Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway

Cell Reports

Volumn 19, Issue 7, 2017, Pages 1418-1430

  Gaudet, Ryan G ^a,d   Guo, Cynthia X ^a   Molinaro, Raphael ^a   Kottwitz, Haila ^b   Rohde, John R ^b   Dangeard, Anne Sophie ^c   Arrieumerlou, Cécile ^c   Girardin, Stephen E ^a   Gray Owen, Scott D ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

^c INSERM   (France)

^d YALE UNIVERSITY   (United States)

Author keywords

heptose; inflammation; innate immunity; intracellular bacteria; NOD like receptors; PAMP; pattern recognition; Shigella; TIFA

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; HEPATOSE 1,7 BISPHOSPHATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MEMBRANE PROTEIN; MYELOID DIFFERENTIATION FACTOR 88; PHOSPHATASE; TOLL LIKE RECEPTOR 5; TRAF INTERACTING FORKHEAD ASSOCIATED PROTEIN A; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; PHOSPHATE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; T2BP PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL FRACTIONATION; CELL PROLIFERATION; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; INTRACELLULAR BACTERIUM; LUCIFERASE ASSAY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SHIGELLA; SIGNAL TRANSDUCTION; CYTOSOL; GROWTH, DEVELOPMENT AND AGING; HELA CELL LINE; INTRACELLULAR SPACE; METABOLISM; MICROBIOLOGY; SHIGELLA FLEXNERI;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CYTOSOL; HELA CELLS; HUMANS; IMMUNITY, INNATE; INTRACELLULAR SPACE; NOD1 SIGNALING ADAPTOR PROTEIN; PHOSPHATES; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; VACUOLES;

EID: 85019231933     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.04.063     Document Type: Article

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