantification of adipose tissue insulin sensitivity
    • Søndergaard E, Jensen MD. Quantification of adipose tissue insulin sensitivity. J Investig Med 2016;64:989-991
    • (2016) J Investig Med , vol.64 , pp. 989-991
    • Søndergaard, E.1    Jensen, M.D.2
  • 22
    • 80053408094 scopus 로고    scopus 로고
    • Fatty acids, obesity, and insulin resistance: Time for a reevaluation
    • Karpe F, Dickmann JR, Frayn KN. Fatty acids, obesity, and insulin resistance: Time for a reevaluation. Diabetes 2011;60:2441-2449
    • (2011) Diabetes , vol.60 , pp. 2441-2449
    • Karpe, F.1    Dickmann, J.R.2    Frayn, K.N.3
  • 23
    • 77951634226 scopus 로고    scopus 로고
    • Insulin resistance, adipose depots and gut: Interactions and pathological implications
    • Gastaldelli A, Natali A, Vettor R, Corradini SG. Insulin resistance, adipose depots and gut: interactions and pathological implications. Dig Liver Dis 2010; 42:310-319
    • (2010) Dig Liver Dis , vol.42 , pp. 310-319
    • Gastaldelli, A.1    Natali, A.2    Vettor, R.3    Corradini, S.G.4
  • 24
    • 33845231987 scopus 로고    scopus 로고
    • Insulin dose response analysis of free fatty acid kinetics
    • Jensen MD, Nielsen S. Insulin dose response analysis of free fatty acid kinetics. Metabolism 2007;56:68-76
    • (2007) Metabolism , vol.56 , pp. 68-76
    • Jensen, M.D.1    Nielsen, S.2
  • 25
    • 0036260039 scopus 로고    scopus 로고
    • Sensitivity to acute insulin-mediated suppression of plasma free fatty acids is not a determinant of fasting VLDL triglyceride secretion in healthy humans
    • Carpentier A, Patterson BW, Leung N, Lewis GF. Sensitivity to acute insulin-mediated suppression of plasma free fatty acids is not a determinant of fasting VLDL triglyceride secretion in healthy humans. Diabetes 2002;51: 1867-1875
    • (2002) Diabetes , vol.51 , pp. 1867-1875
    • Carpentier, A.1    Patterson, B.W.2    Leung, N.3    Lewis, G.F.4
  • 26
    • 20944450486 scopus 로고    scopus 로고
    • Insulin resistance in non-diabetic patients with non-Alcoholic fatty liver disease: Sites and mechanisms
    • Bugianesi E, Gastaldelli A, Vanni E, et al. Insulin resistance in non-diabetic patients with non-Alcoholic fatty liver disease: sites and mechanisms. Diabetologia 2005;48:634-642
    • (2005) Diabetologia , vol.48 , pp. 634-642
    • Bugianesi, E.1    Gastaldelli, A.2    Vanni, E.3
  • 27
    • 34547514221 scopus 로고    scopus 로고
    • Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
    • Gastaldelli A, Cusi K, Pettiti M, et al. Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology 2007;133:496-506
    • (2007) Gastroenterology , vol.133 , pp. 496-506
    • Gastaldelli, A.1    Cusi, K.2    Pettiti, M.3
  • 28
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
    • Lomonaco R, Ortiz-Lopez C, Orsak B, et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. Hepatology 2012;55:1389-1397
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3
  • 29
    • 84903144240 scopus 로고    scopus 로고
    • Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-Alcoholic steatohepatitis
    • Armstrong MJ, Hazlehurst JM, Hull D, et al. Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-Alcoholic steatohepatitis. Diabetes Obes Metab 2014;16:651-660
    • (2014) Diabetes Obes Metab , vol.16 , pp. 651-660
    • Armstrong, M.J.1    Hazlehurst, J.M.2    Hull, D.3
  • 30
    • 84867200413 scopus 로고    scopus 로고
    • Nonalcoholic Steatohepatitis Clinical Research Network. Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: A pioglitazone versus vitamin e versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study
    • Bell LN, Wang J, Muralidharan S, et al.; Nonalcoholic Steatohepatitis Clinical Research Network. Relationship between adipose tissue insulin resistance and liver histology in nonalcoholic steatohepatitis: A pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis trial follow-up study. Hepatology 2012;56:1311-1318
    • (2012) Hepatology , vol.56 , pp. 1311-1318
    • Bell, L.N.1    Wang, J.2    Muralidharan, S.3
  • 31
    • 0942279564 scopus 로고    scopus 로고
    • San antonio metabolism study beta-cell dysfunction and glucose intolerance: Results from the san antonio metabolism (sam) study
    • Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA; San Antonio Metabolism Study. Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia 2004;47:31-39
    • (2004) Diabetologia , vol.47 , pp. 31-39
    • Gastaldelli, A.1    Ferrannini, E.2    Miyazaki, Y.3    Matsuda, M.4    Defronzo, R.A.5
  • 32
    • 0032821965 scopus 로고    scopus 로고
    • Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
    • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22:1462-1470
    • (1999) Diabetes Care , vol.22 , pp. 1462-1470
    • Matsuda, M.1    Defronzo, R.A.2
  • 33
  • 34
    • 64649104158 scopus 로고    scopus 로고
    • Banting lecture from the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • Defronzo RA. Banting Lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 2009;58:773-795
    • (2009) Diabetes , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 37
    • 84891451520 scopus 로고    scopus 로고
    • Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men
    • Mahendran Y, Cederberg H, Vangipurapu J, et al. Glycerol and fatty acids in serum predict the development of hyperglycemia and type 2 diabetes in Finnish men. Diabetes Care 2013;36:3732-3738
    • (2013) Diabetes Care , vol.36 , pp. 3732-3738
    • Mahendran, Y.1    Cederberg, H.2    Vangipurapu, J.3
  • 38
    • 84891845753 scopus 로고    scopus 로고
    • Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk
    • ACT NOW Study
    • Defronzo RA, Tripathy D, Schwenke DC, et al.; ACT NOW Study. Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk. Diabetes Care 2013;36:3607-3612
    • (2013) Diabetes Care , vol.36 , pp. 3607-3612
    • Defronzo, R.A.1    Tripathy, D.2    Schwenke, D.C.3
  • 39
    • 80052547130 scopus 로고    scopus 로고
    • Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: The RISC Study
    • RISC Investigators
    • Ferrannini E, Natali A, Muscelli E, et al.; RISC Investigators. Natural history and physiological determinants of changes in glucose tolerance in a non-diabetic population: The RISC Study. Diabetologia 2011;54: 1507-1516
    • (2011) Diabetologia , vol.54 , pp. 1507-1516
    • Ferrannini, E.1    Natali, A.2    Muscelli, E.3
  • 40
    • 84896495719 scopus 로고    scopus 로고
    • Pathophysiology and treatment of type 2 diabetes: Perspectives on the past, present, and future
    • Kahn SE, Cooper ME, Del Prato S. Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. Lancet 2014;383:1068-1083
    • (2014) Lancet , vol.383 , pp. 1068-1083
    • Kahn, S.E.1    Cooper, M.E.2    Del Prato, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.