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Volumn 77, Issue 9, 2017, Pages 2464-2475

High-throughput genomic profiling of adult solid tumors reveals novel insights into cancer pathogenesis

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; NOTCH1 RECEPTOR; PHOSPHOTRANSFERASE; SMAD4 PROTEIN; TUMOR PROTEIN;

EID: 85019027650     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-2479     Document Type: Article
Times cited : (100)

References (51)
  • 1
    • 84877028141 scopus 로고    scopus 로고
    • Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
    • (2012) Nature , vol.490 , pp. 61-70
  • 2
    • 84907270779 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of gastric adenocarcinoma
    • The Cancer Genome Atlas Research Network
    • The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014;513:202-9.
    • (2014) Nature , vol.513 , pp. 202-209
  • 3
    • 84932628860 scopus 로고    scopus 로고
    • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
    • The Cancer Genome Atlas Research Network
    • The Cancer Genome Atlas Research Network. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 2015; 372:2481-98.
    • (2015) N Engl J Med , vol.372 , pp. 2481-2498
  • 4
    • 84923375535 scopus 로고    scopus 로고
    • Open access data sharing in genomic research
    • Pereira S, Gibbs RA, McGuire AL. Open access data sharing in genomic research. Genes 2014;5:739-47.
    • (2014) Genes , vol.5 , pp. 739-747
    • Pereira, S.1    Gibbs, R.A.2    McGuire, A.L.3
  • 6
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Verhaak RGW, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010;17:98-110.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.W.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6
  • 8
    • 84928761118 scopus 로고    scopus 로고
    • Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer
    • Rizvi NA, Hellmann MD, Snyder A, Kvistborg P,Makarov V, Havel JJ, et al. Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer. Science 2015;348:124-8.
    • (2015) Science , vol.348 , pp. 124-128
    • Rizvi, N.A.1    Hellmann, M.D.2    Snyder, A.3    Kvistborg, P.4    Makarov, V.5    Havel, J.J.6
  • 9
    • 84928582479 scopus 로고    scopus 로고
    • Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity
    • Catenacci DVT. Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity. Mol Oncol 2015;9: 967-96.
    • (2015) Mol Oncol , vol.9 , pp. 967-996
    • Catenacci, D.V.T.1
  • 10
    • 84900829967 scopus 로고    scopus 로고
    • Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
    • Kris MG, Johnson BE, Berry LD, Kwiatkowski DJ, Iafrate AJ,Wistuba II, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014;311:1998-2006.
    • (2014) JAMA , vol.311 , pp. 1998-2006
    • Kris, M.G.1    Johnson, B.E.2    Berry, L.D.3    Kwiatkowski, D.J.4    Iafrate, A.J.5    Wistuba, I.I.6
  • 11
    • 84887491073 scopus 로고    scopus 로고
    • Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
    • Frampton GM, Fichtenholtz A, Otto GA, Wang K, Downing SR, He J, et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol 2013;31: 1023-31.
    • (2013) Nat Biotechnol , vol.31 , pp. 1023-1031
    • Frampton, G.M.1    Fichtenholtz, A.2    Otto, G.A.3    Wang, K.4    Downing, S.R.5    He, J.6
  • 12
    • 80053189298 scopus 로고    scopus 로고
    • Predicting the functional impact of protein mutations: Application to cancer genomics
    • Reva B, Antipin Y, Sander C. Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res 2011;39: e118.
    • (2011) Nucleic Acids Res , vol.39 , pp. e118
    • Reva, B.1    Antipin, Y.2    Sander, C.3
  • 14
    • 84863922124 scopus 로고    scopus 로고
    • Comprehensive molecular characterization of human colon and rectal cancer
    • The Cancer Genome Atlas Network
    • The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487: 330-7.
    • (2012) Nature , vol.487 , pp. 330-337
  • 15
    • 84957550528 scopus 로고    scopus 로고
    • Identifying recurrentmutations in cancer reveals widespread lineage diversity and mutational specificity
    • Chang MT, Asthana S, Gao SP, Lee BH, Chapman JS, Kandoth C, et al. Identifying recurrentmutations in cancer reveals widespread lineage diversity and mutational specificity. Nat Biotechnol 2016;34:155-63.
    • (2016) Nat Biotechnol , vol.34 , pp. 155-163
    • Chang, M.T.1    Asthana, S.2    Gao, S.P.3    Lee, B.H.4    Chapman, J.S.5    Kandoth, C.6
  • 21
    • 84892986222 scopus 로고    scopus 로고
    • Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies
    • Ross JS, Wang K, Rand JV, Sheehan CE, Jennings TA, Al-Rohil RN, et al. Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. Am J Surg Pathol 2014;38:235-8.
    • (2014) Am J Surg Pathol , vol.38 , pp. 235-238
    • Ross, J.S.1    Wang, K.2    Rand, J.V.3    Sheehan, C.E.4    Jennings, T.A.5    Al-Rohil, R.N.6
  • 23
    • 84888246901 scopus 로고    scopus 로고
    • BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders
    • Damm F, Chesnais V, Nagata Y, Yoshida K, Scourzic L, Okuno Y, et al. BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders. Blood 2013;122:3169-77.
    • (2013) Blood , vol.122 , pp. 3169-3177
    • Damm, F.1    Chesnais, V.2    Nagata, Y.3    Yoshida, K.4    Scourzic, L.5    Okuno, Y.6
  • 24
    • 84896691170 scopus 로고    scopus 로고
    • Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors
    • Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, et al. Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. Cancer Discov 2014;4:216-31.
    • (2014) Cancer Discov , vol.4 , pp. 216-231
    • Shern, J.F.1    Chen, L.2    Chmielecki, J.3    Wei, J.S.4    Patidar, R.5    Rosenberg, M.6
  • 25
    • 0034879895 scopus 로고    scopus 로고
    • Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor
    • Bridge JA, KanamoriM,Ma Z, Pickering D, Hill DA, LydiattW, et al. Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. Am J Pathol 2001;159:411-5.
    • (2001) Am J Pathol , vol.159 , pp. 411-415
    • Bridge, J.A.1    Kanamori, M.2    Ma, Z.3    Pickering, D.4    Hill, D.A.5    Lydiatt, W.6
  • 26
    • 84896531092 scopus 로고    scopus 로고
    • Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer
    • Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, et al. Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. Proc Natl Acad Sci U S A 2014;111:4233-8.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 4233-4238
    • Kelly, L.M.1    Barila, G.2    Liu, P.3    Evdokimova, V.N.4    Trivedi, S.5    Panebianco, F.6
  • 27
    • 0033331028 scopus 로고    scopus 로고
    • High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: A strong correlation between RET/PTC3 and the solid-follicular variant
    • Thomas GA, Bunnell H, Cook HA, Williams ED, Nerovnya A, Cherstvoy ED, et al. High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant. J Clin Endocrinol Metab 1999;84:4232-8.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4232-4238
    • Thomas, G.A.1    Bunnell, H.2    Cook, H.A.3    Williams, E.D.4    Nerovnya, A.5    Cherstvoy, E.D.6
  • 28
    • 84969533090 scopus 로고    scopus 로고
    • Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer
    • FalchookGS,OrdonezNG,BastidaCC,StephensPJ, MillerVA,GaidoL,et al. Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer. J Clin Oncol 2016;34:e141-4.
    • (2016) J Clin Oncol , vol.34 , pp. e141-e144
    • Falchook, G.S.1    Ordonez, N.G.2    Bastida, C.C.3    Stephens, P.J.4    Miller, V.A.5    Gaido, L.6
  • 29
    • 84954362494 scopus 로고    scopus 로고
    • The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
    • Ross JS, Wang K, Chmielecki J, Gay L, Johnson A, Chudnovsky J, et al. The distribution of BRAF gene fusions in solid tumors and response to targeted therapy. Int J Cancer 2016;138:881-90.
    • (2016) Int J Cancer , vol.138 , pp. 881-890
    • Ross, J.S.1    Wang, K.2    Chmielecki, J.3    Gay, L.4    Johnson, A.5    Chudnovsky, J.6
  • 31
    • 84929501704 scopus 로고    scopus 로고
    • Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling
    • Ou SH, Chalmers ZR, Azada MC, Ross JS, Stephens PJ, Ali SM, et al. Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling. Lung Cancer 2015; 88:352-4.
    • (2015) Lung Cancer , vol.88 , pp. 352-354
    • Ou, S.H.1    Chalmers, Z.R.2    Azada, M.C.3    Ross, J.S.4    Stephens, P.J.5    Ali, S.M.6
  • 32
    • 0037402509 scopus 로고    scopus 로고
    • Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
    • Charest A, Lane K, McMahon K, Park J, Preisinger E, Conroy H, et al. Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21). Genes Chromosom Cancer 2003;37:58-71.
    • (2003) Genes Chromosom Cancer , vol.37 , pp. 58-71
    • Charest, A.1    Lane, K.2    McMahon, K.3    Park, J.4    Preisinger, E.5    Conroy, H.6
  • 33
    • 84871181092 scopus 로고    scopus 로고
    • Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions
    • Suehara Y, Arcila M, Wang L, Hasanovic A, Ang D, Ito T, et al. Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions. Clin Cancer Res 2012;18:6599-608.
    • (2012) Clin Cancer Res , vol.18 , pp. 6599-6608
    • Suehara, Y.1    Arcila, M.2    Wang, L.3    Hasanovic, A.4    Ang, D.5    Ito, T.6
  • 35
    • 1842474941 scopus 로고    scopus 로고
    • The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: Implications for diagnosis, classification, and management
    • Gotlib J, Cools J, Malone JM, Schrier SL, Gilliland DG, Coutré SE. The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management. Blood 2004;103:2879-91.
    • (2004) Blood , vol.103 , pp. 2879-2891
    • Gotlib, J.1    Cools, J.2    Malone, J.M.3    Schrier, S.L.4    Gilliland, D.G.5    Coutré, S.E.6
  • 36
    • 84921279242 scopus 로고    scopus 로고
    • Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin
    • Chmielecki J, Ross JS, Wang K, Frampton GM, Palmer GA, Ali SM, et al. Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin. Oncologist 2015;20:7-12.
    • (2015) Oncologist , vol.20 , pp. 7-12
    • Chmielecki, J.1    Ross, J.S.2    Wang, K.3    Frampton, G.M.4    Palmer, G.A.5    Ali, S.M.6
  • 37
    • 84975256001 scopus 로고    scopus 로고
    • Comprehensive genomic profiling identifies frequent drug-sensitive EGFR exon 19 deletions in NSCLC not identified by prior molecular testing
    • Schrock AB, Frampton GM, Herndon D, Greenbowe JR, Wang K, Lipson D, et al. Comprehensive genomic profiling identifies frequent drug-sensitive EGFR exon 19 deletions in NSCLC not identified by prior molecular testing. Clin Cancer Res 2016;22:3281-5.
    • (2016) Clin Cancer Res , vol.22 , pp. 3281-3285
    • Schrock, A.B.1    Frampton, G.M.2    Herndon, D.3    Greenbowe, J.R.4    Wang, K.5    Lipson, D.6
  • 38
    • 84954401021 scopus 로고    scopus 로고
    • Systematic discovery of complex insertions and deletions in human cancers
    • Ye K, Wang J, Jayasinghe R, Lameijer EW, McMichael JF, Ning J, et al. Systematic discovery of complex insertions and deletions in human cancers. Nat Med 2016;22:97-104.
    • (2016) Nat Med , vol.22 , pp. 97-104
    • Ye, K.1    Wang, J.2    Jayasinghe, R.3    Lameijer, E.W.4    McMichael, J.F.5    Ning, J.6
  • 39
    • 84954202031 scopus 로고    scopus 로고
    • Extended RAS gene mutation testing in metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015
    • Allegra CJ, Rumble RB, Hamilton SR, Mangu PB, Roach N, Hantel A, et al. Extended RAS gene mutation testing in metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015. J Clin Oncol 2016;34:179-85.
    • (2016) J Clin Oncol , vol.34 , pp. 179-185
    • Allegra, C.J.1    Rumble, R.B.2    Hamilton, S.R.3    Mangu, P.B.4    Roach, N.5    Hantel, A.6
  • 40
    • 0034735995 scopus 로고    scopus 로고
    • A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma
    • Tsukuda K, Tanino M, Soga H, Shimizu N, Shimizu K. A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma. Biochem Biophys Res Commun 2000;278:653-8.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 653-658
    • Tsukuda, K.1    Tanino, M.2    Soga, H.3    Shimizu, N.4    Shimizu, K.5
  • 41
    • 78650472338 scopus 로고    scopus 로고
    • Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders
    • Gremer L,Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, ZenkerM, et al. Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat 2011;32: 33-43.
    • (2011) Hum Mutat , vol.32 , pp. 33-43
    • Gremer, L.1    Merbitz-Zahradnik, T.2    Dvorsky, R.3    Cirstea, I.C.4    Kratz, C.P.5    Zenker, M.6
  • 42
    • 84883179862 scopus 로고    scopus 로고
    • Targeting the ERBB family in cancer: Couples therapy
    • Tebbutt N, Pedersen MW, Johns TG. Targeting the ERBB family in cancer: couples therapy. Nat Rev Cancer 2013;13:663-73.
    • (2013) Nat Rev Cancer , vol.13 , pp. 663-673
    • Tebbutt, N.1    Pedersen, M.W.2    Johns, T.G.3
  • 44
    • 84880695940 scopus 로고    scopus 로고
    • Phase II Trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma
    • Dickson MA, Tap WD, Keohan ML, D'Angelo SP, Gounder MM, Antonescu CR, et al. Phase II Trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma. J Clin Oncol 2013;31:2024-8.
    • (2013) J Clin Oncol , vol.31 , pp. 2024-2028
    • Dickson, M.A.1    Tap, W.D.2    Keohan, M.L.3    D'Angelo, S.P.4    Gounder, M.M.5    Antonescu, C.R.6
  • 45
    • 84905699926 scopus 로고    scopus 로고
    • Palbociclib: An evidence-based review of its potential in the treatment of breast cancer
    • Cadoo KA, Gucalp A, Traina TA. Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. Breast Cancer 2014;6: 123-33.
    • (2014) Breast Cancer , vol.6 , pp. 123-133
    • Cadoo, K.A.1    Gucalp, A.2    Traina, T.A.3
  • 46
    • 80053376506 scopus 로고    scopus 로고
    • Cyclin D1 and Cdk4 mediate development of neurologically destructive oligodendroglioma
    • Ciznadija D, Liu Y, Pyonteck SM, Holland EC, Koff A. Cyclin D1 and Cdk4 mediate development of neurologically destructive oligodendroglioma. Cancer Res 2011;71:6174-83.
    • (2011) Cancer Res , vol.71 , pp. 6174-6183
    • Ciznadija, D.1    Liu, Y.2    Pyonteck, S.M.3    Holland, E.C.4    Koff, A.5
  • 47
    • 84862908734 scopus 로고    scopus 로고
    • Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastomawith amesenchymal-epithelial transition inhibitor
    • Chi AS, Batchelor TT, Kwak EL, Clark JW, Wang DL, Wilner KD, et al. Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastomawith amesenchymal-epithelial transition inhibitor. J Clin Oncol 2012;30:e30-3.
    • (2012) J Clin Oncol , vol.30 , pp. e30-e33
    • Chi, A.S.1    Batchelor, T.T.2    Kwak, E.L.3    Clark, J.W.4    Wang, D.L.5    Wilner, K.D.6
  • 48
    • 43249115083 scopus 로고    scopus 로고
    • Mutational analysis of oncogenic AKT E17Kmutation incommon solid cancers and acute leukaemias
    • Kim MS, Jeong EG, Yoo NJ, Lee SH. Mutational analysis of oncogenic AKT E17Kmutation incommon solid cancers and acute leukaemias. Br J Cancer 2008;98:1533-5.
    • (2008) Br J Cancer , vol.98 , pp. 1533-1535
    • Kim, M.S.1    Jeong, E.G.2    Yoo, N.J.3    Lee, S.H.4
  • 49
    • 84957927905 scopus 로고    scopus 로고
    • Less frequently mutated genes in colorectal cancer: Evidences from next-generation sequencing of 653 routine cases
    • Malapelle U, Pisapia P, Sgariglia R, Vigliar E, Biglietto M, Carlomagno C, et al. Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases. J Clin Pathol 2016; 69:767-71.
    • (2016) J Clin Pathol , vol.69 , pp. 767-771
    • Malapelle, U.1    Pisapia, P.2    Sgariglia, R.3    Vigliar, E.4    Biglietto, M.5    Carlomagno, C.6
  • 50
    • 84942306431 scopus 로고    scopus 로고
    • AKT1 E17K in colorectal carcinoma is associated with BRAF V600E but not MSI-H status: A clinicopathologic comparison to PIK3CA helical and kinase domain mutants
    • Hechtman JF, Sadowska J, Huse JT, Borsu L, Yaeger R, Shia J, et al. AKT1 E17K in colorectal carcinoma is associated with BRAF V600E but not MSI-H status: a clinicopathologic comparison to PIK3CA helical and kinase domain mutants. Mol Cancer Res 2015;13:1003-8.
    • (2015) Mol Cancer Res , vol.13 , pp. 1003-1008
    • Hechtman, J.F.1    Sadowska, J.2    Huse, J.T.3    Borsu, L.4    Yaeger, R.5    Shia, J.6
  • 51
    • 84903547236 scopus 로고    scopus 로고
    • Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
    • Ledermann J, Harter P, Gourley C, FriedlanderM, Vergote I, Rustin G, et al. Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol 2014;15:852-61.
    • (2014) Lancet Oncol , vol.15 , pp. 852-861
    • Ledermann, J.1    Harter, P.2    Gourley, C.3    Friedlander, M.4    Vergote, I.5    Rustin, G.6


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