메뉴 건너뛰기




Volumn 5, Issue 1, 2017, Pages 67-78

Retinal Degeneration and Regeneration—Lessons From Fishes and Amphibians

Author keywords

Ciliary marginal zone; M ller glial cells; Retinal degeneration; Retinal pigment epithelium; Retinal regeneration; Retinal stem cells

Indexed keywords


EID: 85019022639     PISSN: None     EISSN: 2167485X     Source Type: Journal    
DOI: 10.1007/s40139-017-0127-9     Document Type: Review
Times cited : (35)

References (152)
  • 2
    • 10744230959 scopus 로고    scopus 로고
    • In utero gene therapy rescues vision in a murine model of congenital blindness
    • COI: 1:CAS:528:DC%2BD2cXptVWrtA%3D%3D, PID: 14759802
    • Dejneka NS, Surace EM, Aleman TS, Cideciyan AV, Lyubarsky A, Savchenko A et al (2004) In utero gene therapy rescues vision in a murine model of congenital blindness. Mol Ther 9(2):182–188
    • (2004) Mol Ther , vol.9 , Issue.2 , pp. 182-188
    • Dejneka, N.S.1    Surace, E.M.2    Aleman, T.S.3    Cideciyan, A.V.4    Lyubarsky, A.5    Savchenko, A.6
  • 3
    • 84927571602 scopus 로고    scopus 로고
    • Retinitis pigmentosa overview
    • (,),. In:, Pagon, RA, Adam, MP, Ardinger, HH, Wallace, SE, Amemiya, A, Bean, LJH, Bird, TD, Ledbetter, N, Mefford, HC, Smith, RJH, Stephens, K, (eds),., University of Washington, Seattle
    • Fahim AT, Daiger SP, Weleber RG (2013) Retinitis pigmentosa overview. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Ledbetter N, Mefford HC, Smith RJH, Stephens K (eds) GeneReviews. University of Washington, Seattle
    • (2013) GeneReviews
    • Fahim, A.T.1    Daiger, S.P.2    Weleber, R.G.3
  • 5
    • 6344241300 scopus 로고    scopus 로고
    • The epidemiology of age-related macular degeneration
    • PID: 15577562
    • Seddon JM, Chen CA (2004) The epidemiology of age-related macular degeneration. Int Ophthalmol Clin 44(4):17–39
    • (2004) Int Ophthalmol Clin , vol.44 , Issue.4 , pp. 17-39
    • Seddon, J.M.1    Chen, C.A.2
  • 6
    • 84943658875 scopus 로고    scopus 로고
    • The genetics of age-related macular degeneration (AMD)—novel targets for designing treatment options?
    • COI: 1:CAS:528:DC%2BC2MXoslCksrY%3D, PID: 25986585
    • Grassmann F, Fauser S, Weber BH (2015) The genetics of age-related macular degeneration (AMD)—novel targets for designing treatment options? Eur J Pharm Biopharm 95(Pt B):194–202
    • (2015) Eur J Pharm Biopharm , vol.95 , pp. 194-202
    • Grassmann, F.1    Fauser, S.2    Weber, B.H.3
  • 7
    • 70349330817 scopus 로고    scopus 로고
    • VEGF Trap-Eye for the treatment of neovascular age-related macular degeneration
    • COI: 1:CAS:528:DC%2BD1MXhtFCisLbP, PID: 19694600
    • Dixon JA, Oliver SC, Olson JL, Mandava N (2009) VEGF Trap-Eye for the treatment of neovascular age-related macular degeneration. Expert Opin Investig Drugs 18(10):1573–1580
    • (2009) Expert Opin Investig Drugs , vol.18 , Issue.10 , pp. 1573-1580
    • Dixon, J.A.1    Oliver, S.C.2    Olson, J.L.3    Mandava, N.4
  • 8
    • 79958786721 scopus 로고    scopus 로고
    • A systematic review of the efficacy and safety outcomes of anti-VEGF agents used for treating neovascular age-related macular degeneration: comparison of ranibizumab and bevacizumab
    • COI: 1:CAS:528:DC%2BC3MXnsFOjsrc%3D, PID: 21623685
    • Mitchell P (2011) A systematic review of the efficacy and safety outcomes of anti-VEGF agents used for treating neovascular age-related macular degeneration: comparison of ranibizumab and bevacizumab. Curr Med Res Opin 27(7):1465–1475
    • (2011) Curr Med Res Opin , vol.27 , Issue.7 , pp. 1465-1475
    • Mitchell, P.1
  • 9
    • 84955419184 scopus 로고    scopus 로고
    • Lutein, zeaxanthin, and meso-zeaxanthin: the basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease
    • COI: 1:CAS:528:DC%2BC2MXhslOrs77P, PID: 26541886
    • Bernstein PS, Li B, Vachali PP, Gorusupudi A, Shyam R, Henriksen BS et al (2016) Lutein, zeaxanthin, and meso-zeaxanthin: the basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog Retin Eye Res 50:34–66
    • (2016) Prog Retin Eye Res , vol.50 , pp. 34-66
    • Bernstein, P.S.1    Li, B.2    Vachali, P.P.3    Gorusupudi, A.4    Shyam, R.5    Henriksen, B.S.6
  • 11
    • 84964467835 scopus 로고    scopus 로고
    • Photoreceptor transplantation in late stage retinal degeneration
    • Reh TA (2016) Photoreceptor transplantation in late stage retinal degeneration. Invest Ophthalmol Vis Sci 57:ORSFg1–ORSFg7
    • (2016) Invest Ophthalmol Vis Sci , vol.57 , pp. ORSFg1-ORSFg7
    • Reh, T.A.1
  • 12
    • 84859192198 scopus 로고    scopus 로고
    • Restoration of vision after transplantation of photoreceptors
    • COI: 1:CAS:528:DC%2BC38XmtVektLc%3D, PID: 22522934
    • Pearson RA, Barber AC, Rizzi M, Hippert C, Xue T, West EL et al (2012) Restoration of vision after transplantation of photoreceptors. Nature 485(7396):99–103
    • (2012) Nature , vol.485 , Issue.7396 , pp. 99-103
    • Pearson, R.A.1    Barber, A.C.2    Rizzi, M.3    Hippert, C.4    Xue, T.5    West, E.L.6
  • 13
    • 84883433950 scopus 로고    scopus 로고
    • Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina
    • COI: 1:CAS:528:DC%2BC3sXhtFCjtLfE, PID: 23873086
    • Gonzalez-Cordero A, West EL, Pearson RA, Duran Y, Carvalho LS, Chu CJ et al (2013) Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina. Nat Biotechnol 31(8):741–747
    • (2013) Nat Biotechnol , vol.31 , Issue.8 , pp. 741-747
    • Gonzalez-Cordero, A.1    West, E.L.2    Pearson, R.A.3    Duran, Y.4    Carvalho, L.S.5    Chu, C.J.6
  • 14
    • 84953253310 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration
    • COI: 1:CAS:528:DC%2BC2MXitVylsr3N, PID: 26699487, This is a pilot study primate models evaluating the clinical feasibility of transplantation of hESC-derived retinal sheets
    • • Shirai H, Mandai M, Matsushita K, Kuwahara A, Yonemura S, Nakano T et al (2016) Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration. Proc Natl Acad Sci U S A 113(1):E81–E90. This is a pilot study in primate models evaluating the clinical feasibility of transplantation of hESC-derived retinal sheets.
    • (2016) Proc Natl Acad Sci U S A , vol.113 , Issue.1 , pp. E81-E90
    • Shirai, H.1    Mandai, M.2    Matsushita, K.3    Kuwahara, A.4    Yonemura, S.5    Nakano, T.6
  • 15
    • 77949519072 scopus 로고    scopus 로고
    • Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat
    • Carr AJ, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL et al. (2009) Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One 4(12):e8152
    • (2009) PLoS One , vol.4 , Issue.12
    • Carr, A.J.1    Vugler, A.A.2    Hikita, S.T.3    Lawrence, J.M.4    Gias, C.5    Chen, L.L.6
  • 16
    • 79958284018 scopus 로고    scopus 로고
    • Intravitreal injection of autologous bone marrow-derived mononuclear cells for hereditary retinal dystrophy: a phase I trial
    • PID: 21293313
    • Siqueira RC, Messias A, Voltarelli JC, Scott IU, Jorge R (2011) Intravitreal injection of autologous bone marrow-derived mononuclear cells for hereditary retinal dystrophy: a phase I trial. Retina 31(6):1207–1214
    • (2011) Retina , vol.31 , Issue.6 , pp. 1207-1214
    • Siqueira, R.C.1    Messias, A.2    Voltarelli, J.C.3    Scott, I.U.4    Jorge, R.5
  • 17
    • 70350223975 scopus 로고    scopus 로고
    • Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells
    • COI: 1:CAS:528:DC%2BD1MXhsFenur7E, PID: 19658190
    • Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV et al (2009) Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells 27(10):2427–2434
    • (2009) Stem Cells , vol.27 , Issue.10 , pp. 2427-2434
    • Buchholz, D.E.1    Hikita, S.T.2    Rowland, T.J.3    Friedrich, A.M.4    Hinman, C.R.5    Johnson, L.V.6
  • 18
    • 65549115150 scopus 로고    scopus 로고
    • Generation of retinal cells from mouse and human induced pluripotent stem cells
    • COI: 1:CAS:528:DC%2BD1MXmtVait74%3D, PID: 19379795
    • Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H et al (2009) Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 458(3):126–131
    • (2009) Neurosci Lett , vol.458 , Issue.3 , pp. 126-131
    • Hirami, Y.1    Osakada, F.2    Takahashi, K.3    Okita, K.4    Yamanaka, S.5    Ikeda, H.6
  • 19
    • 84857643783 scopus 로고    scopus 로고
    • Embryonic stem cell trials for macular degeneration: a preliminary report
    • COI: 1:CAS:528:DC%2BC38XivVels7s%3D, PID: 22281388
    • Schwartz SD, Hubschman JP, Heilwell G, Franco-Cardenas V, Pan CK, Ostrick RM et al (2012) Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet 379(9817):713–720
    • (2012) Lancet , vol.379 , Issue.9817 , pp. 713-720
    • Schwartz, S.D.1    Hubschman, J.P.2    Heilwell, G.3    Franco-Cardenas, V.4    Pan, C.K.5    Ostrick, R.M.6
  • 20
    • 84929295709 scopus 로고    scopus 로고
    • Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients
    • COI: 1:CAS:528:DC%2BC2MXnsF2ns7w%3D, PID: 25937371
    • Song WK, Park K-M, Kim H-J, Lee JH, Choi J, Chong SY et al (2015) Treatment of macular degeneration using embryonic stem cell-derived retinal pigment epithelium: preliminary results in Asian patients. Stem cell reports 4(5):860–872
    • (2015) Stem cell reports , vol.4 , Issue.5 , pp. 860-872
    • Song, W.K.1    Park, K.-M.2    Kim, H.-J.3    Lee, J.H.4    Choi, J.5    Chong, S.Y.6
  • 21
    • 84923014395 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt’s macular dystrophy: follow-up of two open-label phase 1/2 studies
    • PID: 25458728, This study reports on the safety, graft survival, and possible biological activity of hESC-derived RPE cells transplanted patients
    • • Schwartz SD, Regillo CD, Lam BL, Eliott D, Rosenfeld PJ, Gregori NZ et al (2015) Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt’s macular dystrophy: follow-up of two open-label phase 1/2 studies. Lancet 385(9967):509–516. This study reports on the safety, graft survival, and possible biological activity of hESC-derived RPE cells transplanted in patients.
    • (2015) Lancet , vol.385 , Issue.9967 , pp. 509-516
    • Schwartz, S.D.1    Regillo, C.D.2    Lam, B.L.3    Eliott, D.4    Rosenfeld, P.J.5    Gregori, N.Z.6
  • 22
    • 84989869803 scopus 로고    scopus 로고
    • Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors
    • COI: 1:CAS:528:DC%2BC28Xhs1emsbnP, PID: 27701378, Together with the Santos-Ferreira et al. study, this paper demonstrated for the first time that transplanted photoreceptors do not integrate into the retina but engage exchange of cytoplasmic material with host cells
    • • Pearson RA, Gonzalez-Cordero A, West EL, Ribeiro JR, Aghaizu N, Goh D et al (2016) Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors. Nat Commun 7:13029. Together with the Santos-Ferreira et al. study, this paper demonstrated for the first time that transplanted photoreceptors do not integrate into the retina but engage in exchange of cytoplasmic material with host cells.
    • (2016) Nat Commun , vol.7 , pp. 13029
    • Pearson, R.A.1    Gonzalez-Cordero, A.2    West, E.L.3    Ribeiro, J.R.4    Aghaizu, N.5    Goh, D.6
  • 23
    • 84989849627 scopus 로고    scopus 로고
    • Retinal transplantation of photoreceptors results in donor-host cytoplasmic exchange
    • COI: 1:CAS:528:DC%2BC28Xhs1emsbnN, PID: 27701381, Together with the Pearson et al. study, this paper demonstrated for the first time that transplanted photoreceptors do not integrate into the retina but engage exchange of cytoplasmic material with host cells
    • • Santos-Ferreira T, Llonch S, Borsch O, Postel K, Haas J, Ader M (2016) Retinal transplantation of photoreceptors results in donor-host cytoplasmic exchange. Nat Commun 7:13028. Together with the Pearson et al. study, this paper demonstrated for the first time that transplanted photoreceptors do not integrate into the retina but engage in exchange of cytoplasmic material with host cells.
    • (2016) Nat Commun , vol.7 , pp. 13028
    • Santos-Ferreira, T.1    Llonch, S.2    Borsch, O.3    Postel, K.4    Haas, J.5    Ader, M.6
  • 24
    • 84955322229 scopus 로고    scopus 로고
    • The Argus((R)) II retinal prosthesis system
    • PID: 26404104
    • Luo YH, da Cruz L (2016) The Argus((R)) II retinal prosthesis system. Prog Retin Eye Res 50:89–107
    • (2016) Prog Retin Eye Res , vol.50 , pp. 89-107
    • Luo, Y.H.1    da Cruz, L.2
  • 25
    • 0023182049 scopus 로고
    • A common progenitor for neurons and glia persists in rat retina late in development
    • COI: 1:STN:280:DyaL2s3lvVahtw%3D%3D, PID: 3600789
    • Turner DL, Cepko CL (1987) A common progenitor for neurons and glia persists in rat retina late in development. Nature 328(6126):131–136
    • (1987) Nature , vol.328 , Issue.6126 , pp. 131-136
    • Turner, D.L.1    Cepko, C.L.2
  • 26
    • 0024438547 scopus 로고
    • Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina
    • COI: 1:STN:280:DyaK3c%2FjtlOlug%3D%3D, PID: 2478403
    • Wetts R, Serbedzija GN, Fraser SE (1989) Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina. Dev Biol 136(1):254–263
    • (1989) Dev Biol , vol.136 , Issue.1 , pp. 254-263
    • Wetts, R.1    Serbedzija, G.N.2    Fraser, S.E.3
  • 27
    • 0032528384 scopus 로고    scopus 로고
    • The genetic sequence of retinal development in the ciliary margin of the Xenopus eye
    • COI: 1:CAS:528:DyaK1cXltFyntb4%3D, PID: 9698439
    • Perron M, Kanekar S, Vetter ML, Harris WA (1998) The genetic sequence of retinal development in the ciliary margin of the Xenopus eye. Dev Biol 199(2):185–200
    • (1998) Dev Biol , vol.199 , Issue.2 , pp. 185-200
    • Perron, M.1    Kanekar, S.2    Vetter, M.L.3    Harris, W.A.4
  • 28
    • 82755171268 scopus 로고    scopus 로고
    • Fate restriction and multipotency in retinal stem cells
    • COI: 1:CAS:528:DC%2BC3MXhsFOns7jJ, PID: 22136930
    • Centanin L, Hoeckendorf B, Wittbrodt J (2011) Fate restriction and multipotency in retinal stem cells. Cell Stem Cell 9(6):553–562
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 553-562
    • Centanin, L.1    Hoeckendorf, B.2    Wittbrodt, J.3
  • 29
    • 84990043586 scopus 로고    scopus 로고
    • Zebrafish models of retinal disease
    • This is an excellent and comprehensive review on zebrafish models for retinal diseases
    • • Link BA, Collery RF (2015) Zebrafish models of retinal disease. Annu Rev Vis Sci 1(1):125–153. This is an excellent and comprehensive review on zebrafish models for retinal diseases.
    • (2015) Annu Rev Vis Sci , vol.1 , Issue.1 , pp. 125-153
    • Link, B.A.1    Collery, R.F.2
  • 31
    • 84898458935 scopus 로고    scopus 로고
    • Zebrafish—on the move towards ophthalmological research
    • COI: 1:STN:280:DC%2BC2cvislyltQ%3D%3D, PID: 24503724
    • Chhetri J, Jacobson G, Gueven N (2014) Zebrafish—on the move towards ophthalmological research. Eye 28(4):367–380
    • (2014) Eye , vol.28 , Issue.4 , pp. 367-380
    • Chhetri, J.1    Jacobson, G.2    Gueven, N.3
  • 32
    • 37249048320 scopus 로고    scopus 로고
    • A mutation in the cone-specific pde 6 gene causes rapid cone photoreceptor degeneration in zebrafish
    • COI: 1:CAS:528:DC%2BD1cXmsFc%3D, PID: 18077698
    • Stearns G, Evangelista M, Fadool JM, Brockerhoff SE (2007) A mutation in the cone-specific pde 6 gene causes rapid cone photoreceptor degeneration in zebrafish. J Neurosci 27(50):13866–13874
    • (2007) J Neurosci , vol.27 , Issue.50 , pp. 13866-13874
    • Stearns, G.1    Evangelista, M.2    Fadool, J.M.3    Brockerhoff, S.E.4
  • 34
    • 84997426807 scopus 로고    scopus 로고
    • A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi
    • COI: 1:CAS:528:DC%2BC28XitFSns7%2FJ, PID: 27882921, This is a good example of the benefit of zebrafish as a model for human ciliopathies
    • • Stoetzel C, Bär S, De Craene J-O, Scheidecker S, Etard C, Chicher J et al (2016) A mutation in VPS15 (PIK3R4) causes a ciliopathy and affects IFT20 release from the cis-Golgi. Nat Commun 7:13586. This is a good example of the benefit of zebrafish as a model for human ciliopathies.
    • (2016) Nat Commun , vol.7 , pp. 13586
    • Stoetzel, C.1    Bär, S.2    De Craene, J.-O.3    Scheidecker, S.4    Etard, C.5    Chicher, J.6
  • 35
    • 84998813179 scopus 로고    scopus 로고
    • Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21)
    • COI: 1:CAS:528:DC%2BC28XitFert73F, PID: 27008867, This paper nicely illustrates the usefulness of zebrafish for phenotype–genotype correlation studies
    • • Heon E, Kim G, Qin S, Garrison JE, Tavares E, Vincent A et al (2016) Mutations in C8ORF37 cause Bardet Biedl syndrome (BBS21). Hum Mol Genet 25(11):2283–2294. This paper nicely illustrates the usefulness of zebrafish for phenotype–genotype correlation studies.
    • (2016) Hum Mol Genet , vol.25 , Issue.11 , pp. 2283-2294
    • Heon, E.1    Kim, G.2    Qin, S.3    Garrison, J.E.4    Tavares, E.5    Vincent, A.6
  • 36
    • 84986206034 scopus 로고    scopus 로고
    • Arl13b interacts with Vangl2 to regulate cilia and photoreceptor outer segment length in zebrafish
    • Song P, Dudinsky L, Fogerty J, Gaivin R, Perkins BD (2016) Arl13b interacts with Vangl2 to regulate cilia and photoreceptor outer segment length in zebrafish. Investig Opthalmology Vis Sci 57(10):4517
    • (2016) Investig Opthalmology Vis Sci , vol.57 , Issue.10 , pp. 4517
    • Song, P.1    Dudinsky, L.2    Fogerty, J.3    Gaivin, R.4    Perkins, B.D.5
  • 37
    • 84938681395 scopus 로고    scopus 로고
    • An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
    • COI: 1:CAS:528:DC%2BC2MXht1WrurzJ, PID: 26167768, This work illustrates the advantage of zebrafish for large-scale screening approaches, to identify roles of genes involved retinal diseases
    • • Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen T-MT, Racher H et al (2015) An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. Nat Cell Biol 17(8):1074–1087. This work illustrates the advantage of zebrafish for large-scale screening approaches, to identify roles of genes involved in retinal diseases.
    • (2015) Nat Cell Biol , vol.17 , Issue.8 , pp. 1074-1087
    • Wheway, G.1    Schmidts, M.2    Mans, D.A.3    Szymanska, K.4    Nguyen, T.-M.T.5    Racher, H.6
  • 38
    • 78649928382 scopus 로고    scopus 로고
    • Hypoxia-induced retinopathy model in adult zebrafish
    • COI: 1:CAS:528:DC%2BC3cXhsFSku7nN, PID: 21127484
    • Cao Z, Jensen LD, Rouhi P, Hosaka K, Lanne T, Steffensen JF et al (2010) Hypoxia-induced retinopathy model in adult zebrafish. Nat Protoc 5(12):1903–1910
    • (2010) Nat Protoc , vol.5 , Issue.12 , pp. 1903-1910
    • Cao, Z.1    Jensen, L.D.2    Rouhi, P.3    Hosaka, K.4    Lanne, T.5    Steffensen, J.F.6
  • 39
    • 50249086022 scopus 로고    scopus 로고
    • Hypoxia-induced retinal angiogenesis in zebrafish as a model to study retinopathy
    • Cao R, Jensen LD, Soll I, Hauptmann G, Cao Y (2008) Hypoxia-induced retinal angiogenesis in zebrafish as a model to study retinopathy. PLoS One 3(7):e2748
    • (2008) PLoS One , vol.3 , Issue.7
    • Cao, R.1    Jensen, L.D.2    Soll, I.3    Hauptmann, G.4    Cao, Y.5
  • 40
    • 77952183381 scopus 로고    scopus 로고
    • von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish
    • van Rooijen E, Voest EE, Logister I, Bussmann J, Korving J, van Eeden FJ et al (2010) von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Dis Model Mech 3(5–6):343–353
    • (2010) Dis Model Mech , vol.3 , Issue.5-6 , pp. 343-353
    • van Rooijen, E.1    Voest, E.E.2    Logister, I.3    Bussmann, J.4    Korving, J.5    van Eeden, F.J.6
  • 41
    • 34548157450 scopus 로고    scopus 로고
    • Induction of hyperglycaemia in zebrafish (Danio rerio) leads to morphological changes in the retina
    • COI: 1:STN:280:DC%2BD2srgtF2msg%3D%3D, PID: 17721755
    • Gleeson M, Connaughton V, Arneson LS (2007) Induction of hyperglycaemia in zebrafish (Danio rerio) leads to morphological changes in the retina. Acta Diabetol 44(3):157–163
    • (2007) Acta Diabetol , vol.44 , Issue.3 , pp. 157-163
    • Gleeson, M.1    Connaughton, V.2    Arneson, L.S.3
  • 42
    • 77949439159 scopus 로고    scopus 로고
    • Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy
    • COI: 1:CAS:528:DC%2BC3cXhsFyhtLnN, PID: 20142328
    • Alvarez Y, Chen K, Reynolds AL, Waghorne N, O’Connor JJ, Kennedy BN (2010) Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy. Dis Model Mech 3(3–4):236–245
    • (2010) Dis Model Mech , vol.3 , Issue.3-4 , pp. 236-245
    • Alvarez, Y.1    Chen, K.2    Reynolds, A.L.3    Waghorne, N.4    O’Connor, J.J.5    Kennedy, B.N.6
  • 43
    • 84963945580 scopus 로고    scopus 로고
    • Zebrafish (Danio rerio) embryo as a platform for the identification of novel angiogenesis inhibitors of retinal vascular diseases
    • COI: 1:CAS:528:DC%2BC28XmtFCnsbc%3D
    • Rezzola S, Paganini G, Semeraro F, Presta M, Tobia C (2016) Zebrafish (Danio rerio) embryo as a platform for the identification of novel angiogenesis inhibitors of retinal vascular diseases. Biochim Biophys Acta - Mol Basis Dis 1862(7):1291–1296
    • (2016) Biochim Biophys Acta - Mol Basis Dis , vol.1862 , Issue.7 , pp. 1291-1296
    • Rezzola, S.1    Paganini, G.2    Semeraro, F.3    Presta, M.4    Tobia, C.5
  • 44
    • 84863079208 scopus 로고    scopus 로고
    • Dysmorphic photoreceptors in a P23H mutant rhodopsin model of retinitis pigmentosa are metabolically active and capable of regenerating to reverse retinal degeneration
    • COI: 1:CAS:528:DC%2BC38XisFantbY%3D, PID: 22323724
    • Lee DC, Vazquez-Chona FR, Ferrell WD, Tam BM, Jones BW, Marc RE et al (2012) Dysmorphic photoreceptors in a P23H mutant rhodopsin model of retinitis pigmentosa are metabolically active and capable of regenerating to reverse retinal degeneration. J Neurosci 32(6):2121–2128
    • (2012) J Neurosci , vol.32 , Issue.6 , pp. 2121-2128
    • Lee, D.C.1    Vazquez-Chona, F.R.2    Ferrell, W.D.3    Tam, B.M.4    Jones, B.W.5    Marc, R.E.6
  • 45
    • 84871952083 scopus 로고    scopus 로고
    • Generation of transgenic X. laevis models of retinal degeneration
    • COI: 1:CAS:528:DC%2BC3sXksFWhtbs%3D, PID: 23150364
    • Tam BM, Lai CC-L, Zong Z, Moritz OL (2013) Generation of transgenic X. laevis models of retinal degeneration. Methods Mol Biol 935:113–125
    • (2013) Methods Mol Biol , vol.935 , pp. 113-125
    • Tam, B.M.1    Lai, C.C.-L.2    Zong, Z.3    Moritz, O.L.4
  • 46
    • 77449143587 scopus 로고    scopus 로고
    • Fourier domain optical coherence tomography as a noninvasive means for in vivo detection of retinal degeneration in Xenopus laevis tadpoles
    • Lee DC, Xu J, Sarunic MV, Moritz OL (2010) Fourier domain optical coherence tomography as a noninvasive means for in vivo detection of retinal degeneration in Xenopus laevis tadpoles. Investig Opthalmology Vis Sci 51(2):1066
    • (2010) Investig Opthalmology Vis Sci , vol.51 , Issue.2 , pp. 1066
    • Lee, D.C.1    Xu, J.2    Sarunic, M.V.3    Moritz, O.L.4
  • 47
    • 33748100274 scopus 로고    scopus 로고
    • Characterization of rhodopsin P23H-induced retinal degeneration in a Xenopus laevis model of retinitis pigmentosa
    • PID: 16877386
    • Tam BM, Moritz OL (2006) Characterization of rhodopsin P23H-induced retinal degeneration in a Xenopus laevis model of retinitis pigmentosa. Invest Ophthalmol Vis Sci 47(8):3234–3241
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , Issue.8 , pp. 3234-3241
    • Tam, B.M.1    Moritz, O.L.2
  • 48
    • 34548169402 scopus 로고    scopus 로고
    • Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin
    • COI: 1:CAS:528:DC%2BD2sXhtVSnsLnI, PID: 17715341
    • Tam BM, Moritz OL (2007) Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin. J Neurosci 27(34):9043–9053
    • (2007) J Neurosci , vol.27 , Issue.34 , pp. 9043-9053
    • Tam, B.M.1    Moritz, O.L.2
  • 49
    • 84950335519 scopus 로고    scopus 로고
    • Light induces ultrastructural changes in rod outer and inner segments, including autophagy, in a transgenic Xenopus laevis P23H rhodopsin model of retinitis pigmentosa
    • COI: 1:CAS:528:DC%2BC2sXkt1Oruw%3D%3D, This study is a good example of the benefit ofXenopusto study the mechanisms underlying photoreceptor cell death a model of retinitis pigmentosa
    • • Bogéa TH, Wen RH, Moritz OL (2015) Light induces ultrastructural changes in rod outer and inner segments, including autophagy, in a transgenic Xenopus laevis P23H rhodopsin model of retinitis pigmentosa. Investig Opthalmology Vis Sci 56(13):7947. This study is a good example of the benefit of Xenopus to study the mechanisms underlying photoreceptor cell death in a model of retinitis pigmentosa.
    • (2015) Investig Opthalmology Vis Sci. , vol.56 , Issue.13 , pp. 7947
    • Bogéa, T.H.1    Wen, R.H.2    Moritz, O.L.3
  • 50
    • 84911489013 scopus 로고    scopus 로고
    • Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration
    • (,),., Strauß, O, editor
    • Arango-Gonzalez B, Trifunović D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, et al (2014) Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. Strauß O, editor. PLoS One 9(11):e112142
    • (2014) PLoS One , vol.9 , Issue.11
    • Arango-Gonzalez, B.1    Trifunović, D.2    Sahaboglu, A.3    Kranz, K.4    Michalakis, S.5    Farinelli, P.6
  • 51
    • 84907484404 scopus 로고    scopus 로고
    • Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa
    • PID: 25274813, COI: 1:CAS:528:DC%2BC2cXhslCntbjP
    • Tam BM, Noorwez SM, Kaushal S, Kono M, Moritz OL (2014) Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa. J Neurosci 34(40):13336–13348
    • (2014) J Neurosci , vol.34 , Issue.40 , pp. 13336-13348
    • Tam, B.M.1    Noorwez, S.M.2    Kaushal, S.3    Kono, M.4    Moritz, O.L.5
  • 52
    • 0037743559 scopus 로고    scopus 로고
    • Opsin activation as a cause of congenital night blindness
    • COI: 1:CAS:528:DC%2BD3sXkvVKmtL0%3D, PID: 12778053
    • Jin S, Cornwall MC, Oprian DD (2003) Opsin activation as a cause of congenital night blindness. Nat Neurosci 6(7):731–735
    • (2003) Nat Neurosci , vol.6 , Issue.7 , pp. 731-735
    • Jin, S.1    Cornwall, M.C.2    Oprian, D.D.3
  • 53
    • 84943338992 scopus 로고    scopus 로고
    • Current progress in deciphering importance of VLC-PUFA in the retina
    • PID: 26427405
    • Bennett LD, Anderson RE (2016) Current progress in deciphering importance of VLC-PUFA in the retina. Adv Exp Med Biol 854:145–151
    • (2016) Adv Exp Med Biol , vol.854 , pp. 145-151
    • Bennett, L.D.1    Anderson, R.E.2
  • 54
    • 84902504255 scopus 로고    scopus 로고
    • Mutant ELOVL4 that causes autosomal dominant stargardt-3 macular dystrophy is misrouted to rod outer segment disks
    • COI: 1:CAS:528:DC%2BC2cXhsVSkur%2FI, PID: 24833735
    • Agbaga MP, Tam BM, Wong JS, Yang LL, Anderson RE, Moritz OL (2014) Mutant ELOVL4 that causes autosomal dominant stargardt-3 macular dystrophy is misrouted to rod outer segment disks. Invest Ophthalmol Vis Sci 55(6):3669–3680
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , Issue.6 , pp. 3669-3680
    • Agbaga, M.P.1    Tam, B.M.2    Wong, J.S.3    Yang, L.L.4    Anderson, R.E.5    Moritz, O.L.6
  • 55
    • 0034502787 scopus 로고    scopus 로고
    • Cellular proliferation and neurogenesis in the injured retina of adult zebrafish
    • Cameron DA Cellular proliferation and neurogenesis in the injured retina of adult zebrafish. Vis Neurosci 17(5):789–797
    • Vis Neurosci , vol.17 , Issue.5 , pp. 789-797
    • Cameron, D.A.1
  • 56
    • 4444300313 scopus 로고    scopus 로고
    • An element in the 1-tubulin promoter is necessary for retinal expression during optic nerve regeneration but not after eye injury in the adult zebrafish
    • COI: 1:CAS:528:DC%2BD2cXns1Oqsbs%3D, PID: 15342733
    • Senut M-C, Gulati-Leekha A, Goldman D (2004) An element in the 1-tubulin promoter is necessary for retinal expression during optic nerve regeneration but not after eye injury in the adult zebrafish. J Neurosci 24(35):7663–7673
    • (2004) J Neurosci , vol.24 , Issue.35 , pp. 7663-7673
    • Senut, M.-C.1    Gulati-Leekha, A.2    Goldman, D.3
  • 57
    • 33847141503 scopus 로고    scopus 로고
    • Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish
    • COI: 1:CAS:528:DC%2BD2sXitl2nsL8%3D, PID: 17301179
    • Fimbel SM, Montgomery JE, Burket CT, Hyde DR (2007) Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish. J Neurosci 27(7):1712–1724
    • (2007) J Neurosci , vol.27 , Issue.7 , pp. 1712-1724
    • Fimbel, S.M.1    Montgomery, J.E.2    Burket, C.T.3    Hyde, D.R.4
  • 58
    • 84964598987 scopus 로고    scopus 로고
    • Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons
    • COI: 1:CAS:528:DC%2BC28XmsFyktbw%3D, PID: 27094545, Based on the use of different retinal injury paradigms, this study revealed that addition to regenerate lost retinal cells, Müller glia-derived progenitors also generate unneeded neurons
    • • Powell C, Cornblath E, Elsaeidi F, Wan J, Goldman D (2016) Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons. Sci Rep 6:24851. Based on the use of different retinal injury paradigms, this study revealed that in addition to regenerate lost retinal cells, Müller glia-derived progenitors also generate unneeded neurons.
    • (2016) Sci Rep , vol.6 , pp. 24851
    • Powell, C.1    Cornblath, E.2    Elsaeidi, F.3    Wan, J.4    Goldman, D.5
  • 59
    • 31044431898 scopus 로고    scopus 로고
    • Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish
    • COI: 1:CAS:528:DC%2BD28Xos1aitQ%3D%3D, PID: 16199033
    • Vihtelic TS, Soverly JE, Kassen SC, Hyde DR (2006) Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish. Exp Eye Res 82(4):558–575
    • (2006) Exp Eye Res , vol.82 , Issue.4 , pp. 558-575
    • Vihtelic, T.S.1    Soverly, J.E.2    Kassen, S.C.3    Hyde, D.R.4
  • 60
    • 0033839682 scopus 로고    scopus 로고
    • Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina
    • COI: 1:STN:280:DC%2BD3cvntlajsg%3D%3D, PID: 10942883
    • Vihtelic TS, Hyde DR (2000) Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina. J Neurobiol 44(3):289–307
    • (2000) J Neurobiol , vol.44 , Issue.3 , pp. 289-307
    • Vihtelic, T.S.1    Hyde, D.R.2
  • 61
    • 34548301654 scopus 로고    scopus 로고
    • Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish
    • COI: 1:CAS:528:DC%2BD2sXosF2jtrk%3D, PID: 17565703
    • Kassen SC, Ramanan V, Montgomery JE, Burket TC, Liu C-G, Vihtelic TS et al (2007) Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Dev Neurobiol 67(8):1009–1031
    • (2007) Dev Neurobiol , vol.67 , Issue.8 , pp. 1009-1031
    • Kassen, S.C.1    Ramanan, V.2    Montgomery, J.E.3    Burket, T.C.4    Liu, C.-G.5    Vihtelic, T.S.6
  • 62
    • 34347361689 scopus 로고    scopus 로고
    • Late-stage neuronal progenitors in the retina are radial Muller glia that function as retinal stem cells
    • COI: 1:CAS:528:DC%2BD2sXnsVyjt7Y%3D, PID: 17596452
    • Bernardos RL, Barthel LK, Meyers JR, Raymond PA (2007) Late-stage neuronal progenitors in the retina are radial Muller glia that function as retinal stem cells. J Neurosci 27(26):7028–7040
    • (2007) J Neurosci , vol.27 , Issue.26 , pp. 7028-7040
    • Bernardos, R.L.1    Barthel, L.K.2    Meyers, J.R.3    Raymond, P.A.4
  • 63
    • 84859482783 scopus 로고    scopus 로고
    • Characterization of multiple light damage paradigms reveals regional differences in photoreceptor loss
    • COI: 1:CAS:528:DC%2BC38XlsFGguro%3D, PID: 22425727
    • Thomas JL, Nelson CM, Luo X, Hyde DR, Thummel R (2012) Characterization of multiple light damage paradigms reveals regional differences in photoreceptor loss. Exp Eye Res 97(1):105–116
    • (2012) Exp Eye Res , vol.97 , Issue.1 , pp. 105-116
    • Thomas, J.L.1    Nelson, C.M.2    Luo, X.3    Hyde, D.R.4    Thummel, R.5
  • 64
    • 84905436381 scopus 로고    scopus 로고
    • Technical brief: constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish
    • COI: 1:CAS:528:DC%2BC2cXhvFKgtrvI, PID: 25324680
    • Rajaram K, Summerbell ER, Patton JG (2014) Technical brief: constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish. Mol Vis 20:1075–1084
    • (2014) Mol Vis , vol.20 , pp. 1075-1084
    • Rajaram, K.1    Summerbell, E.R.2    Patton, J.G.3
  • 65
    • 84896734193 scopus 로고    scopus 로고
    • Characterization of light lesion paradigms and optical coherence tomography as tools to study adult retina regeneration in zebrafish
    • (,),., Neuhauss, SC, editor
    • Weber A, Hochmann S, Cimalla P, Gärtner M, Kuscha V, Hans S, et al (2013) Characterization of light lesion paradigms and optical coherence tomography as tools to study adult retina regeneration in zebrafish. Neuhauss SC, editor. PLoS One 8(11):e80483
    • (2013) PLoS One , vol.8 , Issue.11
    • Weber, A.1    Hochmann, S.2    Cimalla, P.3    Gärtner, M.4    Kuscha, V.5    Hans, S.6
  • 66
    • 33748630498 scopus 로고    scopus 로고
    • Molecular characterization of retinal stem cells and their niches in adult zebrafish
    • PID: 16872490, COI: 1:CAS:528:DC%2BD28Xot1Oru7Y%3D
    • Raymond PA, Barthel LK, Bernardos RL, Perkowski JJ (2006) Molecular characterization of retinal stem cells and their niches in adult zebrafish. BMC Dev Biol 6:36
    • (2006) BMC Dev Biol , vol.6 , pp. 36
    • Raymond, P.A.1    Barthel, L.K.2    Bernardos, R.L.3    Perkowski, J.J.4
  • 68
    • 77956624063 scopus 로고    scopus 로고
    • Animal models for retinitis pigmentosa induced by MNU; disease progression, mechanisms and therapeutic trials
    • COI: 1:CAS:528:DC%2BC3cXhtVGksbvM, PID: 20503181
    • Tsubura A, Yoshizawa K, Kuwata M, Uehara N (2010) Animal models for retinitis pigmentosa induced by MNU; disease progression, mechanisms and therapeutic trials. Histol Histopathol 25(7):933–944
    • (2010) Histol Histopathol , vol.25 , Issue.7 , pp. 933-944
    • Tsubura, A.1    Yoshizawa, K.2    Kuwata, M.3    Uehara, N.4
  • 69
    • 84881532201 scopus 로고    scopus 로고
    • Characteristics of rod regeneration in a novel zebrafish retinal degeneration model using N-methyl-N-nitrosourea (MNU). Thummel R, editor
    • Tappeiner C, Balmer J, Iglicki M, Schuerch K, Jazwinska A, Enzmann V, et al (2013) Characteristics of rod regeneration in a novel zebrafish retinal degeneration model using N-methyl-N-nitrosourea (MNU). Thummel R, editor. PLoS One 8(8):e71064
    • (2013) PLoS One , vol.8 , Issue.8
    • Tappeiner, C.1    Balmer, J.2    Iglicki, M.3    Schuerch, K.4    Jazwinska, A.5    Enzmann, V.6
  • 70
    • 84908320683 scopus 로고    scopus 로고
    • Methylnitrosourea (MNU)-induced retinal degeneration and regeneration in the zebrafish: histological and functional characteristics
    • Maurer E, Tschopp M, Tappeiner C, Sallin P, Jazwinska A, Enzmann V (2014) Methylnitrosourea (MNU)-induced retinal degeneration and regeneration in the zebrafish: histological and functional characteristics. J Vis Exp (92):e51909
    • (2014) J Vis Exp , Issue.92
    • Maurer, E.1    Tschopp, M.2    Tappeiner, C.3    Sallin, P.4    Jazwinska, A.5    Enzmann, V.6
  • 71
    • 77949400126 scopus 로고    scopus 로고
    • A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors
    • COI: 1:CAS:528:DC%2BC3cXitFGjurw%3D, PID: 20058308
    • Montgomery JE, Parsons MJ, Hyde DR (2010) A novel model of retinal ablation demonstrates that the extent of rod cell death regulates the origin of the regenerated zebrafish rod photoreceptors. J Comp Neurol 518(6):800–814
    • (2010) J Comp Neurol , vol.518 , Issue.6 , pp. 800-814
    • Montgomery, J.E.1    Parsons, M.J.2    Hyde, D.R.3
  • 72
    • 84873813858 scopus 로고    scopus 로고
    • Regeneration of cone photoreceptors when cell ablation is primarily restricted to a particular cone subtype
    • (,),., Karl, MO, editor
    • Fraser B, DuVal MG, Wang H, Allison WT (2013) Regeneration of cone photoreceptors when cell ablation is primarily restricted to a particular cone subtype. Karl MO, editor. PLoS One 8(1):e55410
    • (2013) PLoS One , vol.8 , Issue.1
    • Fraser, B.1    DuVal, M.G.2    Wang, H.3    Allison, W.T.4
  • 73
    • 44949256438 scopus 로고    scopus 로고
    • Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies
    • COI: 1:CAS:528:DC%2BD1cXmvVemtrg%3D, PID: 18536643
    • Curado S, Stainier DYR, Anderson RM (2008) Nitroreductase-mediated cell/tissue ablation in zebrafish: a spatially and temporally controlled ablation method with applications in developmental and regeneration studies. Nat Protoc 3(6):948–954
    • (2008) Nat Protoc , vol.3 , Issue.6 , pp. 948-954
    • Curado, S.1    Stainier, D.Y.R.2    Anderson, R.M.3
  • 74
    • 33847235763 scopus 로고    scopus 로고
    • Regeneration of the amphibian retina: role of tissue interaction and related signaling molecules on RPE transdifferentiation
    • Araki M (2007) Regeneration of the amphibian retina: role of tissue interaction and related signaling molecules on RPE transdifferentiation. Develop Growth Differ 49(2):109–120
    • (2007) Develop Growth Differ , vol.49 , Issue.2 , pp. 109-120
    • Araki, M.1
  • 75
    • 33846915136 scopus 로고    scopus 로고
    • Neural retinal regeneration in the anuran amphibian Xenopus laevis post-metamorphosis: transdifferentiation of retinal pigmented epithelium regenerates the neural retina
    • COI: 1:CAS:528:DC%2BD2sXhvVGgtrY%3D, PID: 17184765
    • Yoshii C, Ueda Y, Okamoto M, Araki M (2007) Neural retinal regeneration in the anuran amphibian Xenopus laevis post-metamorphosis: transdifferentiation of retinal pigmented epithelium regenerates the neural retina. Dev Biol 303(1):45–56
    • (2007) Dev Biol , vol.303 , Issue.1 , pp. 45-56
    • Yoshii, C.1    Ueda, Y.2    Okamoto, M.3    Araki, M.4
  • 76
    • 66949131761 scopus 로고    scopus 로고
    • Retinal regeneration in the Xenopus laevis tadpole: a new model system
    • COI: 1:CAS:528:DC%2BD1MXmtlCrtLc%3D, PID: 19461929
    • Vergara MN, Del Rio-Tsonis K (2009) Retinal regeneration in the Xenopus laevis tadpole: a new model system. Mol Vis 15:1000–1013
    • (2009) Mol Vis , vol.15 , pp. 1000-1013
    • Vergara, M.N.1    Del Rio-Tsonis, K.2
  • 77
    • 84865308748 scopus 로고    scopus 로고
    • Transgenic Xenopus laevis with the ef1-α promoter as an experimental tool for amphibian retinal regeneration study
    • COI: 1:CAS:528:DC%2BC38Xht1Wrtr7J, PID: 22422643
    • Ueda Y, Mizuno N, Araki M (2012) Transgenic Xenopus laevis with the ef1-α promoter as an experimental tool for amphibian retinal regeneration study. Genesis 50(8):642–650
    • (2012) Genesis , vol.50 , Issue.8 , pp. 642-650
    • Ueda, Y.1    Mizuno, N.2    Araki, M.3
  • 78
    • 84902106439 scopus 로고    scopus 로고
    • Retinal stem/progenitor cells in the ciliary marginal zone complete retinal regeneration: a study of retinal regeneration in a novel animal model
    • PID: 24488715, This study revealed that the entire retina can regenerate after complete retinectomy adultX. tropicalis. This work also highlighted differences the regeneration process betweenX. laevisandX. tropicalis
    • • Miyake A, Araki M (2014) Retinal stem/progenitor cells in the ciliary marginal zone complete retinal regeneration: a study of retinal regeneration in a novel animal model. Dev Neurobiol. 74(7):739–756. This study revealed that the entire retina can regenerate after complete retinectomy in adult X. tropicalis. This work also highlighted differences in the regeneration process between X. laevis and X. tropicalis.
    • (2014) Dev Neurobiol. , vol.74 , Issue.7 , pp. 739-756
    • Miyake, A.1    Araki, M.2
  • 79
    • 67649440875 scopus 로고    scopus 로고
    • Retina and lens regeneration in anuran amphibians
    • PID: 19095070
    • Filoni S (2009) Retina and lens regeneration in anuran amphibians. Semin Cell Dev Biol 20(5):528–534
    • (2009) Semin Cell Dev Biol , vol.20 , Issue.5 , pp. 528-534
    • Filoni, S.1
  • 80
    • 79953736751 scopus 로고    scopus 로고
    • The Retinal Homeobox (Rx) gene is necessary for retinal regeneration
    • COI: 1:CAS:528:DC%2BC3MXks1Whtbk%3D, PID: 21334323
    • Martinez-De Luna RI, Kelly LE, El-Hodiri HM (2011) The Retinal Homeobox (Rx) gene is necessary for retinal regeneration. Dev Biol 353(1):10–18
    • (2011) Dev Biol , vol.353 , Issue.1 , pp. 10-18
    • Martinez-De Luna, R.I.1    Kelly, L.E.2    El-Hodiri, H.M.3
  • 81
    • 84875423711 scopus 로고    scopus 로고
    • Xenopus laevis tadpoles can regenerate neural retina lost after physical excision but cannot regenerate photoreceptors lost through targeted ablation
    • COI: 1:CAS:528:DC%2BC3sXnsVCgsb4%3D, PID: 23425694
    • Lee DC, Hamm LM, Moritz OL (2013) Xenopus laevis tadpoles can regenerate neural retina lost after physical excision but cannot regenerate photoreceptors lost through targeted ablation. Invest Ophthalmol Vis Sci 54(3):1859–1867
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , Issue.3 , pp. 1859-1867
    • Lee, D.C.1    Hamm, L.M.2    Moritz, O.L.3
  • 82
    • 59449091789 scopus 로고    scopus 로고
    • Controlled rod cell ablation in transgenic Xenopus laevis
    • PID: 18836175
    • Hamm LM, Tam BM, Moritz OL (2009) Controlled rod cell ablation in transgenic Xenopus laevis. Invest Ophthalmol Vis Sci 50(2):885–892
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , Issue.2 , pp. 885-892
    • Hamm, L.M.1    Tam, B.M.2    Moritz, O.L.3
  • 83
    • 0017729874 scopus 로고
    • Growth of the adult goldfish eye. III. Source of the new retinal cells
    • COI: 1:STN:280:DyaE1c%2Fis12gsA%3D%3D, PID: 915042
    • Johns PR (1977) Growth of the adult goldfish eye. III. Source of the new retinal cells. J Comp Neurol 176(3):343–357
    • (1977) J Comp Neurol , vol.176 , Issue.3 , pp. 343-357
    • Johns, P.R.1
  • 84
    • 0015107579 scopus 로고
    • The growth of the retina in Xenopus laevis: an autoradiographic study
    • COI: 1:STN:280:DyaE3M3nsFertg%3D%3D, PID: 5565078
    • Straznicky K, Gaze RM (1971) The growth of the retina in Xenopus laevis: an autoradiographic study. J Embryol Exp Morphol 26(1):67–79
    • (1971) J Embryol Exp Morphol , vol.26 , Issue.1 , pp. 67-79
    • Straznicky, K.1    Gaze, R.M.2
  • 85
    • 84885067381 scopus 로고    scopus 로고
    • The ciliary marginal zone (CMZ) in development and regeneration of the vertebrate eye
    • COI: 1:CAS:528:DC%2BC3sXhvVWktr%2FN, PID: 24025744
    • Fischer AJ, Bosse JL, El-Hodiri HM (2013) The ciliary marginal zone (CMZ) in development and regeneration of the vertebrate eye. Exp Eye Res 116:199–204
    • (2013) Exp Eye Res , vol.116 , pp. 199-204
    • Fischer, A.J.1    Bosse, J.L.2    El-Hodiri, H.M.3
  • 86
    • 0014323345 scopus 로고
    • Differential addition of cells to the retina in Rana pipiens tadpoles
    • COI: 1:STN:280:DyaF1czpsl2ksg%3D%3D, PID: 5672879
    • Hollyfield JG (1968) Differential addition of cells to the retina in Rana pipiens tadpoles. Dev Biol 18(2):163–179
    • (1968) Dev Biol , vol.18 , Issue.2 , pp. 163-179
    • Hollyfield, J.G.1
  • 87
    • 0015014358 scopus 로고
    • Differential growth of the neural retina in Xenopus laevis larvae
    • COI: 1:CAS:528:DyaE3MXhtVyksb4%3D, PID: 5553368
    • Hollyfield JG (1971) Differential growth of the neural retina in Xenopus laevis larvae. Dev Biol 24(2):264–286
    • (1971) Dev Biol , vol.24 , Issue.2 , pp. 264-286
    • Hollyfield, J.G.1
  • 88
    • 84978633412 scopus 로고    scopus 로고
    • Identification of radial glia progenitors in the developing and adult retina of sharks
    • Sánchez-Farías N, Candal E (2016) Identification of radial glia progenitors in the developing and adult retina of sharks. Front Neuroanat 20:10
    • (2016) Front Neuroanat , vol.20 , pp. 10
    • Sánchez-Farías, N.1    Candal, E.2
  • 89
    • 71549169901 scopus 로고    scopus 로고
    • Patterns of cell proliferation and rod photoreceptor differentiation in shark retinas
    • PID: 19822206
    • Ferreiro-Galve S, Rodríguez-Moldes I, Anadón R, Candal E (2010) Patterns of cell proliferation and rod photoreceptor differentiation in shark retinas. J Chem Neuroanat 39(1):1–14
    • (2010) J Chem Neuroanat , vol.39 , Issue.1 , pp. 1-14
    • Ferreiro-Galve, S.1    Rodríguez-Moldes, I.2    Anadón, R.3    Candal, E.4
  • 90
    • 84948087584 scopus 로고    scopus 로고
    • Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina
    • COI: 1:CAS:528:DC%2BC2MXhvFersb%2FJ, PID: 26053997
    • Todd L, Suarez L, Squires N, Zelinka CP, Gribbins K, Fischer AJ (2016) Comparative analysis of glucagonergic cells, glia, and the circumferential marginal zone in the reptilian retina. J Comp Neurol 524(1):74–89
    • (2016) J Comp Neurol , vol.524 , Issue.1 , pp. 74-89
    • Todd, L.1    Suarez, L.2    Squires, N.3    Zelinka, C.P.4    Gribbins, K.5    Fischer, A.J.6
  • 91
    • 0037204606 scopus 로고    scopus 로고
    • A comparative study of neurogenesis in the retinal ciliary marginal zone of homeothermic vertebrates
    • COI: 1:CAS:528:DC%2BD38Xis1OqtLs%3D, PID: 11947935
    • Kubota R, Hokoc JN, Moshiri A, McGuire C, Reh TA (2002) A comparative study of neurogenesis in the retinal ciliary marginal zone of homeothermic vertebrates. Brain Res Dev Brain Res 134(1–2):31–41
    • (2002) Brain Res Dev Brain Res , vol.134 , Issue.1-2 , pp. 31-41
    • Kubota, R.1    Hokoc, J.N.2    Moshiri, A.3    McGuire, C.4    Reh, T.A.5
  • 92
    • 0034656054 scopus 로고    scopus 로고
    • Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens
    • COI: 1:CAS:528:DC%2BD3cXit1Clt7w%3D, PID: 10753510
    • Fischer AJ, Reh TA (2000) Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens. Dev Biol 220(2):197–210
    • (2000) Dev Biol , vol.220 , Issue.2 , pp. 197-210
    • Fischer, A.J.1    Reh, T.A.2
  • 93
    • 84923365108 scopus 로고    scopus 로고
    • Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue
    • COI: 1:CAS:528:DC%2BC2MXosFems7o%3D, PID: 25695148, This study revealed the presence of a CMZ-like region human retinal tissue generated vitro
    • • Kuwahara A, Ozone C, Nakano T, Saito K, Eiraku M, Sasai Y (2015) Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue. Nat Commun 6:6286. This study revealed the presence of a CMZ-like region in human retinal tissue generated in vitro.
    • (2015) Nat Commun , vol.6 , pp. 6286
    • Kuwahara, A.1    Ozone, C.2    Nakano, T.3    Saito, K.4    Eiraku, M.5    Sasai, Y.6
  • 94
    • 80053969026 scopus 로고    scopus 로고
    • The rod photoreceptor lineage of teleost fish
    • COI: 1:CAS:528:DC%2BC3MXhtlejurrJ, PID: 21742053
    • Stenkamp DL (2011) The rod photoreceptor lineage of teleost fish. Prog Retin Eye Res 30(6):395–404
    • (2011) Prog Retin Eye Res , vol.30 , Issue.6 , pp. 395-404
    • Stenkamp, D.L.1
  • 95
    • 84899091763 scopus 로고    scopus 로고
    • Muller glia: stem cells for generation and regeneration of retinal neurons in teleost fish
    • PID: 24412518
    • Lenkowski JR, Raymond PA (2014) Muller glia: stem cells for generation and regeneration of retinal neurons in teleost fish. Prog Retin Eye Res 40:94–123
    • (2014) Prog Retin Eye Res , vol.40 , pp. 94-123
    • Lenkowski, J.R.1    Raymond, P.A.2
  • 96
    • 84906861192 scopus 로고    scopus 로고
    • Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina
    • COI: 1:CAS:528:DC%2BC2cXhvVWltr%2FE, PID: 25142461, This study revealed that retinal stem cells the CMZ preferentially divide asymmetrically both during tissue growth and during regeneration
    • • Centanin L, Ander JJ, Hoeckendorf B, Lust K, Kellner T, Kraemer I et al (2014) Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina. Development 141(18):3472–3482. This study revealed that retinal stem cells in the CMZ preferentially divide asymmetrically both during tissue growth and during regeneration.
    • (2014) Development , vol.141 , Issue.18 , pp. 3472-3482
    • Centanin, L.1    Ander, J.J.2    Hoeckendorf, B.3    Lust, K.4    Kellner, T.5    Kraemer, I.6
  • 97
    • 84978360335 scopus 로고    scopus 로고
    • The ciliary marginal zone of the zebrafish retina: clonal and time-lapse analysis of a continuously growing tissue
    • COI: 1:CAS:528:DC%2BC28XhsVKmtLrO, PID: 26893352, This time-lapse analysis showed that CMZ stem cells divide assymetrically a radial orientation to generate one stem cell that stays the peripheral niche and a progenitor that moves centrally and differentiates
    • • Wan Y, Almeida AD, Rulands S, Chalour N, Muresan L, Wu Y et al (2016) The ciliary marginal zone of the zebrafish retina: clonal and time-lapse analysis of a continuously growing tissue. Development 143(7):1099–1107. This time-lapse analysis showed that CMZ stem cells divide assymetrically in a radial orientation to generate one stem cell that stays in the peripheral niche and a progenitor that moves centrally and differentiates.
    • (2016) Development , vol.143 , Issue.7 , pp. 1099-1107
    • Wan, Y.1    Almeida, A.D.2    Rulands, S.3    Chalour, N.4    Muresan, L.5    Wu, Y.6
  • 98
    • 12544259712 scopus 로고    scopus 로고
    • Comparison of the expression patterns of five neural RNA binding proteins in the Xenopus retina
    • COI: 1:CAS:528:DC%2BD2MXnslWnug%3D%3D, PID: 15593335
    • Amato MA, Boy S, Arnault E, Girard M, Della Puppa A, Sharif A et al (2005) Comparison of the expression patterns of five neural RNA binding proteins in the Xenopus retina. J Comp Neurol 481(4):331–339
    • (2005) J Comp Neurol , vol.481 , Issue.4 , pp. 331-339
    • Amato, M.A.1    Boy, S.2    Arnault, E.3    Girard, M.4    Della Puppa, A.5    Sharif, A.6
  • 99
    • 70350214500 scopus 로고    scopus 로고
    • From progenitors to differentiated cells in the vertebrate retina
    • COI: 1:CAS:528:DC%2BD1MXhsVKisbrO, PID: 19575661
    • Agathocleous M, Harris WA (2009) From progenitors to differentiated cells in the vertebrate retina. Annu Rev Cell Dev Biol 25(1):45–69
    • (2009) Annu Rev Cell Dev Biol , vol.25 , Issue.1 , pp. 45-69
    • Agathocleous, M.1    Harris, W.A.2
  • 100
    • 0031800430 scopus 로고    scopus 로고
    • Molecular recapitulation: the growth of the vertebrate retina
    • COI: 1:CAS:528:DyaK1cXksFelsb0%3D, PID: 9654012
    • Harris WA, Perron M (1998) Molecular recapitulation: the growth of the vertebrate retina. Int J Dev Biol 42(3):299–304
    • (1998) Int J Dev Biol , vol.42 , Issue.3 , pp. 299-304
    • Harris, W.A.1    Perron, M.2
  • 101
    • 84870309974 scopus 로고    scopus 로고
    • Hes4 controls proliferative properties of neural stem cells during retinal ontogenesis
    • COI: 1:CAS:528:DC%2BC3sXptlemsw%3D%3D, PID: 22969013
    • El Yakoubi W, Borday C, Hamdache J, Parain K, Tran HT, Vleminckx K et al (2012) Hes4 controls proliferative properties of neural stem cells during retinal ontogenesis. Stem Cells 30(12):2784–2795
    • (2012) Stem Cells , vol.30 , Issue.12 , pp. 2784-2795
    • El Yakoubi, W.1    Borday, C.2    Hamdache, J.3    Parain, K.4    Tran, H.T.5    Vleminckx, K.6
  • 102
    • 84865856693 scopus 로고    scopus 로고
    • Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation
    • COI: 1:CAS:528:DC%2BC38Xhs1Ont7%2FJ, PID: 22899850
    • Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT et al (2012) Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation. Development 139(19):3499–3509
    • (2012) Development , vol.139 , Issue.19 , pp. 3499-3509
    • Borday, C.1    Cabochette, P.2    Parain, K.3    Mazurier, N.4    Janssens, S.5    Tran, H.T.6
  • 103
    • 17644375452 scopus 로고    scopus 로고
    • Genetic dissection of the zebrafish retinal stem-cell compartment
    • COI: 1:CAS:528:DC%2BD2MXjsFGqsrk%3D, PID: 15848388
    • Wehman AM, Staub W, Meyers JR, Raymond PA, Baier H (2005) Genetic dissection of the zebrafish retinal stem-cell compartment. Dev Biol 281(1):53–65
    • (2005) Dev Biol , vol.281 , Issue.1 , pp. 53-65
    • Wehman, A.M.1    Staub, W.2    Meyers, J.R.3    Raymond, P.A.4    Baier, H.5
  • 104
    • 84856962348 scopus 로고    scopus 로고
    • Continued growth and circuit building in the anamniote visual system
    • PID: 21563317
    • Cerveny KL, Varga M, Wilson SW (2012) Continued growth and circuit building in the anamniote visual system. Dev Neurobiol. 72(3):328–345
    • (2012) Dev Neurobiol. , vol.72 , Issue.3 , pp. 328-345
    • Cerveny, K.L.1    Varga, M.2    Wilson, S.W.3
  • 105
    • 19544389172 scopus 로고    scopus 로고
    • Genetic analysis of metamorphic and premetamorphic Xenopus ciliary marginal zone
    • COI: 1:CAS:528:DC%2BD2MXlsFeitLo%3D, PID: 15844194
    • Casarosa S, Leone P, Cannata S, Santini F, Pinchera A, Barsacchi G et al (2005) Genetic analysis of metamorphic and premetamorphic Xenopus ciliary marginal zone. Dev Dyn 233(2):646–651
    • (2005) Dev Dyn , vol.233 , Issue.2 , pp. 646-651
    • Casarosa, S.1    Leone, P.2    Cannata, S.3    Santini, F.4    Pinchera, A.5    Barsacchi, G.6
  • 106
    • 0036339911 scopus 로고    scopus 로고
    • Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina
    • COI: 1:CAS:528:DC%2BD38XksFWnurw%3D, PID: 11973275
    • Ohnuma S, Hopper S, Wang KC, Philpott A, Harris WA (2002) Co-ordinating retinal histogenesis: early cell cycle exit enhances early cell fate determination in the Xenopus retina. Development 129(10):2435–2446
    • (2002) Development , vol.129 , Issue.10 , pp. 2435-2446
    • Ohnuma, S.1    Hopper, S.2    Wang, K.C.3    Philpott, A.4    Harris, W.A.5
  • 107
    • 0018639367 scopus 로고
    • Regeneration of the goldfish retina after exposure to different doses of ouabain
    • COI: 1:STN:280:DyaL3c%2FmslWktA%3D%3D, PID: 509506
    • Maier W, Wolburg H (1979) Regeneration of the goldfish retina after exposure to different doses of ouabain. Cell Tissue Res 202(1):99–118
    • (1979) Cell Tissue Res , vol.202 , Issue.1 , pp. 99-118
    • Maier, W.1    Wolburg, H.2
  • 108
    • 0020265952 scopus 로고
    • Morphological study on the regeneration of the retina in the rainbow trout after ouabain-induced damage: evidence for dedifferentiation of photoreceptors
    • COI: 1:STN:280:DyaL3s%2FgtFylug%3D%3D, PID: 7116425
    • Kurz-Isler G, Wolburg H (1982) Morphological study on the regeneration of the retina in the rainbow trout after ouabain-induced damage: evidence for dedifferentiation of photoreceptors. Cell Tissue Res 225(1):165–178
    • (1982) Cell Tissue Res , vol.225 , Issue.1 , pp. 165-178
    • Kurz-Isler, G.1    Wolburg, H.2
  • 109
    • 0023335557 scopus 로고
    • Paradoxical induction of dopaminergic cells following intravitreal injection of high doses of 6-hydroxydopamine in juvenile carp retina
    • COI: 1:STN:280:DyaL2s3ktlKjtA%3D%3D, PID: 3109692
    • Negishi K, Teranishi T, Kato S, Nakamura Y (1987) Paradoxical induction of dopaminergic cells following intravitreal injection of high doses of 6-hydroxydopamine in juvenile carp retina. Brain Res 430(1):67–79
    • (1987) Brain Res , vol.430 , Issue.1 , pp. 67-79
    • Negishi, K.1    Teranishi, T.2    Kato, S.3    Nakamura, Y.4
  • 110
    • 0023876705 scopus 로고
    • Regeneration of goldfish retina: rod precursors are a likely source of regenerated cells
    • COI: 1:STN:280:DyaL1c3nsVeluw%3D%3D, PID: 3392530
    • Raymond PA, Reifler MJ, Rivlin PK (1988) Regeneration of goldfish retina: rod precursors are a likely source of regenerated cells. J Neurobiol 19(5):431–463
    • (1988) J Neurobiol , vol.19 , Issue.5 , pp. 431-463
    • Raymond, P.A.1    Reifler, M.J.2    Rivlin, P.K.3
  • 112
    • 0035911811 scopus 로고    scopus 로고
    • Evidence for two distinct mechanisms of neurogenesis and cellular pattern formation in regenerated goldfish retinas
    • COI: 1:STN:280:DC%2BD3M3jsVyjsw%3D%3D, PID: 11223808
    • Stenkamp DL, Powers MK, Carney LH, Cameron DA (2001) Evidence for two distinct mechanisms of neurogenesis and cellular pattern formation in regenerated goldfish retinas. J Comp Neurol 431(4):363–381
    • (2001) J Comp Neurol , vol.431 , Issue.4 , pp. 363-381
    • Stenkamp, D.L.1    Powers, M.K.2    Carney, L.H.3    Cameron, D.A.4
  • 113
    • 0020051701 scopus 로고
    • Formation of photoreceptors in larval and adult goldfish
    • COI: 1:STN:280:DyaL387ksVOmug%3D%3D, PID: 7062105
    • Johns PR (1982) Formation of photoreceptors in larval and adult goldfish. J Neurosci 2(2):178–198
    • (1982) J Neurosci , vol.2 , Issue.2 , pp. 178-198
    • Johns, P.R.1
  • 114
    • 0035313405 scopus 로고    scopus 로고
    • Putative stem cells and the lineage of rod photoreceptors in the mature retina of the goldfish
    • COI: 1:CAS:528:DC%2BD3MXhvFWgtbc%3D, PID: 11254348
    • Otteson DC, D’Costa AR, Hitchcock PF (2001) Putative stem cells and the lineage of rod photoreceptors in the mature retina of the goldfish. Dev Biol 232(1):62–76
    • (2001) Dev Biol , vol.232 , Issue.1 , pp. 62-76
    • Otteson, D.C.1    D’Costa, A.R.2    Hitchcock, P.F.3
  • 115
    • 84948800313 scopus 로고    scopus 로고
    • Tracking the fate of her4 expressing cells in the regenerating retina using her4:Kaede zebrafish
    • COI: 1:CAS:528:DC%2BC2MXhvFeqsLrI, PID: 26616101
    • Wilson SG, Wen W, Pillai-Kastoori L, Morris AC (2016) Tracking the fate of her4 expressing cells in the regenerating retina using her4:Kaede zebrafish. Exp Eye Res 145:75–87
    • (2016) Exp Eye Res , vol.145 , pp. 75-87
    • Wilson, S.G.1    Wen, W.2    Pillai-Kastoori, L.3    Morris, A.C.4
  • 116
    • 0023427620 scopus 로고
    • Cell-specific regulation of neuronal production in the larval frog retina
    • COI: 1:STN:280:DyaL1c%2FjsFWktg%3D%3D, PID: 3499488
    • Reh TA (1987) Cell-specific regulation of neuronal production in the larval frog retina. J Neurosci 7(10):3317–3324
    • (1987) J Neurosci , vol.7 , Issue.10 , pp. 3317-3324
    • Reh, T.A.1
  • 117
    • 84866251939 scopus 로고    scopus 로고
    • Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye
    • COI: 1:CAS:528:DC%2BC38XhsVSlsbnP, PID: 22973003
    • Kiyama T, Li H, Gupta M, Lin Y-P, Chuang AZ, Otteson DC et al (2012) Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye. J Neurosci 32(37):12797–12807
    • (2012) J Neurosci , vol.32 , Issue.37 , pp. 12797-12807
    • Kiyama, T.1    Li, H.2    Gupta, M.3    Lin, Y.-P.4    Chuang, A.Z.5    Otteson, D.C.6
  • 118
    • 84901608240 scopus 로고    scopus 로고
    • The retinal pigment epithelium: an important player of retinal disorders and regeneration
    • COI: 1:CAS:528:DC%2BC3sXht1Gmu7%2FM, PID: 23880527
    • Chiba C (2014) The retinal pigment epithelium: an important player of retinal disorders and regeneration. Exp Eye Res 123:107–114
    • (2014) Exp Eye Res , vol.123 , pp. 107-114
    • Chiba, C.1
  • 119
    • 11044239127 scopus 로고    scopus 로고
    • Retinal stem cells and regeneration
    • PID: 15558491
    • Moshiri A, Close J, Reh TA (2004) Retinal stem cells and regeneration. Int J Dev Biol. 48(8–9):1003–1014
    • (2004) Int J Dev Biol. , vol.48 , Issue.8-9 , pp. 1003-1014
    • Moshiri, A.1    Close, J.2    Reh, T.A.3
  • 120
    • 0000924215 scopus 로고
    • Regeneration of neural retina and lens from retina pigment cell grafts in adult newts
    • COI: 1:STN:280:DyaG1c%2Fitl2qsQ%3D%3D, PID: 13481298
    • Stone LS, Steinitz H (1957) Regeneration of neural retina and lens from retina pigment cell grafts in adult newts. J Exp Zool 135(2):301–317
    • (1957) J Exp Zool , vol.135 , Issue.2 , pp. 301-317
    • Stone, L.S.1    Steinitz, H.2
  • 121
    • 70949086261 scopus 로고    scopus 로고
    • Complete reconstruction of the retinal laminar structure from a cultured retinal pigment epithelium is triggered by altered tissue interaction and promoted by overlaid extracellular matrices
    • COI: 1:CAS:528:DC%2BC3cXjsl2msQ%3D%3D, PID: 19701886
    • Kuriyama F, Ueda Y, Araki M (2009) Complete reconstruction of the retinal laminar structure from a cultured retinal pigment epithelium is triggered by altered tissue interaction and promoted by overlaid extracellular matrices. Dev Neurobiol. 69(14):950–958
    • (2009) Dev Neurobiol. , vol.69 , Issue.14 , pp. 950-958
    • Kuriyama, F.1    Ueda, Y.2    Araki, M.3
  • 122
    • 84855517118 scopus 로고    scopus 로고
    • Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives
    • COI: 1:CAS:528:DC%2BC38XltVWksw%3D%3D, PID: 22226358
    • Salero E, Blenkinsop TA, Corneo B, Harris A, Rabin D, Stern JH et al (2012) Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives. Cell Stem Cell 10(1):88–95
    • (2012) Cell Stem Cell , vol.10 , Issue.1 , pp. 88-95
    • Salero, E.1    Blenkinsop, T.A.2    Corneo, B.3    Harris, A.4    Rabin, D.5    Stern, J.H.6
  • 123
    • 84929652919 scopus 로고    scopus 로고
    • Glucose, lactate, and shuttling of metabolites in vertebrate retinas
    • COI: 1:CAS:528:DC%2BC2MXkvVaiu7Y%3D, PID: 25801286
    • Hurley JB, Lindsay KJ, Du J (2015) Glucose, lactate, and shuttling of metabolites in vertebrate retinas. J Neurosci Res 93(7):1079–1092
    • (2015) J Neurosci Res , vol.93 , Issue.7 , pp. 1079-1092
    • Hurley, J.B.1    Lindsay, K.J.2    Du, J.3
  • 124
    • 33745626845 scopus 로고    scopus 로고
    • A role for 1 tubulin-expressing Muller glia in regeneration of the injured zebrafish retina
    • COI: 1:CAS:528:DC%2BD28XmtFSlsbo%3D, PID: 16763038
    • Fausett BV, Goldman D (2006) A role for 1 tubulin-expressing Muller glia in regeneration of the injured zebrafish retina. J Neurosci 26(23):6303–6313
    • (2006) J Neurosci , vol.26 , Issue.23 , pp. 6303-6313
    • Fausett, B.V.1    Goldman, D.2
  • 125
    • 38749090553 scopus 로고    scopus 로고
    • The proneural basic helix-loop-helix gene ascl1a is required for retina regeneration
    • COI: 1:CAS:528:DC%2BD1cXhvVSksLs%3D, PID: 18234889
    • Fausett BV, Gumerson JD, Goldman D (2008) The proneural basic helix-loop-helix gene ascl1a is required for retina regeneration. J Neurosci 28(5):1109–1117
    • (2008) J Neurosci , vol.28 , Issue.5 , pp. 1109-1117
    • Fausett, B.V.1    Gumerson, J.D.2    Goldman, D.3
  • 126
    • 39349115517 scopus 로고    scopus 로고
    • Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina
    • PID: 18161852
    • Thummel R, Kassen SC, Montgomery JE, Enright JM, Hyde DR (2008) Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina. Dev Neurobiol 68(3):392–408
    • (2008) Dev Neurobiol , vol.68 , Issue.3 , pp. 392-408
    • Thummel, R.1    Kassen, S.C.2    Montgomery, J.E.3    Enright, J.M.4    Hyde, D.R.5
  • 127
    • 54249151789 scopus 로고    scopus 로고
    • Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration
    • COI: 1:CAS:528:DC%2BD1cXht12rsbjI, PID: 18718467
    • Thummel R, Kassen SC, Enright JM, Nelson CM, Montgomery JE, Hyde DR (2008) Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration. Exp Eye Res 87(5):433–444
    • (2008) Exp Eye Res , vol.87 , Issue.5 , pp. 433-444
    • Thummel, R.1    Kassen, S.C.2    Enright, J.M.3    Nelson, C.M.4    Montgomery, J.E.5    Hyde, D.R.6
  • 128
    • 84943339773 scopus 로고    scopus 로고
    • Cell fate of Müller cells during photoreceptor regeneration in an N-nethyl-N-nitrosourea-induced retinal degeneration model of zebrafish
    • (,),. In
    • Ogai K, Hisano S, Sugitani K, Koriyama Y, Kato S (2016) Cell fate of Müller cells during photoreceptor regeneration in an N-nethyl-N-nitrosourea-induced retinal degeneration model of zebrafish. In: Advances in experimental medicine and biology, pp. 685–692
    • (2016) Advances in experimental medicine and biology , pp. 685-692
    • Ogai, K.1    Hisano, S.2    Sugitani, K.3    Koriyama, Y.4    Kato, S.5
  • 129
    • 84855914219 scopus 로고    scopus 로고
    • Müllerglia as a source of neuronal progenitor cells to regenerate the damaged zebrafish retina
    • Nelson CM, Hyde DR (2012) Müllerglia as a source of neuronal progenitor cells to regenerate the damaged zebrafish retina. Adv Exp Med Biol 723:425–430
    • (2012) Adv Exp Med Biol , vol.723 , pp. 425-430
    • Nelson, C.M.1    Hyde, D.R.2
  • 131
    • 84901608385 scopus 로고    scopus 로고
    • Regulation of Müller glial dependent neuronal regeneration in the damaged adult zebrafish retina
    • COI: 1:CAS:528:DC%2BC3sXht1WrsrnK, PID: 23880528
    • Gorsuch RA, Hyde DR (2014) Regulation of Müller glial dependent neuronal regeneration in the damaged adult zebrafish retina. Exp Eye Res 123:131–140
    • (2014) Exp Eye Res , vol.123 , pp. 131-140
    • Gorsuch, R.A.1    Hyde, D.R.2
  • 132
    • 84975126815 scopus 로고    scopus 로고
    • Müller glial cell-dependent regeneration of the neural retina: an overview across vertebrate model systems
    • PID: 26661417
    • Hamon A, Roger JE, Yang X-J, Perron M (2016) Müller glial cell-dependent regeneration of the neural retina: an overview across vertebrate model systems. Dev Dyn 245(7):727–738
    • (2016) Dev Dyn , vol.245 , Issue.7 , pp. 727-738
    • Hamon, A.1    Roger, J.E.2    Yang, X.-J.3    Perron, M.4
  • 133
    • 84998865522 scopus 로고    scopus 로고
    • Müller stem cell dependent retinal regeneration
    • COI: 1:CAS:528:DC%2BC28XhvFGgurrO, PID: 27876464
    • Chohan A, Singh U, Kumar A, Kaur J (2017) Müller stem cell dependent retinal regeneration. Clin Chim Acta 464:160–164
    • (2017) Clin Chim Acta , vol.464 , pp. 160-164
    • Chohan, A.1    Singh, U.2    Kumar, A.3    Kaur, J.4
  • 134
    • 84904464798 scopus 로고    scopus 로고
    • Retinal regeneration is facilitated by the presence of surviving neurons
    • COI: 1:CAS:528:DC%2BC2cXhtFKltrzF, PID: 24488694
    • Sherpa T, Lankford T, McGinn TE, Hunter SS, Frey RA, Sun C et al (2014) Retinal regeneration is facilitated by the presence of surviving neurons. Dev Neurobiol 74(9):851–876
    • (2014) Dev Neurobiol , vol.74 , Issue.9 , pp. 851-876
    • Sherpa, T.1    Lankford, T.2    McGinn, T.E.3    Hunter, S.S.4    Frey, R.A.5    Sun, C.6
  • 135
    • 84943338962 scopus 로고    scopus 로고
    • Interkinetic nuclear migration in the regenerating retina
    • PID: 26427463
    • Lahne M, Hyde DR (2016) Interkinetic nuclear migration in the regenerating retina. Adv Exp Med Biol 854:587–593
    • (2016) Adv Exp Med Biol , vol.854 , pp. 587-593
    • Lahne, M.1    Hyde, D.R.2
  • 136
    • 84887164189 scopus 로고    scopus 로고
    • A self-renewing division of zebrafish Muller glial cells generates neuronal progenitors that require N-cadherin to regenerate retinal neurons
    • COI: 1:CAS:528:DC%2BC3sXhvFyntb3M, PID: 24154521
    • Nagashima M, Barthel LK, Raymond PA (2013) A self-renewing division of zebrafish Muller glial cells generates neuronal progenitors that require N-cadherin to regenerate retinal neurons. Development 140(22):4510–4521
    • (2013) Development , vol.140 , Issue.22 , pp. 4510-4521
    • Nagashima, M.1    Barthel, L.K.2    Raymond, P.A.3
  • 137
    • 84948142766 scopus 로고    scopus 로고
    • Actin-cytoskeleton- and rock-mediated INM are required for photoreceptor regeneration in the adult zebrafish retina
    • COI: 1:CAS:528:DC%2BC28XhtFOntrzK, PID: 26609156, This study sheds light on the mechanism of interkinetic migration of Müller cells and Müller cell-derived progenitors during regeneration
    • • Lahne M, Li J, Marton RM, Hyde DR (2015) Actin-cytoskeleton- and rock-mediated INM are required for photoreceptor regeneration in the adult zebrafish retina. J Neurosci 35(47):15612–15634. This study sheds light on the mechanism of interkinetic migration of Müller cells and Müller cell-derived progenitors during regeneration.
    • (2015) J Neurosci , vol.35 , Issue.47 , pp. 15612-15634
    • Lahne, M.1    Li, J.2    Marton, R.M.3    Hyde, D.R.4
  • 139
    • 84948783777 scopus 로고    scopus 로고
    • Reactive gliosis in the adult zebrafish retina
    • COI: 1:CAS:528:DC%2BC2MXhslGmtb3M, PID: 26492821
    • Thomas JL, Ranski AH, Morgan GW, Thummel R (2016) Reactive gliosis in the adult zebrafish retina. Exp Eye Res 143:98–109
    • (2016) Exp Eye Res , vol.143 , pp. 98-109
    • Thomas, J.L.1    Ranski, A.H.2    Morgan, G.W.3    Thummel, R.4
  • 140
    • 84875969209 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha is produced by dying retinal neurons and is required for Muller glia proliferation during zebrafish retinal regeneration
    • COI: 1:CAS:528:DC%2BC3sXhtl2jtrbM, PID: 23575850
    • Nelson CM, Ackerman KM, O’Hayer P, Bailey TJ, Gorsuch RA, Hyde DR (2013) Tumor necrosis factor-alpha is produced by dying retinal neurons and is required for Muller glia proliferation during zebrafish retinal regeneration. J Neurosci 33(15):6524–6539
    • (2013) J Neurosci , vol.33 , Issue.15 , pp. 6524-6539
    • Nelson, C.M.1    Ackerman, K.M.2    O’Hayer, P.3    Bailey, T.J.4    Gorsuch, R.A.5    Hyde, D.R.6
  • 141
    • 78149285528 scopus 로고    scopus 로고
    • Ascl1a regulates Muller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway
    • COI: 1:CAS:528:DC%2BC3cXhtlKgs7nK, PID: 20935637
    • Ramachandran R, Fausett BV, Goldman D (2010) Ascl1a regulates Muller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nat Cell Biol 12(11):1101–1107
    • (2010) Nat Cell Biol , vol.12 , Issue.11 , pp. 1101-1107
    • Ramachandran, R.1    Fausett, B.V.2    Goldman, D.3
  • 142
    • 84990242083 scopus 로고    scopus 로고
    • Rapid, dynamic activation of Müller glial stem cell responses in zebrafish
    • COI: 1:CAS:528:DC%2BC28XitFequ7zK
    • Sifuentes CJ, Kim J-W, Swaroop A, Raymond PA (2016) Rapid, dynamic activation of Müller glial stem cell responses in zebrafish. Investig Opthalmology Vis Sci 57(13):5148
    • (2016) Investig Opthalmology Vis Sci , vol.57 , Issue.13 , pp. 5148
    • Sifuentes, C.J.1    Kim, J.-W.2    Swaroop, A.3    Raymond, P.A.4
  • 143
    • 84907966911 scopus 로고    scopus 로고
    • Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration
    • COI: 1:CAS:528:DC%2BC2cXhs1agt7jP, PID: 25263555, This study provides important insights into cross talk between growth factors and cytokine signaling required for Müller cell proliferation response to retinal injury
    • • Wan J, Zhao X-F, Vojtek A, Goldman D (2014) Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration. Cell Rep 9(1):285–297. This study provides important insights into cross talk between growth factors and cytokine signaling required for Müller cell proliferation in response to retinal injury.
    • (2014) Cell Rep , vol.9 , Issue.1 , pp. 285-297
    • Wan, J.1    Zhao, X.-F.2    Vojtek, A.3    Goldman, D.4
  • 144
    • 84973649741 scopus 로고    scopus 로고
    • Retina regeneration in zebrafish
    • COI: 1:CAS:528:DC%2BC28XptVCktrY%3D, PID: 27281280
    • Wan J, Goldman D (2016) Retina regeneration in zebrafish. Curr Opin Genet Dev 40:41–47
    • (2016) Curr Opin Genet Dev , vol.40 , pp. 41-47
    • Wan, J.1    Goldman, D.2
  • 145
    • 84996564411 scopus 로고    scopus 로고
    • Inhibition of the TGFβ pathway enhances retinal regeneration in adult zebrafish. Thummel R
    • (,), editor
    • Tappeiner C, Maurer E, Sallin P, Bise T, Enzmann V, Tschopp M (2016) Inhibition of the TGFβ pathway enhances retinal regeneration in adult zebrafish. Thummel R, editor. PLoS One 11(11):e0167073
    • (2016) PLoS One , vol.11 , Issue.11
    • Tappeiner, C.1    Maurer, E.2    Sallin, P.3    Bise, T.4    Enzmann, V.5    Tschopp, M.6
  • 146
    • 84867097798 scopus 로고    scopus 로고
    • Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina
    • COI: 1:CAS:528:DC%2BC38XhtlymurrP, PID: 23000964
    • Ramachandran R, Zhao X-F, Goldman D (2012) Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina. Nat Cell Biol 14(10):1013–1023
    • (2012) Nat Cell Biol , vol.14 , Issue.10 , pp. 1013-1023
    • Ramachandran, R.1    Zhao, X.-F.2    Goldman, D.3
  • 147
    • 84946594596 scopus 로고    scopus 로고
    • Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice
    • COI: 1:CAS:528:DC%2BC2MXhs1yksbbM, PID: 26483457
    • Ueki Y, Wilken MS, Cox KE, Chipman L, Jorstad N, Sternhagen K et al (2015) Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice. Proc Natl Acad Sci 112(44):13717–13722
    • (2015) Proc Natl Acad Sci , vol.112 , Issue.44 , pp. 13717-13722
    • Ueki, Y.1    Wilken, M.S.2    Cox, K.E.3    Chipman, L.4    Jorstad, N.5    Sternhagen, K.6
  • 148
    • 84973558763 scopus 로고    scopus 로고
    • De novo neurogenesis by targeted expression of atoh7 to Müller glia cells
    • COI: 1:CAS:528:DC%2BC28Xhs1GitrvL, PID: 27068106
    • Lust K, Sinn R, Pérez Saturnino A, Centanin L, Wittbrodt J (2016) De novo neurogenesis by targeted expression of atoh7 to Müller glia cells. Development 143(11):1874–1883
    • (2016) Development , vol.143 , Issue.11 , pp. 1874-1883
    • Lust, K.1    Sinn, R.2    Pérez Saturnino, A.3    Centanin, L.4    Wittbrodt, J.5
  • 149
    • 84981724839 scopus 로고    scopus 로고
    • Mismatch of synaptic patterns between neurons produced in regeneration and during development of the vertebrate retina
    • PID: 27524481, COI: 1:CAS:528:DC%2BC28XhtleisrfI, This study revealed that the synaptic connections of cells lost following degeneration are not always reestablished after regeneration
    • • D’Orazi FD, Zhao X-F, Wong RO, Yoshimatsu T (2016) Mismatch of synaptic patterns between neurons produced in regeneration and during development of the vertebrate retina. Curr Biol 26(17):2268–2279. This study revealed that the synaptic connections of cells lost following degeneration are not always reestablished after regeneration.
    • (2016) Curr Biol , vol.26 , Issue.17 , pp. 2268-2279
    • D’Orazi, F.D.1    Zhao, X.-F.2    Wong, R.O.3    Yoshimatsu, T.4
  • 150
    • 84995906268 scopus 로고    scopus 로고
    • Regeneration: new neurons wire up
    • COI: 1:CAS:528:DC%2BC28XhsFars7rI, PID: 27623258
    • Raymond PA (2016) Regeneration: new neurons wire up. Curr Biol 26(17):R794–R796
    • (2016) Curr Biol , vol.26 , Issue.17 , pp. R794-R796
    • Raymond, P.A.1
  • 151
    • 84900874512 scopus 로고    scopus 로고
    • Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells
    • COI: 1:CAS:528:DC%2BC2cXitVaksLzJ, PID: 24832361
    • Yoshimatsu T, Williams PR, D’Orazi FD, Suzuki SC, Fadool JM, Allison WT et al (2014) Transmission from the dominant input shapes the stereotypic ratio of photoreceptor inputs onto horizontal cells. Nat Commun 5:3699
    • (2014) Nat Commun , vol.5 , pp. 3699
    • Yoshimatsu, T.1    Williams, P.R.2    D’Orazi, F.D.3    Suzuki, S.C.4    Fadool, J.M.5    Allison, W.T.6
  • 152
    • 79952261758 scopus 로고    scopus 로고
    • Cone degeneration following rod ablation in a reversible model of retinal degeneration
    • COI: 1:CAS:528:DC%2BC3MXmsVShtb0%3D, PID: 20720220
    • Choi RY, Engbretson GA, Solessio EC, Jones GA, Coughlin A, Aleksic I et al (2011) Cone degeneration following rod ablation in a reversible model of retinal degeneration. Invest Ophthalmol Vis Sci 52(1):364–373
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , Issue.1 , pp. 364-373
    • Choi, R.Y.1    Engbretson, G.A.2    Solessio, E.C.3    Jones, G.A.4    Coughlin, A.5    Aleksic, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.