TIR-domain-containing adapter-inducing interferon-β (TRIF) forms filamentous structures, whose pro-apoptotic signalling is terminated by autophagy

FEBS Journal

Volumn 284, Issue 13, 2017, Pages 1987-2003

  Gentle, Ian E ^a   McHenry, Kevin T ^b   Weber, Arnim ^a   Metz, Arlena ^a   Kretz, Oliver ^a,c   Porter, Dale ^b   Häcker, Georg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

apoptosis; autophagy; fibril; melanoma; TRIF

Indexed keywords

CASPASE 8; INHIBITOR OF APOPTOSIS PROTEIN; INTERLEUKIN 1 RECEPTOR; PHOSPHOTRANSFERASE; RECEPTOR INTERACTING KINASE 1; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; LBW242; OLIGOPEPTIDE; POLYINOSINIC POLYCYTIDYLIC ACID; RECEPTOR INTERACTING PROTEIN SERINE THREONINE KINASE; RIPK1 PROTEIN, HUMAN; TICAM1 PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BIOACCUMULATION; CELL ACTIVATION; CONTROLLED STUDY; FIBER; HUMAN; HUMAN CELL; INNATE IMMUNITY; MELANOMA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE MICROSCOPY; GENETICS; HEK293 CELL LINE; HELA CELL LINE; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE; WESTERN BLOTTING;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CASPASE 8; CELL LINE, TUMOR; CELLS, CULTURED; HEK293 CELLS; HELA CELLS; HUMANS; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; OLIGOPEPTIDES; POLY I-C; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3;

EID: 85019345261     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.14091     Document Type: Article

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