Transplantation of human embryonic stem cell-derived retinal tissue in two primate models of retinal degeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 1, 2016, Pages E81-E90

  Shirai, Hiroshi ^a,b   Mandai, Michiko ^a   Matsushita, Keizo ^a,c   Kuwahara, Atsushi ^a,c,d   Yonemura, Shigenobu ^a   Nakano, Tokushige ^a,d   Assawachananont, Juthaporn ^a   Kimura, Toru ^c   Saito, Koichi ^d   Terasaki, Hiroko ^b   Eirakug, Mototsugu ^a   Sasai, Yoshiki ^a   Takahashi, Masayo ^a  

^a RIKEN Center for Biosystems Dynamics Research   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^d SUMITOMO CHEMICAL CO LTD   (Japan)

Author keywords

Human embryonic stem cells; Photoreceptors; Primate model; Retinal degeneration; Transplantation

Indexed keywords

COBALT CHLORIDE; COBALT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTRORETINOGRAM; HUMAN EMBRYONIC STEM CELL; IMMUNOHISTOCHEMISTRY; LASER COAGULATION; NONHUMAN; PHOTORECEPTOR; PLURIPOTENT STEM CELL; PRIMATE MODEL; PRIORITY JOURNAL; RETINA DEGENERATION; RETINAL TISSUE; RETINITIS PIGMENTOSA; STEM CELL TRANSPLANTATION; SYNAPTOGENESIS; VISUAL ACUITY; ANIMAL; CELL DIFFERENTIATION; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; HAPLORHINI; HUMAN; PATHOLOGY; PHOTORECEPTOR CELL; PRIMATE; RAT; RETINA; RETINAL DEGENERATION; TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; COBALT; DISEASE MODELS, ANIMAL; HAPLORHINI; HUMAN EMBRYONIC STEM CELLS; HUMANS; PHOTORECEPTOR CELLS; PRIMATES; RATS; RETINA; RETINAL DEGENERATION;

EID: 84953253310     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1512590113     Document Type: Article

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