메뉴 건너뛰기




Volumn 25, Issue 7, 2010, Pages 933-944

Animal models for retinitis pigmentosa induced by MNU; disease progression, mechanisms and therapeutic trials

Author keywords

Apoptosis; Caspase; N methyl Nnitrosourea (MNU); Poly (ADP ribose) polymerase (PARP); Retinitis pigmentosa

Indexed keywords

ANIMALIA;

EID: 77956624063     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (89)

References (67)
  • 2
    • 0037442006 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts
    • Andreone T.L., O'Connor M., Denenberg A., Hake P.W. and Zingarelli B. (2003). Poly(ADP-ribose) polymerase-1 regulates activation of activator protein-1 in murine fibroblasts. J. Immunol. 170, 2113-2120.
    • (2003) J. Immunol. , vol.170 , pp. 2113-2120
    • Andreone, T.L.1    O'Connor, M.2    Denenberg, A.3    Hake, P.W.4    Zingarelli, B.5
  • 3
    • 0022492499 scopus 로고
    • DNA strand breaks, NAD metabolism, and programmed cell death
    • Carson D.A., Seto S., Wasson D.B. and Carrera C.J. (1986). DNA strand breaks, NAD metabolism, and programmed cell death. Exp. Cell Res. 164, 273-281.
    • (1986) Exp. Cell Res. , vol.164 , pp. 273-281
    • Carson, D.A.1    Seto, S.2    Wasson, D.B.3    Carrera, C.J.4
  • 4
    • 0027521914 scopus 로고
    • Apoptosis: Final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
    • Chang G.Q., Hao Y. and Wong F. (1993). Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 11, 595-605.
    • (1993) Neuron , vol.11 , pp. 595-605
    • Chang, G.Q.1    Hao, Y.2    Wong, F.3
  • 5
    • 0036499892 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase: Killer or conspirator? The 'suicide hypothesis' revisited
    • Chiarugi A. (2002). Poly(ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited. Trends Pharmacol. Sci. 23, 22-29.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 22-29
    • Chiarugi, A.1
  • 6
    • 0032500713 scopus 로고    scopus 로고
    • Systemic administration of acidic fibroblast growth factor ameliorates the ischemic injury of the retina in rats
    • Cuevas P., Carceller F., Redondo-Horcajo M., Lozano R.M. and Giménez-Gallego G. (1998). Systemic administration of acidic fibroblast growth factor ameliorates the ischemic injury of the retina in rats. Neurosci. Lett. 255, 1-4.
    • (1998) Neurosci. Lett. , vol.255 , pp. 1-4
    • Cuevas, P.1    Carceller, F.2    Redondo-Horcajo, M.3    Lozano, R.M.4    Giménez-Gallego, G.5
  • 7
    • 27444437192 scopus 로고    scopus 로고
    • Mouse mutants as models for congenital retinal disorders
    • Dalke C. and Graw J. (2005). Mouse mutants as models for congenital retinal disorders. Exp. Eye Res. 81, 503-512.
    • (2005) Exp. Eye Res. , vol.81 , pp. 503-512
    • Dalke, C.1    Graw, J.2
  • 8
    • 0023821554 scopus 로고
    • Antibodies against 7-methyldeoxyguanosine: Its detection in rat peripheral blood lymphocyte DNA and potential applications to molecular epidemiology
    • Degan P., Montesano R. and Wild C.P. (1988). Antibodies against 7-methyldeoxyguanosine: its detection in rat peripheral blood lymphocyte DNA and potential applications to molecular epidemiology. Cancer Res. 48, 5065-5070.
    • (1988) Cancer Res. , vol.48 , pp. 5065-5070
    • Degan, P.1    Montesano, R.2    Wild, C.P.3
  • 9
    • 51249193841 scopus 로고
    • Beitra ge zur pathologischen anatomie des auges. Albrecht von graefes arch
    • in German
    • Donders F.C. (1857). Beitra ge zur pathologischen Anatomie des Auges. Albrecht von Graefes Arch. Ophtalmol. 3, 139-165 [in German].
    • (1857) Ophtalmol , vol.3 , pp. 139-165
    • Donders, F.C.1
  • 10
    • 32944467645 scopus 로고    scopus 로고
    • Activation of multiple pathways during photoreceptor apoptosis in the rd mouse
    • Doonan F., Donovan M. and Cotter T.G. (2005). Activation of multiple pathways during photoreceptor apoptosis in the rd mouse. Invest. Ophthalmol. Vis. Sci. 46, 3530-3538.
    • (2005) Invest. Ophthalmol. Vis. Sci. , vol.46 , pp. 3530-3538
    • Doonan, F.1    Donovan, M.2    Cotter, T.G.3
  • 11
    • 0027946686 scopus 로고
    • Altered gene expression in neurons during programmed cell death: Identification of c-jun as necessary for neuronal apoptosis
    • Estus S., Zaks W.J., Freeman R.S., Gruda M., Bravo R. and Johnson E.M. Jr. (1994). Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. J. Cell Biol. 127, 1717-1727.
    • (1994) J. Cell Biol. , vol.127 , pp. 1717-1727
    • Estus, S.1    Zaks, W.J.2    Freeman, R.S.3    Gruda, M.4    Bravo, R.5    Johnson Jr., E.M.6
  • 12
  • 14
    • 0034908348 scopus 로고    scopus 로고
    • AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun
    • Grimm C., Wenzel A., Behrens A., Hafezi F., Wagner E.F. and Remé C.E. (2001). AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun. Cell Death Differ. 8, 859-867.
    • (2001) Cell Death Differ. , vol.8 , pp. 859-867
    • Grimm, C.1    Wenzel, A.2    Behrens, A.3    Hafezi, F.4    Wagner, E.F.5    Remé, C.E.6
  • 16
    • 0014145833 scopus 로고
    • Pigmentary degeneration of the retina induced by N-methyl-N-nitrosourea. An experimental study in Syrian hamsters
    • Herrold K.M. (1967). Pigmentary degeneration of the retina induced by N-methyl-N-nitrosourea. An experimental study in Syrian hamsters. Arch. Ophthalmol. 78, 650-653.
    • (1967) Arch. Ophthalmol. , vol.78 , pp. 650-653
    • Herrold, K.M.1
  • 17
    • 0001477027 scopus 로고
    • The effect of niacinamide on cerebral circulation
    • Huang T.F. and Chao C.C. (1960). The effect of niacinamide on cerebral circulation. Proc. Soc. Exp. Biol. Med. 105, 551-553.
    • (1960) Proc. Soc. Exp. Biol. Med. , vol.105 , pp. 551-553
    • Huang, T.F.1    Chao, C.C.2
  • 19
    • 0036353980 scopus 로고    scopus 로고
    • Nicotinamide prevents N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats and C57BL mice
    • Kiuchi K., Yoshizawa K., Shikata N., Matsumura M. and Tsubura A. (2002). Nicotinamide prevents N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats and C57BL mice. Exp. Eye Res. 74, 383-392.
    • (2002) Exp. Eye Res. , vol.74 , pp. 383-392
    • Kiuchi, K.1    Yoshizawa, K.2    Shikata, N.3    Matsumura, M.4    Tsubura, A.5
  • 21
    • 0033524924 scopus 로고    scopus 로고
    • Photooxidative stress down-modulates the activity of nuclear factor-kappa B via involvement of caspase-1, leading to apoptosis of photoreceptor cells
    • Krishnamoorthy R.R., Crawford M.J., Chaturvedi M.M., Jain S.K., Aggarwal B.B., Al-Ubaidi M.R. and Agarwal N. (1999). Photooxidative stress down-modulates the activity of nuclear factor-kappa B via involvement of caspase-1, leading to apoptosis of photoreceptor cells. J. Biol. Chem. 274, 3734-3743.
    • (1999) J. Biol. Chem. , vol.274 , pp. 3734-3743
    • Krishnamoorthy, R.R.1    Crawford, M.J.2    Chaturvedi, M.M.3    Jain, S.K.4    Aggarwal, B.B.5    Al-Ubaidi, M.R.6    Agarwal, N.7
  • 22
    • 47249118783 scopus 로고    scopus 로고
    • Intravitreal injection of fluorochrome-conjugated peanut agglutinin results in specific and reversible labeling of mammalian cones in vivo
    • Krishnamoorthy V., Jain V., Cherukuri P., Baloni S. and Dhingra N.K. (2008). Intravitreal injection of fluorochrome-conjugated peanut agglutinin results in specific and reversible labeling of mammalian cones in vivo. Invest. Ophthalmol. Vis. Sci. 49, 2643-2660.
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 2643-2660
    • Krishnamoorthy, V.1    Jain, V.2    Cherukuri, P.3    Baloni, S.4    Dhingra, N.K.5
  • 23
    • 77957271346 scopus 로고    scopus 로고
    • Study of mechanism of retinal damage by N-methyl-Nnitrosourea
    • In Japanese, Abstract in English
    • Maruyama I., Ohguro H., Maeda T., Takano Y. and Nakazawa M. (2001) Study of mechanism of retinal damage by N-methyl-Nnitrosourea. J. Eye 18, 539-542 [In Japanese, Abstract in English].
    • (2001) J. Eye , vol.18 , pp. 539-542
    • Maruyama, I.1    Ohguro, H.2    Maeda, T.3    Takano, Y.4    Nakazawa, M.5
  • 24
    • 33845648603 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamid rescues N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity
    • Miki K., Uehara N., Shikata N., Matsumura M. and Tsubura A. (2007). Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamid rescues N-methyl-N- nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity. Exp. Eye Res. 84, 285-292.
    • (2007) Exp. Eye Res. , vol.84 , pp. 285-292
    • Miki, K.1    Uehara, N.2    Shikata, N.3    Matsumura, M.4    Tsubura, A.5
  • 25
    • 1842561700 scopus 로고    scopus 로고
    • Suppression of N-methyl-N-nitrosoureainduced photoreceptor apoptosis in rats by docosahexaenoic acid
    • Moriguchi K., Yoshizawa K., Shikata N., Yuri T., Takada H., Hada T. and Tsubura A. (2004). Suppression of N-methyl-N-nitrosoureainduced photoreceptor apoptosis in rats by docosahexaenoic acid. Ophthalmic Res. 36, 98-105.
    • (2004) Ophthalmic Res. , vol.36 , pp. 98-105
    • Moriguchi, K.1    Yoshizawa, K.2    Shikata, N.3    Yuri, T.4    Takada, H.5    Hada, T.6    Tsubura, A.7
  • 27
    • 0029908025 scopus 로고    scopus 로고
    • Pigmentary degeneration induced by N-methyl-Nnitrosourea and the fate of pigment epithelial cells in the rat retina
    • Nakajima M., Nambu H., Shikata N., Senzaki H., Miki H. and Tsubura A. (1996a). Pigmentary degeneration induced by N-methyl-Nnitrosourea and the fate of pigment epithelial cells in the rat retina. Pathol. Int. 46, 874-882.
    • (1996) Pathol. Int. , vol.46 , pp. 874-882
    • Nakajima, M.1    Nambu, H.2    Shikata, N.3    Senzaki, H.4    Miki, H.5    Tsubura, A.6
  • 28
    • 0030022206 scopus 로고    scopus 로고
    • Photoreceptor apoptosis induced by a single systemic administration of N-methyl-N-nitrosourea in the rat retina
    • Nakajima M., Yuge K., Senzaki H., Shikata N., Miki H., Uyama M. and Tsubura A. (1996b). Photoreceptor apoptosis induced by a single systemic administration of N-methyl-N-nitrosourea in the rat retina. Am. J. Pathol. 148, 631-641.
    • (1996) Am. J. Pathol. , vol.148 , pp. 631-641
    • Nakajima, M.1    Yuge, K.2    Senzaki, H.3    Shikata, N.4    Miki, H.5    Uyama, M.6    Tsubura, A.7
  • 29
    • 0031948178 scopus 로고    scopus 로고
    • Timespecific action of N-methyl-N-nitrosourea in the occurrence of retinal dysplasia and retinal degeneration in neonatal mice
    • Nambu H., Taomoto M., Ogura E. and Tsubura A. (1998a). Timespecific action of N-methyl-N-nitrosourea in the occurrence of retinal dysplasia and retinal degeneration in neonatal mice. Pathol. Int. 48, 199-205.
    • (1998) Pathol. Int. , vol.48 , pp. 199-205
    • Nambu, H.1    Taomoto, M.2    Ogura, E.3    Tsubura, A.4
  • 30
    • 54649083035 scopus 로고    scopus 로고
    • Age-specific and dose-dependent retinal dysplasia and degeneration induced by a single intraperitoneal administration of Nmethyl-N-nitrosourea to rats
    • Nambu H., Yoshizawa K., Yang J., Yamamoto D. and Tsubura A. (1998b). Age-specific and dose-dependent retinal dysplasia and degeneration induced by a single intraperitoneal administration of Nmethyl-N-nitrosourea to rats. J. Toxicol. Pathol. 11, 127-131.
    • (1998) J. Toxicol. Pathol. , vol.11 , pp. 127-131
    • Nambu, H.1    Yoshizawa, K.2    Yang, J.3    Yamamoto, D.4    Tsubura, A.5
  • 31
    • 0030253312 scopus 로고    scopus 로고
    • Fas-independent apopatosis of photoreceptor cells in C3H mice
    • Nambu H., Yuge K., Shikata N., Tsubura A. and Matsuzawa A. (1996). Fas-independent apopatosis of photoreceptor cells in C3H mice. Exp. Anim. 45, 309-315.
    • (1996) Exp. Anim. , vol.45 , pp. 309-315
    • Nambu, H.1    Yuge, K.2    Shikata, N.3    Tsubura, A.4    Matsuzawa, A.5
  • 32
    • 0027178816 scopus 로고
    • Retinal degeneration induced by Nmethyl-N-nitrosourea and detection of 7-methyldeoxyguanosine in the rat retina
    • Ogino H., Ito M., Matsumoto K., Yagyu S., Tsuda H., Hirono I., Wild CP. and Montesano R. (1993). Retinal degeneration induced by Nmethyl-N-nitrosourea and detection of 7-methyldeoxyguanosine in the rat retina. Toxicol. Pathol. 21, 21-25.
    • (1993) Toxicol. Pathol. , vol.21 , pp. 21-25
    • Ogino, H.1    Ito, M.2    Matsumoto, K.3    Yagyu, S.4    Tsuda, H.5    Hirono, I.6    Wild, C.P.7    Montesano, R.8
  • 33
    • 33847384203 scopus 로고    scopus 로고
    • Contribution of calpains to photoreceptor cell death in N-methyl-Nnitrosourea-treated rats
    • Oka T., Nakajima T., Tamada Y., Shearer T.R. and Azuma M. (2007). Contribution of calpains to photoreceptor cell death in N-methyl-Nnitrosourea- treated rats. Exp. Neurol. 204, 39-48.
    • (2007) Exp. Neurol. , vol.204 , pp. 39-48
    • Oka, T.1    Nakajima, T.2    Tamada, Y.3    Shearer, T.R.4    Azuma, M.5
  • 34
    • 34548847441 scopus 로고    scopus 로고
    • Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse
    • Paquet-Durand F., Silva J., Talukdar T., Johnson L.E., Azadi S., van Veen T., Ueffing M., Hauck S.M. and Ekström P.A. (2007). Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. J. Neurosci. 19, 10311-10319.
    • (2007) J. Neurosci. , vol.19 , pp. 10311-10319
    • Paquet-Durand, F.1    Silva, J.2    Talukdar, T.3    Johnson, L.E.4    Azadi, S.5    Van Veen, T.6    Ueffing, M.7    Hauck, S.M.8    Ekström, P.A.9
  • 36
    • 34347224404 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis in light-induced retinal degeneration
    • Perche O., Doly M. and Ranchon-Cole I. (2007). Caspase-dependent apoptosis in light-induced retinal degeneration. Invest. Ophthalmol. Vis. Sci. 48, 2753-2759.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 2753-2759
    • Perche, O.1    Doly, M.2    Ranchon-Cole, I.3
  • 37
    • 39849085938 scopus 로고    scopus 로고
    • Transient protective effect of caspase inhibitors in RCS rat
    • Perche O., Doly M. and Ranchon-Cole I. (2008). Transient protective effect of caspase inhibitors in RCS rat. Exp. Eye Res. 86, 519-527.
    • (2008) Exp. Eye Res. , vol.86 , pp. 519-527
    • Perche, O.1    Doly, M.2    Ranchon-Cole, I.3
  • 38
    • 0018990986 scopus 로고
    • Novel inhibitors of poly(ADPribose) synthetase
    • Purnell M.R. and Whish W.J. (1980). Novel inhibitors of poly(ADPribose) synthetase. Biochem. J. 185, 775-777.
    • (1980) Biochem. J. , vol.185 , pp. 775-777
    • Purnell, M.R.1    Whish, W.J.2
  • 39
    • 77955621380 scopus 로고    scopus 로고
    • Animal models and different therapies for treatment of retinitis pigmentosa
    • Rivas M.A. and Vecino E. (2009). Animal models and different therapies for treatment of retinitis pigmentosa. Histol. Histopathol 24, 1295-1322.
    • (2009) Histol. Histopathol , vol.24 , pp. 1295-1322
    • Rivas, M.A.1    Vecino, E.2
  • 40
    • 0037407743 scopus 로고    scopus 로고
    • Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors
    • Rotstein N.P., Politi L.E., German O.L. and Girotti R. (2003). Protective effect of docosahexaenoic acid on oxidative stress-induced apoptosis of retina photoreceptors. Invest. Ophthalmol. Vis. Sci. 44, 2252-2259.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 2252-2259
    • Rotstein, N.P.1    Politi, L.E.2    German, O.L.3    Girotti, R.4
  • 42
    • 33751239138 scopus 로고    scopus 로고
    • Apoptosis in retinal degeneration involves cross-talk between apoptosisinducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
    • Sanges D., Comitato A., Tammaro R. and Marigo V. (2006). Apoptosis in retinal degeneration involves cross-talk between apoptosisinducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc. Natl. Acad. Sci. USA 103, 17366-17371.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17366-17371
    • Sanges, D.1    Comitato, A.2    Tammaro, R.3    Marigo, V.4
  • 43
    • 33947543601 scopus 로고    scopus 로고
    • Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration
    • Sanz M.M., Johnson L.E., Ahuja S., Ekström P.A., Romero J. and van Veen T. (2007). Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration. Neuroscience 145, 1120-1129.
    • (2007) Neuroscience , vol.145 , pp. 1120-1129
    • Sanz, M.M.1    Johnson, L.E.2    Ahuja, S.3    Ekström, P.A.4    Romero, J.5    Van Veen, T.6
  • 44
    • 0019515454 scopus 로고
    • Induction of retinal degeneration in cats by methylnitrosourea and ketamine hydrochloride
    • Schaller J.P., Wyman M., Weisbrode S.E. and Olsen R.G. (1981). Induction of retinal degeneration in cats by methylnitrosourea and ketamine hydrochloride. Vet. Pathol. 18, 239-247.
    • (1981) Vet. Pathol. , vol.18 , pp. 239-247
    • Schaller, J.P.1    Wyman, M.2    Weisbrode, S.E.3    Olsen, R.G.4
  • 45
    • 67649510373 scopus 로고    scopus 로고
    • Review and update: Current treatment trends for patients with retinitis pigmentosa
    • Shintani K., Shechtman D.L. and Gurwood A.S. (2009). Review and update: current treatment trends for patients with retinitis pigmentosa. Optometry 80, 384-401.
    • (2009) Optometry , vol.80 , pp. 384-401
    • Shintani, K.1    Shechtman, D.L.2    Gurwood, A.S.3
  • 46
    • 0642377393 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation enzyme-1 as a target for neuroprotection in acute central nervous system injury
    • Skaper S.D. (2003). Poly(ADP-ribosyl)ation enzyme-1 as a target for neuroprotection in acute central nervous system injury. Curr. Drug Targets C.N.S. Neurol. Disord. 2, 279-291.
    • (2003) Curr. Drug Targets C.N.S. Neurol. Disord. , vol.2 , pp. 279-291
    • Skaper, S.D.1
  • 47
    • 34548417994 scopus 로고    scopus 로고
    • Chondroitinase ABC treatment enhances synaptogenesis between transplant and host neurons in model of retinal degeneration
    • Suzuki T., Akimoto M., Imai H., Ueda Y., Mandai M., Yoshimura N., Swaroop A. and Takahashi M. (2007). Chondroitinase ABC treatment enhances synaptogenesis between transplant and host neurons in model of retinal degeneration. Cell Transplant. 6, 493-503
    • (2007) Cell Transplant. , vol.6 , pp. 493-503
    • Suzuki, T.1    Akimoto, M.2    Imai, H.3    Ueda, Y.4    Mandai, M.5    Yoshimura, N.6    Swaroop, A.7    Takahashi, M.8
  • 49
    • 36749103711 scopus 로고    scopus 로고
    • Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse
    • Takeuchi K., Nakazawa M. and Mizukoshi S. (2008). Systemic administration of nilvadipine delays photoreceptor degeneration of heterozygous retinal degeneration slow (rds) mouse. Exp. Eye Res. 86, 60-69.
    • (2008) Exp. Eye Res. , vol.86 , pp. 60-69
    • Takeuchi, K.1    Nakazawa, M.2    Mizukoshi, S.3
  • 51
    • 27644496187 scopus 로고    scopus 로고
    • Delivery of neurotrophic factors and therapeutic proteins for retinal diseases
    • Thanos C. and Emerich D. (2005). Delivery of neurotrophic factors and therapeutic proteins for retinal diseases. Expert Opin. Biol. Ther. 5, 1443-1452.
    • (2005) Expert Opin. Biol. Ther. , vol.5 , pp. 1443-1452
    • Thanos, C.1    Emerich, D.2
  • 53
    • 0001971248 scopus 로고    scopus 로고
    • Phylogenetic and ontogenetic study of retinal lesions induced by Nmethyl-N-nitrosourea in animals
    • In Japanese, Abstract in English
    • Tsubura A., Yoshizawa K., Miki H., Oishi Y. and Fujii T. (1998). Phylogenetic and ontogenetic study of retinal lesions induced by Nmethyl-N-nitrosourea in animals. Anim. Eye Res. 17, 97-103. [In Japanese, Abstract in English]
    • (1998) Anim. Eye Res. , vol.17 , pp. 97-103
    • Tsubura, A.1    Yoshizawa, K.2    Miki, H.3    Oishi, Y.4    Fujii, T.5
  • 54
    • 31344471292 scopus 로고    scopus 로고
    • Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition
    • Uehara N., Miki K., Tsukamoto R., Matsuoka Y. and Tsubura A. (2006). Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition. Exp. Eye Res. 82, 488-495.
    • (2006) Exp. Eye Res. , vol.82 , pp. 488-495
    • Uehara, N.1    Miki, K.2    Tsukamoto, R.3    Matsuoka, Y.4    Tsubura, A.5
  • 56
    • 0025796794 scopus 로고
    • Retinitis pigmentosa and its models
    • Voaden M.J, (1991). Retinitis pigmentosa and its models. Prog. Retinal Eye Res. 10, 293-331.
    • (1991) Prog. Retinal Eye Res. , vol.10 , pp. 293-331
    • Voaden, M.J.1
  • 57
    • 67649794803 scopus 로고    scopus 로고
    • Calcium dysregulation induces apoptosisinducing factor release: Cross-talk between PARP-1- and calpainsignaling pathways
    • Vosler P.S., Sun D., Wang S., Gao Y., Kintner D.B., Signore A.P., Cao G. and Chen J. (2009). Calcium dysregulation induces apoptosisinducing factor release: Cross-talk between PARP-1- and calpainsignaling pathways. Exp. Neurol. 218, 213-220.
    • (2009) Exp. Neurol. , vol.218 , pp. 213-220
    • Vosler, P.S.1    Sun, D.2    Wang, S.3    Gao, Y.4    Kintner, D.B.5    Signore, A.P.6    Cao, G.7    Chen, J.8
  • 58
    • 38549117781 scopus 로고    scopus 로고
    • Preferential regeneration of photoreceptor from müller glia after retinal degeneration in adult rat
    • Wan J., Zheng H., Chen Z.L., Xiao H.L, Shen Z.J. and Zhou G.M. (2008). Preferential regeneration of photoreceptor from Müller glia after retinal degeneration in adult rat. Vision Res. 48, 223-234.
    • (2008) Vision Res. , vol.48 , pp. 223-234
    • Wan, J.1    Zheng, H.2    Chen, Z.L.3    Xiao, H.L.4    Shen, Z.J.5    Zhou, G.M.6
  • 60
    • 20444371989 scopus 로고    scopus 로고
    • High-level expression and purification of a nonmitogenic form of human acidic fibroblast growth factor in escherichia coli
    • Wu X., Su Z., Li X., Zheng Q., Huang Y. and Yuan H. (2005). High-level expression and purification of a nonmitogenic form of human acidic fibroblast growth factor in Escherichia coli. Protein Expr. Purif. 42, 7-11.
    • (2005) Protein Expr. Purif. , vol.42 , pp. 7-11
    • Wu, X.1    Su, Z.2    Li, X.3    Zheng, Q.4    Huang, Y.5    Yuan, H.6
  • 61
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Dickens M., Raingeaud J., Davis R.J. and Greenberg M.E. (1995). Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 62
    • 52449098753 scopus 로고    scopus 로고
    • Retina protective effect of acidic fibroblast growth factor after canceling its mitogenic activity
    • Xu H., Yang J.N., Li X.K., Zheng Q., Zhao W., Su Z.J. and Huang Y.D. (2008). Retina protective effect of acidic fibroblast growth factor after canceling its mitogenic activity. J. Ocul. Pharmacol. Ther. 24, 445-451.
    • (2008) J. Ocul. Pharmacol. Ther. , vol.24 , pp. 445-451
    • Xu, H.1    Yang, J.N.2    Li, X.K.3    Zheng, Q.4    Zhao, W.5    Su, Z.J.6    Huang, Y.D.7
  • 63
    • 34247350430 scopus 로고    scopus 로고
    • Microarray expression analysis of the early N-methy-N-nitrosoureainduced retinal degeneration in rat
    • Yang L., Li D., Chen J., Yang J., Xue L., Hu S. and Wu K. (2007). Microarray expression analysis of the early N-methy-N-nitrosoureainduced retinal degeneration in rat. Neurosci. Lett. 418, 38-43.
    • (2007) Neurosci. Lett. , vol.418 , pp. 38-43
    • Yang, L.1    Li, D.2    Chen, J.3    Yang, J.4    Xue, L.5    Hu, S.6    Wu, K.7
  • 65
    • 0032707946 scopus 로고    scopus 로고
    • Mechanisms of photoreceptor cell apoptosis induced by N-methyl-N-nitrosourea in Sprague-Dawley rats
    • Yoshizawa K., Nambu H., Yang J., Oishi Y., Senzaki H., Shikata N., Miki H. and Tsubura A. (1999). Mechanisms of photoreceptor cell apoptosis induced by N-methyl-N-nitrosourea in Sprague-Dawley rats. Lab. Invest. 79, 1359-1367.
    • (1999) Lab. Invest. , vol.79 , pp. 1359-1367
    • Yoshizawa, K.1    Nambu, H.2    Yang, J.3    Oishi, Y.4    Senzaki, H.5    Shikata, N.6    Miki, H.7    Tsubura, A.8
  • 67
    • 0029909261 scopus 로고    scopus 로고
    • N-methyl-N-nitrosourea-induced photoreceptor apoptosis in the mouse retina
    • Yuge K., Nambu H., Senzaki H., Nakao I., Miki H., Uyama M. and Tsubura A. (1996). N-methyl-N-nitrosourea-induced photoreceptor apoptosis in the mouse retina. In Vivo 10, 483-488.
    • (1996) Vivo , vol.10 , pp. 483-488
    • Yuge, K.1    Nambu, H.2    Senzaki, H.3    Nakao, I.4    Miki, H.5    Uyama, M.6    Tsubura, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.