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Volumn 16, Issue 7, 2014, Pages 651-660

Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis

Author keywords

Adipose tissue; Fatty liver; Insulin sensitivity; Lipolysis; Steatohepatitis

Indexed keywords

ADIPOCYTOKINE; CARBOHYDRATE; GLICLAZIDE; GLUCOSE; GLYCEROL; INSULIN; LIPID; METFORMIN; NEUTRAL INSULIN; STABLE ISOTOPE; ANTIDIABETIC AGENT; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

EID: 84903144240     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.12272     Document Type: Article
Times cited : (51)

References (40)
  • 1
    • 84878930738 scopus 로고    scopus 로고
    • Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
    • Anstee QM, Targher G, Day CP. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol 2013; 10: 330-344.
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 330-344
    • Anstee, Q.M.1    Targher, G.2    Day, C.P.3
  • 3
    • 84863489710 scopus 로고    scopus 로고
    • Increased risk of cardiovascular disease and chronic kidney disease in NAFLD
    • Bonora E, Targher G. Increased risk of cardiovascular disease and chronic kidney disease in NAFLD. Nat Rev Gastroenterol Hepatol 2012; 9: 372-381.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 372-381
    • Bonora, E.1    Targher, G.2
  • 4
    • 18244364864 scopus 로고    scopus 로고
    • NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome
    • Chitturi S, Abeygunasekera S, Farrell GC et al. NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002; 35: 373-379.
    • (2002) Hepatology , vol.35 , pp. 373-379
    • Chitturi, S.1    Abeygunasekera, S.2    Farrell, G.C.3
  • 5
    • 0035431018 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: a feature of the metabolic syndrome
    • Marchesini G, Brizi M, Bianchi G et al. Nonalcoholic fatty liver disease: a feature of the metabolic syndrome. Diabetes 2001; 50: 1844-1850.
    • (2001) Diabetes , vol.50 , pp. 1844-1850
    • Marchesini, G.1    Brizi, M.2    Bianchi, G.3
  • 6
    • 0035084699 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities
    • Sanyal AJ, Campbell-Sargent C, Mirshahi F et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001; 120: 1183-1192.
    • (2001) Gastroenterology , vol.120 , pp. 1183-1192
    • Sanyal, A.J.1    Campbell-Sargent, C.2    Mirshahi, F.3
  • 7
    • 20944450486 scopus 로고    scopus 로고
    • Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
    • Bugianesi E, Gastaldelli A, Vanni E et al. Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms. Diabetologia 2005; 48: 634-642.
    • (2005) Diabetologia , vol.48 , pp. 634-642
    • Bugianesi, E.1    Gastaldelli, A.2    Vanni, E.3
  • 8
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
    • Lomonaco R, Ortiz-Lopez C, Orsak B et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. Hepatology 2012; 55: 1389-1397.
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3
  • 9
    • 84859393575 scopus 로고    scopus 로고
    • Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD)
    • Ortiz-Lopez C, Lomonaco R, Orsak B et al. Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). Diabetes Care 2012; 35: 873-878.
    • (2012) Diabetes Care , vol.35 , pp. 873-878
    • Ortiz-Lopez, C.1    Lomonaco, R.2    Orsak, B.3
  • 10
    • 33646035836 scopus 로고    scopus 로고
    • Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states
    • Barrows BR, Parks EJ. Contributions of different fatty acid sources to very low-density lipoprotein-triacylglycerol in the fasted and fed states. J Clin Endocrinol Metab 2006; 91: 1446-1452.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1446-1452
    • Barrows, B.R.1    Parks, E.J.2
  • 11
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005; 115: 1343-1351.
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 12
    • 84865553250 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis versus steatosis: adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism
    • Musso G, Cassader M, De Michieli F, Rosina F, Orlandi F, Gambino R. Nonalcoholic steatohepatitis versus steatosis: adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism. Hepatology 2012; 56: 933-942.
    • (2012) Hepatology , vol.56 , pp. 933-942
    • Musso, G.1    Cassader, M.2    De Michieli, F.3    Rosina, F.4    Orlandi, F.5    Gambino, R.6
  • 13
    • 70350064027 scopus 로고    scopus 로고
    • Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis
    • Gastaldelli A, Harrison SA, Belfort-Aguilar R et al. Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis. Hepatology 2009; 50: 1087-1093.
    • (2009) Hepatology , vol.50 , pp. 1087-1093
    • Gastaldelli, A.1    Harrison, S.A.2    Belfort-Aguilar, R.3
  • 14
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications
    • Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. Gastroenterology 2012; 142: 711-725.e716.
    • (2012) Gastroenterology , vol.142
    • Cusi, K.1
  • 15
    • 38649111018 scopus 로고    scopus 로고
    • Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
    • Fabbrini E, Mohammed BS, Magkos F, Korenblat KM, Patterson BW, Klein S. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology 2008; 134: 424-431.
    • (2008) Gastroenterology , vol.134 , pp. 424-431
    • Fabbrini, E.1    Mohammed, B.S.2    Magkos, F.3    Korenblat, K.M.4    Patterson, B.W.5    Klein, S.6
  • 16
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 2007; 56: 1010-1013.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 17
    • 67649380355 scopus 로고    scopus 로고
    • Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status
    • Tordjman J, Poitou C, Hugol D et al. Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status. J Hepatol 2009; 51: 354-362.
    • (2009) J Hepatol , vol.51 , pp. 354-362
    • Tordjman, J.1    Poitou, C.2    Hugol, D.3
  • 18
    • 4544369644 scopus 로고    scopus 로고
    • Regional adiposity and insulin resistance
    • Garg A. Regional adiposity and insulin resistance. J Clin Endocrinol Metab 2004; 89: 4206-4210.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4206-4210
    • Garg, A.1
  • 20
    • 0029862540 scopus 로고    scopus 로고
    • Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM
    • Abate N, Garg A, Peshock RM, Stray-Gundersen J, Adams-Huet B, Grundy SM. Relationship of generalized and regional adiposity to insulin sensitivity in men with NIDDM. Diabetes 1996; 45: 1684-1693.
    • (1996) Diabetes , vol.45 , pp. 1684-1693
    • Abate, N.1    Garg, A.2    Peshock, R.M.3    Stray-Gundersen, J.4    Adams-Huet, B.5    Grundy, S.M.6
  • 21
    • 0029087640 scopus 로고
    • Relationships of generalized and regional adiposity to insulin sensitivity in men
    • Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM. Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest 1995; 96: 88-98.
    • (1995) J Clin Invest , vol.96 , pp. 88-98
    • Abate, N.1    Garg, A.2    Peshock, R.M.3    Stray-Gundersen, J.4    Grundy, S.M.5
  • 22
    • 17744378195 scopus 로고    scopus 로고
    • Study AGaHL. The metabolic syndrome, cardiopulmonary fitness, and subcutaneous trunk fat as independent determinants of arterial stiffness: the Amsterdam Growth and Health Longitudinal Study
    • Ferreira I, Henry RMA, Twisk JWR, van Mechelen W, Kemper HCG, Stehouwer CDA. Study AGaHL. The metabolic syndrome, cardiopulmonary fitness, and subcutaneous trunk fat as independent determinants of arterial stiffness: the Amsterdam Growth and Health Longitudinal Study. Arch Intern Med 2005; 165: 875-882.
    • (2005) Arch Intern Med , vol.165 , pp. 875-882
    • Ferreira, I.1    Henry, R.M.A.2    Twisk, J.W.R.3    van Mechelen, W.4    Kemper, H.C.G.5    Stehouwer, C.D.A.6
  • 23
    • 0030765908 scopus 로고    scopus 로고
    • Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat
    • Goodpaster BH, Thaete FL, Simoneau JA, Kelley DE. Subcutaneous abdominal fat and thigh muscle composition predict insulin sensitivity independently of visceral fat. Diabetes 1997; 46: 1579-1585.
    • (1997) Diabetes , vol.46 , pp. 1579-1585
    • Goodpaster, B.H.1    Thaete, F.L.2    Simoneau, J.A.3    Kelley, D.E.4
  • 24
    • 79959573040 scopus 로고    scopus 로고
    • Endpoints and clinical trial design for nonalcoholic steatohepatitis
    • Sanyal AJ, Brunt EM, Kleiner DE et al. Endpoints and clinical trial design for nonalcoholic steatohepatitis. Hepatology 2011; 54: 344-353.
    • (2011) Hepatology , vol.54 , pp. 344-353
    • Sanyal, A.J.1    Brunt, E.M.2    Kleiner, D.E.3
  • 25
    • 69249087403 scopus 로고    scopus 로고
    • Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors
    • Kotronen A, Peltonen M, Hakkarainen A et al. Prediction of non-alcoholic fatty liver disease and liver fat using metabolic and genetic factors. Gastroenterology 2009; 137: 865-872.
    • (2009) Gastroenterology , vol.137 , pp. 865-872
    • Kotronen, A.1    Peltonen, M.2    Hakkarainen, A.3
  • 26
    • 0008482593 scopus 로고
    • Use of C14-glucose to measure hepatic glucose production following an intravenous glucose load or after injection of insulin
    • Steele R. Use of C14-glucose to measure hepatic glucose production following an intravenous glucose load or after injection of insulin. Metabolism 1959; 8: 512-519.
    • (1959) Metabolism , vol.8 , pp. 512-519
    • Steele, R.1
  • 27
    • 0023245416 scopus 로고
    • Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates
    • Finegood DT, Bergman RN, Vranic M. Estimation of endogenous glucose production during hyperinsulinemic-euglycemic glucose clamps. Comparison of unlabeled and labeled exogenous glucose infusates. Diabetes 1987; 36: 914-924.
    • (1987) Diabetes , vol.36 , pp. 914-924
    • Finegood, D.T.1    Bergman, R.N.2    Vranic, M.3
  • 28
    • 84876263472 scopus 로고    scopus 로고
    • Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo
    • Hazlehurst JM, Gathercole LL, Nasiri M et al. Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo. J Clin Endocrinol Metab 2013; 98: 1631-1640.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 1631-1640
    • Hazlehurst, J.M.1    Gathercole, L.L.2    Nasiri, M.3
  • 29
    • 0029888309 scopus 로고    scopus 로고
    • In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated
    • Diraison F, Pachiaudi C, Beylot M. In vivo measurement of plasma cholesterol and fatty acid synthesis with deuterated water: determination of the average number of deuterium atoms incorporated. Metabolism 1996; 45: 817-821.
    • (1996) Metabolism , vol.45 , pp. 817-821
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 30
    • 0031033070 scopus 로고    scopus 로고
    • Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: use of simple gas chromatographic/mass spectrometric techniques
    • Diraison F, Pachiaudi C, Beylot M. Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: use of simple gas chromatographic/mass spectrometric techniques. J Mass Spectrom 1997; 32: 81-86.
    • (1997) J Mass Spectrom , vol.32 , pp. 81-86
    • Diraison, F.1    Pachiaudi, C.2    Beylot, M.3
  • 31
    • 34547514221 scopus 로고    scopus 로고
    • Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
    • Gastaldelli A, Cusi K, Pettiti M et al. Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology 2007; 133: 496-506.
    • (2007) Gastroenterology , vol.133 , pp. 496-506
    • Gastaldelli, A.1    Cusi, K.2    Pettiti, M.3
  • 32
    • 80052032690 scopus 로고    scopus 로고
    • Role of ethnicity in overweight and obese patients with nonalcoholic steatohepatitis
    • Lomonaco R, Ortiz-Lopez C, Orsak B et al. Role of ethnicity in overweight and obese patients with nonalcoholic steatohepatitis. Hepatology 2011; 54: 837-845.
    • (2011) Hepatology , vol.54 , pp. 837-845
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3
  • 33
    • 13744263104 scopus 로고    scopus 로고
    • Temporal pattern of de novo lipogenesis in the postprandial state in healthy men
    • Timlin MT, Parks EJ. Temporal pattern of de novo lipogenesis in the postprandial state in healthy men. Am J Clin Nutr 2005; 81: 35-42.
    • (2005) Am J Clin Nutr , vol.81 , pp. 35-42
    • Timlin, M.T.1    Parks, E.J.2
  • 34
    • 0344874201 scopus 로고    scopus 로고
    • Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease
    • Diraison F, Moulin P, Beylot M. Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease. Diabetes Metab 2003; 29: 478-485.
    • (2003) Diabetes Metab , vol.29 , pp. 478-485
    • Diraison, F.1    Moulin, P.2    Beylot, M.3
  • 35
    • 24144441285 scopus 로고    scopus 로고
    • Point: visceral adiposity is causally related to insulin resistance
    • Lebovitz HE, Banerji MA. Point: visceral adiposity is causally related to insulin resistance. Diabetes Care 2005; 28: 2322-2325.
    • (2005) Diabetes Care , vol.28 , pp. 2322-2325
    • Lebovitz, H.E.1    Banerji, M.A.2
  • 36
    • 24144473122 scopus 로고    scopus 로고
    • Counterpoint: visceral adiposity is not causally related to insulin resistance
    • Miles JM, Jensen MD. Counterpoint: visceral adiposity is not causally related to insulin resistance. Diabetes Care 2005; 28: 2326-2328.
    • (2005) Diabetes Care , vol.28 , pp. 2326-2328
    • Miles, J.M.1    Jensen, M.D.2
  • 37
    • 80053408094 scopus 로고    scopus 로고
    • Fatty acids, obesity, and insulin resistance: time for a reevaluation
    • Karpe F, Dickmann JR, Frayn KN. Fatty acids, obesity, and insulin resistance: time for a reevaluation. Diabetes 2011; 60: 2441-2449.
    • (2011) Diabetes , vol.60 , pp. 2441-2449
    • Karpe, F.1    Dickmann, J.R.2    Frayn, K.N.3
  • 38
    • 84859701943 scopus 로고    scopus 로고
    • Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity
    • Tordjman J, Divoux A, Prifti E et al. Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity. J Hepatol 2012; 56: 1152-1158.
    • (2012) J Hepatol , vol.56 , pp. 1152-1158
    • Tordjman, J.1    Divoux, A.2    Prifti, E.3
  • 39
    • 84877261259 scopus 로고    scopus 로고
    • Role of subcutaneous adipose tissue in the pathogenesis of insulin resistance
    • Patel P, Abate N. Role of subcutaneous adipose tissue in the pathogenesis of insulin resistance. J Obes. 2013; 2013: 489187.
    • (2013) J Obes. , vol.2013 , pp. 489187
    • Patel, P.1    Abate, N.2
  • 40
    • 78049277828 scopus 로고    scopus 로고
    • Association of pericardial fat with liver fat and insulin sensitivity after diet-induced weight loss in overweight women
    • Bosy-Westphal A, Kossel E, Goele K et al. Association of pericardial fat with liver fat and insulin sensitivity after diet-induced weight loss in overweight women. Obesity 2010; 18: 2111-2117.
    • (2010) Obesity , vol.18 , pp. 2111-2117
    • Bosy-Westphal, A.1    Kossel, E.2    Goele, K.3


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