-
1
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature 2012;490:61-70.
-
(2012)
Nature
, vol.490
, pp. 61-70
-
-
-
2
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014;513:202-9.
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
3
-
-
84932628860
-
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 2015; 372:2481-98.
-
(2015)
N Engl J Med
, vol.372
, pp. 2481-2498
-
-
-
4
-
-
84923375535
-
Open access data sharing in genomic research
-
Pereira S, Gibbs RA, McGuire AL. Open access data sharing in genomic research. Genes 2014;5:739-47.
-
(2014)
Genes
, vol.5
, pp. 739-747
-
-
Pereira, S.1
Gibbs, R.A.2
McGuire, A.L.3
-
5
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RGW, McKenna A, Campos B, Noushmehr H, Salama SR, et al. The somatic genomic landscape of glioblastoma. Cell 2013;155:462-77.
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.W.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
Salama, S.R.6
-
6
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RGW, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010;17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.W.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
-
7
-
-
85019046561
-
-
FortWashington, PA: National Comprehensive Cancer Network [cited 2016 Nov 21]
-
Ettinger DS,WoodDE, Chair Fred V, Aisner DL, Bauman J, Chirieac LR, et al. NCCN Guidelines Version 3.2017 Panel Members Non-Small Cell Lung Cancer-Farber/Brigham and Women'sCancer Center. FortWashington, PA: National Comprehensive Cancer Network; 2016[cited 2016 Nov 21]. Available from: https://www.nccn.org/professionals/physician-gls/pdf/nscl.pdf.
-
(2016)
NCCN Guidelines Version 3.2017 Panel Members Non-small Cell Lung Cancer-farber/Brigham and Women'scancer Center
-
-
Ettinger, D.S.1
Wood, D.E.2
Chair Fred, V.3
Aisner, D.L.4
Bauman, J.5
Chirieac, L.R.6
-
8
-
-
84928761118
-
Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P,Makarov V, Havel JJ, et al. Mutational landscape determines sensitivity to PD-1 blockade in nonsmall cell lung cancer. Science 2015;348:124-8.
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
-
9
-
-
84928582479
-
Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity
-
Catenacci DVT. Next-generation clinical trials: Novel strategies to address the challenge of tumor molecular heterogeneity. Mol Oncol 2015;9: 967-96.
-
(2015)
Mol Oncol
, vol.9
, pp. 967-996
-
-
Catenacci, D.V.T.1
-
10
-
-
84900829967
-
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs
-
Kris MG, Johnson BE, Berry LD, Kwiatkowski DJ, Iafrate AJ,Wistuba II, et al. Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs. JAMA 2014;311:1998-2006.
-
(2014)
JAMA
, vol.311
, pp. 1998-2006
-
-
Kris, M.G.1
Johnson, B.E.2
Berry, L.D.3
Kwiatkowski, D.J.4
Iafrate, A.J.5
Wistuba, I.I.6
-
11
-
-
84887491073
-
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
-
Frampton GM, Fichtenholtz A, Otto GA, Wang K, Downing SR, He J, et al. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing. Nat Biotechnol 2013;31: 1023-31.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1023-1031
-
-
Frampton, G.M.1
Fichtenholtz, A.2
Otto, G.A.3
Wang, K.4
Downing, S.R.5
He, J.6
-
12
-
-
80053189298
-
Predicting the functional impact of protein mutations: Application to cancer genomics
-
Reva B, Antipin Y, Sander C. Predicting the functional impact of protein mutations: application to cancer genomics. Nucleic Acids Res 2011;39: e118.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. e118
-
-
Reva, B.1
Antipin, Y.2
Sander, C.3
-
13
-
-
77951640946
-
A method and server for predicting damaging missense mutations
-
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, et al. A method and server for predicting damaging missense mutations. Nat Methods 2010;7:248-9.
-
(2010)
Nat Methods
, vol.7
, pp. 248-249
-
-
Adzhubei, I.A.1
Schmidt, S.2
Peshkin, L.3
Ramensky, V.E.4
Gerasimova, A.5
Bork, P.6
-
14
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
The Cancer Genome Atlas Network
-
The Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487: 330-7.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
15
-
-
84957550528
-
Identifying recurrentmutations in cancer reveals widespread lineage diversity and mutational specificity
-
Chang MT, Asthana S, Gao SP, Lee BH, Chapman JS, Kandoth C, et al. Identifying recurrentmutations in cancer reveals widespread lineage diversity and mutational specificity. Nat Biotechnol 2016;34:155-63.
-
(2016)
Nat Biotechnol
, vol.34
, pp. 155-163
-
-
Chang, M.T.1
Asthana, S.2
Gao, S.P.3
Lee, B.H.4
Chapman, J.S.5
Kandoth, C.6
-
16
-
-
84872510974
-
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
-
Fleming NI, Jorissen RN, Mouradov D, ChristieM, Sakthianandeswaren A, Palmieri M, et al. SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res 2013;73:725-35.
-
(2013)
Cancer Res
, vol.73
, pp. 725-735
-
-
Fleming, N.I.1
Jorissen, R.N.2
Mouradov, D.3
Christie, M.4
Sakthianandeswaren, A.5
Palmieri, M.6
-
17
-
-
85019015242
-
The molecular landscape of recurrent and metastatic head and neck cancers
-
Jul 21. [Epub ahead of print]
-
Morris LGT, Chandramohan R, West L, Zehir A, Chakravarty D, Pfister DG, et al. The molecular landscape of recurrent and metastatic head and neck cancers. JAMA Oncol. 2016 Jul 21. [Epub ahead of print].
-
(2016)
JAMA Oncol.
-
-
Morris, L.G.T.1
Chandramohan, R.2
West, L.3
Zehir, A.4
Chakravarty, D.5
Pfister, D.G.6
-
18
-
-
5044225888
-
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
-
Weng AP, Ferrando AA, Lee W, Morris JP, Silverman LB, Sanchez-Irizarry C, et al. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 2004;306:269-71.
-
(2004)
Science
, vol.306
, pp. 269-271
-
-
Weng, A.P.1
Ferrando, A.A.2
Lee, W.3
Morris, J.P.4
Silverman, L.B.5
Sanchez-Irizarry, C.6
-
19
-
-
84879689007
-
The mutational landscape of adenoid cystic carcinoma
-
Ho AS, Kannan K, Roy DM, Morris LGT, Ganly I, Katabi N, et al. The mutational landscape of adenoid cystic carcinoma. Nat Genet 2013;45:791-8.
-
(2013)
Nat Genet
, vol.45
, pp. 791-798
-
-
Ho, A.S.1
Kannan, K.2
Roy, D.M.3
Morris, L.G.T.4
Ganly, I.5
Katabi, N.6
-
20
-
-
84879627051
-
Whole exome sequencing of adenoid cystic carcinoma
-
Stephens PJ, Davies HR, Mitani Y, Van Loo P, Shlien A, Tarpey PS, et al. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest 2013;123:2965-8.
-
(2013)
J Clin Invest
, vol.123
, pp. 2965-2968
-
-
Stephens, P.J.1
Davies, H.R.2
Mitani, Y.3
Van Loo, P.4
Shlien, A.5
Tarpey, P.S.6
-
21
-
-
84892986222
-
Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies
-
Ross JS, Wang K, Rand JV, Sheehan CE, Jennings TA, Al-Rohil RN, et al. Comprehensive genomic profiling of relapsed and metastatic adenoid cystic carcinomas by next-generation sequencing reveals potential new routes to targeted therapies. Am J Surg Pathol 2014;38:235-8.
-
(2014)
Am J Surg Pathol
, vol.38
, pp. 235-238
-
-
Ross, J.S.1
Wang, K.2
Rand, J.V.3
Sheehan, C.E.4
Jennings, T.A.5
Al-Rohil, R.N.6
-
23
-
-
84888246901
-
BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders
-
Damm F, Chesnais V, Nagata Y, Yoshida K, Scourzic L, Okuno Y, et al. BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders. Blood 2013;122:3169-77.
-
(2013)
Blood
, vol.122
, pp. 3169-3177
-
-
Damm, F.1
Chesnais, V.2
Nagata, Y.3
Yoshida, K.4
Scourzic, L.5
Okuno, Y.6
-
24
-
-
84896691170
-
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors
-
Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, et al. Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors. Cancer Discov 2014;4:216-31.
-
(2014)
Cancer Discov
, vol.4
, pp. 216-231
-
-
Shern, J.F.1
Chen, L.2
Chmielecki, J.3
Wei, J.S.4
Patidar, R.5
Rosenberg, M.6
-
25
-
-
0034879895
-
Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor
-
Bridge JA, KanamoriM,Ma Z, Pickering D, Hill DA, LydiattW, et al. Fusion of the ALK gene to the clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. Am J Pathol 2001;159:411-5.
-
(2001)
Am J Pathol
, vol.159
, pp. 411-415
-
-
Bridge, J.A.1
Kanamori, M.2
Ma, Z.3
Pickering, D.4
Hill, D.A.5
Lydiatt, W.6
-
26
-
-
84896531092
-
Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer
-
Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, et al. Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. Proc Natl Acad Sci U S A 2014;111:4233-8.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 4233-4238
-
-
Kelly, L.M.1
Barila, G.2
Liu, P.3
Evdokimova, V.N.4
Trivedi, S.5
Panebianco, F.6
-
27
-
-
0033331028
-
High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: A strong correlation between RET/PTC3 and the solid-follicular variant
-
Thomas GA, Bunnell H, Cook HA, Williams ED, Nerovnya A, Cherstvoy ED, et al. High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant. J Clin Endocrinol Metab 1999;84:4232-8.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 4232-4238
-
-
Thomas, G.A.1
Bunnell, H.2
Cook, H.A.3
Williams, E.D.4
Nerovnya, A.5
Cherstvoy, E.D.6
-
28
-
-
84969533090
-
Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer
-
FalchookGS,OrdonezNG,BastidaCC,StephensPJ, MillerVA,GaidoL,et al. Effect of the RET inhibitor vandetanib in a patient with RET fusion-positive metastatic non-small-cell lung cancer. J Clin Oncol 2016;34:e141-4.
-
(2016)
J Clin Oncol
, vol.34
, pp. e141-e144
-
-
Falchook, G.S.1
Ordonez, N.G.2
Bastida, C.C.3
Stephens, P.J.4
Miller, V.A.5
Gaido, L.6
-
29
-
-
84954362494
-
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
-
Ross JS, Wang K, Chmielecki J, Gay L, Johnson A, Chudnovsky J, et al. The distribution of BRAF gene fusions in solid tumors and response to targeted therapy. Int J Cancer 2016;138:881-90.
-
(2016)
Int J Cancer
, vol.138
, pp. 881-890
-
-
Ross, J.S.1
Wang, K.2
Chmielecki, J.3
Gay, L.4
Johnson, A.5
Chudnovsky, J.6
-
30
-
-
84886292349
-
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy
-
Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, et al. Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy. Pigment Cell Melanoma Res 2013;26:845-51.
-
(2013)
Pigment Cell Melanoma Res
, vol.26
, pp. 845-851
-
-
Botton, T.1
Yeh, I.2
Nelson, T.3
Vemula, S.S.4
Sparatta, A.5
Garrido, M.C.6
-
31
-
-
84929501704
-
Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling
-
Ou SH, Chalmers ZR, Azada MC, Ross JS, Stephens PJ, Ali SM, et al. Identification of a novel TMEM106B-ROS1 fusion variant in lung adenocarcinoma by comprehensive genomic profiling. Lung Cancer 2015; 88:352-4.
-
(2015)
Lung Cancer
, vol.88
, pp. 352-354
-
-
Ou, S.H.1
Chalmers, Z.R.2
Azada, M.C.3
Ross, J.S.4
Stephens, P.J.5
Ali, S.M.6
-
32
-
-
0037402509
-
Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21)
-
Charest A, Lane K, McMahon K, Park J, Preisinger E, Conroy H, et al. Fusion of FIG to the receptor tyrosine kinase ROS in a glioblastoma with an interstitial del(6)(q21q21). Genes Chromosom Cancer 2003;37:58-71.
-
(2003)
Genes Chromosom Cancer
, vol.37
, pp. 58-71
-
-
Charest, A.1
Lane, K.2
McMahon, K.3
Park, J.4
Preisinger, E.5
Conroy, H.6
-
33
-
-
84871181092
-
Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions
-
Suehara Y, Arcila M, Wang L, Hasanovic A, Ang D, Ito T, et al. Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions. Clin Cancer Res 2012;18:6599-608.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6599-6608
-
-
Suehara, Y.1
Arcila, M.2
Wang, L.3
Hasanovic, A.4
Ang, D.5
Ito, T.6
-
34
-
-
84907948624
-
Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR
-
Peraldo Neia C, Cavalloni G, Balsamo A, Venesio T, Napoli F, Sassi F, et al. Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR. Genes Chromosomes Cancer 2014;53:1033-40.
-
(2014)
Genes Chromosomes Cancer
, vol.53
, pp. 1033-1040
-
-
Peraldo Neia, C.1
Cavalloni, G.2
Balsamo, A.3
Venesio, T.4
Napoli, F.5
Sassi, F.6
-
35
-
-
1842474941
-
The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: Implications for diagnosis, classification, and management
-
Gotlib J, Cools J, Malone JM, Schrier SL, Gilliland DG, Coutré SE. The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management. Blood 2004;103:2879-91.
-
(2004)
Blood
, vol.103
, pp. 2879-2891
-
-
Gotlib, J.1
Cools, J.2
Malone, J.M.3
Schrier, S.L.4
Gilliland, D.G.5
Coutré, S.E.6
-
36
-
-
84921279242
-
Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin
-
Chmielecki J, Ross JS, Wang K, Frampton GM, Palmer GA, Ali SM, et al. Oncogenic alterations in ERBB2/HER2 represent potential therapeutic targets across tumors from diverse anatomic sites of origin. Oncologist 2015;20:7-12.
-
(2015)
Oncologist
, vol.20
, pp. 7-12
-
-
Chmielecki, J.1
Ross, J.S.2
Wang, K.3
Frampton, G.M.4
Palmer, G.A.5
Ali, S.M.6
-
37
-
-
84975256001
-
Comprehensive genomic profiling identifies frequent drug-sensitive EGFR exon 19 deletions in NSCLC not identified by prior molecular testing
-
Schrock AB, Frampton GM, Herndon D, Greenbowe JR, Wang K, Lipson D, et al. Comprehensive genomic profiling identifies frequent drug-sensitive EGFR exon 19 deletions in NSCLC not identified by prior molecular testing. Clin Cancer Res 2016;22:3281-5.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 3281-3285
-
-
Schrock, A.B.1
Frampton, G.M.2
Herndon, D.3
Greenbowe, J.R.4
Wang, K.5
Lipson, D.6
-
38
-
-
84954401021
-
Systematic discovery of complex insertions and deletions in human cancers
-
Ye K, Wang J, Jayasinghe R, Lameijer EW, McMichael JF, Ning J, et al. Systematic discovery of complex insertions and deletions in human cancers. Nat Med 2016;22:97-104.
-
(2016)
Nat Med
, vol.22
, pp. 97-104
-
-
Ye, K.1
Wang, J.2
Jayasinghe, R.3
Lameijer, E.W.4
McMichael, J.F.5
Ning, J.6
-
39
-
-
84954202031
-
Extended RAS gene mutation testing in metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015
-
Allegra CJ, Rumble RB, Hamilton SR, Mangu PB, Roach N, Hantel A, et al. Extended RAS gene mutation testing in metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015. J Clin Oncol 2016;34:179-85.
-
(2016)
J Clin Oncol
, vol.34
, pp. 179-185
-
-
Allegra, C.J.1
Rumble, R.B.2
Hamilton, S.R.3
Mangu, P.B.4
Roach, N.5
Hantel, A.6
-
40
-
-
0034735995
-
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma
-
Tsukuda K, Tanino M, Soga H, Shimizu N, Shimizu K. A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma. Biochem Biophys Res Commun 2000;278:653-8.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 653-658
-
-
Tsukuda, K.1
Tanino, M.2
Soga, H.3
Shimizu, N.4
Shimizu, K.5
-
41
-
-
78650472338
-
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders
-
Gremer L,Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, ZenkerM, et al. Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders. Hum Mutat 2011;32: 33-43.
-
(2011)
Hum Mutat
, vol.32
, pp. 33-43
-
-
Gremer, L.1
Merbitz-Zahradnik, T.2
Dvorsky, R.3
Cirstea, I.C.4
Kratz, C.P.5
Zenker, M.6
-
42
-
-
84883179862
-
Targeting the ERBB family in cancer: Couples therapy
-
Tebbutt N, Pedersen MW, Johns TG. Targeting the ERBB family in cancer: couples therapy. Nat Rev Cancer 2013;13:663-73.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 663-673
-
-
Tebbutt, N.1
Pedersen, M.W.2
Johns, T.G.3
-
43
-
-
84894231823
-
Landscape of genomic alterations in cervical carcinomas
-
Ojesina AI, Lichtenstein L, Freeman SS, Pedamallu CS, Imaz-Rosshandler I, Pugh TJ, et al. Landscape of genomic alterations in cervical carcinomas. Nature 2014;506:371-5.
-
(2014)
Nature
, vol.506
, pp. 371-375
-
-
Ojesina, A.I.1
Lichtenstein, L.2
Freeman, S.S.3
Pedamallu, C.S.4
Imaz-Rosshandler, I.5
Pugh, T.J.6
-
44
-
-
84880695940
-
Phase II Trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma
-
Dickson MA, Tap WD, Keohan ML, D'Angelo SP, Gounder MM, Antonescu CR, et al. Phase II Trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma. J Clin Oncol 2013;31:2024-8.
-
(2013)
J Clin Oncol
, vol.31
, pp. 2024-2028
-
-
Dickson, M.A.1
Tap, W.D.2
Keohan, M.L.3
D'Angelo, S.P.4
Gounder, M.M.5
Antonescu, C.R.6
-
45
-
-
84905699926
-
Palbociclib: An evidence-based review of its potential in the treatment of breast cancer
-
Cadoo KA, Gucalp A, Traina TA. Palbociclib: an evidence-based review of its potential in the treatment of breast cancer. Breast Cancer 2014;6: 123-33.
-
(2014)
Breast Cancer
, vol.6
, pp. 123-133
-
-
Cadoo, K.A.1
Gucalp, A.2
Traina, T.A.3
-
46
-
-
80053376506
-
Cyclin D1 and Cdk4 mediate development of neurologically destructive oligodendroglioma
-
Ciznadija D, Liu Y, Pyonteck SM, Holland EC, Koff A. Cyclin D1 and Cdk4 mediate development of neurologically destructive oligodendroglioma. Cancer Res 2011;71:6174-83.
-
(2011)
Cancer Res
, vol.71
, pp. 6174-6183
-
-
Ciznadija, D.1
Liu, Y.2
Pyonteck, S.M.3
Holland, E.C.4
Koff, A.5
-
47
-
-
84862908734
-
Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastomawith amesenchymal-epithelial transition inhibitor
-
Chi AS, Batchelor TT, Kwak EL, Clark JW, Wang DL, Wilner KD, et al. Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastomawith amesenchymal-epithelial transition inhibitor. J Clin Oncol 2012;30:e30-3.
-
(2012)
J Clin Oncol
, vol.30
, pp. e30-e33
-
-
Chi, A.S.1
Batchelor, T.T.2
Kwak, E.L.3
Clark, J.W.4
Wang, D.L.5
Wilner, K.D.6
-
48
-
-
43249115083
-
Mutational analysis of oncogenic AKT E17Kmutation incommon solid cancers and acute leukaemias
-
Kim MS, Jeong EG, Yoo NJ, Lee SH. Mutational analysis of oncogenic AKT E17Kmutation incommon solid cancers and acute leukaemias. Br J Cancer 2008;98:1533-5.
-
(2008)
Br J Cancer
, vol.98
, pp. 1533-1535
-
-
Kim, M.S.1
Jeong, E.G.2
Yoo, N.J.3
Lee, S.H.4
-
49
-
-
84957927905
-
Less frequently mutated genes in colorectal cancer: Evidences from next-generation sequencing of 653 routine cases
-
Malapelle U, Pisapia P, Sgariglia R, Vigliar E, Biglietto M, Carlomagno C, et al. Less frequently mutated genes in colorectal cancer: evidences from next-generation sequencing of 653 routine cases. J Clin Pathol 2016; 69:767-71.
-
(2016)
J Clin Pathol
, vol.69
, pp. 767-771
-
-
Malapelle, U.1
Pisapia, P.2
Sgariglia, R.3
Vigliar, E.4
Biglietto, M.5
Carlomagno, C.6
-
50
-
-
84942306431
-
AKT1 E17K in colorectal carcinoma is associated with BRAF V600E but not MSI-H status: A clinicopathologic comparison to PIK3CA helical and kinase domain mutants
-
Hechtman JF, Sadowska J, Huse JT, Borsu L, Yaeger R, Shia J, et al. AKT1 E17K in colorectal carcinoma is associated with BRAF V600E but not MSI-H status: a clinicopathologic comparison to PIK3CA helical and kinase domain mutants. Mol Cancer Res 2015;13:1003-8.
-
(2015)
Mol Cancer Res
, vol.13
, pp. 1003-1008
-
-
Hechtman, J.F.1
Sadowska, J.2
Huse, J.T.3
Borsu, L.4
Yaeger, R.5
Shia, J.6
-
51
-
-
84903547236
-
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
-
Ledermann J, Harter P, Gourley C, FriedlanderM, Vergote I, Rustin G, et al. Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol 2014;15:852-61.
-
(2014)
Lancet Oncol
, vol.15
, pp. 852-861
-
-
Ledermann, J.1
Harter, P.2
Gourley, C.3
Friedlander, M.4
Vergote, I.5
Rustin, G.6
|