Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 25, 2013, Pages 10234-10239

  Malott, Rebecca J ^a,b   Keller, Bernd O ^c   Gaudet, Ryan G ^a   McCaw, Shannon E ^a   Lai, Christine C L ^a   Dobson Belaire, Wendy N ^a   Hobbs, J Leigh ^b   Michael, Frank ST ^d   Cox, Andrew D ^d   Moraes, Trevor F ^a   Gray Owen, Scott D ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b Department of Pediatrics   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Coinfection; Inflammation; Microbial associated molecular pattern; Pathogen associated molecular pattern; Sexually transmitted disease

Indexed keywords

HEPTOSE; HEPTOSE MONOPHOSPHATE; HLDA PROTEIN; LIPID A; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; HUMAN IMMUNODEFICIENCY VIRUS 1; INNATE IMMUNITY; MOUSE; MUTAGENESIS; NEISSERIA GONORRHOEAE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSPOSON;

COINFECTION; INFLAMMATION; MICROBIAL-ASSOCIATED MOLECULAR PATTERN; PATHOGEN-ASSOCIATED MOLECULAR PATTERN; SEXUALLY TRANSMITTED DISEASE;

BACTERIAL PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; COINFECTION; FEMALE; GONORRHEA; HEPTOSES; HIV INFECTIONS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; JURKAT CELLS; MALE; NEISSERIA GONORRHOEAE; TOLL-LIKE RECEPTOR 5;

HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; NEGIBACTERIA; NEISSERIA GONORRHOEAE;

EID: 84879295060     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1303738110     Document Type: Article

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